Clinical trials: Sensitization, Central
Shoulder Pain
Efficacy of Manual Therapy and Exercise in Patients With Shoulder Adhesive Capsulitis. A Randomized Clinical Trial.
The efficacy of manual therapy and therapeutic exercise in patients suffering from adhesive capsulitis of the shoulder will be studied.
- Trial name
- MTEAC (NCT02976974)
- Testing
- Manual therapy, Therapeutic exercise
- Where
- 3 sites in Spain
- Volunteers
- 30 people
- Sponsor
- University of Malaga
Pelvic Pain, Vulvodynia
Psychosocial Factors and Central Sensitization in Chronic Pelvic Pain
The purpose of this study is to determine if the psychosocial factors in women with chronic pelvic pain are predisposing, precipitant or maintenance factors, and relate these factors with central sensitization and dysfunctional…
- Conditions
- Pelvic Pain, Vulvodynia, Pudendal Neuropathy
- Trial name
- NCT02856334
- Where
- 2 sites in Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Arthroplasty, Replacement, Knee, Pain, Postoperative
Central Sensitization and Alteration of Circulating Neurosteroid
For patients who underwent two-stage replacement of both knee joints (one knee surgery - one week term- the other knee surgery), postoperative pain and analgesic usage with patient-controlled analgesia (PCA) increased at the…
- Trial name
- NCT03298711
- Where
- South Korea
- Volunteers
- 69 people
- Sponsor
- Seoul National University Bundang Hospital
Chronic Pain
Immersive Virtual Reality and Central Sensitization in People With Chronic Pain
Patients with chronic low back pain from Dr. Robert Edwards' study at the Brigham \& Women's Pain Institute that examines sensory and pain perceptions in patients with chronic pain who use opioids will complete quantitative…
- Trial name
- NCT04609787
- Testing
- Immersive Virtual Reality
- Where
- United States
- Sponsor
- Tufts University
Fibromyalgia, Sedentary Behavior
Sedentary Status and Multidimensional Outcomes in Fibromyalgia
Fibromyalgia syndrome (FMS) is a chronic condition characterized by widespread musculoskeletal pain, fatigue, sleep disturbances, and functional limitations.
- Conditions
- Fibromyalgia, Sedentary Behavior, Kinesiophobia, Central Sensitisation
- Trial name
- NCT07358702
- Testing
- Assessment Only
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Izmir Democracy University
CBD, Healthy
CBD-Microglia PET Study
This study aims to examine the effect of cannabidiol (CBD) pre-treatment on brain microglial activation in healthy human subjects.
- Trial name
- NCT04398719
- Testing
- [11C]PBR28, Low-dose lipopolysaccharide, Intradermal Capsaicin
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Yale University
Chronic Plantar Fasciitis, Control Group
Frequency of Neuropathic Pain in Patients With Plantar Fasciitis
Study Design This prospective cross-sectional study was undertaken between November 2023 and March 2024. Written and verbal informed consent was obtained from all patients.
- Trial name
- NCT06348017
- Where
- Turkey (Türkiye)
- Volunteers
- 206 people, healthy volunteers welcome
- Sponsor
- Yozgat City Hospital
Plantar Fasciitis, Chronic
Comparative Effectiveness of Different Neural Mobilization Techniques in Plantar Fasciitis
BThis study will be designed to compare between the effect of adding posterior tibial nerve or saphenous nerve mobilization to the traditional physical therapy on pain intensity, foot function, pressure pain threshold, ankle…
- Trial name
- RCT (NCT07657533)
- Testing
- nerve mobilization, physical therapy, saphenous nerve mobilization
- Where
- Saudi Arabia
- Volunteers
- 60 people
- Sponsor
- Prince Sattam Bin Abdulaziz University
Chronic Shoulder Pain
Cognitive Behavioral Factors and Central Sensitization in Chronic Shoulder Pain
The objective of this study is to examine the relationship between symptoms of central sensitization (CS) and important cognitive behavioral and psychosocial factors in patients with chronic shoulder pain.
- Trial name
- NCT03838471
- Where
- Greece
- Volunteers
- 64 people
- Sponsor
- Technological Education Institute of Sterea Ellada
Lipedema
The Relationship Between Central Sensitization, Pain, and Psychosocial Factors in Individuals With Lipedema
This cross-sectional study will include women aged 18-75 with clinically diagnosed lipedema and healthy controls. Sociodemographic and clinical data will be collected, and participants will complete the Central Sensitization…
- Trial name
- NCT07240285
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Adenomyosis
Central Sensitization in Women With Adenomyosis: Prevalence, Risk Factors, and Therapeutic Failure
This is an observational, prospective, multicenter, non-profit study. The study aims to investigate the association between the Central Sensitization Inventory (CSI) score and the presence of Central Sensitization Syndrome (CSS)…
- Trial name
- ADENOCS (NCT07455721)
- Where
- 14 sites in Italy
- Volunteers
- 1,200 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Dysmenorrhea Primary, Central Sensitisation
Myofascial Release Technique in Women With Primary Dysmenorrhea
It has been found that women with dysmenorrhea have active trigger points, particularly in the rectus abdominis, oblique abdominal muscles, quadratus lumborum, and paraspinal muscles.
- Conditions
- Dysmenorrhea Primary, Central Sensitisation, Myofascial Trigger Point Pain, Menstrual Discomfort
- Trial name
- NCT06492148
- Testing
- Myofascial Release
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Gazi University
Low Back Pain
Uterine Position and Pain and Central Sensitization Parameters in Women With Chronic Low Back Pain
Female patients aged 18-75 years with chronic low back pain (lasting at least 3 months) will be included in the study. Demographic data including age, height, weight, educational status, marital status, and comorbidities will be…
- Trial name
- NCT07549009
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Rotator Cuff Tears, Central Sensitisation
Effect of Pregabalin on Shoulder Pain in Patients With Central Sensitization After Arthroscopic Rotator Cuff Repair
This study aims to investigate the effects of Pregabalin intake on shoulder pain management in patients with central sensitization undergoing arthroscopic rotator cuff repair.
- Conditions
- Rotator Cuff Tears, Central Sensitisation, Neuropathic Pain
- Trial name
- NCT06367998
- Testing
- Pregabalin
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- The Catholic University of Korea
Osteoarthritis
fMRI Evaluation of Pain Central Sensitization Phenomena in Subjects With Knee Osteoarthritis
The aim of this project is to investigate fMRI ability to identify pain central sensitization in chronic knee OA. Patients with high and low central sensitization and healthy control subjects will be included.
- Trial name
- NCT01700634
- Where
- Spain
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Parc de Salut Mar
Shoulder Pain
Suprascapular Nerve PRF for Central Sensitization and Neuropathic Pain
Chronic shoulder pain affects quality of life and is often associated with central sensitization, leading to treatment resistance.
- Trial name
- SSPRF-CS (NCT06857409)
- Testing
- pulsed radiofrequency
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gülçin Babaoğlu
Central Sensitisation, Cervical Spine Stenosis
Comparison of Pain, Sensitisation, Function and Quality of Life According to Stenosis Degree in Chronic Neck Pain
The cervical spine is a structure that bears the weight of the head and has important functions, but is susceptible to mechanical stress and degenerative processes.
- Trial name
- NCT06967415
- Testing
- Pain, central sensitization,functional status and quality of life.
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Izmir Democracy University
Joint Hypermobility Syndrome, Hypermobile Ehlers-Danlos Syndrome
Central Sensitization and Physical Activity in Adolescents With HSD/hEDS
Hypermobility Spectrum Disorder and hypermobile Ehlers-Danlos Syndrome (HSD/hEDS) is under-recognized and poorly understood and its management is therefore not clear.
- Trial name
- NCT05633225
- Testing
- Submax exercise test on a bicycle ergometer
- Where
- 2 sites in Sweden
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Vastra Gotaland Region
Chronic Shoulder Pain
Central Sensitization and Functional Outcomes in Chronic Shoulder Pain
This prospective observational cohort study aims to investigate whether baseline central sensitization and psychological factors predict functional outcomes following rehabilitation in individuals with chronic shoulder pain.
- Trial name
- SHOULDER-CS (NCT07654023)
- Testing
- Physiotherapy Rehabilitation Program
- Where
- Turkey (Türkiye)
- Volunteers
- 77 people
- Sponsor
- Ayşenur Yılmaz
Whiplash Injuries
Unraveling the Nature of Impaired Pain Inhibition in Patients With Chronic Whiplash-associated Disorders
The primary study aim is to unravel the nature of impaired pain inhibition during exercise in patients with chronic Whiplash-Associated Disorders (WAD).
- Trial name
- NCT01601912
- Testing
- Atomoxetine, Citalopram
- Where
- Belgium
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel