Clinical trials: Sensorimotor Disorder
Frail, Sensorimotor Deficits
Cognitive-motor Technology Rehabilitation in Frail Individuals
Dual performance, which involves the simultaneous execution of motor and cognitive tasks, is a fundamental aspect of everyday functioning.
- Trial name
- FIT4COG (NCT07292428)
- Testing
- Technological rehabilitation with robotic platfom and home telerehabilitation device, Conventional rehabilitation
- Where
- 2 sites in Italy
- Volunteers
- 80 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Osteoarthritis, Knee
Comparison of Progressive Motor Imagery and Sensorimotor Exercises in Knee Osteoarthritis
Osteoarthritis is the most common type of arthritis, which can affect all joints in the body and includes synovial inflammation, cartilage degeneration, osteophyte formation and bone remodeling in its pathophysiology.
- Trial name
- NCT05850793
- Testing
- Sensorimotor Exercise, Conventional Exercise, Progressive Motor Imagery Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Istanbul Medipol University Hospital
Parkinson Disease
Novel Paradigms of Deep Brain Stimulation for Movement Disorders
Investigators will enroll patients who are already selected to undergo deep brain stimulation surgery based on standard of care.
- Trial name
- NCT04563143
- Testing
- Novel DBS Stimulation
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- The Cleveland Clinic
Functional Neuroimaging
Sensorimotor Imaging for Brain-Computer Interfaces
The investigators will use fMRI to map movement activity in motor and somatosensory cortex using enriched imagery in people with chronic tetraplegia.
- Trial name
- NCT04723823
- Testing
- Motor or sensory imagery with fMRI
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Pittsburgh
Spinal Cord Diseases
Reorganization of Brain Functions in Patients With Cervical Myelopathy Using fMRI and MRS
Decompressive surgery to relieve symptoms of spinal cord compression due to dysfunction, such as arthritis, has proved variable in success.
- Trial name
- NCT00447343
- Testing
- Decompressive cervical spine surgery, fMRI and MRS scan
- Where
- Canada
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Parkinson Disease
Agility Training in Parkinson's Disease
To determine the effects of an unusually highly intensity and individualized sensorimotor and visuomotor agility exercise program on non-demented PD patients' clinical symptoms, mobility, and postural stability.
- Trial name
- NCT03189680
- Testing
- Exercise therapy
- Where
- Hungary
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Somogy Megyei Kaposi Mór Teaching Hospital
Parkinson Disease, Stroke
Mobility Rehab, a Therapist-assisted System for Gait Rehabilitation
Phase II of this study includes a pragmatic clinical trial which will take place at Northwest Rehabilitation Associates (NWRA) in Salem, OR to verify the efficacy of the system in a physical therapy clinic.
- Conditions
- Parkinson Disease, Stroke, Multiple Sclerosis, Gait Disorders, Neurologic
- Trial name
- NCT03869879
- Testing
- Feedback-assisted physical therapy, Traditional physical therapy
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Oregon Health and Science University
Stroke
Effect of Multisite High-definition Transcranial Direct Current Stimulation Targeting Sensorimotor Network
Transcranial direct current stimulation (tDCS) has been applied to facilitate cortical excitability in stroke populations, as increasing evidence suggests that clinical recovery from stroke is attributed to neuroplastic…
- Trial name
- NCT06648954
- Testing
- multisite HD-tDCS, Conventional tDCS
- Where
- Hong Kong
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Loss of Consciousness, Parkinson Disease
Brain Networks and Consciousness
General anesthesia (GA) is a medically induced state of unresponsiveness and unconsciousness, which millions of people experience every year.
- Conditions
- Loss of Consciousness, Parkinson Disease, Essential Tremor, Anesthesia
- Trial name
- NCT04502550
- Testing
- Propofol
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- University of Texas Southwestern Medical Center
Voice Disorders
Dextromethorphan to Treat Patients With Voice Spasms
This study will examine how dextromethorphan, a drug that alters reflexes of the larynx (voice box), might change voice symptoms in people with voice disorders due to uncontrolled laryngeal muscle spasms.
- Trial name
- NCT00055549
- Testing
- Dextromethorphan, Lorazepam
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Writer's Cramp
Sensorimotor Mapping in Patients With Writer's Cramp
Writer's cramp (WC) is a form of focal dystonia, a movement disorder characterized by sustained or intermittent muscle contractions causing abnormal, often repetitive movements, postures, or both.
- Trial name
- IWCToxin (NCT03085745)
- Testing
- Transcranial Magnetic Stimulation (TMS)
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Grenoble
Stroke
Effectiveness of Robot-Assisted Structured Foot-Ankle Sensorimotor Training in Stroke Patients
Introduction: Stroke is a leading cause of long-term disability worldwide. Persistent lower-extremity motor and somatosensory impairments after stroke commonly limit walking and balance despite rehabilitation.
- Trial name
- NCT07091045
- Testing
- Robot-Assisted Foot-Ankle Training, Conventional Foot-Ankle Training
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Medipol University
Stroke, Sensorimotor Impairment
Learning in Stroke
After a stroke, plasticity occurs in the brain from microscopic to network level with positive but also negative consequences for functional recovery.
- Trial name
- NCT05511467
- Testing
- Visuomotor learning task
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Epilepsy
An Examination of Cognitive and Sensorimotor Processes in Patients With Epilepsy
The overall goal of this project is to better understand the micro-physiology of human epilepsy and cognition using the intracranial electroencephalogram (iEEG), electrical brain stimulation, functional magnetic resonance imaging…
- Trial name
- NCT00859794
- Testing
- fMRI, Neuropsychological Testing, Additional electrode implantation
- Where
- United States
- Volunteers
- 450 people
- Sponsor
- Northwell Health
Osteoathritis and Sleep
Changes Of Sleep on the Sensoriomotor and Cytokine In Patients With Osteoarthritis
Osteoarthritis (OA) is one of the major health problems and their prevalence has increased in recent decades. It has been shown that OA causes negative effects on sleep and that these changes in sleep see to be correlated with…
- Trial name
- NCT01422967
- Testing
- Balance and muscle strength
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Sao Carlos
Indigestion, Diabetes Mellitus
Effects of Ondansetron on Gastrointestinal Sensorimotor Dysfunctions in Diabetes Mellitus and Dyspepsia
Researchers are trying to understand why people with indigestion and diabetes mellitus have gastrointestinal symptoms and in particular to understand whether symptoms are related to increased sensitivity to nutrients in the small…
- Trial name
- NCT03865290
- Testing
- Ondansetron 8mg
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Spinal Cord Injuries
Epidural Stimulation in Chronic Spinal Cord Injury Patients
Investigators propose to demonstrate that epidural stimulation (ES) can be used to recover significant levels of autonomic control of cardiovascular, urinary and sexual function as well as the ability to voluntarily control leg…
- Trial name
- NCT05690074
- Testing
- Spectra Wave Writer™ Spinal Cord Stimulator System
- Where
- Czechia
- Volunteers
- 5 people
- Sponsor
- University Hospital, Motol
Stroke
Virtual Reality and Field Training to Enhance Community Walking After Stroke
While stroke survivors discharged from rehabilitation present with some recovery in mobility, their ability to ambulate in the community remains limited.
- Trial name
- NCT04559373
- Testing
- Virtual Reality and Field Training (VRFT)
- Where
- 2 sites in Canada
- Volunteers
- 40 people
- Sponsor
- McGill University
Epileptic Seizure, Epilepsy Intractable
REC2Stim as a Treatment for Refractory Epilepsy in the Primary Sensorimotor Cortex.
People with central lobe epilepsy (CLE), with seizures arising from the primary sensorimotor cortex, typically show a high rate of convulsive seizures that do not respond to anti-epileptic drugs, but have a large impact on…
- Conditions
- Epileptic Seizure, Epilepsy Intractable, Motor Seizure
- Trial name
- REC2Stim (NCT04158531)
- Testing
- ECoG sensing and stimulation
- Where
- Netherlands
- Volunteers
- 10 people
- Sponsor
- UMC Utrecht
Stroke Sequelae, Stroke ( 3 Months After Onset)
Clinical Implementation of Multichannel Functional Electrical Stimulation Device for Gait Rehabilitation in Subchronic Stroke: A Feasibility Study
The goal of this interventional study is to evaluate the effect of multichannel functionnal electrical stimulation for subchronic stroke gait rehabilitation.
- Trial name
- NCT07211672
- Testing
- Multichannel functionnal electrical stimulation
- Volunteers
- 5 people
- Sponsor
- TOPMED