Clinical trials: Sensorimotor Disorder
Zika Virus Infection
Sensorimotor Outcomes of Children Exposed to Foetal Zika Virus Infection
Introduction: It is estimated that more than one million Brazilians were infected by zika virus in the last two years. Brazilian researchers first noted the virus's potential association with microcephaly.
- Trial name
- NCT03679728
- Testing
- First trimester, Second trimester
- Where
- Brazil
- Volunteers
- 31 people
- Sponsor
- University of Sao Paulo
Wrist Injury, Hand and Upper Limb Trauma
Virtual Reality-based Rehabilitation for Traumatic Hand and Wrist Injuries
This randomized controlled trial aims to evaluate the effectiveness of immersive virtual reality (VR)-based Action Observation Therapy (AOT) as an adjunct to conventional rehabilitation in patients with traumatic wrist and hand…
- Conditions
- Wrist Injury, Hand and Upper Limb Trauma, Hand and Forearm Trauma, Muskuloskeletal Diseases
- Trial name
- AOT-VR-HAND (NCT07633769)
- Testing
- Immersive Virtual Reality Action Observation Therapy, Conventional Rehabilitation
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- University of Malaga
Gait Disorder, Sensorimotor
Pilot Study for Patient-cooperative Control Strategies for Actuated Transfemoral Prostheses
This pilot study investigates the feasibility of novel control strategies for actuated transfemoral prostheses. Several parameters from gait analysis (including motion-capture and ground reaction force measurements) are analyzed.
- Trial name
- NCT02310841
- Testing
- ANGELAA
- Where
- Switzerland
- Volunteers
- 1 people
- Sponsor
- Swiss Federal Institute of Technology
Parkinson, Dystonia
Sensorimotor Integration in Monogenic Parkinson-dystonia Syndromes
Hereditary Parkinson and dystonia syndromes are rare, as are people who carry the predisposition for Parkinson or dystonia but do not have symptoms.
- Conditions
- Parkinson, Dystonia, DYT3, DYT5
- Trial name
- SensoMo-PD (NCT05713721)
- Testing
- Transcranial magnetic stimulation (TMS), Video-based clinical examination, 24 hours drug withdrawal of dopaminergic medication
- Where
- Germany
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital Schleswig-Holstein
Parkinson Disease
Precision Sensorimotor Neurorehabilitation Through Personalized Stimulation Loops
Parkinson's disease (PD) is a neurodegenerative disease that affects about 1% of the elderly population and accounts for substantial disability and health care costs.
- Trial name
- StimuLOOP-PD (NCT06608875)
- Testing
- Hyper-personalized feedback (HPF intervention), Targeted auditory stimulation during sleep (TASS verum intervention)
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- University of Zurich
Breast Neoplasm, Exercise
Sensorimotor Training Using Whole Body Vibration Exercise to Reduce Chemotherapy-induced Peripheral Neuropathy
CIPN is induced by neurotoxic chemotherapeutic agents and manifests with sensory and/or motor deficits. It is associated with significant disability and poor recovery.
- Trial name
- Sensi-Ex (NCT05361018)
- Testing
- Whole Body Vibration exercise - WBV
- Where
- Sweden
- Volunteers
- 44 people
- Sponsor
- Karolinska Institutet
Stroke, Aphasia
Donepezil in Chronic Poststroke Aphasia: a Randomized Controlled Trial
Aphasia (impairment of language function due to brain damage)may be treated with speech-language therapy and drugs. Several drugs have been studied but with limited success.
- Trial name
- NCT00196690
- Testing
- Donepezil
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Gabinete Berthier y Martínez
Schizophrenia, Schizo Affective Disorder
Memantine Effects on Sensorimotor Gating and Neurocognition in Schizophrenia
This application seeks to determine if neurophysiological metrics of memantine (MEM)-enhanced early auditory information processing (EAIP) in schizophrenia (SZ) mediate gains in auditory processing fidelity (APF) and auditory…
- Conditions
- Schizophrenia, Schizo Affective Disorder, Schizoaffective Disorder, Healthy
- Trial name
- NCT03860597
- Testing
- Memantine
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Frail, Sensorimotor Deficits
Cognitive-motor Technology Rehabilitation in Frail Individuals
Dual performance, which involves the simultaneous execution of motor and cognitive tasks, is a fundamental aspect of everyday functioning.
- Trial name
- FIT4COG (NCT07292428)
- Testing
- Technological rehabilitation with robotic platfom and home telerehabilitation device, Conventional rehabilitation
- Where
- 2 sites in Italy
- Volunteers
- 80 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
Clinical Trial of SB-509 in Subjects With Diabetic Neuropathy
The purpose of the study is to evaluate the clinical effects of the investigational drug, SB-509, in subjects with diabetic neuropathy.
- Conditions
- Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Diabetic Polyneuropathy
- Trial name
- NCT01079325
- Testing
- SB-509, Saline
- Where
- 31 sites in United States
- Volunteers
- 170 people
- Sponsor
- Sangamo Therapeutics
Diabetic Polyneuropathy
Surgical Decompression for Diabetic Neuropathy in the Foot
The purpose of the study is to determine whether or not surgical decompression of the common peroneal, tibial, and deep peroneal nerves in the legs of persons with diabetic peripheral neuropathy is effective treatment.
- Trial name
- NCT01006915
- Testing
- Surgery
- Where
- Canada
- Volunteers
- 21 people
- Sponsor
- Timothy J. Best Medicine Professional Corporation
Healthy
Pregabalin and Colonic Function
This study is being done to evaluate the effects of pregabalin, a drug approved for anticonvulsive therapy and for neuropathic pain, on colonic and sensory functions in healthy individuals.
- Trial name
- NCT01094808
- Testing
- Pregabalin, Bowel preparation
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Autism Spectrum Disorder
Characterization of (A)Typical Sensorimotor Pathways in Individuals With Autism
The goal of this interventional study is to understand whether sensorimotor skills could represent an endophenotype for autism, i.e.
- Trial name
- MovAUT (NCT07389720)
- Testing
- clinical assessment, Neuropsychological examination, Neurophysiological evaluation
- Where
- Italy
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Healthy, Dystonia
Abnormal Movements, Cerebellum and Sensorimotor : Oculomotor Study
Dystonia is a movement disorder characterized by involuntary, sustained, often repetitive muscle contractions of opposite muscles that lead to abnormal twisting movements or odd postures.
- Conditions
- Healthy, Dystonia, Parkinson Disease
- Trial name
- MOUVADOC (NCT01495897)
- Testing
- Tracking eye movement, Tracking eye movement under deep brain stimulation
- Where
- France
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Stroke
Clinical Validation of an Instrumented Glove for Sensorimotor Rehabilitation
The goal of this clinical trial is to evaluate the DESC-Glove, an instrumented glove developed for sensorimotor rehabilitation in individuals recovering from a stroke, utilizing non-invasive vibrational feedback.
- Trial name
- NCT06649968
- Testing
- DESC-Glove (active), Traditional rehabilitation
- Where
- 6 sites in Italy
- Volunteers
- 47 people
- Sponsor
- Christian Cipriani
Achalasia
Sensorimotor Dysfunction in Achalasia
This study is being done to assess the esophageal muscle (swallowing tube) in patients with and without achalasia to further understand and help direct the treatment for patients with achalasia.
- Trial name
- NCT02434991
- Testing
- Barostat
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Mayo Clinic
Parkinson Disease
Novel Paradigms of Deep Brain Stimulation for Movement Disorders
Investigators will enroll patients who are already selected to undergo deep brain stimulation surgery based on standard of care.
- Trial name
- NCT04563143
- Testing
- Novel DBS Stimulation
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- The Cleveland Clinic
Upper Limb Sensorimotor Deficits
Feasibility and Cost of Robot-assisted Upper Limb Rehabilitation With Different Levels of Supervision
Upper limb impairments are often a result of neurological or traumatic injuries (e.g., stroke, traumatic brain injuries). These impairments may decrease independence in performing activities of daily living, severely affecting…
- Trial name
- RHB Clinic (NCT06725784)
- Testing
- ReHandyBot
- Where
- 2 sites in Switzerland
- Volunteers
- 100 people
- Sponsor
- Swiss Federal Institute of Technology
Unilateral Spatial Neglect (USN)
The Effects of Playing Live Music in Music Therapy/Occupational Therapy Co-treatment on Unilateral Spatial Neglect
Investigators hypothesize, based on anecdotal evidence to date, that active music making interventions conducted on a patient's neglected side will result in improved attention to that side and that this will be measurable within…
- Trial name
- NCT02919722
- Testing
- Music Therapy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- NYU Langone Health
Stroke Sequelae
Effect of Air Splints on Sensoriomotor Disturbances of the Affected Upper Extremity and Trunk Control in the Adult Post-stroke Patient
Objective: Sensory impairment in the affected upper limb occurs in approximately 50% of post-stroke patients and negatively impacts functional capacity and quality of life.
- Trial name
- NCT07029061
- Testing
- Air splints
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Alfonso X El Sabio University