Clinical trials: Sensorineural Hearing
Cochlear Implants, Bilateral Sensorineural Hearing Loss
Assessing the Effect of Computer-based Auditory Training on Adult Cochlear Implant Speech and Quality-of-life Outcomes
The purpose of this study is to compare the effectiveness of a free computer-based auditory training program, Sound Success (Advanced Bionics, Valencia, CA), with the current standard of care of patient-directed auditory training…
- Trial name
- NCT06607146
- Testing
- Sound Success, Standard of Care
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Mayo Clinic
Sensorineural Hearing Loss, Perceived Hearing Loss
Clinical Evaluation of Hearing Aid OTC Self-Assessment Methods for Adults With Perceived Mild-to-Moderate Hearing Loss
The goal of this clinical trial is to compare two methods of self assessment of hearing with conventional audiometry in an OTC Hearing Aid for adults with perceived mild to moderate hearing loss.
- Conditions
- Sensorineural Hearing Loss, Perceived Hearing Loss, Hearing Impairment
- Trial name
- NCT07738237
- Testing
- OTC Hearing Aid Self Fitting App, Audiometry
- Where
- Australia
- Volunteers
- 24 people
- Sponsor
- Rehear Audiology Company LTD
Hearing Loss, Sensorineural, Cochlear Implant
MED-EL Remote Care Multi-Center Feasibility Study
MED-EL Remote Care is a way for MED-EL cochlear implant users to check their hearing and cochlear implant device from any location, without the need for a scheduled, in-person appointment with their audiologist.
- Conditions
- Hearing Loss, Sensorineural, Cochlear Implant, Cochlear Implant Recipients, Hearing Disorders
- Trial name
- NCT05973669
- Testing
- MED-EL Remote Care
- Where
- 5 sites in United States, Canada
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Med-El Corporation
Hearing Impairment, Sensorineural
A Feasibility Study Evaluating the Performance of Focused Multipolar Stimulation and Sound Coding in Adults.
The purpose of this early feasibility study is to explore several facets of hearing performance of Focused Multipolar stimulation in adult cochlear implant users.
- Trial name
- SASC (NCT05641155)
- Testing
- Focused Multipolar Stimulation (FMS) strategy
- Where
- 5 sites in United States, Belgium
- Volunteers
- 18 people
- Sponsor
- Cochlear
Conductive Hearing Loss, Sensorineural Hearing Loss
Middle Ear Optical Coherence Tomography Imaging and Vibrometry in Patients With Hearing Loss
This study involves imaging ears with hearing loss with a new system that allows the user to see the middle ear bones and measure their movement in response to sound.
- Trial name
- NCT07732920
- Testing
- OCT - clear
- Where
- 2 sites in Canada
- Volunteers
- 500 people
- Sponsor
- Audioptics Medical Incorporated
Sudden Sensorineural Hearing Loss (SSNHL), Prediabetes / Type 2 Diabetes
CGM-guided Patch Pump vs Basal-Bolus Injection for Steroid-Induced Hyperglycemia in Sudden Sensorineural Hearing Loss: SHIP Trial
This exploratory randomized controlled trial evaluates whether a CGM-guided temporary patch pump (CareLevo CSII) reduces glucocorticoid-induced hyperglycemia (GIH) compared to a Lantus-based basal-bolus injection (MDI) regimen in…
- Trial name
- SHIP (NCT07652528)
- Testing
- CareLevo Patch-type Insulin Pump, Insulin Glargine U-100 (Lantus), Fast-acting Insulin Aspart (Fiasp)
- Volunteers
- 50 people
- Sponsor
- Hallym University
Cochlear Implant, Sensorineural Hearing Loss
The Effect of Anatomy-based Fitting on the Perception of Speech in Noise and Music in Single-sided Deaf Cochlear Implant Users
The present study evaluates the effect of anatomy-based fitting on speech perception in noise and music perception in newly implanted single-sided deaf (SSD) CI recipients.
- Conditions
- Cochlear Implant, Sensorineural Hearing Loss, Single Sided Deafness
- Trial name
- NCT07703800
- Testing
- Anatomy-based fitting, Default fitting
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- University Hospital, Antwerp
Hearing Loss, Sensorineural
Intracochlear Platelet-rich Fibrin Application in Cochlear Implantation
Fibrosis due to surgical trauma is a common problem with cochlear implants. Fibrosis limits the effectiveness of implant and increases the power consumption.
- Trial name
- NCT05215197
- Testing
- intracochlear platelet rich fibrin administration
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people
- Sponsor
- Pamukkale University
Hearing Loss, Bilateral Sensorineural, Pulmonary Function
Comparison of Pulmonary Functions and Respiratory Muscle Strength Between Children With Hearing Impairment and Healthy Peers
This study aims to compare pulmonary function and respiratory muscle strength between children with hearing impairment and their healthy peers.
- Conditions
- Hearing Loss, Bilateral Sensorineural, Pulmonary Function, Respiratory Muscle Strength, Children
- Trial name
- NCT07421349
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Bilateral Sensorineural Hearing Loss
Noise Reduction With Hearing Aids
The purpose of this study is to use an optimized version of the SEDA algorithm (SEDA-HA) for hearing aids to evaluate the benefit for listeners with varying degrees of hearing loss in realistic environments and evaluate its…
- Trial name
- NCT07700043
- Testing
- Speech Enhancement using Decomposition Approach-Hearing Aid (SEDA-HA) algorithm, Hearing aid (HA) prototype with SEDA-HA algorithm
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- NYU Langone Health
Sensorineural Hearing Loss
Safety of Autologous Stem Cell Infusion for Children With Acquired Hearing Loss
To determine if autologous human umbilical cord blood infusion in children with acquired hearing loss is safe, feasible, improves inner ear function, audition and language development.
- Trial name
- NCT02038972
- Testing
- Autologous Stem Cells
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- James Baumgartner, MD
Sensorineural Hearing Loss, Fibrosis
Evaluation of Electrode-modiolus Distance and Cochlear Fibrosis Using Depth Sounding and Spectroscopy Tools
Cochlear fibrosis development can compromise the success and the outcomes of the cochlear implantation (CI) thus affecting the quality of life of the implanted patient.
- Trial name
- TIMAGING (NCT05402969)
- Testing
- Transimedance Matrix measurements, Depth sounding and spectroscopy, Cone Beam Computer Tomography
- Where
- France
- Volunteers
- 180 people
- Sponsor
- University Hospital, Montpellier
Cochlear Implant, Sensorineural Hearing Loss
Anatomy-Based Fitting in Bimodal Cochlear Implant Users
The purpose of the study is to investigate the effect of an anatomy-based frequency distribution in comparison to a default frequency distribution in bimodal CI patients, i.e.
- Conditions
- Cochlear Implant, Sensorineural Hearing Loss, Hearing Aid
- Trial name
- NCT07691853
- Testing
- Anatomy-based fitting, Default fitting
- Where
- 2 sites in Belgium
- Volunteers
- 25 people
- Sponsor
- Universitair Ziekenhuis Brussel
OTOF Gene Mutation, DFNB9
A Phase I/II Clinical Trial With SENS-501 in Children Suffering From Severe to Profound Hearing Loss Due to Otoferlin (OTOF) Mutations
This study intends to assess safety, tolerability, and efficacy of SENS-501 in children between the ages of 6-31 months with pre-lingual hearing loss due to a mutation in the Otoferlin gene.
- Conditions
- OTOF Gene Mutation, DFNB9, Congenital Deafness, Hearing Disorders
- Trial name
- AUDIOGENE (NCT06370351)
- Testing
- SENS-501 administration
- Where
- 2 sites in Australia, France
- Volunteers
- 12 people
- Sponsor
- Sensorion
Sensorineural Hearing Loss, Bilateral Hearing Loss
Long-term Follow-up of a Cochlear Implant With Dexamethasone Eluting Electrode Array
A long-term follow-up of Cochlear's cochlear implant electrode array which passively elutes dexamethasone for a defined period of time to help reduce inflammatory responses.
- Trial name
- CI-DEX-LTFU (NCT06936449)
- Testing
- CI632D, CI632
- Where
- 3 sites in United States
- Volunteers
- 19 people
- Sponsor
- Cochlear
Sensorineural Hearing Loss, Cochlear Implantation
Perceptual Adaptation Following Cochlear Implantation (Aim 3a)
The goal of this study is to study the adaptation process in newly implanted Single-Sided Deaf Cochlear Implant (SSD-CI) users. Subjects will use four frequency maps for the first month after CI activation.
- Conditions
- Sensorineural Hearing Loss, Cochlear Implantation, Perceptual Adaptation
- Trial name
- NCT07039435
- Testing
- Alternative Frequency Mapping
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- NYU Langone Health
Hearing Loss, Sensorineural
Evaluation of an Open-source Speech-processing Platform
Determining acceptability and usability of a wearable open-source speech processing platform (Master Hearing Aid) developed for hearing-aid research
- Trial name
- EOSP (NCT03686046)
- Testing
- Exploratory use
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Cochlear Implants, Sensorineural Hearing Loss
Anatomy-Based Fitting in Unexperienced Cochlear Implant Users
Severe to profound hearing loss affects 0,8% of the global population. For these people, a conventional hearing aid often does not provide sufficient benefit. However, these people can benefit from a cochlear implant (CI).
- Trial name
- ABFmulti (NCT05451628)
- Testing
- Default CI fitting, Anatomy-based CI fitting
- Where
- 2 sites in Belgium
- Volunteers
- 40 people
- Sponsor
- Universitair Ziekenhuis Brussel
Bilateral Sensorineural Hearing Loss, Speech and Language Development Delay Due to Hearing Loss
Neural Prediction to Enhance Language
The language outcome of children receiving cochlear implantation to address bilateral sensorineural hearing loss is more variable than that of typical hearing children.
- Conditions
- Bilateral Sensorineural Hearing Loss, Speech and Language Development Delay Due to Hearing Loss, Social Communication
- Trial name
- NCT05962359
- Testing
- Parent-Implemented Communication Treatment
- Where
- United States
- Volunteers
- 700 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Hearing Loss, Sensorineural
Standard Post Market Clinical Follow-up (PMCF) Study WSA 2026
The purpose of the study is to follow-up on a released low-risk device as part of standard PMCF activities.
- Trial name
- NCT07667140
- Testing
- In-the-Ear Hearing Aid, Own hearing aid
- Where
- Germany
- Volunteers
- 24 people
- Sponsor
- WSAUD A/S