Clinical trials: Sensory Function
Hearing Loss, Sensorineural, Cochlear Hearing Loss
Evaluation of the CochSyn Device in Clinical Practice
This study investigates a new type of auditory evoked brain potentials for the quantification and classification of peripheral hearing damage (The CochSyn Test).
- Conditions
- Hearing Loss, Sensorineural, Cochlear Hearing Loss, Cochlear Synaptopathy, DFNA9
- Trial name
- Earditech 2 (NCT07091071)
- Testing
- CochSyn device
- Where
- 3 sites in Belgium
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- University Ghent
Cornea; Sense Loss
Investigation in Corneal Sensation
The aim is to find out more about how corneal sensory fibres react to different types of stimuli (liquid / tactile / nylon thread) and how this can be consciously perceived by the individual.
- Trial name
- NCT04045509
- Testing
- Liquid Jet Esthesiometer Prototype, Tactile Esthesiometer Prototype, Cochet Bonnet esthesiometer
- Where
- Switzerland
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Daniela Nosch
Sensorineural Hearing Loss
Phase I/IIa Study Evaluating Safety and Efficacy of an Intratympanic Dose of PIPE-505 in Subjects With Hearing Loss
This is a randomized, double-blind study of PIPE-505, or placebo, in subjects with hearing loss associated with speech-in-noise impairment.
- Trial name
- NCT04462198
- Testing
- PIPE-505
- Where
- 8 sites in United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Contineum Therapeutics
Eye Diseases
iSCREEN-study: Online Nurse-assisted Eye-screening in Home Healthcare
The aim of this study is to investigate the cost-effectiveness of a nurse-assisted online eye-screening in home healthcare in reducing eye complaints.
- Trial name
- NCT06058637
- Testing
- Eye screening
- Where
- Netherlands
- Volunteers
- 234 people, healthy volunteers welcome
- Sponsor
- Amsterdam UMC, location VUmc
Chronic Suppurative Otitis Media, Hearing Impairment
Prevalence and Associations of Paediatric Chronic Suppurative Otitis Media and Hearing Impairment in Rural Malawi
This community-based cross-sectional survey will estimate the frequency and risk factors of Chronic Suppurative Otitis Media and Hearing Impairment in Children ages 4-6 years in the Chikwawa District.
- Trial name
- NCT02779907
- Testing
- No Intervention
- Where
- Malawi
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Liverpool School of Tropical Medicine
Hearing Loss
Development and Assessment of a Spanish-Language Hearing Loss Toolkit for Self-Management
The objective of this application is to develop and evaluate Spanish-language hearing education materials for adults. Our hypothesis is that participants will demonstrate better understanding of their hearing loss and associated…
- Trial name
- NCT04534387
- Testing
- Spanish-Language Hearing Loss Toolkit for Self-Management, American Speech-Language-Hearing Association (ASHA) Audiology Series Spanish Language Handouts
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Healthy
Local Changes of Skin Characteristics After an Application of a Topical Product With a Warming or Cooling Effect
The use of topical over-the-counter (OTC) products with a warming or cooling effect is widespread in the fields of sport, physiotherapy and in private households.
- Trial name
- SRPT (NCT03016221)
- Testing
- Axanova hot gel, Axanova activ gel, Perskindol Dolo Gel
- Where
- Switzerland
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Applied Sciences and Arts of Southern Switzerland
Refractive Error, Visual Impairment
The Baltimore Reading and Eye Disease Study
The Baltimore Reading and Eye Disease Study (BREDS) is a two year study to determine the prevalence of vision problems in an early school age population with reading difficulty.
- Conditions
- Refractive Error, Visual Impairment, Convergence Insufficiency, Reading Disabilities
- Trial name
- BREDS (NCT02607384)
- Testing
- Eyeglass wearing, Orthoptic exercises, Specialist referral
- Volunteers
- 328 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Hearing Loss, Presbycusis
Predicting Success With Hearing Aids
The primary complaint of individuals with hearing loss is difficulty understanding speech in the presence of background noise. Although hearing aids help individuals understand speech in background noise better, there is a high…
- Trial name
- NCT00371449
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Unilateral Cerebral Palsy
Multi Sensory Stimulation And Priming (MuSSAP) in Infants at Risk of Unilateral Cerebral Palsy
A pilot randomized clinical trial exploring the effect of a Multi Sensory Stimulation And Priming (MuSSAP) training on improving manual ability in infants at risk of developing unilateral Cerebral Palsy.
- Trial name
- MuSSAP (NCT05533476)
- Testing
- Multi Sensory Stimulation and Priming, Intensive Usual Care (Upper Limb)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Sint Maartenskliniek
Blindness, Acquired
AI-Powered Artificial Vision for Visual Prostheses
Visual impairment is one of the ten most prevalent causes of disability and poses extraordinary challenges to individuals in our society that relies heavily on sight.
- Trial name
- NCT06117332
- Testing
- Visual prosthesis
- Where
- 2 sites in United States, Spain
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of California, Santa Barbara
Nerve Block
Continuous Femoral Nerve Blocks: Relative Effects of Basal Infusion and Bolus Doses on Sensory and Motor Function
This is a research study to determine if the way local anesthetic- or numbing medication- is delivered through a tiny tube next to the nerves that go to the thigh affects the strength and sensation in the thigh.
- Trial name
- NCT01144559
- Testing
- Continuous Infusion, Bolus Administered
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Smell Dysfunction, Taste Dysfunction
Post-Covid-19 Patients Follow-up Study
Taste, smell, trigeminal and salivary function is impacted in post-COVID-19 patients
- Conditions
- Smell Dysfunction, Taste Dysfunction, Trigeminal Dysfunction, Salivary Dysfunction
- Trial name
- COVID-19 (NCT07571382)
- Testing
- Smell training
- Where
- Norway
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Healthy
Metabolomic Response to Meal Ingestion
The investigators have recently shown that postprandial sensations correlate with changes in circulating metabolites after a meal ingestion; however this phenomenon was demonstrated with a meal load up to the level of tolerance…
- Trial name
- NCT03383250
- Testing
- Normal meal
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Age-related Hearing Loss
Prediction of Age-Related Hearing Loss Based on Comprehensive Risk Factors
This study aims to develop a predictive model for age-related hearing loss (ARHL) based on multi-source risk factors and artificial intelligence techniques.
- Trial name
- NCT07612618
- Testing
- Not applicable- observational study
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Hearing Loss
Hearing Aid Algorithms for Sudden Sounds
This study explores the impact of hearing aid settings for managing sudden sounds on speech comprehension and recall in individuals with hearing loss.
- Trial name
- NCT06340919
- Testing
- Sudden Sound Reduction Setting
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Purdue University
Infant Development, Sensory Disorder
The Prechtl's General Movement Assessment, Hammersmith Infant Neurological Examination and Sensory Profile-2
In the Neonatal Intensive Care Unit (NICU), infants encounter many sensory stimuli (excessive noise, bright lights, painful medical applications, etc.) that are not present in the uterus.
- Conditions
- Infant Development, Sensory Disorder, Sensory Processing Disorder, Motor Delay
- Trial name
- highrisk (NCT05217199)
- Testing
- Measurements
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Spinal Cord Injury, Stroke
Investigating Techniques to Enhance the Sense of Embodiment in Immersive Virtual Reality
Embodiment is an important aspect of virtual reality because it affects how natural and engaging the experience feels and can influence performance and learning in VR-based applications, including rehabilitation [McAnally \&…
- Conditions
- Spinal Cord Injury, Stroke, Healthy
- Trial name
- NCT07870044
- Testing
- Immersive Virtual Reality Embodiment Manipulations
- Where
- Italy
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Glucose Tolerance, Appetite Sensations
Effects of Nopal Fractions on Postprandial Glucose Regulation and Appetite Variables in Healthy Humans
Postprandial effects of Nopal fractions on glucose and appetite regulation will be investigated in healthy humans, in a randomised controlled crossover trial
- Trial name
- NCT04439630
- Testing
- Nopal fractions, Test product without the active components
- Where
- Sweden
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Lund University
Hearing Loss, Normal Hearing
Assessment of Novel Sound Changing Principles in Hearing Instruments to Determine Their Application - 2018_16
An EEG study using continuous speech stimuli to assess neural language processing in a hearing impaired population. Participants listen to short radio excerpts in different Signal to Noise Ratios (SNR) and answer comprehension…
- Trial name
- NCT03578471
- Testing
- Hearing Aid without NR and BF, Hearing Aid with NR, Hearing Aid with BF
- Where
- Switzerland
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Sonova AG