Clinical trials: Sensory Function
Pain, Peripheral Neuropathy
MC5-A Scrambler Therapy or TENS Therapy in Treating Patients With Chemotherapy-Induced Peripheral Neuropathy
This randomized clinical trial studies how well MC5-A scrambler therapy or transcutaneous electrical nerve stimulation (TENS) therapy work in treating patients with chemotherapy-induced peripheral neuropathy (a nerve problem that…
- Conditions
- Pain, Peripheral Neuropathy, Tingling
- Trial name
- NCT02722434
- Testing
- Laboratory Biomarker Analysis, MC5-A Scrambler Therapy, Questionnaire Administration
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Mayo Clinic
Diabetes Mellitus, Diabetes Complications
Diabetes Complications and Hearing Loss
Observation study, shows the relation between diabetes, its neurological and optical complication and hearing loss, by asking participants questions about there age,BMI,job,the history of any cataract,diabetes retinopathy or…
- Conditions
- Diabetes Mellitus, Diabetes Complications, Hearing Loss
- Trial name
- NCT06190938
- Where
- Syria
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Syrian Private University
Vision Impairment
Providing Access to the Visual Environment
Providing Access to the Visual Environment is a pediatric low vision grant which has the ability to provide comprehensive, interdisciplinary low vision rehabilitation services to every child in Tennessee with a vision impairment.
- Trial name
- NCT00341744
- Where
- United States
- Volunteers
- 795 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Aging, Age Related Hearing Loss
Cognitive Training to Improve Mobility in Middle-aged and Older Adults
The proposed study is designed to evaluate the effect of at-home executive function training on cognition and mobility in older adults with age-related hearing loss (ARHL), older adults with normal hearing, and middle-aged adults.
- Trial name
- HnW (NCT05418998)
- Testing
- Executive function (EF) training
- Where
- Canada
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Concordia University, Montreal
Hearing Loss, Cochlear Trauma
SPI-1005 in Adults Receiving Cochlear Implant
The goal of this clinical trial is to learn about the effects of drug SPI-1005 in adults receiving a cochlear implant with a long electrode array (FLEX26 or greater) from MED-EL Cochlear Implant Systems into one ear.
- Trial name
- NCT06340633
- Testing
- Ebselen
- Where
- 6 sites in United States
- Volunteers
- 40 people
- Sponsor
- Sound Pharmaceuticals, Incorporated
Healthy
Changes in Sensory Perception During Hypnotic Relaxation
Changes in sensory thresholds and pain thresholds will be measured with quantitative sensory testing (QST) before and during hypnotic relaxation in healthy volunteers. Hypnotic susceptibility will be assessed before QST.
- Trial name
- NCT02261155
- Testing
- Hypnosis
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Ludwig-Maximilians - University of Munich
Vision, Low
Spectacles for Patients With Down Syndrome
This study tests the hypothesis that objectively derived spectacle prescriptions based on wavefront aberration measurements of the eyes of individuals with Down syndrome can provide an improvement in visual acuity over that…
- Trial name
- NCT03367793
- Testing
- Spectacles - Clinically Derived, Spectacles - Metric Technique #1 Derived, Spectacles - Metric Technique #2 Derived
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Houston
Chemotherapy Side Effects, Taste, Altered
Taste Alterations Study
The main questions it aims to answer are: 1. Does completing a standard assessment increase the detection of chemotherapy induced taste changes compared with usual care (no assessment)? What TA are experienced? Are there any…
- Trial name
- TAS (NCT06669416)
- Testing
- Taste Alteration Self-Assessment, Taste Alternation Self-Management
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Wake Forest University Health Sciences
Hearing Loss
ICF in Cochlear Implant Users
The current project proposes a multi-center prospective follow-up cohort study aiming to realize an international framework to classify human functioning and disability in Cochlear Implant (CI) recipients using a standardized ICF…
- Trial name
- NCT04611555
- Where
- 5 sites in Australia, Belgium and 3 more
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Neovascular Age-related Macular Degeneration
An Extension Study Assessing the Efficacy and Safety of Brolucizumab in a Treat-to-Control Regimen in Patients With Neovascular Age-related Macular Degeneration Who Have Completed the CRTH258A2303 (TALON) Study
The purpose of this extension study was to evaluate the efficacy and safety of brolucizumab used in a Treat-to-Control-regimen for treatment of patients with neovascular age-related macular degeneration who have completed the…
- Trial name
- TALON Ext (NCT04597632)
- Testing
- brolucizumab
- Where
- 60 sites in United States, Australia and 14 more
- Volunteers
- 248 people
- Sponsor
- Novartis Pharmaceuticals
Hearing Loss, Adult-Onset, Dementia
Hearing Loss and Brain Health Study
Hearing loss is a prevalent and modifiable risk factor for cognitive decline and dementia in older adults, yet access to hearing care remains limited.
- Trial name
- NCT07288463
- Testing
- Over-The-Counter (OTC) hearing aid
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Southern California
Hearing Loss, Noise-Induced
Noise Exposure and Near-Infrared Light
The primary objective of this work is to determine the effect noise has on the auditory system (both auditory health and performance) and also the degree to which the effect of pre-noise therapy such as Near Infrared (NIR) light…
- Trial name
- NCT03834714
- Testing
- Near Infrared Light, Noise Stimulus
- Where
- 3 sites in United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Miami
Amblyopia
Study of Binocular Computer Activities for Treatment of Amblyopia
The purpose of the study is to compare the effectiveness of 1 hour/day of binocular game play 7 days per week with 2 hours/day patching 7 days per week in children 5 to <17
- Trial name
- ATS18 (NCT02200211)
- Testing
- iPad®, Patching 2 hours per day, 7 days per week
- Where
- 2 sites in United States
- Volunteers
- 485 people
- Sponsor
- Jaeb Center for Health Research
Blindness
Emergency Egress and Information System for Persons With Vision Loss
The purpose of the research project is to develop and evaluate an emergency egress system for persons with visual impairment, which would use existing lighted exit signage to provide egress information at a distance of up to 100…
- Trial name
- NCT00262509
- Testing
- Egress Badge
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Depression, Anxiety
Pilot Test of a Cultural Intervention to Enhance Alaska Native Students' Behavioral Health
This project aims to enhance AN university students' behavioral health by supporting their cultural identity development. While the connection between cultural identity and behavioral health is becoming clearer, comparably less…
- Conditions
- Depression, Anxiety, Suicidal Ideation, Substance Use
- Trial name
- NCT04561544
- Testing
- Knowing Who You Are (Becoming): Cultural Identity Intervention
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Alaska Anchorage
Usher Syndrome, Type 1B
Study of Subretinally Injected AAVB-081 in Patients With Usher Syndrome Type IB (USH1B) Retinitis Pigmentosa
The purpose of the 081-101 study is to evaluate the safety and tolerability of a single subretinal injection of AAVB-081 in USH1B patients with retinitis pigmentosa due to a mutation in the MYO7A gene.
- Trial name
- NCT06591793
- Testing
- AAVB-081
- Where
- 3 sites in Italy, United Kingdom
- Volunteers
- 15 people
- Sponsor
- AAVantgarde Bio Srl
Irritable Bowel Syndrome
Effect of a Cannabinoid Agonist on Colonic Sensory Functions in Patients With Irritable Bowel Syndrome
Irritable bowel syndrome (IBS) affects about 15% of the U.S. population. There are still no effective and safe medications approved for the treatment of abdominal pain associated with bowel symptoms in IBS.
- Trial name
- NCT01786109
- Testing
- Dronabinol
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Michael Camilleri
Spinal Needle Diameter and Design, Click Feeling
The Effect of Different Types of Spinal Needles on the Success of the Procedure
The effects of spinal needles with different tip designs on the success of the application and the number of attempts required to get the spinal click feeling.
- Trial name
- NCT05704816
- Testing
- Spinal anesthesia application
- Where
- Turkey (Türkiye)
- Volunteers
- 213 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Healthy Volunteers
Functional Significance of Complexity Measures in the Sensory-motor Behavior
The main objective of this study is to compare between groups the level of complexity of the estimated sensorimotor performance through multi-fractal (minmaxMF-DFA) exponents.
- Trial name
- NEURO COMP (NCT02610647)
- Testing
- Wrist anesthesia, Blinding mask, Anti-noise helmet
- Where
- 3 sites in France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Macular Degeneration
A Long-Term Monitoring Study of the IMT-002 Patients
This is a 5-year study of patients implanted with the Implantable Miniature Telescope (IMT by Dr. Isaac Lipshitz) under Protocol IMT-002.
- Trial name
- NCT00976235
- Testing
- IMT - Implantable Miniature Telescope
- Where
- 28 sites in United States
- Volunteers
- 129 people
- Sponsor
- VisionCare, Inc.
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