Clinical trials: Sensory Function
Hearing Loss, Bilateral Sensorineural, Progressive, Hearing Loss, Bilateral (Causes Other Than Tumors)
Hearing Screening in Adults Over 50 Years Old
The goal of this single-arm quasi-experimental study is to evaluate the feasibility, effectiveness, and management of three different hearing screening methods in adults aged 50 years and older in the Czech Republic.
- Conditions
- Hearing Loss, Bilateral Sensorineural, Progressive, Hearing Loss, Bilateral (Causes Other Than Tumors), Hearing Loss, Bilateral or Unilateral, Presbyacusis
- Trial name
- HSA50+ (NCT06894927)
- Testing
- Screening HHIA questionnaire, Whispered voice test, Screening pure tone audiometry
- Where
- 2 sites in Czechia
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- University Hospital Hradec Kralove
Type 2 Diabetes Mellitus
Effects Of Resistive Exercise or Proprioceptive Exercise Training Among Patients With Type 2 Diabetes Mellitus
The aim of the study is to investigate proprioceptive exercises training combined with aerobic exercises and resistive exercises training combined with aerobic exercises on dynamic balance and superficial sense.
- Trial name
- NCT03363386
- Testing
- Proprioceptive Exercises, Resistive Exercises, Aerobic Exercise
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Yeditepe University
CBD Stone
Re-use of Ambu aScope During Exploration of the Common Bile Duct for Stones in Low-Resource Settings- a Retrospective Study
Various methods confirm stone clearance during surgical exploration of bile duct, but choledochoscopy is considered the most effective. However, choledochoscopes are expensive and often unavailable in low-resource settings.
- Trial name
- NCT07285447
- Testing
- Ambu aScope for visualization of biliary tree during exploration of CBD for stone
- Where
- Nepal
- Volunteers
- 75 people
- Sponsor
- B.P. Koirala Institute of Health Sciences
Olfactory Disorder
Anosmia Rehabilitation in Patients Post Coronavirus Disease (COVID 19)
The study will be a randomized controlled trial, involving patients with hyposmia/anosmia of onset immediately after an upper respiratory viral illness, assigned to three distinct study arms.
- Trial name
- NCT04374474
- Testing
- Olfactory retraining, corticosteroid nasal irrigation, smell household Items
- Where
- Canada
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Tinnitus
Efficacy of Treatment for Tinnitus
Tinnitus is the acoustic perception of sound without any physical source. It is estimated that 15-21% of adults develop a Tinnitus, which can cause serious distress and debilitation in all aspects of daily life of the affected.
- Trial name
- NCT02632058
- Testing
- Cognitive Behavioral Therapy
- Volunteers
- 500 people
- Sponsor
- Psychiatrische Dienste Graubuenden
Tinnitus
rTMS To The Dorsolateral Prefrontal Cortex For Patients With Subjective Idiopathic Tinnitus. A Pilot Study
The neurological basis of tinnitus is uncertain when there is no evidence of damage to the peripheral auditory system. However, neuroimaging studies of tinnitus patients show hyperactivity in several cortical regions, especially…
- Trial name
- NCT00886938
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS), pilot study
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Washington University School of Medicine
Stage 0 Nasopharyngeal Carcinoma, Stage 0 Paranasal Sinus Cancer
Olfactory Training in Improving Sense of Smell After Radiation Therapy in Patients With Paranasal Sinus or Nasopharyngeal Cancer
This randomized phase I trial studies how well olfactory training works in improving sense of smell after radiation therapy in patients with paranasal sinus or nasopharyngeal cancer.
- Conditions
- Stage 0 Nasopharyngeal Carcinoma, Stage 0 Paranasal Sinus Cancer, Stage I Nasopharyngeal Carcinoma, Stage I Paranasal Sinus Cancer
- Trial name
- NCT03049358
- Testing
- Physiologic Testing, Quality-of-Life Assessment, Therapeutic Procedure
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Stanford University
Parkinson Disease, Orthostatic Hypotension
Cardiovascular Effects of Exercise in Patients With Parkinson's Disease
Abnormalities in the regulation of cardiovascular system due to autonomic nervous system (ANS) dysfunction may lead to a sudden decline in blood pressure (BP) upon standing, sitting or performing activities/exercises in patients…
- Trial name
- NCT03343574
- Testing
- Abdominal Strengthening Exercise
- Where
- Canada
- Volunteers
- 300 people
- Sponsor
- Faizan Ahmed
Dizziness and Vertigo
Acupuncture for Dizziness and Vertigo in Emergency Department
This study was conducted at China Medical University Hospital, Taiwan, between January 2019 and December 2023, with 345 patients diagnosed with dizziness and vertigo (ICD-10 codes R42 and H81).
- Trial name
- NCT06873217
- Testing
- Acupuncture
- Where
- Taiwan
- Volunteers
- 345 people
- Sponsor
- China Medical University Hospital
Olfaction Disorders
Is Pentoxifylline Able to Improve Olfactory Sensitivity?
Signal processing in the olfactory neuron could be influenced by inhibition of enzymes like phosphodiesterase. Pentoxifylline is a unspecific phosphodiesterase inhibitor.
- Trial name
- NCT00660868
- Testing
- Pentoxifylline retard 400mg
- Where
- Germany
- Volunteers
- 7 people
- Sponsor
- Technische Universität Dresden
Imaging of Bony Structures of the Head (Various Conditions), Hearing Loss
MRI-based Synthetic CT Images of the Head and Neck
In case of surgical procedures in the head and neck region, MRI in combination with CT of the bone is often the standard modality to visualise bony landmarks for planning, navigation and risk assessment.
- Conditions
- Imaging of Bony Structures of the Head (Various Conditions), Hearing Loss, Cholesteatoma, Sinusitis
- Trial name
- NCT06016335
- Testing
- CT scan, MRI scan, Synthetic CT scan
- Where
- Netherlands
- Volunteers
- 80 people
- Sponsor
- Amsterdam UMC, location VUmc
Hearing Impaired
Brain and Cognitive Changes After Reasoning or Physical Training in Cognitively Normal Seniors
Seniors 65 years of age and older represent one of the fastest growing segments of society with the population doubling within the next 25 years with dramatic rates of mental decline, costing society billions of dollars each…
- Trial name
- NCT00977418
- Testing
- SMART- Strategic Memory and Reasoning Training, Physical Exercise
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Dallas
Vertigo, Dizziness
Translation of Dizziness Handicap Inventory Scale Into Local Languages of Pakistan
The aim of the present study is to translate the Dizziness Handicap Inventory Scale into Urdu, Pashto, Punjabi, Sindhi and Balochi languages.
- Trial name
- NCT04849078
- Where
- Pakistan
- Volunteers
- 1,000 people
- Sponsor
- Riphah International University
Retinitis Pigmentosa (RP)
Retrospective Natural History Study of Retinitis Pigmentosa
This is natural history study of rods and cones degenerations in patients with Retinitis Pigmentosa (RP) caused by pathogenic mutations in RHO, PDE6A or PDE6B gene mutations.
- Trial name
- PHENOROD1 (NCT03975543)
- Where
- France
- Volunteers
- 113 people
- Sponsor
- SparingVision
Anesthesia, Anesthesia, Local
A Study in Healthy Male Volunteers to Investigate the Safety and Tolerability of a Single Dose of Neosaxitoxin Alone and in Combination With Bupivacaine (With and Without Epinephrine) for Brachial Plexus Blockade
Neosaxitoxin is a new compound that is in clinical development as local anesthetic for surgical anesthesia and postoperative analgesia.
- Conditions
- Anesthesia, Anesthesia, Local, Analgesia
- Trial name
- NCT03399435
- Testing
- Neosaxitoxin combined with bupivacaine low and epinephrine (T1), Bupivacaine low combined with epinephrine (C1), Bupivacaine high combined with epinephrine (C2)
- Where
- Netherlands
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- Grünenthal GmbH
Visual Impairments, Low Vision Digital Assistance
Effectiveness of a Multi-disciplinary Vision Rehabilitation Programme in Improving the Overall Quality of Life of Visually Impaired Adults
This trial compares multidisciplinary vision rehabilitation and vision rehabilitation services to determine which service works better at improving overall quality of life for adults with visual impairment.
- Conditions
- Visual Impairments, Low Vision Digital Assistance, Adults
- Trial name
- NCT07827040
- Testing
- Multidisciplinary vision rehabilitaion, Vision rehabilitation incorporating low vision training only
- Where
- Hong Kong
- Volunteers
- 1,000 people
- Sponsor
- The Hong Kong Polytechnic University
Sensory Deficit
Functional Assessment of a Vibration Feedback on the Gripping Pressure in the Territory of the Median Nerve
The objective of this study is to investigate the effect of vibration feedback on the gripping pressure in the territory of the median nerve.
- Trial name
- TEXIGLOVE (NCT01691443)
- Testing
- pressure sensor and wrist shaker, not marked CE, developped by Texisense
- Where
- France
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Plantar Sensation, Balance; Distorted
Plantar Sensation, Balance, Risk of Falling and Gait in Patients With Schizophrenia
Cerebellar vermis anomalies are present in schizophrenic individuals. This condition leads to postural balance problems. Foot and ankle complex have a special role for maintaining balance.
- Conditions
- Plantar Sensation, Balance; Distorted, Fall, Gait Disorders, Neurologic
- Trial name
- NCT03476408
- Testing
- Correlation / Observational
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Mechanical Neck Pain
Effect of Proprioceptive Training Using Head Mounted Laser in Chronic Mechanical Neck Pain
The purpose of this study is to compare the effect of conventional physical therapy with and without cervical proprioceptive training using head-mounted laser system on cervical joint position sense error, pain, cervical range of…
- Trial name
- NCT06034223
- Testing
- Proprioceptive training using head mounted laser, Conventional Physical therpay
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Shifa Tameer-e-Millat University
Meniere's Disease, Ménière's Disease
SPI-1005 for the Treatment of Meniere's Disease (Open Label)
Study of the safety of open-label SPI-1005 400 mg BID treatment in adults with Meniere's Disease (MD) for 6 or 12 months to support chronic or chronic intermittent use.
- Trial name
- NCT06859788
- Testing
- Ebselen
- Where
- 9 sites in United States
- Volunteers
- 200 people
- Sponsor
- Sound Pharmaceuticals, Incorporated
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