Clinical trials: Sentinel Nodes
Breast Cancer Lymphedemas
Bioelectrical Impedance Utilization and Dietary Intake Relation in the Breast Cancer Related Lymphedema
The purpose of this study was to investigate the clinical role of bioelectrical impedance analysis (BIA) and the relationship between the occurrence of breast cancer related lymphedema (BCRL) and dietary factors in breast cancer…
- Trial name
- NCT03391206
- Testing
- Inbody 720
- Where
- South Korea
- Volunteers
- 228 people
- Sponsor
- Severance Hospital
Colorectal Cancer, Angiogenesis
Micrometastases and Angiogenesis in Colon Cancer. Prognostic Value of VEGF.
According to current clinical guidelines adjuvant treatment in colon cancer is not recommended in patients with stage I and IIA, and in patients with high risk factors (IIB) adjuvant treatment has not shown a clear benefit in…
- Trial name
- VEGF-GC (NCT04145505)
- Testing
- COLORECTAL CANCER SURGERY
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Cervical Cancer
Sentinel Concept in Early Stage Cervical Cancer
Aim of present study is to inspect, if the removal alone of sentinel lymph nodes in women with early Cervix Carcinoma lead to, at equal length, overall survival like entire systematic dissection of lymph node and at the same time…
- Trial name
- NCT01157962
- Testing
- Lymphadenectomy in cervical cancer
- Where
- Germany
- Volunteers
- 1,600 people
- Sponsor
- Charite University, Berlin, Germany
Breast Cancer
Clinical Trial Comparing Outcomes of Breast Conserving Operations With Classic v High-frequency Electrocoagulation
The aim of this study is to assess the outcomes of breast conserving therapy operation depending on the type of surgical tool used: classic electrocoagulation with higher operative temperatures and high frequency…
- Trial name
- NCT01216254
- Testing
- classic v high-frequency electrocoagulation
- Where
- Poland
- Volunteers
- 150 people
- Sponsor
- Medical University of Gdansk
Breast Cancer
The T-REX Trial: Tailored Regional External Beam Radiotherapy in Clinically Node-negative Breast Cancer Patients With 1-2 Sentinel Node Macrometastases.
T-REX is a randomized multicenter, non-inferiority trial. Aim: To evaluate whether regional radiotherapy may safely be omitted in clinically node negative breast cancer patients with one or two sentinel node macrometastases and…
- Trial name
- T-REX (NCT05634889)
- Testing
- De-escalation
- Where
- 30 sites in Finland, Norway and 1 more
- Volunteers
- 1,350 people
- Sponsor
- Region Skane
Breast Cancer, Locally Recurrent Breast Cancer
Photo-medicine-Guided Dual Approach for Reoperation of Sentinel Lymph Nodes in Locally Recurrent Breast Cancer Patients
Sentinel lymph node biopsy (SLNB) is essential for staging and treatment planning in early breast cancer patients. As a less invasive procedure, it has replaced axillary lymph node dissection (ALND) by reducing complications and…
- Conditions
- Breast Cancer, Locally Recurrent Breast Cancer, Sentinel Lymph Node Biopsy (SLNB), Reoperation
- Trial name
- NCT06780748
- Testing
- Identification rate of sentinel lymph node
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Cancer Center, Korea
Breast Cancer, Sentinel Lymph Node
Use of Superparamagnetic Iron Oxide (SPIO) in Sentinel Lymph Node Detection for Breast Cancer
Sentinel lymph node biopsy is mandatory during breast cancer operation for disease staging and treatment. The localization of sentinel lymph node is by the injection of radioisotope and blue dye, which is the gold standard.
- Trial name
- NCT05288686
- Testing
- sentinel lymph node biopsy procedure
- Where
- Hong Kong
- Volunteers
- 282 people
- Sponsor
- The University of Hong Kong
Breast Cancer, Sentinel Lymph Node
Tumor-Targeted-NIR-II Fluorescent Molecular Probes for the Identification of Breast Cancer Tissue and SLN Metastatic Status
Accurate evaluation of tumor boundaries in breast-conserving surgery is closely associated with reducing the second operation of patients.
- Conditions
- Breast Cancer, Sentinel Lymph Node, Metastases, Margin Assessment
- Trial name
- NIR-II (NCT06713161)
- Testing
- NIR-II Probe(i.e ICG-POL6326) incubation solution
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Yunnan Cancer Hospital
Early Gastric Cancer
Feasibility Study of Sentinel Navigation Surgery in Early Gastric Cancer Using Fluorescence (SENORITA4)
SENORITA 1 trial showed laparoscopic sentinel lymph node biopsy and stomach preserving surgery in early gastric cancer can increase the quality of life. (Ryu KW et al.
- Trial name
- NCT05978882
- Testing
- Laparoscopic sentinel navigation surgery using fluorescence
- Where
- 7 sites in South Korea
- Volunteers
- 203 people
- Sponsor
- National Cancer Center, Korea
Squamous Cell Carcinoma, Nonmelanoma Skin Cancer
Sentinel Lymph Node Biopsy for Cutaneous Squamous Cell Carcinoma of the Head and Neck
The purpose of this study is to research if a type of biopsy known as sentinel lymph node biopsy (SLNB) can help in determining the rate of tumor deposits that are hard to detect and identify in node-negative cutaneous squamous…
- Conditions
- Squamous Cell Carcinoma, Nonmelanoma Skin Cancer, Cutaneous Squamous Cell Carcinoma
- Trial name
- NCT05108090
- Testing
- sentinel lymph node biopsy (SLNB)
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- Indiana University
Squamous Cell Carcinoma of the Anus
Study to Determine the Feasibility of Sentinel Node Biopsy in Patients With Anal Cancer
The purpose of this study is assess the technical and operational feasibility of a specialised biopsy technique, sentinel lymph node biopsy (SLNB), in patients with anal cancer.
- Trial name
- R-SeNSAR (NCT02162641)
- Testing
- Sentinel lymph node biopsy
- Sponsor
- The Christie NHS Foundation Trust
Endometrial Cancer, Cervical Cancer
Implementation of Surgical Safety and Intraoperative Metastasis Identification Through Deep Learning: Multicentric Video Collection for Minimally Invasive Sentinel Lymph Node Dissection in Uterine Malignancies
The loco-regional metastatic or non-metastatic status of lymph nodes (LN) is critical for the therapeutic management of most cancer patients.
- Conditions
- Endometrial Cancer, Cervical Cancer, Deep Learning, Artificial Intelligence
- Trial name
- LYSE (NCT06619002)
- Testing
- Sentinel lymph node sampling
- Where
- 2 sites in Italy
- Volunteers
- 100 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Breast Cancer
Sentinel Lymph Node Biopsy Versus no Axillary Surgery in Early Breast Cancer
The VENUS trial is a prospective, multicenter, noninferiority, randomized, controlled clinical trial that compares sentinel lymph node biopsy versus no axillary surgery in women with early breast cancer (tumor <5cm) and…
- Trial name
- VENUS (NCT05315154)
- Testing
- No axillary surgery, SLNB
- Where
- 18 sites in Brazil
- Volunteers
- 800 people
- Sponsor
- University of Campinas, Brazil
Lymphedema, Breast Cancer
Arm Circumference Measurement With or Without Bioimpedance Spectroscopy in Finding Lymphedema Early in Patients With Stage I-III Breast Cancer
This randomized pilot clinical trial studies arm circumference measurement with or without bioimpedance spectroscopy in finding extra lymph node fluid build up in the arm (lymphedema) early in patients with stage I-III breast…
- Trial name
- NCT03648983
- Testing
- arm circumference measurement, Bioimpedance spectroscopy
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Albert Einstein College of Medicine
Breast Cancer, Sentinel Lymph Node
Artificial Intelligence Analysis of Fluorescence Image to Intraoperatively Detect Metastatic Sentinel Lymph Node.
The purpose of this study is to analysis the fluorescence image of the breast sentinel lymph node (SLN) using Indocyanine green (ICG).
- Trial name
- NCT05623280
- Testing
- Indocyanine green
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Xiang'an Hospital of Xiamen University
Sentinel Lymph Node
Sentinel Lymph Node Biopsy After Neoadjuvant Chemotherapy in Initially Node Positive Breast Cancer Patients, Could it Omit Axillary Dissection ?
The aim of this study is to determine the accuracy and safety of SLNB after neoadjuvant chemotherapy.
- Trial name
- NCT06130241
- Testing
- sentinle lymphnode biopsy
- Volunteers
- 30 people
- Sponsor
- Assiut University
Endometrial Cancer
Comparison of Nodal Staging in Endometrial Cancer
This study aims to estimate the recurrence-free survival rates in women with endometrial cancer treated with selective versus sentinel node surgical staging.
- Trial name
- NCT04970368
- Testing
- Sentinel node procedure, Selective staging
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Frederick R. Ueland, M.D.
Sentinel Lymph Node, Head and Neck Squamous Cell Carcinoma
Peritumoral Microbubbles and CEUS for SLN Detection and Biopsy in HNSCC
Head and neck squamous cell carcinoma is the sixth most common malignant tumor in the world. Cervical lymph node metastasis is frequently encounted on the date of diagnosis.
- Trial name
- NCT05437380
- Testing
- peritumoral microbubbles and contrast-enhanced ultrasonography
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Endometrial Endometrioid Adenocarcinoma
Evaluation of the Efficacy for Sentinel Lymph Node Policy in Intermediate-risk Endometrial Carcinomas
To evaluate the efficacy of sentinel lymph node policy in patients with intermediate-risk endometrial carcinomas
- Trial name
- NCT03677024
- Testing
- SLN arm
- Where
- China
- Sponsor
- Fudan University
Colon Cancer
The Significance of Sentinel Node Analysis in Colon Cancer
This study is for the patient with colon cancer, who is going to have colon cancer surgery. The purpose of this research study is to examine a specific lymph node, called the sentinel node.
- Trial name
- NCT00419978
- Testing
- Colectomy
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Legacy Health System