Clinical trials: Sepsis, completed
Endotoxemia, Diet, Healthy
Cereals and Intestinal Function
The aim of the present study is to determine the effect of dietary fiber on intestinal function in healthy subjects.
- Trial name
- NCT04019457
- Testing
- Dietary intervention
- Where
- Austria
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Vienna
Bacterial Infections
Evaluation of the Artificial Intelligence-based Prescription Support Software iAST® for the Choice of Empirical and Semi-targeted Antibiotic Treatment
Inadequate treatment of infections frequently leads to complications that cause new visits to the doctor, lengthen hospital stays and can lead to sepsis, even causing the death of affected patients.
- Trial name
- EVIAST (NCT06174519)
- Testing
- Medical device simulation
- Where
- Spain
- Volunteers
- 325 people
- Sponsor
- Pragmatech AI Solutions
Sepsis
Procalcitonin-Guided Antimicrobial Discontinuation
The current study aims to validate the diagnostic use of PCT assessing its capability to individualize and shorten the duration of antibiotic therapy in critically ill patients with suspected or confirmed sepsis.
- Trial name
- NCT00250666
- Testing
- PCT measurement
- Where
- Switzerland
- Volunteers
- 70 people
- Sponsor
- University Hospital, Geneva
Sepsis, Septic Shock
Evaluation of Candidate Biomarkers to Predict Disease Severity and Acute Kidney Injury in Sepsis Patients
Investigators predict that the information that can be obtained in terms of renal functions before clinical development in sepsis patients can be valuable in terms of guiding treatment algorithms, planning renal replacement…
- Conditions
- Sepsis, Septic Shock, Acute Kidney Injury
- Trial name
- NCT05310812
- Testing
- Biochemical evaluation.
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Istanbul University
Infection, Sepsis
Viscoelastic Coagulation for Early Sepsis Detection
The goal of this observational study is to investigate whether selected variables of coagulation measured by Viscoelastic Coagulation Monitoring (VCM) can serve as early predictors of progression to sepsis in adult patients…
- Trial name
- VISION (NCT07073456)
- Testing
- Viscoelastic Coagulation Monitoring measurements
- Where
- 2 sites in Greece
- Volunteers
- 147 people
- Sponsor
- Hellenic Institute for the Study of Sepsis
Septic Shock, Vasoplegia
Evaluating in Cirrhotics With Refractory Vasoplegia the Effect of Methylene Blue
Mortality rates associated septic shock remains unacceptably high, around 20-50%, with refractory hypotension in half of these patients.
- Conditions
- Septic Shock, Vasoplegia, Cirrhosis, Liver, Refractory Shock
- Trial name
- CRuMBS (NCT03120637)
- Testing
- Methylene Blue
- Where
- India
- Volunteers
- 111 people
- Sponsor
- Institute of Liver and Biliary Sciences, India
Colorectal Cancer
Comparison of Probiotic Effects on the Outcomes of Patients After Colorectal Cancer Surgery
This clinical trial aims to compare the effects of administering Lactobacillus casei Shirota probiotics with Lactobacillus acidophilus on the outcomes of patients after colorectal cancer surgery.
- Trial name
- NCT07144475
- Testing
- Lactobacillus casei Shirota, Lactobacillus acidophilus
- Where
- Indonesia
- Volunteers
- 90 people
- Sponsor
- Dharmais National Cancer Center Hospital
Ventilator Associated Pneumonia ( VAP), Sepsis
High Dose of Vitamin C on Mechanically Ventilated Septic Patients in Intensive Care Unit
Prospective, Randomized clinical trial study will be carried out in intensive care unit in Ain Shams University Hospitals on 40 forty septic patients admitted to ICU and mechanically ventilated.
- Trial name
- NCT04029675
- Testing
- Vitamin C
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ain Shams University
Sepsis, Septic Shock
DIAGNOSis of Infection in Emergency Department
Septic pathology is an extremely frequent reason for consultation in our emergency services, with an annual incidence of severe forms between 50 to 95 cases per 100,000 inhabitants and a constant increase estimated at 9% per…
- Conditions
- Sepsis, Septic Shock, Sepsis, Severe, Infection
- Trial name
- DIAGNOSED (NCT03708796)
- Testing
- SIRS, qSOFA, NEWS, RETTS scores evaluation
- Where
- 7 sites in France
- Volunteers
- 759 people
- Sponsor
- Association pour la Formation l'Enseignement et la Recherche du Service de l'Accueil des Urgences
Bacteremia
Epidemiology of Bacteremia at Two Tertiary ICUs in Switzerland
The objectives of the retrospective cohort study is to describe the actual current practice of antibiotic treatment duration for bloodstream infections in critically ill patients at two tertiary hospitals (ICU Inselspital Bern…
- Trial name
- NCT05236283
- Testing
- Blood Culture
- Where
- Switzerland
- Volunteers
- 395 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Sepsis, Respiratory Physiological Phenomena
Respiratory Variations for Predicting Fluid Responsiveness
Hypovolemia and acute circulatory failure affects more than 60% of patients hospitalized in intensive care or resuscitation. The volume expansion (VE) by fluid replacement therapy is the first treatment improve circulatory…
- Conditions
- Sepsis, Respiratory Physiological Phenomena, Circulatory Failure
- Trial name
- ReVaPreF (NCT03066362)
- Testing
- Echocardiography-Doppler
- Where
- France
- Volunteers
- 90 people
- Sponsor
- University Hospital, Lille
Sepsis, Septic Shock
Clearance of Antibacterial Agents During Hemoperfusion in Patients With Sepsis
One of the significants health problems in the world is sepsis, with the number of cases reaching 20-30 million per year, according to the WHO.
- Trial name
- NCT06602245
- Where
- 4 sites in Russia
- Volunteers
- 30 people
- Sponsor
- Efferon JSC
Severe Sepsis, Organ Dysfunction Syndrome
Effect of Docosahexaenoic Acid on the Inflammatory Response and Clinical Outcomes From Surgical Patients
The purpose of this study is to evaluate if enteral docosahexaenoic acid (DHA) administration attenuates the inflammatory cytokines and improve clinical outcomes in neonates who underwent cardiovascular surgery
- Trial name
- DHA-IRCO (NCT01049529)
- Testing
- Docosahexaenoic acid
- Where
- Mexico
- Volunteers
- 55 people
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Respiration, Artificial
Study of the Combined Influence of Sepsis and Mechanical Ventilation on the Human Diaphragm
The aim of this study is to study the combined impact of mechanical ventilation and sepsis on the human diaphragm in order to establish the neutral, protective or destructive character of mechanical ventilation by studying the…
- Trial name
- SEPTIC (NCT03371602)
- Testing
- surgery, multi-organ sampling
- Where
- France
- Volunteers
- 33 people
- Sponsor
- Hospices Civils de Lyon
Sepsis
A Simple Clinical Tool to Help Assess Patient Volume (Fluid) Status
Patients may have actual or relative intravascular volume depletion in a number of different disease states, particularly with sepsis syndrome.
- Trial name
- NCT00599794
- Where
- 2 sites in United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Candidemia
Detecting Infections Rapidly and Easily for Candidemia Trial - Part 2 (direcT2 Study)
The purpose of this study is to validate clinical performance (i.e. estimated sensitivity and specificity) of the T2 Candida test on the T2 DX Instrument compared to blood culture results and/or known Candida positive status of…
- Trial name
- direcT2 (NCT01752166)
- Where
- 8 sites in United States
- Volunteers
- 1,500 people
- Sponsor
- T2 Biosystems
Severe Sepsis, Septic Shock
The Role of Dysfunctional HDL in Severe Sepsis
Severe sepsis results in over 300,000 Emergency Department (ED) visits and 215,000 deaths annually in the US. Currently there are no effective drug therapies for sepsis.
- Conditions
- Severe Sepsis, Septic Shock, Sepsis
- Trial name
- NCT02370186
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- University of Florida
Vascular Access Complication
Vascular Access in Hematological Patients - PICC Versus CVC
The use of peripherally inserted central catheters (PICCs) represents a major advance for hematological patients, enabling the effective delivery of chemotherapy and/or blood products particularly for prolonged infusions or in…
- Trial name
- NCT02405728
- Testing
- Centrally inserted central catheters (CICCs), Peripherally inserted central catheters (PICCs)
- Where
- Italy
- Volunteers
- 88 people
- Sponsor
- Federico II University
Sepsis
Effect of Montelukast Versus Co Enzyme in Sepsis
Sepsis is a leading cause of morbidity and mortality in intensive care units. Sepsis is a life-threatening organ dysfunction linked to a dysregulated host response to infection.
- Trial name
- NCT05293132
- Testing
- Montelukast Sodium 10 mg, Co-Enzyme Q10, Standard Treatment
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Ain Shams University
Cardiac Output, LIDCO Rapid, Septic Shock
Validation of Uncalibrated Cardiac Output Measurement With LiDCOrapid in the Resuscitation of Critically Ill Patients With Septic Shock: A Prospective Cross-sectional Study.
Transthoracic echocardiography (TTE) has been used as a reference technique for CO measurement and its accuracy has been adequate for many clinical uses. TTE is painless, safe and non-invasive.
- Trial name
- NCT04705493
- Testing
- fluid resuscitation with crystalloid
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.