Clinical trials: Sepsis, completed
Cardiovascular Diseases, Acute Coronary Syndrome
The IndONEsia ICCU Registry: a Multicenter Cohort of Intensive Cardiovascular Care Units Patients in Indonesia
Patients in the Intensive Cardiovascular Care Unit (ICCU) often present with cardiovascular disease (CVD) issues accompanied by various non-cardiovascular conditions.
- Conditions
- Cardiovascular Diseases, Acute Coronary Syndrome, Heart Failure, Heart Disease, Coronary
- Trial name
- NCT06265714
- Where
- 9 sites in Indonesia
- Volunteers
- 12,950 people
- Sponsor
- Universitas Indonesia
Sepsis, Severe Sepsis
Protocolized Care for Early Septic Shock
The ProCESS study is large, 5-year, multicenter study of alternative resuscitation strategies for septic shock. The study hypothesizes that there are "golden hours" in the initial management of septic shock where prompt…
- Conditions
- Sepsis, Severe Sepsis, Septic Shock
- Trial name
- ProCESS (NCT00510835)
- Testing
- Early Goal Directed Therapy (EGDT), Protocolized Standard Care (PSC), Usual Care (UC)
- Where
- 31 sites in United States
- Volunteers
- 1,351 people
- Sponsor
- University of Pittsburgh
Sepsis
Vitamin C, Thiamine, and Steroids in Sepsis
The VItamin C, Thiamine And Steroids in Sepsis (VICTAS) Study is a double-blind, placebo-controlled, adaptive randomized clinical trial designed to investigate the efficacy of the combined use of vitamin C, thiamine and…
- Trial name
- VICTAS (NCT03509350)
- Testing
- Vitamin C, Thiamine, Hydrocortisone
- Where
- 43 sites in United States
- Volunteers
- 501 people
- Sponsor
- Emory University
Sepsis
Pasteurization of Mother's Own Milk for Preterm Infants
We hypothesize that short term infection-related benefits of human milk feeding are decreased by the process of pasteurization. Primary objective of the study is to compare the incidence of late-onset sepsis in very low birth…
- Trial name
- NCT01580826
- Testing
- pasteurization of mother's own milk
- Where
- Belgium
- Volunteers
- 303 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Septic Shock
Investigating FE 202158 as Potential Primary Treatment in Patients With Early Septic Shock
The purpose of this trial is to investigate the potential of FE 202158 as a treatment which can stabilize blood pressure for treatment of patients in early septic shock.
- Trial name
- NCT01612676
- Testing
- FE 202158
- Where
- 4 sites in Belgium, Denmark
- Volunteers
- 31 people
- Sponsor
- Ferring Pharmaceuticals
Neurological Diseases, Heart or Respiratory Failure,, Sepsis, Trauma.
Effects of Tracheal Intubation on Ventilation With a Laryngeal Mask During Percutaneous Dilatation Tracheostomy
The length of tracheal intubation may affect the subsequent ventilation with a laryngeal mask during percutaneous tracheostomy.
- Trial name
- NCT00771784
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- University of Padova
Influenza, Human, Vaccination; Sepsis
Nudging for Vaccination : Efficacity and Acceptability Among Medical Students
Nudge is a set of methods aimed at helping people adopt a behavior by a gentle prompt, conscious or not. Classically, Nudges rely on heuristics and cognitive biases.
- Trial name
- NCT03768596
- Testing
- Nudge, vaccination form
- Where
- France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Adriaan Barbaroux
Sepsis
Procalcitonin in Diagnosis of Bacterial Infections in Young Infants
A diagnostic accuracy study investigating the accuracy of procalcitonin in diagnosing invasive bacterial infections in your infants.
- Trial name
- NCT03509727
- Where
- United Kingdom
- Volunteers
- 126 people
- Sponsor
- Belfast Health and Social Care Trust
CLABSI - Central Line Associated Bloodstream Infection
Efficacy & Cost Effectiveness of Antimicrobial-impregnated CVCs in CLABSI Prevention in a Malaysia Adult ICU
Central venous catheters (CVCs) are indispensable in modern critical care. However, CVC usage is associated with complications, including central line-associated bloodstream infections (CLABSIs), which in turn, is translated to…
- Trial name
- NCT05959018
- Testing
- Arrow Three-Lumen Central Venous Catheter, Arrowg+ard Blue Plus® Three-Lumen Central Venous Catheter
- Where
- Malaysia
- Volunteers
- 110 people
- Sponsor
- University of Malaya
Sepsis
Red Cell Distribution Width Versus Presepsin (Soluble CD14) as a Prognostic Marker in Critically-ill Sepsis Patients
Presepsin (soluble CD14 subtype) is a novel marker with growing body of evidence supporting its accuracy and value for the diagnosis of sepsis. Patients with sepsis showed higher Prsepsin levels compared to those with SIRS.
- Trial name
- NCT03796715
- Testing
- Red Cell Distribution Width (RDW), Presepsin (sCD14-ST)
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Ain Shams University
Sepsis
Omega-3 Fatty Acid for Critically Ill Patients.
Sepsis is the most common reason for intensive care unit (ICU) admission. Sepsis flares up the systemic inflammatory response with its mediators.
- Trial name
- NCT03388450
- Testing
- Omega 3
- Volunteers
- 110 people
- Sponsor
- Menoufia University
Infection, Sepsis
Study of Obese Patients Comparing Two Vancomycin Loading Dose Regimens
Obesity alters the movement through the body of several antibiotics, including vancomycin. Based on literature to date, total body weight should be used to determine dosages and shorter dosing intervals may be needed.
- Conditions
- Infection, Sepsis, Obesity
- Trial name
- NCT02764359
- Testing
- IV vancomycin
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- CAMC Health System
Septic Shock, Sepsis
The Effect of Early Norepinephrine on Stroke Volume Index, Cardiac Index, Lactate, and Arterial Elastance in Pediatric Septic Shock
The complexity of pediatric septic shock arise from its varied pathophysiology, which includes systemic inflammation, cardiovascular collapse, and multiple organ dysfunction.
- Trial name
- NCT06461390
- Testing
- Norepinephrine, Ringer's Lactate
- Where
- Indonesia
- Volunteers
- 42 people
- Sponsor
- Universitas Indonesia
Severe Sepsis With Septic Shock
Evaluating a CytoSorb Score in Septic Shock
Systemic hyperinflammatory states, e.g. triggered by infection/sepsis, represent a major challenge for modern medicine. After an initially localized onset, inflammation can extend to an excessive, uncontrolled inflammatory…
- Trial name
- ECSISS (NCT03977688)
- Testing
- Cytokin Adsorption
- Where
- Germany
- Volunteers
- 500 people
- Sponsor
- Klinikum Emden
Bacteremia
Mortality of MBL-producing Enterobacteriaceae Bacteremias with the Combined Use of Ceftazidime-avibactam and Aztreonam Vs. Other Active Antibiotics. a Multicenter Target Trial Emulation.
Ceftazidime-avibactam and aztreonam combination (CAZAVI + ATM) presents a potential alternative for the treatment of metallo-beta-lactamase (MBL)-type carbapenemase-producing Enterobacteriaceae (CPE) bacteremia, particularly…
- Trial name
- NCT06419296
- Where
- 16 sites in Argentina
- Volunteers
- 265 people
- Sponsor
- Hospital Italiano de Buenos Aires
Sepsis, Critical Illness
Methionine Metabolism in Parenterally Fed Pediatric Sepsis
Critically ill children have abnormal utilization of nutrients such as glucose, lipids and protein. Protein synthesis is increased mainly in the form of immune and signaling proteins, while synthesis of muscle and structural…
- Trial name
- NCT01891682
- Testing
- Observational
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- The Cleveland Clinic
SIRS, Sepsis
SIRS and Bacterial Sepsis Discrimination by Biomarkers in ICU
Aim of the study : The primary aim of the investigators study is to highlight the presence of biomarkers (biological indicators of the presence of inflammation or infection) of infectious processes during the systemic…
- Conditions
- SIRS, Sepsis, Severe Sepsis, Septic Shock
- Trial name
- Captain (NCT01378169)
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Jaundice and Sepsis in Neonates
Ceftriaxone and Jaundice in Neonates
Ceftriaxone is an antibiotic often used for the management of sepsis. Neonates commonly have jaundice during the first postnatal week.
- Trial name
- CEFT (NCT03133637)
- Testing
- ceftriaxone
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of Rochester
Sepsis, Multiorgan Failure
MAnual Lymphatic DrAinage to iMprove the outcomE of Patients After Septic Shock
Antimicrobial and supportive therapeutic interventions in patients with septic shock are usually effective - procalcitonin and interleukin-6 levels fall rapidly in most cases, and noradrenaline support can be discontinued within…
- Conditions
- Sepsis, Multiorgan Failure, Inflammatory Response, Septic Shock
- Trial name
- MADAME (NCT05874895)
- Testing
- Manual Lymphatic Drainage, Usual Care
- Where
- Czechia
- Volunteers
- 24 people
- Sponsor
- University Hospital Ostrava
Septic Shock Point Prevalence, Sepsis
İntensive Care Sepsis Prevelance in Turkey (INSEP-TURK)
Sepsis is a life-threatening condition characterized by a dysregulated host response to infection, leading to tissue damage, multiple organ dysfunction (MODS), disseminated intravascular coagulation (DIC), and high mortality.
- Trial name
- INSEP-TURK (NCT07283588)
- Where
- Turkey (Türkiye)
- Volunteers
- 850 people
- Sponsor
- Gulhane Training and Research Hospital
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.