Clinical trials: Septoplasty
Effect of Drugs
Comparative Effect of Hypotensive Anaesthesia on Event Related Potentials, Quantitative Electroencephalograghy
AIM OF THE WORK The aim of this work was to compare the effect of hypotensive anaesthesia using Nitroglycerine versus phentolamine on Event related potentials, quantitative Electroencephalograghy and cognitive function, in…
- Trial name
- NCT04110808
- Testing
- hypotensive anaesthesia using Nitroglycerine
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Ventilation Mode, Pleth Variability Index
Effects of Volume and Pressure-Controlled Ventilation on Cerebral SpO2, PI, and PVI Index in Septoplasty
Objective: This study was designed to evaluate the accuracy of Pleth Variability Index (PVI), Perfusion Index (PI) and Regional Oxygen Saturation (rSO2) in both ventilation modes in patients undergoing septorhinoplasty operation…
- Conditions
- Ventilation Mode, Pleth Variability Index, Perfusion Index, Regional Cerebral Oxygen Saturation
- Trial name
- NCT06407362
- Testing
- Cerebral Oxygen Saturation
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sanliurfa Mehmet Akif Inan Education and Research Hospital
Nasal Septum Deviation
Effects of Hypotensive Anesthesia on Thiol Disulphide Balance
Oxidative stress at the cellular level and the effects of the antioxidant system on the anesthetic drugs make the anesthesia method more important.
- Trial name
- NCT03501563
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Nasal Septum; Deviation, Congenital, Nasal Obstruction
Suture-based, Minimally Invasive Technique Used to Correct NSD
Nasal Septal Deviation (NSD) is one of the most common indications for surgery seen by ENT physicians, however, correction requires open surgery which is associated with several weeks of recovery.
- Trial name
- NCT04891263
- Testing
- Suture-Septoplasty, Surgical suture
- Where
- 2 sites in United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Stanford University
Postoperative Pain
Intravenous Paracetamol Compared Dexketoprofen for Postoperative Analgesia After Septoplasty
The investigators conducted a prospective, randomized, double blind study to compare the effectiveness of intravenous paracetamol and dexketoprofen for preventing pain during first 24 hours postoperative period in adult patient…
- Trial name
- NCT02602197
- Testing
- Paracetamol, Dexketoprofen
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Baskent University
Agitation
Effect of Deksmedetomidine and Remifentanil in Extubation Agitation
To compare the effect of two different agents deksmedetomidine, remifentanil and placebo, agitation and recovery condition, on nasal septum operation.
- Trial name
- EA (NCT02104297)
- Testing
- deksmedetomidine, Remifentanil, Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Septoplasty
Silastic Sheet Usefulness Following Septoplasty
This study aimed to evaluate the effectiveness of silastic septal splint in reducing the rates of complications, decreasing the post-operative pain, and improving satisfaction in comparison to quilting suturing technique.
- Trial name
- NCT04921462
- Testing
- Septoplasty surgery
- Where
- Saudi Arabia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz Medical City
Outpatient Surgery, Pain, Postoperative
Patient Narcotic Requirements After Outpatient Otolaryngology Procedures
Patient's pain level and narcotic requirements will be evaluated after routine outpatient Otolaryngology procedures. This will be done by having study participants record their pain level and medication usage from home.
- Trial name
- NCT03404518
- Testing
- Norco, Ibuprofen
- Where
- 2 sites in United States
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Nasal Septum, Irregular, Nasal Septal Defect
Determination of the Frequency and Predictors of Difficult Intubation in Septoplasty Operations
Deviated septum is among the most prevalent etiologies of nasal obstruction. Congenital or acquired deformities of the nasal septum have been demonstrated to result in partial obstruction of the airflow, thereby causing…
- Conditions
- Nasal Septum, Irregular, Nasal Septal Defect, Difficult Airway, Difficult Endotracheal Intubation
- Trial name
- NCT06884592
- Testing
- Difficult Intubation
- Where
- Turkey (Türkiye)
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Nasal Obstruction, Deviated Nasal Septum
Diagnosis of Respiratory Disorders by the Numerical Modeling.
Chronic Nasal obstruction (CNO) is not currently measurable objectively because clinicians use validated declarative self-questionnaires whose results are linked to the level of understanding, the acute or chronic clinical…
- Trial name
- JUNE (NCT06670261)
- Testing
- Data collection
- Where
- France
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Nasal Septum
Study of the ENTact Septal Staple System for Tissue Approximation During Septoplasty
The purpose of this research study is to learn more about the ENTact™ Septal Staple System device performance and to collect information to support its premarket application.
- Trial name
- NCT00740480
- Where
- 3 sites in United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- ENTrigue Surgical, Inc.
Nasal Septum; Deviation, Nasal Septal Srur
Outcomes of PRF on Septoplasty in Patient With Nasal Septal Deviation
The aim of this study is to assess the effectiveness of Platelet-Rich Fibrin (PRF) in improving postoperative healing, reducing complications, and enhancing functional outcomes in patients undergoing septoplasty
- Trial name
- NCT06996106
- Testing
- Effect of Platelet Rich Fibrin on Septoplasty
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Deviated Septum, Opioid Free Anesthesia
Opioid Free Versus Opioid Based General Anesthesia in Septoplasty Under Nociception Level Guidance
Prospactive observational Clinical study
- Trial name
- NCT07786727
- Testing
- OFA
- Where
- Greece
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Democritus University of Thrace
Septal Deformity, Nasal Obstruction
Clinical Extend Study to Evaluate Safety and Effectiveness of TnR Nasal Mesh for Correction of Nasal Septum on Patients
The purpose of this observation study is to evaluate long term safety and efficacy at 2~3 years after surgery on patients who have completed nasal septal deformity surgery using TnR Nasal Mesh.
- Trial name
- NCT04332575
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- T&R Biofab Co., Ltd.
Nasal Obstruction, Septoplasty Surgeries
Effects of Surgical Correction of Nasal Obstruction on Oxygen Uptake and Ventilation Volume
This retrospective study aims to evaluate the effect of surgical correction of nasal obstruction on aerobic performance parameters in male athletes aged 20-32 years.
- Conditions
- Nasal Obstruction, Septoplasty Surgeries, Athletic Performance
- Trial name
- NCT06957262
- Testing
- Surgical correction of nasal obstruction
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Tuba Melekoğlu
Nasal Fracture, Deviated Nasal Septum
Preoperative Nerve Block for Rhinoplasty/Septoplasty
Addiction is an inherent risk when prescribing opiates for pain relief, and methods to reduce its use or amount prescribed can help mitigate this risk for addiction.
- Trial name
- NCT03780478
- Testing
- Nerve block
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Septum Deviated, Septoplasty/Septorhinoplasty
Could Medical Educational Video Reduce Anxiety Before Nasal Packing Removal After Septoplasty/Septorhinoplasty?
Septoplasty/septorhinoplasty is one of the most common surgical procedures performed in ENT clinics. Intranasal packing is widely used post-operatively for nasal septum stabilization and bleeding control.
- Trial name
- NCT03861104
- Testing
- medical educational video
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Baskent University
Postoperative Pain
Effectiveness of Bilateral Endoscopic Sphenopalatine Ganglion Block on Postoperative Pain After Septoplasty
The aim of this clinical study will investigate the efficacy of sphenopalatine ganglion block in the treatment of postoperative pain.it will also be learnt whether it reduces the consumption of analgesics in postoperative…
- Trial name
- NCT06695624
- Testing
- Sphenopalatine Ganglion Block
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Umraniye Education and Research Hospital
Septoplasty Surgeries
Cold Dissection vs Electrocautry on TCR in Septoplasty
This study aims to address these gaps by comparing the incidence of TCR during septoplasty performed using cold dissection versus electrocautery, while also incorporating a novel assessment of surgical force.
- Trial name
- TCR (NCT07425834)
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Fatmaelzahraa Omar Mahmoud Bahr
Septal Deformity, Nasal Obstruction
A Clinical Study to Evaluate the Safety and Efficacy of Surgical Material for Nasal Septoplasty
The purpose of this clinical trial is to evaluate safety and efficacy of TnR mesh for patients who need nasal septoplasty for septal deformity with nasal obstruction.
- Trial name
- NCT03088618
- Testing
- Nasal septoplasty
- Where
- 2 sites in South Korea
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- T&R Biofab Co., Ltd.