Clinical trials: Septoplasty Surgeries
Empty Nose Syndrome
Trigeminal Endonasal Perception: A Predictor for Septoplasty Outcome
This study investigates wether patients with increased trigeminal perception threshold and low expression of TRP channels have more often nasal blockage despite functionally successful nasal surgery (TRP channel = transient…
- Trial name
- NCT02230423
- Testing
- Nasal surgery
- Where
- Switzerland
- Volunteers
- 140 people
- Sponsor
- University of Zurich
Septoplasty Surgeries
Cold Dissection vs Electrocautry on TCR in Septoplasty
This study aims to address these gaps by comparing the incidence of TCR during septoplasty performed using cold dissection versus electrocautery, while also incorporating a novel assessment of surgical force.
- Trial name
- TCR (NCT07425834)
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Fatmaelzahraa Omar Mahmoud Bahr
Nasal Septum, Irregular, Nasal Septal Defect
Determination of the Frequency and Predictors of Difficult Intubation in Septoplasty Operations
Deviated septum is among the most prevalent etiologies of nasal obstruction. Congenital or acquired deformities of the nasal septum have been demonstrated to result in partial obstruction of the airflow, thereby causing…
- Conditions
- Nasal Septum, Irregular, Nasal Septal Defect, Difficult Airway, Difficult Endotracheal Intubation
- Trial name
- NCT06884592
- Testing
- Difficult Intubation
- Where
- Turkey (Türkiye)
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Nasal Obstruction
Comparison of a Septal Stapler to Suture Closure in Nasal Septoplasty
The primary objective of this study is to determine if there is a time savings in the operating room by using a septal stapler instead of suture in closure of primary septoplasty.
- Trial name
- NCT01541839
- Testing
- Septal Stapler
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- University of Alberta
Sore Throat
Soaked Pharyngeal Packing Agents in Septoplasty
Postoperative sore throat (POST) is a frequent and distressing complication after general anesthesia with endotracheal intubation, particularly in nasal surgery for example, functional endoscopic sinus surgery, septoplasty, or…
- Trial name
- Throat pack (NCT07486544)
- Testing
- dexamethasone 8mg
- Where
- Egypt
- Volunteers
- 65 people
- Sponsor
- Assiut University
Headache
Rhinogenic Headache Improvement After Nasal Operation
Objective: To determine the efficacy of surgical correction of intranasal mucosal contact points in improving quality of life and decreasing medication use in patients with rhinogenic headaches.
- Trial name
- RHINO (NCT00580307)
- Testing
- Septoplasty, Septoplasty and endoscopic contact point correction
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Missouri-Columbia
Rhinosinusitis, Sinusitis
Clinical Outcomes and Patient Satisfaction With Velnez Versus Nasopore in Nasal Surgery
This clinical trial evaluated two absorbable nasal packing materials - VELNEZ and NASOPORE - in adult patients (18-70 years) who underwent nasal surgery, including septoplasty, FESS, or turbinoplasty.
- Conditions
- Rhinosinusitis, Sinusitis, Chronic Rhino-sinusitis
- Trial name
- NCT07560254
- Testing
- VELNEZ Nasal Pack, NASOPORE Nasal Pack
- Where
- Malaysia
- Volunteers
- 20 people
- Sponsor
- Ayu, Inc.
Cough
The Effect-site Concentration of Remifentanil for Preventing Cough During Emergence From Balanced Anesthesia for Nasal Surgery
After nasal surgery, emergence cough or straining will produce venous engorgement and increase bleeding from the surgical site, so the necessity for smooth extubation without severe cough during emergence provides a challenge for…
- Trial name
- NCT01291849
- Testing
- Dixon up-and-down method
- Where
- South Korea
- Volunteers
- 24 people
- Sponsor
- Yonsei University
Nasal Septum Deviation
Disarticulation Septoplasty Versus Classical Way
The objective of this study is to determine which of the two techniques (disarticulation septoplasty versus open surgery) offers the best functional results for correcting symptomatic deviations of the nasal septum.
- Trial name
- DSARTICULATION (NCT07412340)
- Testing
- Comparison of functional improvement in nasal breathing between the two techniques using questionnaires administered to patients by their practitioners in routine practice
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Hôpital NOVO
Ventilation Mode, Pleth Variability Index
Effects of Volume and Pressure-Controlled Ventilation on Cerebral SpO2, PI, and PVI Index in Septoplasty
Objective: This study was designed to evaluate the accuracy of Pleth Variability Index (PVI), Perfusion Index (PI) and Regional Oxygen Saturation (rSO2) in both ventilation modes in patients undergoing septorhinoplasty operation…
- Conditions
- Ventilation Mode, Pleth Variability Index, Perfusion Index, Regional Cerebral Oxygen Saturation
- Trial name
- NCT06407362
- Testing
- Cerebral Oxygen Saturation
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sanliurfa Mehmet Akif Inan Education and Research Hospital
Nausea and Vomiting, Postoperative, Septoplasty/Septorhinoplasty
Effect of Fresh Gas Flow Differences on Postoperative Nausea and Vomiting
The aim of this study is to investigate the effect of fresh gas flow applied during general anesthesia on the incidence of postoperative nausea and vomiting in patients undergoing septorhinoplasty surgery.
- Trial name
- NCT06952946
- Testing
- 0.5 lt/dk fresh gas flow, 2 lt/dk fresh gas flow, 4 lt/dk fresh gas flow
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Adiyaman University Research Hospital
Airway Complication of Anesthesia, Septoplasty
Video Laryngeal Mask vs. Endotracheal Tube in Septoplasty
This single-center, prospective, observational, comparative study evaluated airway management using the SaCoVLM™ video laryngeal mask airway (VLMA) and a conventional endotracheal tube (ETT) in adult patients undergoing elective…
- Trial name
- NCT06950957
- Testing
- Video Laryngeal Mask Airway (VLMA), Endotracheal Tube (ETT)
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Samsun University
Hypotension During Surgery, NGAL
Controlled Hypotension and Renal Injury During Septoplasty
This prospective randomized single-blind study investigated the effects of two different mean arterial pressure (MAP) targets during controlled hypotension on renal injury in patients undergoing septoplasty.
- Conditions
- Hypotension During Surgery, NGAL, Kidney Injury
- Trial name
- NCT07662577
- Testing
- Controlled Hypotension (MAP 50-57 mmHg), Controlled Hypotension (MAP 58-65 mmHg)
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Sinusitis
Endoscopic Sinus Surgery for Refractory Chronic Sinusitis
Chronic sinusitis is a disease involving severe swelling of your facial sinuses and nasal cavity. Chronic sinusitis is a common disorder and roughly 5% of adult men and women have chronic sinusitis in Canada.
- Trial name
- NCT02506426
- Testing
- Endoscopic sinus surgery + Septoplasty, Septoplasty alone
- Where
- 2 sites in Canada
- Volunteers
- 44 people
- Sponsor
- University of Calgary
Pain Control After Functional Endoscopic Sinus Surgery and Septoplasty
Are NSAIDs Effective Enough for Postoperative Pain Control After Functional Endoscopic Sinus Surgery and Septoplasty
The purpose of this study is to compare the level of pain control in patients receiving non-steroidal anti-inflammatory drugs (NSAIDs) to those receiving opioids in the postoperative period after endoscopic sinus surgery (ESS)…
- Trial name
- NCT03605914
- Testing
- diclofenac, Norco
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- The University of Texas Health Science Center, Houston
Deviated Nasal Septum
Perioperative Administration of Pregabalin for Pain After Septoplasty
Pregabalin is used for the treatment of neuropathic pain and has shown analgesic efficacy in postoperative pain. The aim of this randomized, double-blinded, placebo-controlled trial was to investigate the efficacy and safety of…
- Trial name
- NCT01370915
- Testing
- Pregabalin (Lyrica)
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Samsung Medical Center
Septal Deformity, Nasal Obstruction
A Clinical Study to Evaluate the Safety and Efficacy of Surgical Material for Nasal Septoplasty
The purpose of this clinical trial is to evaluate safety and efficacy of TnR mesh for patients who need nasal septoplasty for septal deformity with nasal obstruction.
- Trial name
- NCT03088618
- Testing
- Nasal septoplasty
- Where
- 2 sites in South Korea
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- T&R Biofab Co., Ltd.
Intranasal Surgery
Traditional Septoplasty Vs Endoscopic Septoplasty for Treating Deviated Nasal Septum
In this study the investigators aim to assess whether endoscopic septoplasty is effective at improving patients QOL and reducing postoperative signs and complications.
- Trial name
- NCT02653950
- Testing
- Endoscopic septoplasty, Traditional septoplasty
- Volunteers
- 60 people
- Sponsor
- Rambam Health Care Campus
Therapeutic (Nonsurgical) and Rehabilitative Anesthesiology Devices Associated With Adverse Incidents
Electroacupuncture Anesthesia for Nasal Sinus Surgery and Mammaplasty
The purpose of this study is to verify the intraoperative analgesia of electroacupuncture in patients undergoing selective nasal sinus surgery and mammaplasty.
- Trial name
- NCT01700855
- Testing
- non-electroacupuncture, Electroacupuncture
- Where
- China
- Volunteers
- 137 people
- Sponsor
- Xijing Hospital
Hypotension During Surgery
Controlled Hypotension in Rhinoplasty and Septoplasty: Incidence of Cognitive Dysfunction and Delirium
Controlled hypotension application is a commonly preferred anesthesia practice during surgical procedures, particularly in regions with rich tissue perfusion, aiming to reduce bleeding, enhance surgical field visibility, and…
- Trial name
- NCT06238973
- Testing
- Group Low, Group Middle
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Hitit University