Clinical trials: Sequelae
Stroke Sequelae, Stroke ( 3 Months After Onset)
Clinical Implementation of Multichannel Functional Electrical Stimulation Device for Gait Rehabilitation in Subchronic Stroke: A Feasibility Study
The goal of this interventional study is to evaluate the effect of multichannel functionnal electrical stimulation for subchronic stroke gait rehabilitation.
- Trial name
- NCT07211672
- Testing
- Multichannel functionnal electrical stimulation
- Volunteers
- 5 people
- Sponsor
- TOPMED
Stroke; Sequelae
Postural Decoding for Post-Stroke Shoulder Pain: A RCT.
Brief Summary Purpose of the Study: This clinical trial aims to determine whether Postural Decryption Technique can effectively treat hemiplegic shoulder pain (HSP) in patients recovering from stroke.
- Trial name
- NCT06763796
- Testing
- Postural Decryption Technique, Traditional Chinese Medicine (TCM) Massage Therapy
- Where
- China
- Volunteers
- 48 people
- Sponsor
- Shenzhen Baoan District Fuyong People's Hospital
Post-acute Sequelae of SARS-CoV-2 Infection, Long COVID
Paxlovid for Treatment of Long Covid
The purpose of this study is to compare whether being treated with nirmatrelvir plus ritonavir for 15 days works better than being treated with placebo plus ritonavir to reduce severe symptoms of Long Covid.
- Trial name
- STOP-PASC (NCT05576662)
- Testing
- Nirmatrelvir, Ritonavir
- Where
- United States
- Volunteers
- 168 people
- Sponsor
- Stanford University
Dental Trauma, Enamel Hypoplasia
Evaluation of Sequelae in Permanent Successors Following Traumatic Injuries to Primary Teeth
Retrospective data analysis of children with primary dental trauma and follow-up visual examination to find out the sequelae.
- Conditions
- Dental Trauma, Enamel Hypoplasia, Sequelae, Sequelae Successors
- Trial name
- NCT07134348
- Where
- Turkey (Türkiye)
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- Zeynep Aslı GÜÇLÜ
Muscle Spasticity, Stroke Sequelae
Comparison of Two Botox Injection Techniques to Improve Gait
According to our hypothesis, the use of HD-EMG shall allow an accurate localization of the innervations zones of the muscles, offering a better complement to the methodology applied so far to define the botulinum neurotoxin…
- Conditions
- Muscle Spasticity, Stroke Sequelae, Spasticity as Sequela of Stroke, Gait Disorders, Neurologic
- Trial name
- NCT07124806
- Testing
- Botulinum toxin guided by ultrasonography and anatomical references, Botulinum neurotoxin guided by ultrasonography and in vivo location of innervation zones guided by high-density electromyography
- Where
- 2 sites in Chile
- Volunteers
- 18 people
- Sponsor
- Universidad de los Andes, Chile
Amputation; Postoperative, Sequelae
Hyperbaric Oxygen and Outcome After Below Knee Amputations
This study is being conducted to assess the utility of hyperbaric oxygen as an adjunctive treatment to reduce postoperative complications.
- Trial name
- NCT04717557
- Testing
- Hyperbaric Oxygen
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Duke University
SARS-CoV-2 Acute Respiratory Disease, Myalgic Encephalomyelitis
Does a Technology Enabled Multi-disciplinary Team-based Care Model for the Management of Long COVID and Other Fatiguing Illnesses Improve Clinical Care of Patients and Represent a Sustainable Approach Within a Federally Qualified Health Center?
The primary objective of the present research is to determine the effectiveness of Family Health Center of San Diego's Long COVID and Fatiguing Illness Recovery Program (LC\&FIRP) on clinician- and patient-level outcomes.
- Conditions
- SARS-CoV-2 Acute Respiratory Disease, Myalgic Encephalomyelitis, Chronic Fatigue Syndrome, Post-acute Sequelae of SARS-COV-2 Infection
- Trial name
- LC&FIRP (NCT05167227)
- Testing
- Extension for Community Healthcare Outcomes
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Family Health Centers of San Diego
Covid19, Sequelae of; Infection
Clinical Trial of Niagen to Examine Recovery in People With Persistent Cognitive and Physical Symptoms After COVID-19
The study will assess whether Niagen, a safe dietary supplement, improves recovery of COVID-19 related symptoms in individuals who were infected at least 2 months prior to study entry ("Long-COVID" "Long-haulers").
- Conditions
- Covid19, Sequelae of; Infection, Cognitive Symptom
- Trial name
- NCT04809974
- Testing
- Niagen
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Massachusetts General Hospital
Stroke Sequelae, Gait Disorders, Neurologic
Efficacy of Trans-spinal Magnetic Stimulation on Functional Mobility in Chronic Stroke Patients
The goal of this clinical trial is to learn if trans-spinal magnetic stimulation works to treat gait disorders in chronic stroke adults. It will also learn about the safety of trans-spinal magnetic stimulation.
- Conditions
- Stroke Sequelae, Gait Disorders, Neurologic, Stroke
- Trial name
- NCT06593184
- Testing
- Trans-spinal magnetic stimulation
- Where
- 3 sites in Brazil
- Volunteers
- 30 people
- Sponsor
- Universidade Federal de Pernambuco
Stroke Sequelae
Effect of Air Splints on Sensoriomotor Disturbances of the Affected Upper Extremity and Trunk Control in the Adult Post-stroke Patient
Objective: Sensory impairment in the affected upper limb occurs in approximately 50% of post-stroke patients and negatively impacts functional capacity and quality of life.
- Trial name
- NCT07029061
- Testing
- Air splints
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Alfonso X El Sabio University
Covid19 Sequelae
Yale COVID-19 Recovery Study
The general purpose of the study is to determine the change in immune responses in people with Post-Acute Sequelae of SARS-CoV-2 Infection (PASC) after vaccination.
- Trial name
- NCT04895189
- Testing
- No intervention
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Yale University
SARS-CoV-2 Infection, Post-acute Sequelae of SARS-CoV-2
The Canadian Respiratory Research Network Long COVID-19 Study
Preliminary studies suggest that COVID-19 causes long-term lung damage, even in young, otherwise healthy people who did not need to go to hospital or the ICU.
- Trial name
- NCT05181670
- Where
- 8 sites in Canada
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Stroke, Stroke Sequelae
Noninvasive VNS to Facilitate Excitability in Motor Cortex
Transcranial Magnetic Stimulation (TMS) positively influences motor rehabilitation in stroke recovery. Transcutaneous auricular vagus nerve stimulation (taVNS) has shown effects on cortical plasticity.
- Conditions
- Stroke, Stroke Sequelae, Motor Activity
- Trial name
- NCT04130646
- Testing
- Transcranial Magnetic Stimulation, transcutaneous auricular vagus nerve stimulation (taVNS)
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Stroke, Complication, Stroke
Neuromotor Prosthetic to Treat Stroke-Related Paresis
The purpose of the research is to develop a new medical device prototype to restore functional movement of an arm made weak due to a chronic stroke
- Conditions
- Stroke, Complication, Stroke, Stroke Sequelae, Hemiparesis
- Trial name
- Cortimo (NCT03913286)
- Testing
- Cortimo
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Thomas Jefferson University
COVID-19, Post Acute Sequelae of SARS-CoV-2
Mindfulness Intervention for Post-Covid Symptoms
The purpose of this study is to assess the feasibility of using a wearable brain-sensing wellness device (Muse-S) to potentially reduce stress and anxiety during Post-Covid, which is characterized by increased stress and anxiety.
- Trial name
- NCT05199233
- Testing
- Muse S™ Headband system
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Mayo Clinic
Meniscectomy Sequelae
Functionality of Lower Limbs in Patients Who Have Undergone Knee Meniscectomy
Introduction. Meniscal lesions are common and are associated with the development of osteoarthritis of the knee. Work activities that cause mechanical stress can lead to acute or chronic injuries.
- Trial name
- NCT06920394
- Testing
- Survey using a questionnaire.
- Where
- Spain
- Volunteers
- 89 people
- Sponsor
- Universidad Católica San Antonio de Murcia
PASC Post Acute Sequelae of COVID 19, Long COVID
From Inflammation to Remodelling Towards Personalized Diagnosis in Post-acute Sequelae of COVID-19
Rationale: The diagnosis and pathogenesis of long COVID remains unknown. We have previously shown that [68Ga]FAPI Positron Emission Tomography-Computed Tomography (PET/CT) imaging shows potential for diagnosis and molecular…
- Conditions
- PASC Post Acute Sequelae of COVID 19, Long COVID, Long Covid-19, PASC
- Trial name
- LIBERATE (NCT06911476)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Motor Impairment, Motor Impairments
Transcutaneous Auricular Vagus Nerve Stimulation in Patients With Stroke
This study will evaluate the effects of transcutaneous vagus nerve stimulation in combination with physical rehabilitation on upper limb motor function of patients with stroke.
- Conditions
- Motor Impairment, Motor Impairments, Stroke, Stroke; Sequelae
- Trial name
- INPULSE (NCT06895005)
- Testing
- Transcutaneous auricular vagus nerve stimulation + rehabilitation therapy
- Where
- Colombia
- Volunteers
- 30 people
- Sponsor
- Fundación Cardiovascular de Colombia
COVID-19, Long Covid
"Long COVID-19" on the Human Brain
Over one million Canadians have been infected by COVID-19. Many people who have been infected by COVID-19 experience negative mental symptoms, such as "brain fog" and fatigue.
- Conditions
- COVID-19, Long Covid, Post Acute Sequelae of COVID-19
- Trial name
- NCT05433324
- Testing
- MRI and PET Scans
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Carbon Monoxide Poisoning, Delayed Neurocognitive Sequelae
The Efficacy of Dexamethasone in Combination With N-acetylcysteine in Preventing Neurocognitive Sequelae Due to Carbon Monoxide Poisoning
Background and Aim: Carbon monoxide (CO) poisoning is a significant public health issue that can cause delayed neuropsychological sequelae (DNS). DNS mechanisms involve oxidative stress, inflammation, and immune injury.
- Trial name
- NCT06811675
- Testing
- Dexamethasone and N-acetylcysteine (NAC)
- Where
- Taiwan
- Volunteers
- 128 people
- Sponsor
- China Medical University Hospital