Clinical trials: Sequelae of Stroke
Brain Injury, Vascular, Sequelae
The Effectiveness of Core Stability Exercises
This study assess the effectiveness of core stability exercises performed in subacute phase of stroke. Half of participants will receive conventional physiotherapy, while the other half will receive core stability exercises and…
- Conditions
- Brain Injury, Vascular, Sequelae, Stroke Syndrome, Movement; Disorder, Treatment-Induced
- Trial name
- CORE (NCT03975985)
- Testing
- Core stability exercises (CSE), Conventional Physiotherapy
- Where
- Spain
- Volunteers
- 87 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Stroke, Stroke Sequelae
Novel Wrist Sensor System to Promote Hemiparetic Arm Use in Home Daily Life of Chronic Stroke Survivors
The proposed study is a two-arm randomized clinical trial designed to assess the effects of the StrokeWear system on clinical outcomes over a period of 6-months in chronic stroke survivors.
- Conditions
- Stroke, Stroke Sequelae, Hemiparesis;Poststroke/CVA
- Trial name
- NCT05626894
- Testing
- StrokeWear Motor and Behavioral Intervention, Usual Care
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Spaulding Rehabilitation Hospital
Cerebrovascular Disorders, Memory
Roflumilast to Treat Cognitive Sequela After Stroke
The aim of the current project is to validate the effects of chronic rolflumilast treatment (12 weeks) on cognitive functions (i.e.
- Conditions
- Cerebrovascular Disorders, Memory, Functional Recovery, Drug Intervention
- Trial name
- ROSTMEMA (NCT04854811)
- Testing
- Roflumilast Oral Tablet
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- Maastricht University
Stroke Sequelae, Spasticity, Muscle
Effects of CRet Associated With Functional Massage (F.M) on Gait and Functionality in Post-stroke Spasticity
The purpose of this study is to assess the immediate effects of CRet associated to Functional Massage (F.M) in terms of gait and functionality after stroke
- Conditions
- Stroke Sequelae, Spasticity, Muscle, Massage, Electrotherapy
- Trial name
- NCT04851756
- Testing
- CRet
- Where
- Spain
- Volunteers
- 36 people
- Sponsor
- Universitat Internacional de Catalunya
Stroke, Hemiparesis;Poststroke/CVA
Muscle Oxygenation and Spasticity in Hemiparetic Stroke Patients
Conditions such as hemiparesis, sensory and motor impairment, perceptual impairment, cognitive impairment, aphasia, and dysphagia may be observed after stroke.
- Conditions
- Stroke, Hemiparesis;Poststroke/CVA, Spasticity as Sequela of Stroke
- Trial name
- NCT06362954
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ankara Medipol University
Spasticity as Sequela of Stroke, Nerve Transfers
Nerve Transfers in Post-stroke Spasticity
Stroke is nowadays a leading cause of disability with devastating sequelae. Upper limb spasticity is one of them. Nevertheless, not all the muscles are equally affected, as some may turn spastic or paretic and other remain…
- Trial name
- NCT04437056
- Testing
- Cognitive nerve transfers to spastic upper extremity muscles in stroke patients
- Where
- Austria
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Stroke, Spasticity as Sequela of Stroke
Effect of ESWT Applied After Botulinum Toxin Injection on Ankle Spasticity in Stroke Patients.
Stroke is the second most common cause of death and the third most important cause of disability worldwide, with an annual death rate of 5.5 million.
- Trial name
- NCT06126523
- Testing
- Radial Extracorporeal Shock Wave Therapy ONCE, Radial Extracorporeal Shock Wave Therapy TWİCE
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Saglik Bilimleri Universitesi
Dysarthria As Late Effect of Stroke
Group Intervention Study for Individuals with Dysarthria Following Stroke and Their Carers in Pakistan
Dysarthria is a common problem in Pakistan. therefore the current study aims to translate the dysarthria communication tools into urdu language for better understanding the population and the problem
- Trial name
- NCT04427670
- Testing
- Group intervention, Regular speech therapy
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Isra University
Stroke Sequelae
Therapeutic Effects of Robotic Exoskeleton-Assisted Gait Re-habilitation and Predictive Factors of Significant Improvements in Stroke Patients
Investigators aimed to examine the effectiveness of robotic exoskeleton-assisted gait training in stroke rehabilitation, and to determine predicting factors of significant improvements in post-stroke patients.
- Trial name
- NCT05825144
- Testing
- Robotic exoskeleton-assisted gait rehabilitation, Conventional rehabilitation
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- Taichung Veterans General Hospital
Stroke Sequelae, Gait Disorders, Neurologic
Efficacy of Trans-spinal Magnetic Stimulation on Functional Mobility in Chronic Stroke Patients
The goal of this clinical trial is to learn if trans-spinal magnetic stimulation works to treat gait disorders in chronic stroke adults. It will also learn about the safety of trans-spinal magnetic stimulation.
- Conditions
- Stroke Sequelae, Gait Disorders, Neurologic, Stroke
- Trial name
- NCT06593184
- Testing
- Trans-spinal magnetic stimulation
- Where
- 3 sites in Brazil
- Volunteers
- 30 people
- Sponsor
- Universidade Federal de Pernambuco
Chronic Stroke, Spasticity as Sequela of Stroke
Effects of EMG-driven Robot-assisted Therapy for the Distal Upper Limb Motor Function in the Chronic Stroke Patients With Botox Injections
Over fifty percent of stroke patients experience chronic arm hand performance problems, compromising independence in daily life activities and quality of life.
- Conditions
- Chronic Stroke, Spasticity as Sequela of Stroke, Robotic Rehabilitation
- Trial name
- NCT04502264
- Testing
- Hand of Hope, Botulinum toxin type A injection
- Where
- Taiwan
- Volunteers
- 24 people
- Sponsor
- Cheng-Hsin General Hospital
Late Effects of Cerebrovascular Accident
Main Idea Perception of Written Stories and in Pictures Among Impaired Right Hemisphere Patients
Main idea perception of written stories and in pictures among impaired right hemisphere patients Abstract The right hemisphere is considered to complement the language processing abilities of the opposite hemisphere; it is…
- Trial name
- stroke (NCT02897791)
- Testing
- written evaluations
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Stroke, Stroke Sequelae
Therapeutic Effect of Transcranial Magnetic Stimulation on Memory Impairment in Patients After Stroke
The goal of this clinical trial is to test the therapeutic effect of theta burst stimulation (TBS), which is one of stimulus pattern of repetitive transcranial magnetic stimulation, in patients with post stroke cognition…
- Conditions
- Stroke, Stroke Sequelae, Cognitive Impairment
- Trial name
- NCT05578183
- Testing
- theta burst stimulation
- Where
- China
- Sponsor
- China Rehabilitation Research Center
Stroke
Effects of Upper Limb Motor and Robotic Training Over Neuroplasticity and Function Capacity
The purpose of this study is to evaluate and compare the effects of upper limb training with Induced Constraint Therapy (ICT) or robotic therapy. No placebo therapy is used.
- Trial name
- NARLE1 (NCT02700061)
- Testing
- Robotic occupational therapy, Induced Constraint Therapy - ICT
- Where
- Brazil
- Volunteers
- 51 people
- Sponsor
- University of Sao Paulo General Hospital
Stroke Sequelae
Italian Translation and Transcultural Validation of Frenchay Activity Index and Walking Handicap Classification in Stroke
This study is aimed at providing an Italian version of two assessment tools for participation in stroke patients, the Frenchay Activity Index (FAI) and the Walking Handicap Classification (WHC) by a standardized translation and…
- Trial name
- FAIWHC (NCT04285957)
- Testing
- Questionnaire administration pre test, Questionnaire administration - validation
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Brain Injuries, Disorder of Consciousness
Long Term Effects of Soft Splints on Stroke Patients and Patients With Disorders of Consciousness
The purpose of this study is to assess the effects on upper limb spasticity of soft splints worn during three weeks three hours a day by patients with stroke or disorders of consciousness.
- Conditions
- Brain Injuries, Disorder of Consciousness, Stroke, Spasticity as Sequela of Stroke
- Trial name
- NCT03008486
- Testing
- Real soft splint (6 cm)
- Where
- Belgium
- Volunteers
- 12 people
- Sponsor
- Géraldine Martens
Stroke Sequelae, Stroke
Multiple Dose Study to Evaluate Drug-drug Interactions, Safety and Tolerability of NDC-002 in Healthy Volunteers
An Open-label, One-sequence, Three-period, Multiple-dose Study to Evaluate Drug-drug Interactions, Safety and Tolerability between NDC-002A/NDC-002B and NDC-002C in Healthy Volunteers
- Trial name
- NCT06090474
- Testing
- NDC-002
- Where
- South Korea
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Dr. Noah Biotech Inc.
Spasticity as Sequela of Stroke
A Study to Estimate How Often Post-stroke Spasticity Occurs and to Provide a Standard Guideline on the Best Way to Monitor Its Development
This study will monitor patients during the first year following their stroke. Stroke is a very serious condition where there is a sudden interruption of blood flow in the brain.
- Trial name
- EPITOME (NCT06055725)
- Where
- 55 sites in United States, France and 5 more
- Volunteers
- 1,057 people
- Sponsor
- Ipsen
Chronic Stroke
Psychometric Study of the Spanish Version of Two Upper Limb Assessment Scales in Chronic Stroke
The purpose of this cross-sectional study is to translate and cross-culturally adapt to Spanish the Motor Evaluation Scale for Upper Extremity in Stroke Patients (MESUPES) and the Stroke Upper Limb Capacity Scale (SULCS) and to…
- Trial name
- NCT05872191
- Testing
- No intervention
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- University of Valencia
Spasticity as Sequela of Stroke
Cryoneurolysis for Spasticity Treatment: Long-term Clinical Outcomes and Mechanisms in the Central Nervous System
Spasticity can make regular daily activities difficult or impossible. Cryoneurolysis is a new technique to treat spasticity that is currently being tested.
- Trial name
- NCT06958289
- Testing
- Cryoneurolysis
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- Sue Peters