Clinical trials: Sequelae of Stroke
Ischemic Stroke
Effects of Mepivacaine on the Neurological Sequelae of Cerebral Infarction
A patient, suffering from cortical blindness after a bi-occipital infarction 1 year earlier, regained near-normal vision in the right visual hemifield a few minutes after subcutaneous administration of mepivacaine.
- Trial name
- MEPI-AVC (NCT05222828)
- Testing
- Carbocaine Injectable Product
- Where
- France
- Volunteers
- 38 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Stroke Sequelae
A Multidisciplinary Telerehabilitation for Stroke Patients
Objective: Evaluate the feasibility of a multidisciplinary telerehabilitation for chronic stroke patients. Design: Chronic stroke patients eligible for multidisciplinary rehabilitation funded by the Social Insurance Institution…
- Trial name
- NCT04116190
- Testing
- Telerehabilitation, Conventional inpatient rehabilitation
- Where
- Finland
- Volunteers
- 45 people
- Sponsor
- Vetrea Terveys Oy
Stroke Sequelae, Motor Disorders
Clinical Validation of a Hybrid BCI-controlled FES for Upper Limb Rehabilitation After Stroke
The RECOMMENCER project aims at developing and testing a novel hybrid Brain Computer Interface device based on cortico-muscular connectivity, that will be employed to activate Functional Electrical Stimulation (FES) of upper limb…
- Trial name
- RECOMMENCER (NCT05511207)
- Testing
- RECOM - hBCI training, CTRL - upper limb training with FES
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- Donatella Mattia
Stroke Sequelae, Stroke
Mental Practice in Post-stroke Subjects
Among the limitations caused by cerebrovascular accident (CVA), the upper limb (MS) undergoes changes that limit the individual in his ability to maintain an active social life.
- Trial name
- NCT03251209
- Testing
- Physical practice, Mental practice, Videotherapy
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Universidade Federal do Rio Grande do Norte
Spasticity as Sequela of Stroke
Phenol and Botulinum Toxin vs Botulinum Toxin Alone for Post-Stroke Upper-Limb Spasticity
This study aims to evaluate the efficacy of a combined treatment approach for post-stroke upper limb spasticity using phenol neurolysis and botulinum toxin (BoNT).
- Trial name
- NCT07440173
- Testing
- phenol neurolysis, Botulinum Toxin - A injections
- Volunteers
- 60 people
- Sponsor
- Assiut University
Stroke Sequelae, Dependency
Evaluation of Degree of Dependency After Stroke.
Understanding the risk of dependence and its severity before hospital discharge for stroke is important for health and social care planning as instrument to prioritize people where the assistance is more appropriate in a context…
- Trial name
- NCT03451357
- Testing
- Dependence degree already certificated by Dependence Law.
- Where
- Spain
- Volunteers
- 230 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Spasticity, Muscle, Stroke Sequelae
Valuation of the Evolution of Passive Mobility in the Spastic Upper Limb After Injection of Abobotulinumtoxin(Dysport®)
Assessing the objective measurement of passive joint mobility (ROM) in the spastic upper limb with Jost's pattern III in patients with post-stroke spasticity after infiltration with BoNT-A allows to objectify the increase in…
- Conditions
- Spasticity, Muscle, Stroke Sequelae, Movement Disorders
- Trial name
- ROM-ICTUS (NCT05151874)
- Testing
- Abobotulinum toxin A
- Where
- Spain
- Volunteers
- 12 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Hemiparesis, Stroke Sequelae
Neural Mechanisms of Motor Recovery With Technology Assisted Training
Stroke is a leading cause of disability that often impairs arm function and activities of daily living. The costs of rehabilitation are significant and practical constraints often limit therapy to the first few months after…
- Trial name
- NCT05560867
- Testing
- robot-assisted training
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Maryland, Baltimore
Stroke
Study on the Clinical Efficacy of Chinese Medicine Treatment of Sequelae of Apoplexy
This project is one multi-center, a prospective cohort study, based on 1660 cases of ischemic stroke patients with the treatment of 3 months, and 21 months of follow-up observation in order to clarify the advantages and…
- Trial name
- NCT03077984
- Testing
- Chinese medicine treatment
- Volunteers
- 1,660 people
- Sponsor
- Tongsheng Su
Stroke, Ischemic, Stroke Hemorrhagic
Radial Extracorporeal Shock Wave Therapy and Visual Feedback Balance Training on Lower Limb Post-Stroke Spasticity, Trunk Performance and Balance:
This study assess the relationship between lower limb spasticity and trunk movements during static and dynamic balance in post-stroke patients who also underwent conventional physical therapy, visual feedback balance training and…
- Conditions
- Stroke, Ischemic, Stroke Hemorrhagic, Spasticity as Sequela of Stroke, Spastic Gait
- Trial name
- NCT05196633
- Testing
- radial extracorporeal shock wave therapy
- Where
- Romania
- Volunteers
- 23 people
- Sponsor
- Carol Davila University of Medicine and Pharmacy
Stroke Sequelae
Therapeutic Effects of Robotic Exoskeleton-Assisted Gait Re-habilitation and Predictive Factors of Significant Improvements in Stroke Patients
Investigators aimed to examine the effectiveness of robotic exoskeleton-assisted gait training in stroke rehabilitation, and to determine predicting factors of significant improvements in post-stroke patients.
- Trial name
- NCT05825144
- Testing
- Robotic exoskeleton-assisted gait rehabilitation, Conventional rehabilitation
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- Taichung Veterans General Hospital
Stroke
Effects of Upper Limb Motor and Robotic Training Over Neuroplasticity and Function Capacity
The purpose of this study is to evaluate and compare the effects of upper limb training with Induced Constraint Therapy (ICT) or robotic therapy. No placebo therapy is used.
- Trial name
- NARLE1 (NCT02700061)
- Testing
- Robotic occupational therapy, Induced Constraint Therapy - ICT
- Where
- Brazil
- Volunteers
- 51 people
- Sponsor
- University of Sao Paulo General Hospital
Stroke, Stroke Sequelae
The StrokeCog Study: Cognitive Rehabilitation Intervention in Stroke
This study aims to progress to the next stage of feasibility testing, by conducting a pilot randomised controlled study with consecutive stroke patients who have mild to moderate cognitive impairment following stroke.
- Conditions
- Stroke, Stroke Sequelae, Cognitive Impairment
- Trial name
- StrokeCog-R (NCT06021470)
- Testing
- Cognitive rehabilitation intervention
- Volunteers
- 64 people
- Sponsor
- Royal College of Surgeons, Ireland
Brain Injuries, Disorder of Consciousness
Long Term Effects of Soft Splints on Stroke Patients and Patients With Disorders of Consciousness
The purpose of this study is to assess the effects on upper limb spasticity of soft splints worn during three weeks three hours a day by patients with stroke or disorders of consciousness.
- Conditions
- Brain Injuries, Disorder of Consciousness, Stroke, Spasticity as Sequela of Stroke
- Trial name
- NCT03008486
- Testing
- Real soft splint (6 cm)
- Where
- Belgium
- Volunteers
- 12 people
- Sponsor
- Géraldine Martens
Ischemic Stroke
Stem Cell Infusion in the Treatment of Patients with Neurological Sequelae After Ischemic Stroke
This trial is to investigate the safety and potential therapeutic efficacy of allogeneic administration of umbilical cord-derived MSCs (UC-MSCs) in combination with standard neurological complications after ischemic stroke…
- Trial name
- NCT05292625
- Testing
- UC-MSC infusion via intravenous route, UC-MSC infusion via intrathecal route, standard stroke treatment and rehabilitation therapy
- Where
- Vietnam
- Volunteers
- 48 people
- Sponsor
- Vinmec Research Institute of Stem Cell and Gene Technology
Arrhythmia, Atrial Fibrillation
Arterial Embolism After Catheter Ablation of Atrial Fibrillation. ATRIAL FIBRILLATION
The EMBOL-AF is a multicenter, international, observational study designed as a retrospective registry that will investigate the characteristics of systemic arterial embolic events after treatment of atrial fibrillation by…
- Conditions
- Arrhythmia, Atrial Fibrillation, Ablation, Stroke, Acute
- Trial name
- EMBOL-AF (NCT06134739)
- Testing
- No intervention.
- Where
- Spain
- Volunteers
- 500 people
- Sponsor
- Hospital Universitario La Paz
Stroke Sequelae, Gait, Hemiplegic
ACTive Exoskeleton for Unilaterally-Assisted Locomotion (ACTUAL)
Walking difficulties are common symptoms after stroke, significantly reducing quality of life. Walking recovery is therefore one of the main priorities of rehabilitation.
- Trial name
- ACTUAL (NCT06061601)
- Testing
- Exoskeleton stroke group
- Where
- Italy
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Chronic Stroke, Spasticity as Sequela of Stroke
Effects of EMG-driven Robot-assisted Therapy for the Distal Upper Limb Motor Function in the Chronic Stroke Patients With Botox Injections
Over fifty percent of stroke patients experience chronic arm hand performance problems, compromising independence in daily life activities and quality of life.
- Conditions
- Chronic Stroke, Spasticity as Sequela of Stroke, Robotic Rehabilitation
- Trial name
- NCT04502264
- Testing
- Hand of Hope, Botulinum toxin type A injection
- Where
- Taiwan
- Volunteers
- 24 people
- Sponsor
- Cheng-Hsin General Hospital
Stroke Sequelae
Resume Walking by an Interactive Mobile Robot of Rehabilitation After Vascular Stroke (Cerebral Vascular Stroke) in Combination With Traditional Reeducation
The recovery of a balance and gait is a primary objective for geriatric, neurological or orthopedic rehabilitation. Since the 80s, many walking robots were proposed.
- Trial name
- ROBOK2 (NCT03686280)
- Testing
- Clinical evaluation, Intervention - with Robot, Intervention - without Robot
- Where
- 2 sites in France
- Volunteers
- 37 people
- Sponsor
- Rennes University Hospital
Stroke Sequelae
Effect of Air Splints on Sensoriomotor Disturbances of the Affected Upper Extremity and Trunk Control in the Adult Post-stroke Patient
Objective: Sensory impairment in the affected upper limb occurs in approximately 50% of post-stroke patients and negatively impacts functional capacity and quality of life.
- Trial name
- NCT07029061
- Testing
- Air splints
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Alfonso X El Sabio University