Clinical trials: Seronegative Arthritis
Seronegative Spondyloarthropathies
Combination Disease-Modifying Antirheumatic Drugs (DMARDs) Versus Sulfasalazine in Inflammatory Back Pain
Till now no drug has been conclusively shown to affect the natural course of the inflammatory back ache in seronegative spondylarthropathies.
- Trial name
- NCT01040195
- Testing
- Methotrexate, Hydroxychloroquine
- Where
- India
- Volunteers
- 33 people
- Sponsor
- Sanjay Gandhi Postgraduate Institute of Medical Sciences
Spondyloarthropathies
The Characterization of Small Bowel and Colonic Involvement in Patients With Seronegative Spondyloarthritides
Up to 60% of patients with Seronegative Spondyloarthritides have inflammation in the colon or ileum. This is usually asymptomatic, but in 5 to 10% of patients with SA, Frank IBD will develop.
- Trial name
- SPONDILENDO (NCT00768950)
- Testing
- Capsule endoscopy examination, Colonoscopy
- Where
- Romania
- Volunteers
- 65 people
- Sponsor
- Carol Davila University of Medicine and Pharmacy
Spondylarthropathies
Seronegative Oligoarthritis of the Knee Study (SOKS)
The aim of this study is to establish the efficacy and duration of effect of intra-articular (IA) infliximab vs intravenous infliximab vs current standard care (IA steroid injections) in seronegative oligoarthritis.
- Trial name
- SOKS (NCT01216631)
- Testing
- methylprednisolone, Infliximab
- Where
- United Kingdom
- Volunteers
- 1 people
- Sponsor
- University of Leeds
Rheumatoid Arthritis
Cardiovascular Risk Factors in Rheumatoid Arthritis Patients ( Comparison Between Seronegative and Seropositive Cases )
The goal of this observational study is to learn about the long-term effects rheumatoid arthritis (RA) on cardiovascular system.
- Trial name
- NCT06738264
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
Juvenile Idiopathic Arthritis, Rheumatoid Arthritis
Medical Follow-up of New Cases of Polyarthritis in Children and Young Adults
Population: Juvenile idiopathic arthritis (JIA), rheumatoid arthritis (RA) and seronegative / psoriatic / undifferentiated arthritis (UA), systemic lupus erythematosus (SLE) or diffuse systemic sclerosis dSS).
- Conditions
- Juvenile Idiopathic Arthritis, Rheumatoid Arthritis, Psoriatic Arthritis, Systemic Lupus Erythematosus
- Trial name
- NCT07000916
- Where
- Belgium
- Volunteers
- 1,000 people
- Sponsor
- Université Catholique de Louvain
Arthritis
Safety and Efficacy of Gardasil in Females With Juvenile Idiopathic Arthritis (JIA)/Seronegative Arthritis
The purpose of this research study is to see if patients with juvenile idiopathic arthritis or seronegative arthritis (and related conditions) mount protective immune responses to the human papillomavirus (HPV) vaccine called…
- Trial name
- CHASE (NCT00573651)
- Testing
- Blood Draws for Serum Titers
- Where
- 4 sites in United States
- Volunteers
- 43 people
- Sponsor
- University Hospitals Cleveland Medical Center
Inflammatory Arthritis
Allied Health in Rheumatology Triage Project
There is accumulating evidence that early treatment leads to better outcomes for patients with inflammatory arthritis (IA). Triage, which is the process of identifying the urgency of a patient's disease state efficiently and…
- Trial name
- AHRT (NCT02465879)
- Testing
- Therapist Triage
- Volunteers
- 295 people
- Sponsor
- Sunnybrook Health Sciences Centre
Psoriatic Arthritis, Rheumatoid Arthritis
Optimization of Psoriatic and Seronegative Rheumatoid Arthritis Patients Selection and Treatment Outcomes of Biologic Therapies.
Different classes of biological targeted therapies (b-DMARDs) are available for psoriatic arthritis (PsA) and seronegative rheumatoid arthritis (RA) (TNF inhibitors, anti-IL23, anti-IL17).
- Trial name
- NCT05767814
- Testing
- Phenotyping of synovial immune and stromal cells
- Where
- 2 sites in Italy, United Kingdom
- Volunteers
- 135 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Rheumatoid Arthritis
Role of CTHRC1 in Diagnosis of Rheumatoid Arthritis
to detect the role of CTHRC1 biomarker in diagnosis of rheumatoid arthritis and To correlate other well-established rheumatoid arthritis markers (RF\& anti-ccp) and CTHRC1 level to see if CTHRC1 can act as a dependent or…
- Trial name
- NCT04092244
- Testing
- CTHRC1 biomarker
- Volunteers
- 90 people
- Sponsor
- Assiut University
Rheumatoid Arthritis
Serum Anti-PCOLCE as Novel Diagnostic Biomarker in Rheumatoid Arthritis With Emphasis on Seronegative Patients.
Rheumatoid arthritis (RA) is a chronic autoimmune disease that primarily affects synovial joints, leading to pain, swelling, and progressive joint damage. Early diagnosis is critical to prevent irreversible disability.
- Trial name
- Anti-pcolce/RA (NCT07129837)
- Testing
- Clinical evaluation, disease activity and disability scoring, and laboratory testing including RF, anti-CCP, and serum anti-PCOLCE antibody measurement by ELISA.
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Assiut University
Rheumatoid Arthritis
Italian Registry of Arthritis on Biologic Therapy
The biologic drugs targeting TNFa, IL-6, IL-1, T cells, B cells have represented a fundamental discovery to treat rheumatic patients whose disease appears to be refractory to conventional therapy.
- Trial name
- GISEA (NCT01543594)
- Where
- Italy
- Volunteers
- 10,000 people
- Sponsor
- Gruppo Italiano Studio Early Arthritis
Spondyloarthropathy, Fibromyalgia
Ultrasound Assessment of Entheseal Sites in Patients with Seronegative Spondyloarthropathy with or Without Fibromyalgia
Seronegative spondyloarthropathies are a family of joint disorders that classically include ankylosing spondylitis (AS), psoriatic arthritis (PsA), inflammatory bowel disease (IBD) associated arthritis, reactive arthritis…
- Trial name
- NCT06495866
- Testing
- ultrasound
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Sohag University
SpA, PsA
Closing the Gap in Care in Seronegative Inflammatory Arthritis
Rheumatologists treating patients with seronegative arthritis will be randomized to treat their patients to a target or to treat their patients under their usual standard of care.
- Trial name
- Metrix II (NCT01749618)
- Testing
- Education and Feedback
- Where
- 9 sites in Canada
- Volunteers
- 40 people
- Sponsor
- Pope Research Corporation
Ankylosing Spondylitis, Spondylarthritis
Ankylosing Spondylitis and Spondyloarthritis Evaluation Tool Study
This study aims to test whether a new instrument (questionnaire) is useful for identifying patients with ankylosing spondylitis.
- Trial name
- NCT01302730
- Where
- United States
- Volunteers
- 490 people
- Sponsor
- Stanford University