Clinical trials: Seroquel XR
Schizophrenia
Seroquel XR in Adults With Schizophrenia
The purpose of this study is to evaluate the efficacy of Seroquel XR in schizophrenia patients with acute worsening symptoms. Consequently, to assess whether the study drug is safe and acceptable on the daily dose basis, orally…
- Trial name
- NCT00852631
- Testing
- Quetiapine fumarate (Seroquel)
- Where
- 3 sites in Thailand
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Major Depressive Disorder, Insomnia
Quetiapine Extended Release (XR) for the Treatment of Menopausal Depression
The study was designed to examine the efficacy and tolerability of quetiapine XR for the treatment of women who suffer from depression in the context of the menopausal transition and postmenopausal years.
- Conditions
- Major Depressive Disorder, Insomnia, Hot Flashes
- Trial name
- NCT00723970
- Testing
- Quetiapine Extended Release
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- McMaster University
Depression
Positron Emission Tomography (PET) Study With [11C]Raclopride to Determine Central D2 Dopamine Occupancy of SEROQUEL
The aim of this study is to relate pharmacokinetics of two different formulations of quetiapine to PET measured receptor occupancy in the brains of healthy subjects.
- Trial name
- PET (NCT00832221)
- Testing
- SEROQUEL XR (quetiapine), SEROQUEL IR (quetiapine), radioligand [11C]raclopride
- Where
- Sweden
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Abnormal Mental State, Schizophrenia
Effects of 'Seroquel-XR' on the Improvement of Neurocognitive Function in People At-risk Mental States(ARMS)
The primary objective of this study is to assess the effects of 'Seroquel-XR' on the verbal learning ability in people with at-risk mental state (ARMS) over a 12 week period.
- Trial name
- ES-ARMS (NCT01250847)
- Testing
- Quetiapine(Seroquel-XR) 50~800mg a day
- Where
- 2 sites in South Korea
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Severance Hospital
Generalized Anxiety Disorder, Seroquel XR
Generalized Anxiety and Seroquel
The 12 week clinical trial of Seroquel in Generalized Anxiety Disorder (GAD) patients will be combined with fMRI experiments.
- Trial name
- GAD (NCT01066143)
- Testing
- Seroquel XR
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Major Depressive Disorder
Effects of Seroquel XR on Sleep Architecture in Patients With Major Depressive Disorder
In this study, patients with major depressive disorder (MDD) who have insomnia symptom are treated with Seroquel XR in an open-label manner for a 4-week period with repeated measurements of insomnia symptoms and sleep parameters…
- Trial name
- NCT01189318
- Testing
- Quetiapine Fumarate Extended Release
- Where
- South Korea
- Volunteers
- healthy volunteers welcome
- Sponsor
- Ewha Womans University
Healthy Volunteers
Quetiapine Fumarate Immediate Release (IR) Versus Extended Release (XR) Dose Escalation Comparison
This study will compare the tolerability of Quetiapine Fumarate immediate release formulation and Quetiapine Fumarate extended release formulation during initial dose escalation in healthy volunteers.
- Trial name
- NCT00702676
- Testing
- Quetiapine Fumarate
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- AstraZeneca