Clinical trials: Serrated Polyp
Colon Adenoma, Colorectal Carcinoma
NBI Versus White Light Endoscopy for Optical Characterization of Neoplastic Polyps in the Colorectum
Adenomas, serrated adenomas and hyperplastic polyps are polypoid lesion in the colorectum. At the present moment, all polyps should be resected endoscopically, although only adenomas and serrated adenomas, but not hyperplastic…
- Conditions
- Colon Adenoma, Colorectal Carcinoma, Hyperplastic Polyp, Serrated Adenoma
- Trial name
- ADOPTION II (NCT03679429)
- Testing
- NBI Function
- Where
- 3 sites in Germany
- Volunteers
- 370 people
- Sponsor
- Technical University of Munich
Polyps, Adenoma Colon
Computer Assisted Selection of Serrated Adenomas and Neoplastic Polyps - a New Clinical DRAft
The aim of the study is to develop a computer program which is able to classify different entities of colorectal polyps on the basis of optical polyp features.
- Conditions
- Polyps, Adenoma Colon, Automatic Judgement, Colonic Neoplasms
- Trial name
- CASSANDRA I (NCT03550625)
- Testing
- Computer program
- Volunteers
- 300 people
- Sponsor
- Technical University of Munich
Colonic Neoplasms, Colorectal Cancer
Molecular and Histological Characteristics of Serrated Lesions of the Colon
Different subtypes of serrated lesions have been recently described. Among them, both sessile serrated polyp/adenoma (SSP/A) and traditional serrated adenoma (TSA) could have malignant potential through the serrated pathway or…
- Conditions
- Colonic Neoplasms, Colorectal Cancer, Sessile Serrated Adenoma, Polyp of Colon
- Trial name
- SERRACOLON (NCT03089268)
- Testing
- Colonoscopy, Polypectomy or biopsy, Molecular analysis
- Where
- Spain
- Volunteers
- 700 people
- Sponsor
- Hospital Universitario La Fe
Sessile Serrated Adenoma
Prediction of Dysplasia Within Sessile Serrated Polyps Using Endoscopic Imaging; a Prospective Observational Study
Study of endoscopic imaging in the detection of dysplasia within serrated colonic lesions >= 8mm in size
- Trial name
- SERRESH (NCT03100552)
- Testing
- Endoscopic imaging
- Where
- Australia
- Volunteers
- 86 people
- Sponsor
- Western Sydney Local Health District
Adenoma, Colonoscopy
Effect of Two Colonoscopy AI Systems for Colon Polyp Detection
Computer-aided detection (CADe) systems have been actively researched for polyp detection in colonoscopy. The investigators aim to identify the effect of two CADe systems according to the system performance on false positive rate
- Conditions
- Adenoma, Colonoscopy, Sessile Serrated Adenoma
- Trial name
- NCT05089071
- Testing
- Assist by artificial intelligence system for colon polyp detection
- Where
- South Korea
- Volunteers
- 3,046 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Colorectal Neoplasm, Colorectal Cancer
Colorectal Cancer Screening Using Stool DNA-based SDC2 and SFRP2 Methylation Test in China
The primary objective is to determine sensitivity, specificity, positive predictive value and negative predictive value of a bi-target stool DNA testing (the methylation status of SDC2 and SFRP2) for colorectal cancer and…
- Conditions
- Colorectal Neoplasm, Colorectal Cancer, Adenomatous Polyps, Adenoma
- Trial name
- NCT04515082
- Testing
- Stool-based SDC2 and SFRP2 DNA methylation test, FIT
- Volunteers
- 4,800 people
- Sponsor
- Changhai Hospital
Colorectal Neoplasms, Adenoma Colon
Surveillance Intervals After Piecemeal Resection of Non-pedunculated Colorectal Lesions ≥20mm
Intensive endoscopic surveillance following piecemeal resection of non-pedunculated colorectal lesions (NPCL) ≥20 mm is the current standard of care, given the high recurrence rate of these lesions (15-30%).
- Conditions
- Colorectal Neoplasms, Adenoma Colon, Colonic Polyps, Serrated Adenoma
- Trial name
- NCT06791616
- Testing
- Colonoscopy
- Volunteers
- 746 people
- Sponsor
- Asociación Española de Gastroenterología
Sessile Serrated Adenoma, Colorectal Polyp
Assessing the Agreement Between Endoscopic and Histopathological Diagnosis of Colorectal Sessile Serrated Lesions.
The goal of this observational study was to assess the degree of agreement between the endoscopic and anatomopathological diagnosis of sessile serrated colorectal lesions in adult patients undergoing colonoscopy in Hospital…
- Conditions
- Sessile Serrated Adenoma, Colorectal Polyp, Adenoma Colon, Colorectal Cancer
- Trial name
- NCT06173297
- Where
- Brazil
- Volunteers
- 772 people, healthy volunteers welcome
- Sponsor
- Hospital Sirio-Libanes
Colorectal Neoplasms, Colonic Polyps
Clinical Validity Verification on Diagnostic Assistance for Presence and Severity of Colorectal Cancer and Polyps Using Artificial Intelligence-based Medical Device Software Endoscopic Imaging Assistance
This completed retrospective study evaluated the clinical performance of ENAD-CADx-01, an artificial intelligence-based medical device software intended to assist healthcare professionals in characterizing colorectal lesions in…
- Conditions
- Colorectal Neoplasms, Colonic Polyps, Hyperplastic Polyps, Sessile Serrated Lesions
- Trial name
- NCT07744607
- Where
- South Korea
- Volunteers
- 1,114 people
- Sponsor
- Ainex Corporation