Clinical trials: Serum Iron
Iron-deficiency
How Does a Synbiotic Supplement Affect Iron Status During Iron Repletion in Iron Depleted Female Athletes?
Iron deficiency (ID) affects ~30% of female athletes, and its consequences are highly relevant to athletic performance. Poor iron (Fe) uptake remains a major factor in the development of ID.
- Trial name
- NCT03793959
- Testing
- Synbiotic Supplement
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Marywood University
Iron Deficiency Without Anemia
Assessing the Immediate Increase in Serum Ferritin After Oral Iron Doses: an Experimental Study in Iron-deficient Women
Serum ferritin is a key indicator of body iron stores and is widely used in monitoring iron status. However, oral iron doses can acutely elevate SF levels, potentially biasing assessments of iron stores during supplementation.
- Trial name
- INFER 2 (NCT06851130)
- Testing
- ferrous sulfate 80 mg, ferrous sulfate 160 mg
- Where
- Switzerland
- Volunteers
- 120 people
- Sponsor
- Swiss Federal Institute of Technology
Hypoferritenemia Without Anemia (HWA), Iron Deficiency Without Anemia)
Hypoferritinemia Without Anemia Among Reproductive Age Females
The goal of this randomized controlled trial is to compare the treatment outcomes of oral iron supplementation (Group A) versus Intravenous (IV) iron supplementation (Group B) versus no treatment (Group C) on the serum ferritin…
- Trial name
- NCT06437080
- Testing
- Iron III Hydroxide Polymaltose Complex eq. to Elemental Iron, 100 mg, Ferric Carboxymaltose
- Where
- 4 sites in Pakistan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Akram Medical Complex
Myelodysplastic Syndromes, Transfusion Dependent Iron Overload
Efficacy and Safety of Deferasirox in Patients With Myelodysplastic Syndrome and Transfusion-dependent Iron Overload
The purpose of this study is to investigate the effects of iron chelation using deferasirox in low and INT-1 risk (referring to the international prognostic scoring system, IPSS) MDS patients who show signs of iron overload due…
- Trial name
- NCT00481143
- Testing
- ICL670/Deferasirox
- Where
- Germany
- Volunteers
- 63 people
- Sponsor
- Novartis Pharmaceuticals
Nutritional Status
Timing of Iron Supplementation in Very Low Birth Weight Infants
To examine if early iron supplementation (starting oral iron at 14 days of life) would improve the nutritional iron status(measured by serum ferritin) of very low birth weight infants at postnatal age of 60 days, when compared to…
- Trial name
- NCT00683527
- Testing
- Elemental iron
- Where
- India
- Volunteers
- 46 people
- Sponsor
- All India Institute of Medical Sciences
Healthy Women
Study of Serum Hepcidin Rate Variations During Menstrual Cycle
Hepcidin is the major hormone regulating Iron Metabolism. In a normal organism decrease iron stock causes a decrease in hepcidin synthesis thus promoting intestinal absorption of iron.
- Trial name
- HEPMEN (NCT01764412)
- Where
- 4 sites in France
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- Rennes University Hospital
Iron Overload
Efficacy and Safety of Oral Deferasirox (20 mg/kg/d) in Pts 3 to 6 Months After Allogeneic Hematopoietic Cell Transplantation Who Present With Iron Overload
The purpose of this study is to investigate the effects of iron chelation using deferasirox in patients who show signs of iron overload after an allogeneic stem cell transplantation The iron overload must be due to blood…
- Trial name
- NCT00654589
- Testing
- Deferasirox
- Where
- Germany
- Volunteers
- 75 people
- Sponsor
- Novartis Pharmaceuticals
Anemia, Anemia, Iron Deficiency
SpHb Perioperatively
This study's goal is to establish SpHb threshold values that can help health care provider sort out which patients would potentially benefit from central laboratory Hb testing pre-operatively and who would likely not.
- Trial name
- NCT04391517
- Testing
- SpHb measurement
- Where
- Austria
- Volunteers
- 1,284 people
- Sponsor
- Medical University of Graz
Iron Deficiency (Without Anemia)
Hepcidin After Intravenous Iron Treatment
The aim of this study is to investigate the hepcidin hormone response after intravenous iron administration.
- Trial name
- NCT06264687
- Volunteers
- 10 people
- Sponsor
- Pierre-Alexandre Krayenbühl
Anemia, Unexplained Anemia (UAE)
Trial To Evaluate the Efficacy of Intravenous Iron in Older Adults With Unexplained Anemia
The purpose of this study is to determine whether treatment of unexplained anemia in older adults with a short course of weekly intravenous iron infusions can improve physical activity and therefore quality of life.
- Trial name
- NCT01309659
- Testing
- iron sucrose
- Where
- 5 sites in United States
- Volunteers
- 19 people
- Sponsor
- Duke University
Iron Deficiency Anemia in Pregnancy
Comparing Two Intravenous Iron Treatments for Anemia in Kurdish Pregnant Women
The goal of this clinical trial is to compare two types of intravenous (IV) iron-Ferric Carboxymaltose (FCM) and Iron Sucrose (IS)-to learn which one works better to treat iron deficiency anemia in pregnant women who have a clear…
- Trial name
- NCT07721519
- Testing
- Intravenous Ferric Carboxymaltose (FCM), Iron Sucrose (IS) Infusion
- Volunteers
- 400 people
- Sponsor
- Hawler Medical University
Anemia, Iron Deficiency
Serum Hepcidin Immunoassay - Laboratory to Marketplace
This is a single center, prospective, observational study to demonstrate the clinical validity of the Intrinsic LifeSciences (ILS) Intrinsic Hepcidin IDx™ Test in the diagnosis and management of iron deficiency (ID) in…
- Trial name
- NCT03310736
- Testing
- Intrinsic Hepcidin IDx™ Test
- Where
- United States
- Volunteers
- 494 people, healthy volunteers welcome
- Sponsor
- Intrinsic LifeSciences, LLC
Chronic Renal Failure
Does Intravenous Iron Therapy Decrease Serum Phosphorous Levels?
Intravenous iron therapy is common and effective, with few side effects. Two formulations are used, venofer or iron sucrose and ferrlecit, or ferric gluconate.
- Trial name
- NCT02420119
- Testing
- non interventional
- Where
- Israel
- Volunteers
- 53 people
- Sponsor
- Frieda Wolf
Iron Deficiency (Without Anemia)
Assessing the Immediate Increase in Serum Ferritin After Oral Iron Doses
Serum ferritin is a key indicator of body iron stores and is widely used in monitoring iron status. However, oral iron doses can acutely elevate SF levels, potentially biasing assessments of iron stores during supplementation.
- Trial name
- NCT06657677
- Testing
- 40mg oral iron dosing, 100mg oral iron dosing, 180mg oral iron dosing
- Where
- 2 sites in Switzerland
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Jessica Rigutto
Cystic Fibrosis
Biomarkers of Iron Homeostasis and Responses to Cystic Fibrosis Pulmonary Exacerbation (CFPE) Treatment
The goal of this study is to identify chemical compounds in the blood and sputum (i.e., biomarkers) that are associated with objective measurements of health status in patients with cystic fibrosis (CF).
- Trial name
- NCT02188758
- Testing
- Adults - CFPE Treatment
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Dartmouth-Hitchcock Medical Center