Clinical trials: Service Evaluation, open to volunteers
Multimorbidity, Integrated Care
TimelyCare - A Proactive Primary Care Model: Delivering the Right Care at the Right Time for Individuals at Risk of High Care Consumption
Healthcare systems face persistent challenges in providing coordinated, proactive care for individuals with complex health needs, resulting in high vulnerability to fragmented care, acute clinical deterioration, and frequent…
- Conditions
- Multimorbidity, Integrated Care, Primary Care Patients With Chronic Conditions, Coordination, Administrative
- Trial name
- NCT07899723
- Testing
- Timely Care,
- Where
- Sweden
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Linnaeus University
Surgery, Geriatric Assessment
Implementation Pilot of Preoperative CGA Before Major Surgery
The goal of this clinical trial is to test whether a new implementation package can help older adults prepare for major surgery.
- Conditions
- Surgery, Geriatric Assessment, Health Services Research, Implementation Science
- Trial name
- NCT06184724
- Testing
- Implementation Package for CGA, Routine Clinical Care
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Risk of Dementia, Dementia
Development and Empirical Evaluation of a Brief Lifestyle Intervention for Older Adults at Risk of Dementia Within an Integrated Medical-Preventive Grid-Based Service Model
Lifestyle factors are among the most important modifiable risk factors for dementia, and primary prevention through lifestyle interventions is considered the most cost-effective approach to reducing the incidence of dementia.
- Trial name
- NCT07831616
- Testing
- Brief lifestyle intervention
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Fujian Medical University
Elder Abuse, Self-Neglect
Replication and Evaluation of the RISE-APS Model In New Contexts
The goal of this study is to learn if the intervention, RISE (in partnership with APS), can be implemented in different contexts and if this RISE-APS model works in supporting older adults who are at risk of or experiencing some…
- Trial name
- NCT07368257
- Testing
- RISE, APS
- Where
- 4 sites in United States
- Volunteers
- 300 people
- Sponsor
- RISE Collaborative
Stunting, Gender Equality
Evaluation of REACTS-IN, an Intervention to Improve Nutrition, Hygiene, and Sexual and Reproductive Health Services
This is an independent evaluation of World VIsion's 7-year quasi-experimental intervention to improve nutrition, nutrition-related rights and gender equality for women, adolescent girls, and children under five years of age in…
- Conditions
- Stunting, Gender Equality, Acceptability of Health Care, Diet; Deficiency
- Trial name
- REACTS-IN (NCT06362837)
- Testing
- Education intervention on nutrition, gender equity, WASH, sexual and reproductive health rights, school-based iron-folic acid supplement program, Health service training on equitable access to nutrition, health, and sexual and reproductive services
- Where
- 3 sites in Bangladesh, Kenya and 1 more
- Volunteers
- 13,500 people
- Sponsor
- McGill University
Frailty, Aging
Autonomous At Home with Occupational Therapy Support and Assistive Devices
The aim of the AUDACE study is to evaluate the 'Bien chez Moi 2.0' programme, to assess how, for whom and why do assistive devices, integrated with occupational therapy support, enable older people to remain at home, and under…
- Conditions
- Frailty, Aging, Home Care Services
- Trial name
- AUDACE (NCT06819982)
- Testing
- BCM2.0
- Where
- Belgium
- Volunteers
- 3,900 people
- Sponsor
- Université Catholique de Louvain
Diarrhea, Respiratory Tract Infections (RTI)
Impact Evaluation of Accelerating Climate-Resilient Water, Sanitation and Hygiene Services for Schools and Healthcare Facilities in Karamoja
Karamoja, in north-eastern Uganda, is among the most water-insecure regions in sub-Saharan Africa. Only 24 per cent of households can access the WHO-recommended 20 litres of water per person per day.
- Conditions
- Diarrhea, Respiratory Tract Infections (RTI), Menstrual Hygiene, Absenteeism
- Trial name
- NCT07823231
- Testing
- Climate-resilient school WASH infrastructure package, WASH and menstrual health capacity building and social and behaviour change package
- Where
- Uganda
- Volunteers
- 16,380 people, healthy volunteers welcome
- Sponsor
- Elijah Kipchumba
Mild Traumatic Brain Injury, Alexithymia
Clinical Trial Comparing the Efficacy of Two Teletherapy Programs at Improving Psychological Health in People With Brain Injury
The purpose of the study is to test two different training programs to find out which is better at helping people with a concussion or mild TBI (mTBI) improve their emotional health and well-being.
- Trial name
- NCT07436754
- Testing
- Program 1, Program 2
- Where
- 3 sites in United States
- Volunteers
- 300 people
- Sponsor
- Hackensack Meridian Health
Pharmacogenetics, Depression - Major Depressive Disorder
An Evaluation of the Impact of Pharmacist Comprehensive Medication Management With Pharmacogenomic Results to Improve Depression Outcomes in Community Pharmacies.
The goal of this prospective, randomized clinical trial is to learn whether pharmacogenomic (PGx)-guided comprehensive medication management delivered by pharmacists in community pharmacies will improve antidepressant treatment…
- Conditions
- Pharmacogenetics, Depression - Major Depressive Disorder, Pharmacogenomic Drug Interaction, Community Pharmacy Services
- Trial name
- COMPASS-PGx (NCT07373470)
- Testing
- Comprehensive medication management with PGx testing results, Usual Care
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- University of Pittsburgh
Prostate Cancer
Improving Engagement From Underserved Communities With Prostate Cancer Genetics Services
Earlier work explored barriers and facilitators to accessing prostate cancer screening, particularly in underserved communities, and provided valuable insights to build upon.
- Trial name
- INCLUDE PC (NCT07407686)
- Testing
- Surveys, Semi-structured interviews and focus groups
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Royal Marsden NHS Foundation Trust
Community Pharmacy Services
Evaluation of the Effect of Consensus-based Protocols for the Treatment of Minor Ailments
Minor ailments are common, self-limited conditions unrelated to the patient's underlying health problems or adverse effects of their current medications.
- Trial name
- NCT06378099
- Testing
- Patient guided and followed by the pharmacist
- Where
- Colombia
- Volunteers
- 900 people
- Sponsor
- Universidad de Antioquia
Rhabdomyolysis, Virtual Reality
Evaluation of the Effectiveness of Using Virtual Reality Glasses in Prehospital Intervention Training for Crush Syndrome
This research is a randomized controlled study designed to develop and evaluate the effectiveness of a video-based virtual reality (VR) simulation for prehospital intervention training of crush syndrome for paramedic students.
- Conditions
- Rhabdomyolysis, Virtual Reality, Emergency Medical Services, Disaster Medicine
- Trial name
- NCT07361835
- Testing
- Virtual reality-based crush syndrome training, Traditional theoretical lecture
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Ege University
Prostate Cancer, Risk Assessment
PROstate Cancer Risk Calculator for ACTionable Clinical Decision-making in Nigeria
This study is a pilot trial that builds on findings from the validation of prostate cancer risk calculators in Nigerian men. The goal of the overall study is to improve the early detection of prostate cancer in a high-risk…
- Conditions
- Prostate Cancer, Risk Assessment, Clinical Decision Support Systems, Predictive Value of Tests
- Trial name
- PROACT (NCT07733440)
- Testing
- (a) Training and (b) Supported risk assessment
- Where
- Nigeria
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Ahmadu Bello University
Thyroid Nodule (Benign), Graves Disease
Thyroid Artery Goitre Embolization Trial A Pilot Study Investigating Thyroid Artery Embolisation as a Treatment for Large Thyroid Nodules
Large non-cancerous thyroid nodules (lumps in the thyroid gland) can cause pressure or discomfort in the neck or cosmetic issues. The standard treatment options include radiofrequency ablation, radioactive iodine, and surgery.
- Conditions
- Thyroid Nodule (Benign), Graves Disease, Goitre
- Trial name
- TArGET (NCT07046546)
- Testing
- Thyroid artery embolization
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- Royal Berkshire NHS Foundation Trust
Stillbirth
The Tommy's National Rainbow Clinic Study
The death of a baby before or shortly after birth affects approximately 1 in every 250 pregnancies in the UK meaning that over 4,000 parents experience the death of a baby each year in the UK.
- Trial name
- NCT04393259
- Testing
- Rainbow Clinic Model of Antenatal Care
- Where
- United Kingdom
- Volunteers
- 500 people
- Sponsor
- University of Manchester
Chest Pain, Acute Coronary Syndrome
AI-Assisted Interpretation of Cardiac CT in the Emergency Department
" This prospective, pragmatic, randomized controlled trial is designed to evaluate the impact of an artificial intelligence (AI)-based coronary computed tomography angiography (CCTA) interpretation tool (Angiomics) on emergency…
- Conditions
- Chest Pain, Acute Coronary Syndrome, Coronary Artery Disease
- Trial name
- NCT07235657
- Testing
- Angiomics AI-based Coronary CT Interpretation Tool, Standard CCTA Interpretation without AI
- Where
- South Korea
- Volunteers
- 530 people
- Sponsor
- Yonsei University
Problem Behavior, Developmental Delay
Problem Behavior Assessment and Intervention in IDEA Part C Services
The purpose of this study is to evaluate the effect of function-based assessment and intervention to reduce problem behavior in children with developmental disability or delay in the context of IDEA Part C services.
- Conditions
- Problem Behavior, Developmental Delay, Developmental Disability
- Trial name
- NCT06771284
- Testing
- Function-based assessment and intervention
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Las Vegas
Chronic Diseases in Children, Chronic Diseases in Adolescence
Transmural Care for Chronically Ill Children: Scientific Guidance and Evaluation of Pilot Projects
The goal of this Realist Evaluation is to evaluate the implementation of pilot projects for transmural care in chronically ill children.
- Conditions
- Chronic Diseases in Children, Chronic Diseases in Adolescence, Health Personnel, Parents
- Trial name
- PETRACA (NCT06679595)
- Testing
- Pilot project paediatric transmural care
- Where
- 11 sites in Belgium
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Health Services Research
Study of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ICP-538 in Healthy Subjects
This is a Randomized, Double-Blind, Placebo-Controlled, Single and Multiple Ascending Dose Phase I Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ICP-538 in Healthy Subjects
- Trial name
- NCT07535099
- Testing
- ICP-538 Tablets
- Where
- China
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Beijing InnoCare Pharma Tech Co., Ltd.
Abdominal Pain (AP), Acute Abdomen
Emergency Medicine Evaluation for Acute Abdominal Pain - a Pragmatic Randomized Trial
The goal of this clinical trial is to learn whether initial assessment by a physician specializing in emergency medicine can improve the care of adults who come to the emergency department with acute abdominal pain or another…
- Conditions
- Abdominal Pain (AP), Acute Abdomen, Acute Abdominal Pain, Abdomen, Acute
- Trial name
- EMERGE-Abdomen (NCT07815795)
- Testing
- Emergency Medicine Initial Assessment, Standard Surgical Assessment
- Where
- Norway
- Volunteers
- 440 people
- Sponsor
- Haukeland University Hospital