Clinical trials: Severe Acute Malnutrition
Severe Acute Malnutrition
Synbiotics for the Management of Malnutrition (Children)
In this study, dose related effect of synbiotics on the blood indices of severely acute malnourished (SAM) children (6-59 months) was carried out in hospitalized setting.
- Trial name
- NCT06722404
- Testing
- Standard therapeutic foods, Therapeutic foods plus Synbiotics
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- University of Veterinary and Animal Sciences, Lahore - Pakistan
Acute Malnutrition, Severe, Malnutrition, Child
Increasing the Coverage of Severe Acute Malnutrition (SAM) Treatment in Ethiopia
The R-SWITCH intervention aims to address the low coverage of treatment for severe wasting (SAM) by leveraging existing community groups to deliver an integrated package focused on prevention, screening, referral, and treatment…
- Conditions
- Acute Malnutrition, Severe, Malnutrition, Child, Wasting
- Trial name
- R-SWITCH (NCT06380504)
- Testing
- R-SWITCH integrated intervention package
- Where
- Ethiopia
- Volunteers
- 1,080 people, healthy volunteers welcome
- Sponsor
- International Food Policy Research Institute
Kwashiorkor, Marasmus
Effectiveness of Oral Albendazole in the Treatment of Severe Acute Malnutrition
The benefit of anti-worm therapy as part of the case management of severe acute malnutrition (SAM) in the outpatient setting has not previously been studied.
- Trial name
- NCT01395381
- Testing
- Albendazole
- Where
- Malawi
- Sponsor
- Washington University School of Medicine
Severe Acute Malnutrition, Severe Wasting
Soy-Ready to Use Therapeutic Food (RUTF) in Severely Malnourished Children
SAM defined by having weight-for-height (WH) less than - 3 Z score or bi-pedal nutritional edema is an important cause of death in children globally including Bangladesh.
- Conditions
- Severe Acute Malnutrition, Severe Wasting, Community Based Nutritional Management
- Trial name
- NCT01634009
- Testing
- Soy-based RUTF (in double blind design)
- Where
- Bangladesh
- Volunteers
- 260 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
End-stage Renal Disease, Malnutrition; Protein
Impact of IDPN on Nutrition Markers in Patients Receiving ICHD
Evaluate the impact of intradialytic parenteral nutrition (IDPN) compounded with Clinisol, Prosol, and/or Clinolipid on albumin levels and weight in patients with end-stage renal disease (ESRD) undergoing in-center hemodialysis.
- Trial name
- NCT05439174
- Testing
- Intradialytic Parenteral Nutrition
- Where
- United States
- Volunteers
- 1,200 people
- Sponsor
- Patient Care America
Acute Malnutrition in Infancy (Disorder)
Optimizing Acute Malnutrition Management in Children Aged 6 to 59 Months in Niger (OptIMA Niger)
Acute malnutrition (AM) is a continuum condition, arbitrarily divided into severe and moderate categories (SAM, MAM) which are managed separately, with programs overseen by different agencies with different products and supply…
- Trial name
- NCT04698070
- Testing
- Nutritional Strategy - OptiMA, Nutritional Strategy - ComPAS, National nutritional Strategy (Niger)
- Where
- 4 sites in Niger
- Volunteers
- 2,304 people
- Sponsor
- Alliance for International Medical Action
Severe Acute Malnutrition
RECIPE BASED F100 INTERVENTION FOR NUTRITIONAL EFFICACY IN SAM (REFINE-SAM )
This open-label randomized controlled trial evaluates the efficacy and safety of multiple formulations of the F-100 therapeutic feed during the rehabilitation phase among children aged 6-59 months with SAM, in comparison to…
- Trial name
- REFINE-SAM (NCT07130877)
- Testing
- WHO F100, WHO RECIPE BASED F100
- Where
- 2 sites in Pakistan
- Volunteers
- 114 people
- Sponsor
- Children's Hospital and Institute of Child Health, Multan
Severe Acute Malnutrition, Cognitive Impairment
Intervening to Repair Cognitive and Behavioural Problems in Adults Exposed to Childhood Malnutrition
Globally, in 2011, 52 million children under 5 years old suffered from acute malnutrition, and a further 165 million children showed evidence of chronic undernutrition or stunting.
- Conditions
- Severe Acute Malnutrition, Cognitive Impairment, Emotional Disturbances
- Trial name
- NCT04053218
- Testing
- Exercise plus omega-3 supplement
- Where
- Jamaica
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The University of The West Indies
Intestinal Malabsorption, Critical Illness
Protein-bound Versus Free Amino Acid Nutrition During INtestinal Malabsorption in Critical Illness
In the current study, we willquantitate the difference in digestion and absorption kinetics of dietary whole protein versus free amino acids in vivo in critically ill patients admitted to the intensive care unit suffering from…
- Conditions
- Intestinal Malabsorption, Critical Illness, Protein Malnutrition
- Trial name
- PANINI (NCT04791774)
- Testing
- Milk protein (food grade protein), Fee amino acids (food grade amino acids)
- Where
- Netherlands
- Volunteers
- 16 people
- Sponsor
- Maastricht University Medical Center
Malnutrition; Protein
Essential Connections: Hospital to Community Impacting Malnutrition Outcomes in Older Adults
Meal provision organizations, whether they provide meals within the home or in congregate centers, provide an excellent opportunity to address malnutrition by providing nutrition care and meals to those who are most vulnerable.
- Trial name
- NCT05893446
- Testing
- Nutrition care by RDN, medical nutrition therapy -stepped wedge cluster-randomized trial design. Everyone gets the intervention so no arms.
- Volunteers
- 1,120 people
- Sponsor
- Academy of Nutrition and Dietetics
Acute Diarrhea, Severe Acute Malnutrition
IL6&8 in Malnourished Children With Acute Diarrhea
Cytokines, such as IL-6 and IL-8 can be used as markers of acute infections, including acute gastroenteritis. However, there have been no previous studies on the levels of IL-6 and IL-8 in malnourished children with acute…
- Conditions
- Acute Diarrhea, Severe Acute Malnutrition, Acute Gastroenteritis
- Trial name
- NCT05183789
- Testing
- Evaluation of serum levels of IL-6 and IL-8
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Sohag University
Child Malnutrition, Malnutrition in Children
Emollient Therapy for Severe Acute Malnutrition
The investigators hypothesize that the absorption of topically applied EFA-containing emollient (SSO) into the skin and thence into the bloodstream in children with SAM will improve skin barrier function and accelerate weight…
- Conditions
- Child Malnutrition, Malnutrition in Children, Malnutrition
- Trial name
- NCT02616289
- Testing
- Topical emollient (Sun Flower seed oil)
- Where
- Bangladesh
- Volunteers
- 212 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Severe Acute Malnutrition, Kwashiorkor
Effectiveness of Alternative Diets During the Stabilization Phase on Children With Complicated SAM
Severe acute malnutrition (SAM) is a life threatening condition and is defined by 1) a weight-for-height Z-score more than three standard deviations (SD) below the median based on the 2006 World Health Organization (WHO) growth…
- Conditions
- Severe Acute Malnutrition, Kwashiorkor, Nutritional Edema, Marasmus
- Trial name
- NCT05020847
- Testing
- Standard F75, Alternative F75 with CMV, Alternative F75 without CMV
- Where
- Burkina Faso
- Volunteers
- 297 people
- Sponsor
- University Ghent
Malnutrition; Protein, Cancer, Lung
Effect of NUTRICAN to Improve Nutritional Status in Cancer Patients
The goal of this clinical trial is to evaluate the efficacy oral nutrition supplement (ONS) in malnutrition/high risk malnutrition cancer patients. The main questions it aims to answer: 1.
- Conditions
- Malnutrition; Protein, Cancer, Lung, Cancer Cervix
- Trial name
- NCT06128694
- Testing
- NUTRICAN
- Where
- Indonesia
- Volunteers
- 108 people
- Sponsor
- Kalbe International Pte. Ltd
Acute Malnutrition in Childhood, Wasting
Treatment of Acute Malnutrition in Outpatient Care Services in Venezuela: a Prospective Cohort Research
The goal of this observational study is to compare the effectiveness, safety, and efficiency of the simplified protocol, which includes the following three modifications: a) use of a single treatment product (RUTF), b) reduced…
- Conditions
- Acute Malnutrition in Childhood, Wasting, Child Malnutrition
- Trial name
- NCT06287827
- Testing
- Simplified protocol, Standard protocol
- Where
- 4 sites in Venezuela
- Volunteers
- 299 people
- Sponsor
- UNICEF - Venezuela
Severe Acute Malnutrition
Performance of Mid-Upper Arm Circumference for Detection of Severe Acute Malnutrition in Indonesian Under-Fives
WHO recommends 11.5 cm as a cut-off point of Mid-Upper Arm Circumference (MUAC) to detect and/or diagnose severe acute malnutrition (SAM) in under-five.
- Trial name
- NCT06545240
- Testing
- Mid-upper arm circumference
- Where
- 2 sites in Indonesia
- Volunteers
- 421 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Clinically Severe Obesity, Metabolic Complications After Jejunoileal Bypass
Laparoscopic Revision of Jejunoileal Bypass to Gastric Bypass
This study objectives are the following. To describe the updated clinical presentation, indications, and multidisciplinary medical management of patients with a failed and/or complicated jejunoileal bypass (JIB).
- Conditions
- Clinically Severe Obesity, Metabolic Complications After Jejunoileal Bypass, Nutritional Complications After Jejunoileal Bypass, Obesity Recidivism
- Trial name
- JIB-to-RYGB (NCT01040533)
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of California, San Francisco
Severe Malnutrition
Integrated Program for Children With Severe Acute Malnutrition in Madhya Pradesh, India
The purpose of this study is to assesses the effectiveness of an integrated model for the management of severe acute malnutrition (IM-SAM) in India comprising facility- and community-based care and using locally-adapted protocols
- Trial name
- NCT01917734
- Testing
- Therapeutic feeding for children with SAM
- Where
- India
- Volunteers
- 2,740 people
- Sponsor
- Victor M. Aguayo
Severe Acute Malnutrition
The Effect of Routine Antibiotic Use in the Outpatient Treatment of Severely Malnourished Children Without Complications
This study will be conducted as a randomized, double-blind, placebo-controlled trial to compare routine antibiotic prescription vs.
- Trial name
- NCT01613547
- Testing
- Amoxicillin
- Where
- Niger
- Volunteers
- 2,412 people
- Sponsor
- Epicentre
Kwashiorkor
The Role of Sulfur Amino Acids in Risk of Kwashiorkor
This observational cross-sectional study is investigating if young children in populations with higher prevalence of kwashiorkor malnutrition have lower dietary sulfur amino acid intake than populations with lower prevalence of…
- Trial name
- NCT03520621
- Testing
- No intervention
- Where
- Democratic Republic of the Congo
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Tufts University