Clinical trials: Severe Acute Malnutrition
Severe Acute Malnutrition
Gastrointestinal Tolerance of Under-five Children With Severe Acute Malnutrition to ONS Compared to F-75/F-100
The primary outcome of the study is to identify gastrointestinal tolerance of under-five children with severe acute malnutrition to ready-to-drink high energy (1.5 kcal/ml) and standard energy (1 kcal/ml) oral nutrition…
- Trial name
- NCT04715204
- Testing
- High Energy Oral Nutrition Supplement, Standard Energy Oral Nutrition Supplement, Formula-75/Formula-100
- Where
- 2 sites in Indonesia
- Volunteers
- 108 people
- Sponsor
- Universitas Indonesia
Severe Acute Malnutrition, Cognitive Impairment
Choline to Improve Malnutrition and Enhance Cognition
The goal of this clinical trial is to test adding choline to ready-to-use therapeutic food (RUTF) in children with severe acute malnutrition (SAM) in Malawi.
- Conditions
- Severe Acute Malnutrition, Cognitive Impairment, Wasting, Kwashiorkor
- Trial name
- CHIME-SAM (NCT06154174)
- Testing
- C-RUTF (Ready-to-Use Therapeutic Food with added choline), S-RUTF (Ready-to-Use Therapeutic Food without added choline), Amoxicillin
- Where
- 10 sites in Malawi
- Volunteers
- 1,500 people
- Sponsor
- Washington University School of Medicine
Severe Acute Malnutrition
Pilot of a Prebiotic and Probiotic Trial in Young Infants With Severe Acute Malnutrition
Malnutrition is an ever-present problem worldwide. It is estimated that over 18 million children under the age of 5 are affected by the most extreme form of undernutrition, severe acute malnutrition (SAM).
- Trial name
- NCT03666572
- Testing
- Bifidobacterium infantis, Bifidobacterium infantis with prebiotic Lacto-N-neotetraose [LNnT]
- Where
- Bangladesh
- Volunteers
- 87 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Malnutrition; Protein, Frail Elderly Syndrome
Influence of Preoperative Nutritional Status on Perioperative Period in Cardiac Surgery in Patients With Frailty
The aim of the study is to determine whether the optimisation of the preoperative nutritional status affects the course of the perioperative period in patients with frailty.
- Trial name
- NCT05118165
- Testing
- Dietary supplement with protein
- Volunteers
- 176 people
- Sponsor
- Lithuanian University of Health Sciences
Malaria, Falciparum, Malnutrition
Efficacy of Artesunate-amodiaquine (AS-AQ) in Children With Malaria and Severe Acute Malnutrition, Madaoua, Niger 2010
The purpose of the study is to determine whether the artesunate-amodiaquine combination is effective in treating uncomplicated Plasmodium falciparum malaria in children with severe acute malnutrition.
- Conditions
- Malaria, Falciparum, Malnutrition, Child
- Trial name
- NCT01204411
- Testing
- Artesunate-amodiaquine fixed-dose combination
- Where
- Niger
- Sponsor
- Epicentre
Malaria, Severe Acute Malnutrition
Efficacy and Bio-availability of Artemether-Lumefantrine in Severely Malnourished Children
The general objective of the study is to answer to the question: "Is the current dose of AL less efficacious in the severely malnourished compared to the non-severely malnourished children, and is PK in cause?" We aim to assess…
- Trial name
- MAL-NUT (NCT01958905)
- Testing
- Artemether-lumefantrine fixed combination
- Where
- 2 sites in Mali, Niger
- Volunteers
- 399 people
- Sponsor
- Epicentre
Malnutrition, Child, Malnutrition, Infant
Mother Screening for Relapse Using Mid-upper Arm Circumference Among Children Recovered From Severe Acute Malnutrition (Full Scale Trial)
A 1:1:1 individually randomized unmasked controlled trial is proposed in which caregivers will be trained to screen their children who have recovered from an episode of SAM (severe acute malnutrition) using MUAC (mid-upper arm…
- Conditions
- Malnutrition, Child, Malnutrition, Infant, Malnutrition or Risk of Malnutrition, Hemoglobin Level Measurement
- Trial name
- MAMAN (NCT06599580)
- Testing
- Training caregivers to screen children for malnutrition relapse, Reduced follow-up schedule
- Where
- Burkina Faso
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Stunting, Malnutrition; Protein
Protein Plus: Improving Infant Growth Through Diet and Enteric Health
This cluster-randomized controlled trial is designed to address linear growth faltering in 6-12-mo-old Bangladesh infants through a proof-of-concept package of interventions to a) increase intake of high quality protein and b)…
- Conditions
- Stunting, Malnutrition; Protein, Enteric Pathogens, Campylobacter Infections
- Trial name
- JiVitA-6 (NCT03683667)
- Testing
- Azithromycin Oral Product, Protein Supplement, Isocaloric Supplement
- Where
- Bangladesh
- Volunteers
- 5,283 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Severe Malnutrition
Integrated Program for Children With Severe Acute Malnutrition in Madhya Pradesh, India
The purpose of this study is to assesses the effectiveness of an integrated model for the management of severe acute malnutrition (IM-SAM) in India comprising facility- and community-based care and using locally-adapted protocols
- Trial name
- NCT01917734
- Testing
- Therapeutic feeding for children with SAM
- Where
- India
- Volunteers
- 2,740 people
- Sponsor
- Victor M. Aguayo
Moderate Acute Malnutrition, Stunting
Eggs for Gut Health
The goal of this clinical trial is to test egg powder supplementation in children with moderate acute malnutrition in Sierra Leone.
- Conditions
- Moderate Acute Malnutrition, Stunting, Environmental Enteric Dysfunction, Severe Acute Malnutrition
- Trial name
- NCT06002438
- Testing
- Whole egg powder, Corn powder, Supercereal Plus
- Where
- 10 sites in Sierra Leone
- Volunteers
- 461 people
- Sponsor
- Washington University School of Medicine
Malnutrition; Protein
True Ileal Amino Acid Digestibility of Tenebrio Molitor Larvae in Women
Dietary protein intake of adequate quality is essential for human health. Traditional animal source foods play a key role in providing high quality protein but are associated with a high burden on the environment.
- Trial name
- NCT05885191
- Testing
- 2H intrinsically-labeled T.molitor with 13-C labeled amino acid mixture
- Where
- Switzerland
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Diego Moretti