Clinical trials: Severe Acute Pancreatitis
Severe Acute Pancreatitis
Effect of Electroacupuncture on SAP With MODS
1. Title: Effect of Electroacupuncture on Severe Acute Pancreatitis with Multiple Organ Disfunction Syndrome patients: A Randomized Clinical Trial 2. Research center: single center 3.
- Trial name
- NCT04813510
- Testing
- electroacupuncture treatment
- Volunteers
- 110 people
- Sponsor
- Jianbo Yu
Acute, Pancreatitis
Soluble Triggering Receptor Expressed on Myeloid Cells in Severe Acute Pancreatitis
Early diagnosis of secondary infection of necrotic tissue in severe acute pancreatitis is extremely important. The investigators evaluated whether the level of soluble TREM-1 (sTREM-1) in fine needle aspiration (FNA) fluid from…
- Trial name
- STREM-1 (NCT01193413)
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Changhai Hospital
Pancreatitis
The Development of Pancreatic Injury in the Course of Severe Acute Respiratory Syndrome Coronavirus 2 Infection
Although COVID-19 disease due to Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) affects the respiratory tract, heart and coagulation system, symptoms of gastrointestinal system involvement such as abdominal pain…
- Trial name
- NCT04433754
- Testing
- biochemical analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people
- Sponsor
- Uşak University
Postoperative Nausea
Entral Feeding in Acute Severe Pancreatitis
A total of 60 patients admitted to King Abdulaziz Specialists Hospital between June 2018 and April 2020 with both a clinical and biochemical presentation of acute pancreatitis with the following inclusion criteria: Abdominal pain…
- Trial name
- NCT04406506
- Testing
- nasogastric, nasojejunal, (erythromycin 250 mg IV bolus)
- Where
- Saudi Arabia
- Volunteers
- 60 people
- Sponsor
- King Abdul Aziz Specialist Hospital
Acute Pancreatitis
Activated Protein C in Severe Acute Pancreatitis
Activated protein C (APC)has been shown to reduce mortality in severe sepsis(Bernard et al. 2001b). The clinical picture of severe acute pancreatitis (AP) is similar to that of sepsis.
- Trial name
- NCT01017107
- Testing
- Activated protein C
- Where
- Finland
- Volunteers
- 32 people
- Sponsor
- Helsinki University Central Hospital
Pancreatitis,Acute Necrotizing
Multi-center Clinical Study of Early Antibios of Severe Acute Pancreatitis
Strategy of antibiotic therapy in SAP,De-escalate (cefoperazone+metronidazole) or Escalate (meropenem) therapy,which one is better.
- Trial name
- NCT01992198
- Testing
- cefoperazone + metronidazole, oral care by chlorhexidine gluconate, enteral nutrition
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Erzhen Chen
Acute Pancreatitis, Hypertriglyceridemia
Intensive Insulin for Severe/Moderate Hypertriglyceridemia Pancreatitis.
The aim of this study is to investigate the therapeutic efficacy of intensive insulin in patients with hypertriglyceridemia induced moderate/severe acute pancreatitis on the course and outcome of disease.
- Trial name
- HAPinsulin (NCT03501680)
- Testing
- Insulin, plasmapheresis
- Volunteers
- 200 people
- Sponsor
- First Affiliated Hospital of Wenzhou Medical University
Pancreatitis
Therapeutic Hypothermia for Severe Acute Pancreatitis
Background: Acute pancreatitis is characterized by a high mortality rate (10%-15%), and a remarkably unpredictable clinical course.
- Trial name
- NCT01794858
- Testing
- Therapeutic Hypothermia
- Where
- United States
- Sponsor
- NYU Langone Health
Post-ERCP Acute Pancreatitis
Prediction of PEP Based on the Appearance of the Major Duodenal Papilla
This observational, prospective study aims at evaluating how the occurrence of post-Endoscopic Retrograde CholangioPancreatography (ERCP) acute pancreatitis (PEP) could be influenced by difficult biliary cannulation that might be…
- Trial name
- PredERCP (NCT05800626)
- Testing
- Endoscopic Retrograde Cholangio-Pancreatography (ERCP)
- Where
- 2 sites in Italy
- Volunteers
- 1,740 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Pancreatitis, Acute Necrotizing
Effect of Traditional Chinese Medicine on GI Function Recovery and Nutrition Support in SAP
With multicenter randomized control clinical evaluation investigations, the effect of traditional Chinese medicine on gastrointestinal function recovery and nutrition support in early stage of severe acute pancreatitis (SAP) was…
- Trial name
- NCT00508729
- Testing
- Qingyi granules
- Where
- 10 sites in China
- Volunteers
- 300 people
- Sponsor
- Tianjin Nankai Hospital
Severe Acute Pancreatitis Patients
Early Rehabilitation for Severe Acute Pancreatitis (ERN-SAP)
This prospective, randomized controlled trial investigates the efficacy of a structured early rehabilitation nursing (ERN) program compared to usual care in patients with severe acute pancreatitis (SAP).
- Trial name
- NCT07109921
- Testing
- Structured Early Rehabilitation Nursing Program, Usual Care
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Sixth Hospital of Wuhan, Affiliated Hospital of Jianghan University
Severe Acute Pancreatitis, Intra-abdominal Hypertension
Efficacy and Safety of Da-Cheng-Qi Decoction in Severe Acute Pancreatitis
This single-center prospective randomized controlled trial evaluated Da-Cheng-Qi Decoction (DCQD) as the acute-stage intervention of an integrated traditional Chinese and Western medicine whole-stage treatment protocol for severe…
- Trial name
- NCT07816900
- Testing
- Da-Cheng-Qi Decoction Plus Standard Western Treatment, Standard Western Treatment
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Severe Acute Pancreatitis
A Trial of Early Percutaneous Catheter Drainage of Sterile Pancreatic Fluid Collections in Severe Acute Pancreatitis
The acute peripancreatic fluid collections (AFPCs) is the most common complication in severe acute pancreatitis (SAP). There are controversies on optimal timing for drainage of APFCs in SAP.
- Trial name
- EPCDSAP (NCT03185806)
- Testing
- Puncture and drainage
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Pancreatitis
Fluid Resuscitation Goal in Early Stage of Severe Acute Pancreatitis
To compare different goals of fluid resuscitation in early stage of acute pancreatitis
- Trial name
- NCT01974466
- Testing
- Goal A, Goal B
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Ruijin Hospital
Acute Pancreatitis (AP), Severe Acute Pancreatitis
Bowel Sound in Predicting the Severity of Acute Pancreatitis: Protocol of a Prospective, Multi-center Study
Introduction: Acute pancreatitis (AP) is a common condition, with 20% of cases progressing to severe acute pancreatitis (SAP), which is associated with a poor prognosis.
- Trial name
- NCT06867120
- Where
- China
- Volunteers
- 352 people
- Sponsor
- Peking Union Medical College Hospital
Acute Pancreatitis (AP), Diabetes Mellitus
Endocrine and Exocrine Secretory Function Alterations After Moderately Severe and Severe Acute Pancreatitis
The goal of this observational study is to learn about post-acute pancreatitis diabetes mellitus (PPDM-A). The main questions it aims to answer are: 1.
- Trial name
- NCT06590935
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Shanghai Changzheng Hospital
Acute Respiratory Distress Syndrome (ARDS)
Metoprolol in Acute Respiratory Distress Syndrome (MAIDEN)
Randomised, double-blind, placebo-controlled clinical trial to evaluate the efficacy of intravenous metoprolol in patients with Acute Respiratory Respiratory Distress Syndrome (ARDS).
- Trial name
- MAIDEN (NCT05847517)
- Testing
- Metoprolol Injection, saline 0.9%
- Where
- 12 sites in Spain
- Volunteers
- 14 people
- Sponsor
- Consorcio Centro de Investigación Biomédica en Red (CIBER)
Severe Acute Pancreatitis, Pancreatic Necrosis
Percutaneous Continuous Irrigation Combined With Transgastric Necrosectomy usingLAMS in Treatment of SAP
Severe acute pancreatitis (SAP) is the most severe form of acute pancreatitis (AP) and Infection of pancreatic necrosis (IPN) have shown to be one of the decisive factors defining the severity of illness.
- Trial name
- PCISLAMS (NCT05508828)
- Testing
- Percutaneous Continuous Irrigation assisted Vacuum Drainage Combined With Transgastric Necrosectomy
- Where
- China
- Volunteers
- 8 people
- Sponsor
- Chinese Medical Association
Acute Pancreatitis
Early Goal-directed Volume Resuscitation in Severe Acute Pancreatitis
Acute pancreatitis (AP) is a common disorder with rising incidence varying between 35 and 80 per 100,000 in Europe and the USA. About 15% of patients develop necrotizing pancreatitis (NP) with a mortality of up to 42% and…
- Trial name
- EAGLE (NCT00894907)
- Testing
- PiCCO-parameter-guided volume resuscitation, Control-group
- Where
- Germany
- Volunteers
- 190 people
- Sponsor
- Technical University of Munich
Acute Pancreatitis
Study of New Biological Markers for Prediction of Severe Acute Pancreatitis
Acute pancreatitis refers to inflammation of the pancreas and is associated with sudden onset of severe abdominal pain, often accompanied by transient systemic manifestations, including fever.
- Trial name
- NCT00786591
- Where
- Singapore
- Volunteers
- 75 people
- Sponsor
- National University Hospital, Singapore