Clinical trials: Severe Burn Injury
Burn Wound
Clinical Efficacy and Safety of Autologous Cultured Keratinocyte Cell on Severe Burn Wood
The efficacy and safety of Autologous cultured keratinocyte cell on severe burn wound.
- Trial name
- keratinocyte (NCT00978705)
- Testing
- Autologous cultured keratinocyte cell
- Where
- South Korea
- Volunteers
- 19 people
- Sponsor
- Biosolution Co., Ltd.
Burns
Assessment of the Treatment of Severely Burned With Anabolic Agents on Clinical Outcomes, Recovery and Rehabilitation
The purpose of the program is to study and characterize the outcome of burn injury with particular attention to improving the rehabilitation of burn survivors, including children.
- Trial name
- NCT00675714
- Testing
- Stable Isotope Infusion Study, Collection of blood and tissues, Radiology testing: Dual-energy X-ray absorptiometry (DEXA), ultrasound, MRI
- Where
- United States
- Volunteers
- 1,126 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Burns, Burn Injury
Predictive Role of Glucose/Potassium Ratio on Mortality in Major Burns.
The aim of this observational study is to investigate the role of the glucose-potassium ratio in predicting mortality in patients with major burn trauma.
- Conditions
- Burns, Burn Injury, Inhalation Injury
- Trial name
- NCT06561282
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Konya Meram State Hospital
Burns
The Effects of Viscoelastometry Guided Resuscitation During Burn Excision on Post Resuscitation Infections
This is a randomized controlled trial to compare viscoelastometric (VE) guided transfusion to standard practice transfusion in severe thermal injury burn excision on the utilization of blood products, effects on coagulation and…
- Trial name
- NCT03730415
- Testing
- Viscoelastic (VE) Guided Transfusion
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Texas Southwestern Medical Center
Burns
Efficacy and Safety for Different Regimen of VTE Pharmacoprophylaxis Among Severely Burn Patients
This study aims to assess the feasibility and safety of VTE prophylaxis for 3 modality regimens (Unfractionated heparin 5000 U SQ q8 hours, Enoxaparin 40 mg SQ q24 hours or Enoxaparin 30 mg SQ q12 hours) in adult patients (≥18…
- Trial name
- NCT05237726
- Testing
- Enoxaparin 40 mg q24 hours, Enoxaparin 30 mg q12 hours, Unfractionated heparin 5000 U q8 hours
- Where
- Saudi Arabia
- Volunteers
- 20 people
- Sponsor
- King Abdullah International Medical Research Center
Severe Burn, Enternal Nutrition
A Study on Nutrition Support in Adult Patients With Severe Burns
To delineate nutritional support in adults patients with severe burns to investigate associations between nutritional practice and clinical outcomes.
- Trial name
- NCT03379116
- Testing
- enteral nutrition and parenteral nutrition
- Volunteers
- 100 people
- Sponsor
- Southeast University, China
Burns, Coagulation Disorder
Factor XIII in Major Burns Coagulation
Prospective observational study in which FXIII levels and coagulation tests and cicatrization are measured during the 30 days after the thermal trauma.
- Conditions
- Burns, Coagulation Disorder, Factor XIII Deficiency, Cicatrization
- Trial name
- NCT03188913
- Testing
- Coagulation tests
- Volunteers
- 20 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Burns
Effect of rFVIIa on Peri-operative Blood Loss in Patients Undergoing Major Burn
The purpose of the study is to see if a medication (Recombinant Coagulation Factor VIIa or NovoSeven), normally used to stop bleeding in persons with a bleeding disorder, will lower the amount of blood lost during burn surgery.
- Trial name
- NCT00243243
- Testing
- Recombinant Factor VIIa
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- United States Army Institute of Surgical Research
Severe Burn
Albumin and Prognosis of Severely Patients Burns
Hemodynamic management has long been identified as a key factor affecting burn prognosis. However, large amounts of crystalloid infusion have been associated with the development or aggravation of organ failure (acute respiratory…
- Trial name
- ALBUBURN (NCT04264065)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pain, Cancer
Extension Study of ACTIQ Treatment for Children and Adolescents With Breakthrough Pain
The objective of the study is to monitor the safety (adverse event data) of longer-term use of ACTIQ (Oral Transmucosal Fentanyl Citrate [OTFC]) treatment in children with pain associated with cancer, sickle cell disease, or…
- Conditions
- Pain, Cancer, Sickle Cell Anemia, Severe Burns
- Trial name
- NCT00236093
- Testing
- ACTIQ (Oral Transmucosal Fentanyl Citrate [OTFC])
- Where
- 28 sites in United States, Canada and 1 more
- Sponsor
- Cephalon
Chronic Pain Following Thermal Burn Injury
Vitamin D and n-3 Polyunsaturated Fatty Acids (PUFAs) to Prevent Chronic Pain Following Major Thermal Burn Injury
The goal of this study is to develop a safe, effective, and readily available treatment that will prevent chronic pain following Major Thermal Burn Injury (MThBI).
- Trial name
- NCT03313076
- Testing
- Omega-3 fatty acids (fish oil), Vitamin D3 (cholecalciferol)
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of North Carolina, Chapel Hill
Burns, Trauma
Microcirculatory Assessment in Patients With Trauma and Severe Burns
Predict the development of multiple organ failure in patients with trauma and severe burns.
- Trial name
- NCT01922960
- Testing
- micro-imaging
- Where
- United States
- Sponsor
- University of South Alabama
Burn Injury, Psychosocial Problem
Effects of a Community Based Exercise Program in Adults With Severe Burns
The purpose of this proposal is to assess the efficacy of implementing a 12-week structured and supervised community-based exercise program (COMBEX) at hospital discharge.
- Conditions
- Burn Injury, Psychosocial Problem, Quality of Life
- Trial name
- COMBEX (NCT01184547)
- Testing
- Combex, Standard of Care
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Antibiotics, Severe Burn
Determining Drug Levels of Beta-lactam Antibiotics in Severe Burned Patients
At antibiotic stewardship of the University Hospital of Schleswig-Holsten it was noticed that there are much less studies measuring drug levels in severe burned patients than are required.
- Conditions
- Antibiotics, Severe Burn, Intensive Care
- Trial name
- MSBV (NCT03335137)
- Testing
- Drug Level Monitoring
- Where
- Germany
- Volunteers
- 35 people
- Sponsor
- University Hospital Schleswig-Holstein
Burns, Physiotherapy
The Effect of Early Physiotherapy on Biochemical Parameters in Major Burn Patients: A Burn Center's Experience
Background: This study planned to investigate the effect of early physiotherapy on biochemical parameters in major burn patients. Methods: Ten women (50%) and 10 men (50%) aged 21-47 years old were included in our study.
- Conditions
- Burns, Physiotherapy, Exercises
- Trial name
- NCT03520816
- Testing
- Burn Physiotherapy Protocol
- Volunteers
- 20 people
- Sponsor
- Hasan Kalyoncu University
Burns
Cardiovascular Biomarkers and Lung Edema in Severe Burns Patients
Burn injury leads to hypovolemic then distributive shock. Fluid resuscitation remains the cornerstone of initial treatment of burn shock.
- Trial name
- CAROLE (NCT03271268)
- Where
- France
- Volunteers
- 36 people
- Sponsor
- Saint-Louis Hospital, Paris, France
Burn Scar
Microneedling for Burn Hypertrophic Scars
Approximately 33 to 91% of severe burn victims will develop hypertrophic scars. Hypertrophic scars are defined as erythematous (red), raised and rigid scars that can cause pain and itching, among other things.
- Trial name
- NCT05423613
- Testing
- Microneedling
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Analgesia, Burns
Analgesic Effect of Esketamine in DCSB in Adultscontrolled Study
Patients with severe and above degree burns are often complicated with inhalation injury and systemic infection. During debridement and dressing change in such patients, doctors will be more cautious in using analgesics.
- Trial name
- NCT05603975
- Testing
- Esketamine 0.1mg/kg intravenous injection, Normal saline
- Volunteers
- 52 people
- Sponsor
- Shenzhen Second People's Hospital
Burn
High-Dose Vitamin D Deficiency in Burn Injury
High dose Vitamin D (50,000IU) therapy may increase bone mineral density/bone mineral content after large burns.
- Trial name
- VitaminD (NCT00591604)
- Testing
- Vitamin D
- Sponsor
- The University of Texas Medical Branch, Galveston
Severe Burn Injury
Balanced Volume Replacement Therapy With Ringer's Acetate Solution in Burn Injury
This observational study compares the influence of Ringer's Lactate solution and Ringer's Acetate solution on organ function scores following severe burn injury.
- Trial name
- VoLTRAB (NCT00609700)
- Where
- Germany
- Volunteers
- 82 people
- Sponsor
- Klinikum St. Georg gGmbH