Clinical trials: Severe Early Childhood Caries
Early Childhood Caries
Study of Obstacles and Barriers to Changing Risky Eating Behaviors in Families of Children With Severe Early Childhood Caries (QUALIKIDS).
Dental caries is the most common chronic disease in children, and its early form-Early Childhood Caries (ECC)-which particularly affects children under the age of six, represents a major public health problem worldwide.
- Trial name
- QUALIKIDS (NCT07377240)
- Testing
- Interview
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Severe Early Childhood Caries, Dental Caries
Salivary Antimicrobial Peptides and Severe Early Childhood Caries in Turkish Children
This observational study aims to evaluate the relationship between salivary antimicrobial peptides and severe early childhood caries (S-ECC) in Turkish children.
- Trial name
- NCT07414030
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Severe Early Childhood Caries
Thiol/Disulfide and Oxidative Stress
The aim of this study was to evaluate the role of thiol/disulfide homeostasis and oxidative stress in the saliva of children with severe early childhood caries
- Trial name
- NCT04655859
- Testing
- saliva cotton swab
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Early Childhood Caries
A Clinical Trial of Silver Diamine Fluoride to Arrest Early Childhood Caries in Young Children
Silver diamine fluoride (SDF) is an antibiotic liquid that has the potential to arrest Early Childhood Caries in young children and delay treatment until children can be seen in outpatient settings.
- Trial name
- NCT04054635
- Testing
- Silver diamine fluoride
- Where
- Canada
- Volunteers
- 84 people
- Sponsor
- University of Manitoba
Early Childhood Caries
A Telephone-based Case-management Intervention for Caries Prevention in Children With Severe Early Childhood Caries
Despite improvements in oral health among children, children living in areas characterized by low socio-economic status still have a significant disease burden with regard to dental caries.
- Trial name
- NCT02487043
- Testing
- A telephone-based case-management intervention
- Where
- Sweden
- Volunteers
- 151 people
- Sponsor
- Karolinska Institutet
Severe Early Childhood Caries, Caries
Construction of a Multidimensional Risk Prediction Model for Severe Early Childhood Caries
This study aims to address the high prevalence and recurrence rate of severe early childhood caries (S-ECC) by breaking away from the traditional single biological factor perspective and introducing the theories of "24-hour…
- Trial name
- NCT07335744
- Testing
- questionnaire survey
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- The Children's Hospital of Zhejiang University School of Medicine
Candida Infection, Oral Thrush
Oropharyngeal Candidiasis (OPC) and S-ECC
The overall objective of this study is to investigate the association of early Candida infection (known as oral thrush or oropharyngeal candidiasis, OPC) in children during the first year of life with the onset and severity of…
- Conditions
- Candida Infection, Oral Thrush, Early Childhood Caries
- Trial name
- Oral-Thrush (NCT05761197)
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Temple University
Early Childhood Caries (ECC)
Zirconia Crowns Versus Extraction of Primary Anterior Teeth
Severely mutilated anterior primary teeth in preschool children are frequently managed by extraction. However, premature loss of anterior primary teeth has been associated with adverse functional, developmental and psychosocial…
- Trial name
- NCT07719478
- Testing
- Zirconia Crown, Extraction
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Passant Nagy
Dental Caries in Children
Salivary Antioxidant Capacity Before and After Complete Dental Rehabilitation
Salivary samples were obtained from 20 children in their fifth year of life diagnosed S-ECC and 20 age and sex matched controls.
- Trial name
- NCT03432728
- Testing
- Dental rehabilitation under general anesthesia
- Where
- Saudi Arabia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Riyadh Colleges of Dentistry and Pharmacy