Clinical trials: Severe Obesity
Weight Loss, Metabolism and Nutrition Disorder
The Effect of High vs. Moderate Protein Consumption on Human Health
The study will be conducted as a parallel randomized controlled intervention trial, initiated by eight weeks rapid weight loss with one of two VLCDs, one week of reintroducing regular foods, and 12 weeks with one of two different…
- Conditions
- Weight Loss, Metabolism and Nutrition Disorder, Obesity
- Trial name
- BEEF (NCT04156165)
- Testing
- VLCD-Active, Maintenance-Active, VLCD-Control
- Where
- Denmark
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Morbid Obesity
Study to Determine Effective Dosing of Fondaparinux in Obese Persons
This is a prospective open-label study comparing two dosing regimens of fondaparinux, which is used to prevent deep vein thrombosis, in morbidly obese volunteers.
- Trial name
- NCT00346879
- Testing
- fondaparinux
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Indiana University
Obesity & Overweight, Sleeve Gastrectomy
Istmin Levels in Laparoscopik Sleeve Gastrectomy
Obesity is a multifactorial disease which has become a public health problem with increasing frequency, especially in recent years.
- Conditions
- Obesity & Overweight, Sleeve Gastrectomy, Adipokines
- Trial name
- NCT07335549
- Testing
- Preoperative Serum Isthmin Levels, Postoperative Third Month's Serum Isthmin Levels, Preoperative BMI
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Obesity
Exercise Training and Fitness in Severe Obesity
Obesity is commonly associated with insulin resistance and hyperinsulinemia, which seem to be linked with an impaired ability to oxidize lipids, particularly in class III obese individuals [Body Mass Index (BMI): > 40 kg*m-2].
- Trial name
- INTFMOBE (NCT02254200)
- Testing
- Fatmax group, HIIT group
- Where
- Italy
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Istituto Auxologico Italiano
Severe Mental Disorder, Obesity
Health Education Programme Through Physical Exercise for People With Severe Mental Disorders
The goal of this clinical trial is to [learn about, test, compare etc.] in individuals with severe mental disorders and obesity comorbid.
- Trial name
- HEPPE-PSMI (NCT06069739)
- Testing
- Guided physical activity, Standard physical activity
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Fundación para la Investigación del Hospital Clínico de Valencia
Morbid Obesity, Overweight
Pharmacokinetics in Morbid Obesity After Bariatric Surgery
Morbid obesity (MO) is associated with several disorders such as hypertension, type 2 diabetes, dyslipemia and degenerative arthropathy that require pharmacological treatment.
- Trial name
- FAROBE/1 (NCT01086722)
- Testing
- "karolinska cocktail"
- Where
- 2 sites in Spain
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Fundacion IMIM
Morbid Obesity
Effect of Gastric Balloon in Morbid Obesity: Prospective Study
The aim of this study is to compare the efficacy of gastric balloon in weight reduction among two different categories of morbidly obese people.
- Trial name
- NCT02128165
- Testing
- BMI more than 45 BMI, BMI less than 45 BMI
- Where
- Egypt
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Obesity, Extreme Obesity
Identification and Characterization of Youth With Extreme Obesity
While obese and extremely obese youth are at increased risk of health complications, especially the extremely obese group rarely seek medical care. One of the underlying reasons might be the lack of adequate treatment options.
- Trial name
- YES (NCT01625325)
- Where
- 5 sites in Germany
- Volunteers
- 429 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Martin Wabitsch
Fetus Fetus, Pregnancy Complications
the Fetal Epicardial Thickness in Obese Pregnant Women (EFT)
the effects of fetal EFT on fetal cardiac function and fetal and maternal outcomes were investigated in obese pregnant women compared with normal-weight pregnant women.
- Trial name
- EFT (NCT05948319)
- Testing
- Doppler ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Obesity, Morbid, Time Restricted Eating
Time-restricted Eating Among Pregnant Females With Severe Obesity
In the United States, a body mass index (BMI) of at least 35.0 kg/m2 affects about 15% of women of reproductive age. Severe obesity is a significant predictor of adverse perinatal outcomes including gestational diabetes mellitus…
- Conditions
- Obesity, Morbid, Time Restricted Eating, Pregnancy Weight Gain
- Trial name
- TRE-Preg (NCT06477120)
- Testing
- Time Restricted Eating
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Morbid Obesity
Longitudinal Assessment of Bariatric Surgery
The goal of the LABS-1 study is to assess the short-term safety of bariatric surgery.
- Trial name
- LABS-1 (NCT00433810)
- Where
- 10 sites in United States
- Volunteers
- 5,102 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh