Clinical trials: Severe Obesity
Clinically Severe Obesity, Gastroesophageal Reflux Disease
Gastric Bypass After Previous Anti-reflux Surgery
The goal of this study is to describe the clinical presentation, indications, and operative treatment as well as assess the morbidity, mortality, and overall performance of revisional Roux-en-Y gastric bypass (RYGB) after either…
- Trial name
- RYGBafterARS (NCT01041105)
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of California, San Francisco
Morbid Obesity
Endoscopic Gastric Tubulization
Endoscopic gastric tubulization is currently proposed in the Digestive Surgery Department of the Nouvel Hôpital Civil, Strasbourg, France, to adult patients with morbid obesity.
- Trial name
- Endosleeve (NCT03554902)
- Testing
- Endoscopic gastric tubulization
- Where
- France
- Volunteers
- 300 people
- Sponsor
- IHU Strasbourg
Severe Obesity, Sleeve Gastrectomy
Longitudinal Retrospective Analysis of Prospectively Collected Data for Outcomes After Primary Sleeve Gastrectomy (N=20 000) in the Swedish National Quality Registry SOReg (Scandinavian Obesity Surgery Registry)
The main questions to answer are: Weight outcomes in weight strata over time? What was the proportion of patients reaching sufficient weight outcome in different weight strata? To what extent are co-morbid conditions improved or…
- Trial name
- SCAN (NCT07280845)
- Where
- Sweden
- Volunteers
- 19,977 people
- Sponsor
- Linkoeping University
Morbid Obesity
Lifestyleintervention for the Treatment of Severe Obesity
The overall purpose of this project is to study the acute, short- (≤ 1 year) and long- (> 1 year) term effects on body composition and psychological health after a 10 to 14-weeks comprehensive lifestyle modification program for…
- Trial name
- NCT01675713
- Testing
- Intensive lifestyle intervention
- Where
- Norway
- Volunteers
- 149 people
- Sponsor
- Norwegian School of Sport Sciences
Sleeve Gastrectomy With Jejunoileal Anastomosis
Evaluation of Patients Who Underwent Sleeve Gastrectomy With Jejunoileal Anastomosis for the Treatment of Morbid Obesity
Laparoscopic sleeve gastrectomy operations performed for morbid obesity are among the most common methods in the world. Gastric or intestinal bypass surgery with or without sleeve gastrectomy is thought to be more effective in…
- Trial name
- NCT03939442
- Testing
- Sleeve gastrectomy with jejunoileal anastomosis
- Where
- Turkey (Türkiye)
- Volunteers
- 2 people
- Sponsor
- Inonu University
Liver Transplantation, Obesity
Sleeve Gastrectomy for Morbid-Obesity Sequelae After Transplantation
Complications associated with excess weight (hypertension, coronary artery disease and diabetes) have become major causes of morbidity and mortality after liver transplantation (LT).
- Trial name
- SG-4MOST (NCT03617744)
- Testing
- Sleeve gastrectomy
- Volunteers
- 50 people
- Sponsor
- University Health Network, Toronto
Obesity, Morbid, Type 2 Diabetes Mellitus
The Effects of the Laparoscopic Roux-en-Y Gastric Bypass and Laparoscopic Mini Gastric Bypass on the Remission of Type II Diabetes Mellitus
It is estimated that there will be 439-552 million people with type 2 diabetes mellitus (T2DM) globally in 2030. Type 2 Diabetes Mellitus is present in one quarter of patients at the bariatric outpatient clinic.
- Trial name
- DIABAR (NCT03330756)
- Testing
- laparoscopic Roux-en-Y gastric bypass, laparoscopic Mini gastric bypass
- Where
- Netherlands
- Volunteers
- 220 people
- Sponsor
- Slotervaart Hospital
Pulmonary Atelectasis, Respiratory Tract Diseases
Use of Positive Pressure in Morbidly Obese Patients Undergoing Reduction Stomach Surgery
The aim of this study was to investigate the effects of using positive pressure in the preoperative, intraoperative and postoperative morbidly obese individuals undergoing gastroplasty.
- Conditions
- Pulmonary Atelectasis, Respiratory Tract Diseases, Pathological Conditions, Signs and Symptoms
- Trial name
- NCT01786681
- Testing
- Positive pressure
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidade Metodista de Piracicaba
Obesity, Cardiac Function
Severe Obesity: Bariatric Surgery vs. Life-Style-Intervention
The purpose of this study is to investigate the effects of weight loss induced by gastric bypass surgery in comparison to a psychotherapy-enhanced lifestyle intervention on cardiopulmonary performance and quality of life in…
- Conditions
- Obesity, Cardiac Function, Quality of Life
- Trial name
- WAS (NCT01352403)
- Testing
- Roux-en-Y gastric bypass, Psychotherapy-enhanced lifestyle intervention
- Where
- Germany
- Volunteers
- 93 people
- Sponsor
- University of Wuerzburg
Morbid Obesity
Respiratory Quotient in Post Roux-en-Y Gastric Bypass Patients
Through the values of respiratory quotient (RQ) it is possible to estimate the utilization of energy substrates by the body, or if there is a higher or lower fat oxidation.
- Trial name
- RQ (NCT01396460)
- Testing
- breakfast (a chicken sandwich with juice)
- Where
- Brazil
- Volunteers
- 69 people
- Sponsor
- Gastrocirurgia, Brazil
Morbid Obesity, Obesity
Resistance Training in Patients With Morbid Obesity
The researchers will conduct a study for avoiding the metabolic syndrome in morbid obese patients. Thus, the aim of the present will be determine the effects of a resistance training programme (RT) in preventing or attenuating…
- Conditions
- Morbid Obesity, Obesity, Physical Activity, Metabolic Syndrome
- Trial name
- ExinMO (NCT03921853)
- Testing
- Behavioral
- Where
- Chile
- Volunteers
- 39 people
- Sponsor
- Universidad de Los Lagos
Obesity, Morbid, Surgery
Sleeve Versus Bypass in Older Patients: a Randomized Controlled Trial
The aim of the study is to compare two different bariatric procedures performed in patients with 65 years or more: gastric bypass and sleeve gastrectomy.
- Conditions
- Obesity, Morbid, Surgery, Elderly
- Trial name
- BaSE (NCT03339791)
- Testing
- Sleeve Gastrectomy, Gastric Bypass
- Where
- Brazil
- Volunteers
- 36 people
- Sponsor
- University of Sao Paulo General Hospital
Morbid Obesity
Sleeve Gastrectomy Versus Gastric Bypass for Private Pay Patients Seeking Obesity Surgery
The purpose of this study is to determine laparoscopic sleeve gastrectomy is a safer surgery than the gastric bypass, gives similar weight losses and that the safety of gastric in private pay patients versus insurance patients…
- Trial name
- NCT01063959
- Testing
- Laparoscopic Sleeve Gastrectomy, Laparoscopic Gastric Bypass
- Where
- United States
- Sponsor
- Pennington Biomedical Research Center
Morbid Obesity
Long-term Adverse Effects After Bariatric Surgery on Bone Density
The goal of this trial is to examine long-term effects of laparoscopic gastric bypass (LRYGB) and sleeve gastrectomy (LSG) on bone mineral density, fracture risk, and body composition ≥ 5 years post-surgery.
- Trial name
- FUB-A (NCT03410459)
- Testing
- DEXA (= Dual-energy x-ray absorptiometry)
- Where
- Switzerland
- Volunteers
- 140 people
- Sponsor
- University Hospital, Basel, Switzerland
Obesity
Re-energize With Nutrition, Exercise and Weight Loss
The purpose of this project is to establish a Center of Excellence in Research on Obesity that will focus on severe obesity. The prevalence of severe obesity (i.e., Class 2 and 3 obesity; body mass index > 35 kg/m2 and 40 kg/m2)…
- Trial name
- RENEW (NCT00712127)
- Testing
- Diet and Exercise, Diet and Exercise-Delayed
- Where
- 2 sites in United States
- Volunteers
- 310 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Morbid Obesity, Liver Fat
Low-calorie Diet and Body Composition Prior to Roux-en-Y Gastric Bypass
Losing weight before undergoing Roux-en-Y gastric bypass (RYGB) surgery may reduce liver fat content and size thereby improving surgical outcomes.
- Trial name
- LCD (NCT02144597)
- Testing
- Liquid formula low-calorie diet (LCD), Roux-en-Y gastric bypass (RYGB), Control diet
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Imperial College London
Obstructive Sleep Apnea
Effect of a Very Low Calorie and Low Calorie Diet on Moderate to Severe Obstructive Sleep Apnea in Obese Adults
The purpose of this study is to test the effectiveness of two different weight loss diets on obstructive sleep apnea (OSA) severity.
- Trial name
- NCT02251574
- Testing
- Low Calorie Diet, Very Low Calorie Diet, Standard Care
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Morbid Obesity, Surgery
Ketamine Infusion vs Dexmedetomidine Infusion in Obese Patients Undergoing Bariatric Surgery
The surgeries that involve treatment of morbid obesity, i.e. bypass procedure and sleeve gastrectomy, are collectively covered under the term 'bariatric surgery'.
- Trial name
- NCT04576975
- Testing
- Ketamine, Dexmedetomidine, Normal Saline 0.9%
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Morbid Obesity, Hyperglycemia
Characteristics of Dendritic Cells Before and After Gastric Banding
A research study to find out more about a specific white blood cell called a dendritic cell. These cells are found in a layer of fat in the body called the omentum.
- Conditions
- Morbid Obesity, Hyperglycemia, Diabetes Mellitus
- Trial name
- NCT00488930
- Testing
- Observational
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of California, San Diego
Obesity, Morbid Obesity
Monitoring Obese Patients : Impact on the Frequency of Monitoring Weight
The literature data show that long-term monitoring has an effect on weight loss, comorbidity and on improving the quality of life.
- Conditions
- Obesity, Morbid Obesity, Quality of Life
- Trial name
- SUIVIOBESITE (NCT02374866)
- Testing
- closer monitoring
- Where
- France
- Volunteers
- 96 people
- Sponsor
- University Hospital, Limoges