Clinical trials: Severe Obesity
COVID-19 Pandemic, Obesity
Obesity: an Underappreciate Risk Factor for Severe Form of COVID-19
Our study has the objective of identifying the epidemiological profil of the patients, as well as, the clinical, radiological and prognosis of obese patients with covid 19.
- Trial name
- NCT05771857
- Testing
- Obesity
- Where
- Morocco
- Volunteers
- 415 people, healthy volunteers welcome
- Sponsor
- Mohammed VI University Hospital
Depression, Major Depressive Disorder
Diet and Depression
This study is a pilot open label crossover trial to assess the feasibility and acceptability of reducing ultra- processed foods (UPF) in a personalized manner from the diets of patients with major depressive disorder who eat a…
- Conditions
- Depression, Major Depressive Disorder, Weight Gain, Obesity
- Trial name
- NCT06252701
- Testing
- Reduction of Ultra-processed foods
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, San Francisco
Morbid Obesity, Hyperglycemia
Characteristics of Dendritic Cells Before and After Gastric Banding
A research study to find out more about a specific white blood cell called a dendritic cell. These cells are found in a layer of fat in the body called the omentum.
- Conditions
- Morbid Obesity, Hyperglycemia, Diabetes Mellitus
- Trial name
- NCT00488930
- Testing
- Observational
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of California, San Diego
Morbid Obesity, Satiety
Functional MRI Evaluation of Brain Response to Visual Food Stimulation in Morbidly Obese Patients Before and After Bariatric Surgery
Aim of study: To evaluate changes in feeding-related neural activity after different bariatric procedures in morbidly obese patients. Relationship of gut hormone levels will be assessed as well.
- Trial name
- NCT01140711
- Testing
- fMRI imaging following visual stimulation of food and non-food images
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Sheba Medical Center
Morbid Obesity Requiring Bariatric Surgery, Neck Pain Musculoskeletal
Changes in Cervical Posture, Cervical Function, and Neck Pain After Sleeve Gastrectomy
Obesity may contribute to neck pain, altered cervical posture, and impaired cervical function through increased mechanical loading, changes in body alignment, and reduced muscle performance.
- Trial name
- NCT07813429
- Testing
- Laparoscopic Sleeve Gastrectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people
- Sponsor
- Haydarpasa Numune Training and Research Hospital
Morbid Obesity
Outcomes of Gastric Band Fills as Found With a Patient Self-reported Questionnaire: The Vomiting, Eating, and Weight Loss (VEW) Questionnaire
1. Background / Scientific Rationale The VEW (Vomiting, Eating, and Weight Loss) Questionnaire has been developed as a method for the assessment of post bariatric surgery patients, as well as a research tool into the eating…
- Trial name
- NCT01105156
- Testing
- VEW Questionnaire
- Where
- Australia
- Volunteers
- 361 people
- Sponsor
- North Eastern Weight Loss Surgery
Morbid Obesity, Bariatric Surgery Candidate
Preoperative Condition in Giant Obese Patients
The frequency of super-super obese who need immediate weight loss surgery is risen continuously. For those patients a prior-to-surgery conditioning therapy is mandatory to gain technical and physical operability.
- Trial name
- NCT02616003
- Testing
- Liraglutide, Aminosteril hepa 8%, Caloric diet with 1000 kcal
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Sana Klinikum Offenbach
Diabetes Mellitus, Type 2, Obesity
Association of Diabetes and Metabolic Syndrome With Severe Malaria in Cameroon
The aim of this study is to investigate if diabetes, obesity and metabolic syndrome affects disease presentation and severity of malaria in adults in a hospital setting in Cameroon.
- Conditions
- Diabetes Mellitus, Type 2, Obesity, Metabolic Syndrome, Severe Malaria
- Trial name
- NCT05685875
- Testing
- diabetes
- Where
- 2 sites in Cameroon
- Volunteers
- 300 people
- Sponsor
- Karolinska Institutet
Morbid Obesity
Neurohumoral Control of Intestinal Electrical and Mechanical Activity
A collaborative research project with Dr. Kathleen Keef (Department of Physiology, University of Nevada School of Medicine, Reno, Nevada) studying the role of putative neurotransmitters in human intestine.
- Trial name
- NCT00852553
- Where
- 2 sites in United States
- Volunteers
- 45 people
- Sponsor
- University of California, Davis
Glucagon Like Peptide-1 (GLP-1, Delayed Gastric Emptying
GLP_1 RA Ultrasound Study
The purpose of the study is to determine whether patients taking GLP-1 RAs have increased residual (left behind), gastric (stomach), contents due to delayed gastric emptying when following standard preoperative fasting guidelines.
- Conditions
- Glucagon Like Peptide-1 (GLP-1, Delayed Gastric Emptying, Risk of Aspiration, Diabetes
- Trial name
- NCT06581120
- Testing
- Glucagon-Like Peptide-1 receptor agonists, Point of Care Gastric Ultrasound
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Morbid Obesity, Cesarean Delivery Affecting Fetus
Effect of CPAP on Fetal pH at Scheduled C-section in Morbidly Obese Women
The objective of our study is to evaluate the effect of CPAP on umbilical cord acid base status in morbidly obese women at the time of scheduled cesarean delivery.
- Trial name
- NCT04993651
- Testing
- CPAP
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Eastern Virginia Medical School
Obesity, Morbid Obesity
Effects of RM-493 on Energy Expenditure in Obese Individuals
Background: RM-493 is a drug that stimulates parts of the brain that control eating and metabolism. It has helped to reduce body weight and improve insulin sensitivity in lab tests.
- Trial name
- NCT01867437
- Testing
- RM-493
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Rhythm Pharmaceuticals, Inc.
Obesity, Extreme Obesity
Structured Psychoeducation for Unemployed Adolescents With Extreme Obesity in a Multicenter Observational Study Focusing on Feasibility
Obesity occurs more frequently in subjects of a lower socioeconomic status and is associated with a lower income and unemployment.
- Trial name
- STEREOplus (NCT02607995)
- Testing
- Behavioral standardized manual-based multidisciplinary routine care
- Where
- Germany
- Volunteers
- 49 people
- Sponsor
- University of Ulm
Severe Obesity, Metabolic Syndrome
Correcting GUT MicrobioTa by Combined Supplementation of FibERs and BIotiN to Improve Microbiome and Optimize Bariatric Surgery Outcomes
Bariatric surgery improves health outcomes with a maximal weight loss on average occurring 1 year after surgery but with dramatic between-subjects variability in weight loss (ranging from 20 to 160% excess weight loss) for…
- Trial name
- GUTERRING (NCT05832190)
- Testing
- Standard of care, Biotin supplement, Fiber supplement
- Where
- France
- Volunteers
- 5 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Obesity, Bariatric Surgery Candidate
Impact of Weight Loss Induced by Bariatric Surgery or Nutritional Management on Sexual Function in Men With Severe Obesity
Study of the impact of weight loss induced by surgery (interventional group) or optimal nutritional management (control group) on sexual function in men with severe obesity
- Trial name
- SexOb (NCT03528980)
- Where
- 3 sites in France
- Volunteers
- 59 people
- Sponsor
- University Hospital, Lille
Pain, Postoperative
Comparison of QLB Block and TAP Block in Morbid Obese Patients
Quadratus lumborum block (QLB) and Transversus abdominis plane (TAP) blocks are regional anesthesia techniques that are frequently used to reduce postoperative pain and are an important part of the current analgesic regimen for…
- Trial name
- NCT05820620
- Testing
- TAP block, QLB block, Control Group
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Biruni University
Morbid Obesity
Intake of Omega 3 in Morbidly Obese Patients
Ingestion of capsules of omega 3 EPA and DHA, with 1.8 g of EPA and 1.2 g DHA for morbidly obese patients, will improve the inflammatory status? C-reactive protein? Weight?
- Trial name
- NCT02113696
- Testing
- Omega 3 intake, morbid obesity
- Volunteers
- 46 people
- Sponsor
- Pontificia Universidade Católica do Rio Grande do Sul
Morbid Obesity
Remifentanil Dosing Regimes for Anesthesia in Bariatric Surgery: Characteristics of Early Recovery
Early recovery characteristics are important for patients' safety and operating room turnover. Our aim was to compare fundamental methods for dosing remifentanil during morbid obesity surgeries: a manual infusion and a…
- Trial name
- NCT04690088
- Where
- Lithuania
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Lithuanian University of Health Sciences
Morbid Obesity
SAS-J Compared to OAGB and LSG as a Treatment for Morbid Obesity
150 morbidly obese patients divided into to equal groups, group A underwent single anastomosis sleeve jejunal bypass and group B underwent mini gastric bypass, group C underwent sleeve gastrectomy.
- Trial name
- NCT03821688
- Testing
- SAS-JB, OAGB, LSG
- Where
- Egypt
- Volunteers
- 210 people
- Sponsor
- Minia University
Morbid Obesity
A High Resolution Pharmacokinetic/Pharmacodynamic Model of Propofol in Morbidly Obese Subjects
This study will determine how morbid obesity affects the distribution and metabolism of the drug propofol. The investigators hypothesize that propofol will be distributed and metabolized differently in morbidly obese subjects as…
- Trial name
- NCT01591148
- Testing
- propofol
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Stanford University