Clinical trials: Sex Differences, open to volunteers
Exercise
Sex Differences in Cold-Induced Changes in Maximal Fat Oxidation
The purpose of this research study is to determine if the cold-induced change in fat burning during exercise is different between females and males.
- Trial name
- NCT07297823
- Testing
- Cold temperature, Room Temperature
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Colorado State University
Healthy Adult
Sex Differences in Exercise-Induced Hypoalgesia
Exercise-induced hypoalgesia (EIH) refers to the reduction in pain sensitivity following acute exercise. Although aerobic exercise has been shown to induce hypoalgesia in healthy individuals, it remains unclear whether the…
- Trial name
- NCT07427979
- Testing
- Aerobic exercise using cycle ergometer
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Centro Universitario La Salle
Hemodialysis Patient
Gender-Based Differences In Dynamic Balance Among Hemodialysis Patients
Aim of the study is to investigate gender-based differences in dynamic balance in form of Timed-Up-and-Go and Five Times-sit-to-Stand-to-sit tests among hemodialysis patients.
- Trial name
- NCT07555522
- Where
- 2 sites in Egypt
- Volunteers
- 155 people
- Sponsor
- Cairo University
Autism Spectrum Disorder
Flexibility and the Predictive Brain in Autistic Males and Females
The goal of this study is to compare the neural correlates of predictive brain mechanisms during high-level social and non-social flexibility tasks, between autistic and non-autistic males and females.
- Trial name
- FLEX-PREAU (NCT06391684)
- Testing
- Social/non social; predictable vs unpredictable
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Stroke Acute, Emergency Medical Services
Sex diffErences in prehoSpitAl Stroke MEdicine
Background: Stroke is a leading cause for individual, family and societal harm with huge health-economic impact. Immediate and correct prehospital acute stroke pathway initiation is key for treatment success.
- Conditions
- Stroke Acute, Emergency Medical Services, Sex Characteristics, Prehospital Setting
- Trial name
- SESAME (NCT06865950)
- Where
- Germany
- Volunteers
- 2,000 people
- Sponsor
- Universität des Saarlandes
Autonomic Function
Understanding Individual Variability in Neuronal Signal Transmission to Target Organs in Health and Disease
The goal of this clinical trial is to evaluate the influence of parasympathetic transmission from the brain to different metabolic organs. This transmission can be blocked with the muscarinic antagonist atropine.
- Trial name
- CPB_Atropine (NCT06912048)
- Testing
- Oral glucose tolerance test with double-tracer dilution and atropine infusion
- Where
- Germany
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Ulm
Emergencies, Gender
Gender Differences and Age Related Differences in Emergency Department Admission
The goal of this observational study is to learn about difference related to age and gender in patients admitted to emergency department.
- Conditions
- Emergencies, Gender, Age Problem
- Trial name
- SADE (NCT05593692)
- Where
- Italy
- Volunteers
- 15,000 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Obstructive Sleep Apnea
A Study of Sex Differences in Neurocirculatory Control
The purpose of this study is to investigate potential sex differences in neurocirculatory control of blood pressure in patients with untreated obstructive sleep apnea (OSA).
- Trial name
- NCT06261034
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Mayo Clinic
Postoperative Delirium (POD), Sex Differences
Sex-Dependent Risk of Postoperative Delirium and Mediating Effects of Family Visits
Postoperative delirium is a common and serious complication after surgery, affecting 10-40% of older patients undergoing non-cardiac procedures.
- Trial name
- NCT07502391
- Where
- Switzerland
- Volunteers
- 471 people
- Sponsor
- Julian Rössler
Female, Male
SEx-specific Differences in Cardiac Surgery Patients (SECS).
The aim of this study is to evaluate the differences between females and males undergoing cardiac surgery. The investigators will look at perioperative factors such as adaption of body weight, previous medical history…
- Conditions
- Female, Male, Surgery, Cardiac
- Trial name
- SECS (NCT06554925)
- Testing
- Cardiac surgery
- Where
- Netherlands
- Volunteers
- 10,000 people
- Sponsor
- Jennifer Breel
Thrombosis, Exercise Training
The Effect of Team Sports on the Risk of Thrombosis in Elderly Individuals in a Municipality Setting (TEAM-AGE)
Cardiovascular disease, and especially myocardial infarction, is the most common cause of death globally, and is particularly common in older individuals.
- Conditions
- Thrombosis, Exercise Training, Sex Differences
- Trial name
- TEAM-AGE (NCT04611191)
- Testing
- Team Sports, Control
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Meningococcal Meningitis, Serogroup B, Transgender Persons
Investigating Gender and Sex Differences in Immune Responses Through Vaccination of Transgender and Cisgender Persons
Sexual differences are a well-established source of biological variation in immune system functioning, with men often displaying lower adaptive immune responses (e.g.
- Conditions
- Meningococcal Meningitis, Serogroup B, Transgender Persons, Sex Differences in Immune Response, Vaccination
- Trial name
- Vaxxygender (NCT06832514)
- Testing
- Serogroup B meningococal vaccine
- Where
- Belgium
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University Ghent
Cannabis Use Disorder
Endocannabinoids in Reward
This study will examine sex differences in the effects of cannabis in people that regularly use it. Men and women that use cannabis at least 4 days a week will participate in a study involving 3 in-person visits.
- Trial name
- NCT07815691
- Testing
- Dronabinol
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Medical University of South Carolina
Cannabis
Gender Related Differences in the Acute Effects of Delta-9-Tetrahydrocannabinol in Healthy Humans: Sub-Study II
The purpose of the study is to characterize the acute effects of cannabinoids in women relative to men and to begin probing the mechanisms that may underlie gender differences.
- Trial name
- THC-Gender-II (NCT04704271)
- Testing
- Inhaled THC
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Yale University
Red Blood Cell Transfusions, Sex Differences
Effects of Donor-recipient Sex-matched Blood Transfusion on Patient Outcomes
Red blood cell (RBC) transfusions are selected based upon matching donor and recipient blood group: donor and recipient sex are not considered when selecting blood for transfusion.
- Conditions
- Red Blood Cell Transfusions, Sex Differences, Health Services, Critically Ill Intensive Care Unit Patients
- Trial name
- SexMATTERS RCT (NCT06840756)
- Testing
- Sex-mismatched red blood cell transfusions, Sex-matched red blood cell transfusions
- Where
- 8 sites in Canada
- Volunteers
- 11,082 people
- Sponsor
- Michelle Zeller
Non-Specific Chronic Low-back Pain
Influence of Gender Difference on Knee Proprioception in Non-Specific Low Back Pain Among Young Adults
the aim of the study is to investigate the impact of gender difference on knee proprioception among non specific low back pain young adults.
- Trial name
- NCT06716515
- Testing
- digital inclinometer
- Volunteers
- 82 people
- Sponsor
- Cairo University
Obesity
Direct Measurement of Ingestive Behaviour in Relation to Sex Differences and Gastrointestinal Hormone Levels in Patients After Metabolic and Bariatric Surgery
Bariatric surgery (BS), especially procedures like Sleeve Gastrectomy (SG) and Roux-en-Y gastric bypass (RYGB), is the most effective treatment for obesity.
- Trial name
- DIBASH (NCT06538948)
- Testing
- Bariatric Surgery
- Where
- 2 sites in Switzerland
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Alcohol Use Disorder
Sex Differences in Trauma, Inflammation and Brain Function and the Implications for Treatment Efficacy in Alcohol Use Disorder
The goal of this clinical trial is to identify sex-specific biomarkers that confer greater susceptibility for Alcohol Use Disorder (AUD) and differentiate how treatment response varies by sex in people with Alcohol Use Disorder.
- Trial name
- ABSTAIN (NCT06426303)
- Testing
- Naltrexone
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Milky Kohno
Obstructive Sleep Apnea
Obstructive Sleep Apnea Among Somali-Americans
The investigators seek to advance the understanding of obstructive sleep apnea as it relates to different ethnic origins as well as sex differences.
- Trial name
- Somali OSA (NCT04124848)
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Heart Failure
AI-Based Conversational Social Support for Older Adults With Heart Failure
This three-year study aims to investigate gender differences in social frailty and evaluate the effects of an artificial intelligence (AI)-based conversational social-support intervention among older adults with chronic heart…
- Trial name
- NCT07862933
- Testing
- AI-Based Conversational Social Support, Community Social Participation
- Where
- 2 sites in Taiwan
- Volunteers
- 174 people
- Sponsor
- Chang Gung University of Science and Technology