Clinical trials: Sexual Dysfunction Female
Menopause, Vulvovaginal Atrophy
TXV13-01 Estradiol Vaginal Softgel Capsules in Treating Postmenopausal Women With Symptoms of Vulvar and Vaginal Atrophy
The study was designed to evaluate the efficacy and safety of TX-12-004-HR 10 μg in treating moderate to severe symptoms of vaginal atrophy associated with menopause after 14 days of treatment, and to estimate the effect size and…
- Conditions
- Menopause, Vulvovaginal Atrophy, Painful Intercourse, Dyspareunia
- Trial name
- NCT02449902
- Testing
- Estradiol
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- TherapeuticsMD
Female Sexual Dysfunction
Female Sexual Dysfunction Assessment and Managment of Vaginismus
The study aims at : 1. The extent female sexual dysfunction problem in community through questionnaire . 2. Compare effectiveness of two treatment options for vaginismus .
- Trial name
- NCT06755099
- Testing
- Botox, Radiofrequency
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Assiut University
Breast Carcinoma, Cancer Survivor
Fractional CO2 Laser Therapy for Survivors of Breast Malignancies
This pilot clinical trial studies how well fraction carbon dioxide (CO2) laser therapy works in treating vaginal atrophy in patients with breast cancer.
- Conditions
- Breast Carcinoma, Cancer Survivor, Cervical Carcinoma, Dyspareunia
- Trial name
- NCT03307044
- Testing
- Laser Therapy, Questionnaire Administration
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Sex Behavior
Safety Study of Transdermal Testosterone for Low Libido in Pre and Postmenopausal Women
Female sexual dysfunction (FSD) is an established side effect of Selective serotonin reuptake inhibitors (SSRIs) and serotonin noradrenalin reuptake inhibitors (SNRIs), causing symptoms such as loss of libido, arousal…
- Trial name
- TESTOSTERONE (NCT02215434)
- Testing
- Testosterone, Transdermal, Behavior
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Potiguar
Dyspareunia
Changes to Vulva, Vestibule, Urethral Meatus and Vagina 20 Weeks Post Daily Prasterone in Women With Dyspareunia
Open label study at a single research center. Subjects meeting inclusion and exclusion criteria will receive 6.5 mg prasterone vaginal inserts daily for twenty weeks.
- Trial name
- NCT03568604
- Testing
- Prasterone
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- San Diego Sexual Medicine
Vulvovaginal Atrophy
Study to Evaluate Safety and Efficacy of WC3011 (Estradiol Vaginal Cream) in Postmenopausal Women With Dyspareunia
The purpose of the study is to determine if WC3011 is safe and effective in treating the symptom of painful intercourse secondary to vulvovaginal atrophy as measured by participant self-assessment when compared to vehicle.
- Trial name
- NCT01845649
- Testing
- WC3011 Estradiol Vaginal Cream, Vehicle
- Where
- 57 sites in United States
- Volunteers
- 550 people
- Sponsor
- Warner Chilcott
Prostate Cancer, Erectile Dysfunction
Pentafecta Outcomes After Robot-assisted Laparoscopic Radical Prostatectomy
Robot-assisted laparoscopic radical prostatectomy (RALRP) is a surgical technique for the treatment of prostate cancer. The aim of this study was to report our initial experience with RALRP, by applying the concept of pentafecta.
- Conditions
- Prostate Cancer, Erectile Dysfunction, Complication of Surgical Procedure, Urinary Incontinence
- Trial name
- NCT03706508
- Testing
- Robot-assisted laparoscopic radical prostatectomy
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Benign Prostatic Hyperplasia, Lower Urinary Track Symptoms
Ejaculation-Preserving Versus Conventional Dual Wavelength Diode Laser Vaporization of the Prostate
Surgery to relieve urinary blockage caused by an enlarged prostate works well, but most men lose antegrade ejaculation afterwards, because semen passes backwards into the bladder instead of forwards.
- Conditions
- Benign Prostatic Hyperplasia, Lower Urinary Track Symptoms, Bladder Outlet Obstruction
- Trial name
- EP-TUVP (NCT07777068)
- Testing
- Conventional dual-wavelength diode laser vaporization of the prostate, Ejaculation-preserving dual wavelength diode laser vaporization of the prostate
- Where
- Iraq
- Volunteers
- 119 people
- Sponsor
- ALI KAMAL M. SAMI
Orgasmic Disorder
Female Orgasmic Disorder (FOD) and Wellbutrin XL
A recently completed multi-site double-blind placebo-controlled study found that bupropion (Wellbutrin XL) increased female orgasmic function in a group of pre-menopausal women with a diagnosis of hypoactive sexual desire…
- Trial name
- NCT00248209
- Testing
- Wellbutrin XL
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Segraves, R., T., M.D., Ph.D.
Dyspareunia
Vaginal Dilator Therapy Among Women With Gynecologic and Breast Cancers Experiencing Dyspareunia
In this randomized controlled trial, the investigators will assess the difference in mean patient-reported pain scores and sexual function between women with gynecologic or breast cancers experiencing dyspareunia (painful…
- Trial name
- NCT05129332
- Testing
- Vaginal Moisturizer, Vaginal Dilator
- Where
- 2 sites in United States
- Sponsor
- Columbia University
Endometriosis
Endometriosis: Sexual Dysfunction and Adaptation Strategies Among Couples
The primary objective of this study is to evaluate the presence/absence and description of persistent sexual troubles following surgical treatment for endometriosis for women, and their partners.
- Trial name
- DYSEXTRIOSE (NCT01402791)
- Testing
- Questionnaires
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Anxiety Disorder, Cervical Cancer
Scripted Sexual Health Informational Intervention in Improving Sexual Function in Patients With Gynecologic Cancer
This randomized pilot clinical trial studies the feasibility of a pre-operative and/or post-operative scripted sexual health informational intervention and how well it works in improving sexual function in patients with…
- Conditions
- Anxiety Disorder, Cervical Cancer, Endometrial Cancer, Female Reproductive Cancer
- Trial name
- NCT02096783
- Testing
- informational intervention, counseling intervention, questionnaire administration
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Wisconsin, Madison
Systemic Sclerosis, Vulvovaginal Signs and Symptoms
Effects of Fractional CO2 Laser Treatment on Vaginal Symptoms and Sexual Dysfunction in Women With Systemic Sclerosis
Women affected by Systemic Sclerosis and Vulvovaginal Atrophy will be submitted to a cycle composed of five vaginal CO2 laser treatment (SmartXide2 V2LR, Monalisa Touch, DEKA, Florence, Italy - Hi Scan V2LR con sonda vaginale a…
- Conditions
- Systemic Sclerosis, Vulvovaginal Signs and Symptoms, Sexual Function Disturbances
- Trial name
- SCLERDERMCO2 (NCT06231433)
- Testing
- CO2 Vaginal Laser
- Where
- Italy
- Volunteers
- 16 people
- Sponsor
- IRCCS San Raffaele
Sexual Dysfunction, Physiological
Estetrol for the Treatment of Female Sexual Arousal Disorder in Postmenopausal Women
This randomized, double-blind, placebo-controlled clinical trial investigated the effect of once daily oral administration of 20 mg estetrol monohydrate tablet for 12 weeks in postmenopausal women who experienced sexual arousal…
- Trial name
- NCT06308614
- Testing
- Estetrol
- Where
- 24 sites in United States
- Volunteers
- 82 people
- Sponsor
- Estetra
Female Sexual Arousal Disorder, Female Sexual Dysfunction (FSD)
Evaluation of the Efficacy in Increasing Sexual Arousal, Safety and Tolerability of BZ371A in Women With Sexual Arousal Disorder
Evaluation of the efficacy in increasing sexual arousal, safety and tolerability of BZ371A in gel form applied to women with sexual arousal disorder
- Trial name
- NCT06651541
- Testing
- BZ371A (0.5 ml), BZ371A (1.0 ml)
- Where
- Brazil
- Volunteers
- 174 people
- Sponsor
- Biozeus Biopharmaceutical S.A.
Pelvic Floor Disorder, Female Pelvic Floor Dysfunction
Late Side-effects After Cervical Cancer Treatment - Prevention and Treatment
Late side-effects following gynecological cancer are predominantly symptoms from the pelvic region originating from the bowels, urinary tract, lymphatic system, genitals and musculoskeletal system.
- Conditions
- Pelvic Floor Disorder, Female Pelvic Floor Dysfunction, Female Sexual Dysfunction, Female Urinary Incontinence
- Trial name
- NCT06786091
- Testing
- Pelvic floor muscle training rehabilitation
- Where
- 2 sites in Norway
- Volunteers
- 25 people
- Sponsor
- St. Olavs Hospital
Left Sided Heart Failure
Effect of Left Ventricle Diastolic Dysfunction on Outcomes in Female Cardiac Surgery Patients
The aim of this study is to evaluate the differences between males and females with LVDD, undergoing cardiac surgery. The investigators will look at perioperative factors such as body weight, body surface area, previous medical…
- Trial name
- EDISON (NCT05972356)
- Where
- Netherlands
- Volunteers
- 1,000 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Polycystic Ovary, Depression
The Effect of Polycystic Ovary Syndrome Phenotypes on Quality of Life and Sexual Function
This study was planned to examine whether different phenotypes of PCOS have an effect on quality of life, depression inventory and sexual function.
- Conditions
- Polycystic Ovary, Depression, Sexual Dysfunction
- Trial name
- PCOS (NCT06428786)
- Testing
- Female Sexual Function Index
- Where
- Turkey (Türkiye)
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Etlik Zubeyde Hanım Women's Health Care, Training and Research Hospital
BRCA Mutation, Sexual Dysfunction
Quality of Sexual Function in BRCA Mutated Women
Quality of sexual function in BRCA mutated women is investigated using SFQ28 questionnaire.
- Conditions
- BRCA Mutation, Sexual Dysfunction, Sexual Dysfunctions, Psychological, Sexual Dysfunction, Physiological
- Trial name
- BRCA_SFQ28 (NCT05456919)
- Testing
- SFQ28 Questionnaire
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Vaginismus
Botulinum Toxin Injection for Treatment of Vaginismus
According to high rate of vaginismus (about 10 percent) which leads to unconsummated marriage (about 1 percent) and low efficacy for conventional treatments such as biofeedback therapy, analgesic drugs and pain killers and…
- Trial name
- NCT00638066
- Testing
- botulinum toxin, botulinum toxin A
- Where
- Iran
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tehran University of Medical Sciences