Clinical trials: Sexual Dysfunctions
Vulvodynia, Dyspareunia
Study to Compare the Efficacy of Cognitive-behavioral Couple Therapy and Lidocaine for Provoked Vestibulodynia
Chronic pain problems involving the female reproductive system are major health concerns for all women. Poorly understood, they entail great personal and financial cost.
- Conditions
- Vulvodynia, Dyspareunia, Vestibulodynia
- Trial name
- CBCT-RCT (NCT01935063)
- Testing
- Cognitive Behavioral Couple Therapy, Topical Lidocaine
- Where
- 2 sites in Canada
- Volunteers
- 108 people
- Sponsor
- Université de Montréal
Diabetes, Erectile Dysfunction
The Prevalence of Erectile Dysfunction (ED) and ED Related Quality of Life of Diabetic Men
Adult diabetic patients aged above 20 attending the diabetic clinic of National Taiwan University Hospital are invited to attend a face to face screening and interview.
- Trial name
- NCT00173134
- Where
- Taiwan
- Volunteers
- 300 people
- Sponsor
- National Taiwan University Hospital
Penile Implantation
Prosthetics Registry and Outcomes in Urology at Duke
To establish the Prosthetics Registry and Outcomes in Urology at Duke (PROUD) which will serve as a retro- and prospective data repository that our team will use to optimize patient satisfaction, lower cost and reduce morbidity…
- Trial name
- PROUD (NCT03323645)
- Where
- United States
- Volunteers
- 190 people
- Sponsor
- Duke University
Sexual Arousal Disorder
Evaluate the Safety and Efficacy of Bremelanotide in Women With Female Sexual Arousal Disorder (FSAD)
This 8 week at home study is designed to explore efficacy endpoints and evaluate the safety of intranasal Bremelanotide in women with Female Sexual Arousal Disorder. Efficacy will be assessed vs. a parallel placebo group.
- Trial name
- NCT00425256
- Testing
- Bremelanotide
- Where
- 20 sites in United States
- Sponsor
- Palatin Technologies, Inc
Penile Injection Therapy, Erectile Dysfunction
Penile Injection Anxiety
The purpose of this study is to help us understand more about your experience with penile injection therapy. Many men become anxious when thinking about penile injections. We would like to understand more about this anxiety.
- Conditions
- Penile Injection Therapy, Erectile Dysfunction, Radical Pelvic Surgery
- Trial name
- NCT00582231
- Testing
- Questionnaires.
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Vulvar Atrophy, Vulvovaginal Signs and Symptoms
Changes in the Impact of Genitourinary Syndrome of Menopause With a Novel Nonhormonal Vulvovaginal Gel Assessed by PROMs.
The goal of this clinical trial is to improve the management of Genitourinary syndrome of menopause (GSM) to preliminary assess safety and effectivity of a novel hormone-free mucosa composition (XCMIM20m) applied topically to the…
- Conditions
- Vulvar Atrophy, Vulvovaginal Signs and Symptoms, Genitourinary Syndrome of Menopause, Quality of Life
- Trial name
- STOPGSMP (NCT06962345)
- Testing
- Hormone-free vulvovaginal gel with the tested composition XCMIM20m
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Mucosa Innovations, S.L.
Sexual Pain Disorders, Postmenopausal Symptoms
Sexual Penetration Pain in Postmenopausal Women: A Topical Botanical Drug Treatment
This study will evaluate the use of topical 5 or 10% sinecatechins, a botanical drug derived from green tea for the alleviation of sexual pain in the area around the vaginal opening (the vulvar vestibule), that is a main source…
- Conditions
- Sexual Pain Disorders, Postmenopausal Symptoms, Vulvovaginal Atrophy, Female Sexual Dysfunction
- Trial name
- NCT03682601
- Testing
- 5% sinecatechins ointment, 10% sinecatechins ointment
- Where
- 4 sites in United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- GTO Pharmaceutical, LLC
Genitourinary Syndrome of Menopause, Sexual Function Disturbances
The Ultrasonographic Assessment of Efficacy of Injectable Hyaluronic Acid for Genitourinary Syndrome of Menopause
Genitourinary syndrome of menopause (GSM) is a definition including vaginal dryness, burning, vaginal pruritus, dyspareunia and urinary symptoms which can have a negative effect on women's sexuality and quality of life.
- Trial name
- NCT05561972
- Testing
- injectable multifractional intercalated hyaluronic acid [Armonia®, Regenyal, Italy]
- Where
- Turkey (Türkiye)
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Maltepe University
Erectile Dysfunction
Clinical Trial Using Topically Applied Glyceryl Trinitrate (GTN) for the Treatment of Erectile Dysfunction
To demonstrate the efficacy of various doses of MED2005 versus placebo in male patients with clinically diagnosed erectile dysfunction, and to evaluate the long-term efficacy and safety (12 months) of MED2005.
- Trial name
- NCT03813992
- Testing
- MED2005
- Where
- 53 sites in Bulgaria, Czechia and 7 more
- Volunteers
- 1,005 people
- Sponsor
- Futura Medical Developments Ltd.
Stigma, Social, Gays
An LGBT-Competency Program for Mental Health Professionals in Romania
Lesbian, gay, bisexual and transgender individuals (LGBTI) present increased morbidity compared to the general population, which is attributed to healthcare discrimination and lack of LGBT-specific expertise, especially in…
- Conditions
- Stigma, Social, Gays, Lesbians, Bisexuals
- Trial name
- NCT03602222
- Testing
- Mobile web training LGBT mental health, In-person training LGBT mental health
- Where
- Romania
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Rutgers University
Menopause, Vulvovaginal Atrophy
TXV13-01 Estradiol Vaginal Softgel Capsules in Treating Postmenopausal Women With Symptoms of Vulvar and Vaginal Atrophy
The study was designed to evaluate the efficacy and safety of TX-12-004-HR 10 μg in treating moderate to severe symptoms of vaginal atrophy associated with menopause after 14 days of treatment, and to estimate the effect size and…
- Conditions
- Menopause, Vulvovaginal Atrophy, Painful Intercourse, Dyspareunia
- Trial name
- NCT02449902
- Testing
- Estradiol
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- TherapeuticsMD
Erectile Dysfunction
Fundus Oculi and Erectile Dysfunction
The purpose of this study is to evaluate the correlation between fundus oculi's vascularization in patients with erectile dysfunction and not, and, in the same patients, before and after using drugs for ED.
- Trial name
- NCT02845765
- Testing
- Dynamic Vessel Analyzer (DVA), Phosphodiesterase type 5 Inhibitor (PDE5I)
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ospedale San Raffaele
Premature Ejaculation
Effect of Exercise on Premature Ejaculation
Premature ejaculation (PE) is one of the prevalent disorders in men; its leading sequel such as lack of self-confidence, anxiety, depression and unsatisfactory intercourse in men and their partners.
- Trial name
- NCT02984592
- Testing
- physical exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ankara Training and Research Hospital
Erectile Dysfunction, Testosterone Deficiency
Effect of Testosterone in Men With Erectile Dysfunction
The purpose of this placebo-controlled study is to determine if testosterone replacement therapy, administered by transdermal gel, can improve the response to sildenafil (Viagra R) treatment in men who have erectile dysfunction…
- Conditions
- Erectile Dysfunction, Testosterone Deficiency, Diabetes
- Trial name
- TED (NCT00512707)
- Testing
- Sildenafil citrate (open label), Testosterone gel
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Boston University
Gender Dysphoria
Development of Effective, Opioid Sparing Techniques for Peri-operative Pain Management of Transgender Patients Undergoing Gender Affirming Surgeries
This study will compare the current standard-of-care pain treatment regimen options that are available to patients who undergo gender-affirming surgery.
- Trial name
- NCT04979338
- Testing
- Ultrasound guided Continuous Infraclavicular Brachial Plexus Block, Ultrasound guided Continuous Femoral Nerve Block, Ultrasound guided Pudendal Nerve Block
- Where
- United States
- Volunteers
- 640 people
- Sponsor
- Cedars-Sinai Medical Center
Vulvodynia, Dyspareunia
Use of Topical Testosterone and Estrogen vs Estrogen Alone in Vulvodynia: a Randomized Controlled Trial
We are looking to see if patients using both topical testosterone and estrogen will have a greater improvement in pain with vaginal penetration compared to those using topical estrogen alone.
- Conditions
- Vulvodynia, Dyspareunia, Lichen Sclerosus of Vulva
- Trial name
- NCT07260825
- Testing
- Estradiol 0.01% Vag Cream, testosterone 0.1% and estradiol 0.01% vaginal cream
- Where
- 2 sites in United States
- Volunteers
- 44 people
- Sponsor
- TriHealth Inc.
Erectile Dysfunction
Clinical Trial of Topically-applied Glyceryl Trinitrate (GTN) for the Treatment of Erectile Dysfunction (ED)
This study is designed to evaluate the efficacy and safety of MED2005, a topically applied glyceryl trinitrate (GTN) gel administered to the penis of male subjects self-diagnosed with erectile dysfunction (ED) immediately before…
- Trial name
- NCT02495467
- Testing
- Glyceryl trinitrate
- Where
- United Kingdom
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- Futura Medical Developments Ltd.
Pelvic Radiotherapy, Gynecological Cancer
Laser Therapy Following Radiotherapy for Gynecological Cancer
Women with a history of pelvic radiotherapy due to gynecological cancer, will receive laser therapy for the management of genitourinary syndrome of menopause.
- Conditions
- Pelvic Radiotherapy, Gynecological Cancer, Dyspareunia, Vaginal Dryness
- Trial name
- NCT03714581
- Testing
- Microablative Fractional CO2 Laser Therapy
- Where
- Greece
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Food Addiction, Sexual Addiction
Physiopathology of Behavioral Addictions and Biomarkers
The goal of this observational study is to evaluate the expression of miR-10a-5p in the blood in patients with sexual addiction or food addiction.
- Trial name
- MiRACle (NCT07830680)
- Testing
- blood sampling
- Where
- France
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Penile Induration, Penile Diseases
Stem Cell Treatment of Peyronie´s Disease.
Purpose of the project is to investigate if a single injection of autologous stromal vascular fraction into and around plaque is a safe and suitable treatment.
- Trial name
- NCT04771442
- Testing
- Stromal vascular fraction
- Where
- Denmark
- Volunteers
- 22 people
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark