Clinical trials: Sexually Transmitted Infection
HIV, Sexually Transmitted Infections
Connect 'n Unite: Couples-Based HIV/STI Prevention for Drug-Involved, Black MSM
The study has the following primary aims: (1) to test whether participants assigned to CNU (a 7-session, manualized intervention entitled "Connect 'n Unite") engage in lower HIV/STI behavioral risk compared to participants…
- Trial name
- CNU (NCT01394900)
- Testing
- CNU Intervention, WP Intervention
- Where
- United States
- Volunteers
- 424 people, healthy volunteers welcome
- Sponsor
- Columbia University
HIV Infections, Sexually Transmitted Infections
Reducing Disparities in Rural HIV Prevention
HIV and Sexually Transmitted Infection (STI) rates are increasing in rural areas including rural Colorado. Many rural residents find it difficult to access HIV and STI prevention services.
- Trial name
- NCT05319613
- Testing
- Virtual clinical visits with home lab kits and mailed HIV PrEP
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Sexual Behavior, Unprotected Sex
Protecting Our Future Generation: Promotion of Protective Sexual Health Practices Among Native American Youth and Young Adults Through an Assets-based Self-care Intervention
The aim of this research protocol is to test the efficacy of a self-care intervention through a randomized controlled trial (RCT), for increasing protective sexual health behaviors among youth in the participating Native American…
- Conditions
- Sexual Behavior, Unprotected Sex, Gonorrhea, Chlamydia
- Trial name
- NCT03895320
- Testing
- Sexual Health Risk Assessment, Sexual Health Score, Sexual Health Messaging
- Where
- United States
- Volunteers
- 219 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Sexually Transmitted Diseases, Gonorrhea
Evaluation of EVO100 for Prevention of Urogenital Chlamydia Trachomatis and Neisseria Gonorrhoeae Infection
This study will evaluate whether EVO100 vaginal gel prevents the sexual transmission of CT and GC infection
- Conditions
- Sexually Transmitted Diseases, Gonorrhea, Chlamydia
- Trial name
- EVOGUARD (NCT04553068)
- Testing
- EVO100
- Where
- 98 sites in United States
- Volunteers
- 1,892 people, healthy volunteers welcome
- Sponsor
- Evofem Inc.
Substance Use, HIV Infections
Kentucky Communities and Researchers Engaging to Halt the Opioid Epidemic (CARE2HOPE)
This study will test the effects of an intervention to reduce substance use and related harms among people leaving rural jails or otherwise involved in the criminal justice system.
- Conditions
- Substance Use, HIV Infections, HCV Infection, Sexually Transmitted Infections (Not HIV or Hepatitis)
- Trial name
- NCT04134767
- Testing
- Health Linkage, Overdose Education
- Where
- United States
- Volunteers
- 234 people, healthy volunteers welcome
- Sponsor
- April M Young
Health Behavior, Health Care Utilization
Evaluation of the SafeSpace App Intervention
The goal of this study is to evaluate the impact of SafeSpace Sexual Health App, an innovative sexual health promotion program focused on reducing sexual risk factors and promoting sexual and reproductive health and wellbeing…
- Conditions
- Health Behavior, Health Care Utilization, Unprotected Sex, Sexually Transmitted Infections
- Trial name
- SafeSpace (NCT06043596)
- Testing
- SafeSpace Sexual Health, SafeSpace General Health
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Child Trends
HIV Infections, Sexually Transmitted Infection
User-friendly HIV Testing and Counseling Services
Multicenter cohort study of individuals reporting behavioral risks of HIV acquisition, recruited among those presenting for testing for HIV and other sexually transmitted infections.
- Conditions
- HIV Infections, Sexually Transmitted Infection, Hepatitis B, Chronic, Hepatitis C
- Trial name
- NCT04585165
- Where
- 6 sites in Thailand
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Institut de Recherche pour le Developpement
HIV, Sexually Transmitted Infections
Transgender Men and HIV in Uganda: PrEP Uptake and Persistence
Transgender men (trans men; assigned female sex at birth but identify as male) are generally thought to be at low risk of HIV acquisition, perhaps because of the assumption that they have sex with cis-gender women.
- Conditions
- HIV, Sexually Transmitted Infections, PrEP, Transgender Men
- Trial name
- NCT04867798
- Testing
- Lamivudine-Tenofovir 300 Mg-300 Mg Oral Tablet
- Where
- Uganda
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Makerere University
Contraception, Prevention of Sexually Transmitted Infections
Evaluation of Polyurethane Male Condoms
The clinical study will compare two lubricated polyurethane male condoms of different thickness with a marketed lubricated control male condom made of natural rubber latex.
- Trial name
- NCT04622306
- Testing
- Control Latex Condom C, Polyurethane Condom A, Polyurethane Condom B
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Sagami Rubber Industries Co., Ltd.
HIV Infections, Sexually Transmitted Diseases
Integrating Enhanced HIV PrEP Into a STI Clinic in Lilongwe
This is a prospective cohort study evaluating acceptability, feasibility, and effectiveness of integrating HIV pre-exposure prophylaxis (PrEP) into a sexually transmitted infection (STI) clinic alongside assisted partner…
- Conditions
- HIV Infections, Sexually Transmitted Diseases, Blood-Borne Infections, Communicable Disease
- Trial name
- NCT05307991
- Testing
- PrEP, STI testing, Assisted partner notification
- Where
- Malawi
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
HIV Infection Primary, Hepatitis, Viral, Human
Seville Cohort of People at Substantial Risk for HIV Infection on Pre-exposure Prophylaxis
Pre-exposure prophylaxis (PrEP) based on tenofovir represents a considerably new preventive intervention that has shown to significantly decrease the number of HIV infections while it enables early diagnosis of HIV and other…
- Conditions
- HIV Infection Primary, Hepatitis, Viral, Human, Sexually Transmitted Infections, Excluding HIV and Hepatitis
- Trial name
- SeVIHPrEP (NCT05492565)
- Testing
- Tenofovir Disoproxil Fumarate 300 MG Oral Tablet
- Where
- Spain
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Hospitales Universitarios Virgen del Rocío
HIV Infections, Sexually Transmitted Infections
Uptake of Medical Male Circumcision Among Men With Sexually Transmitted Infections
The intervention includes provision of transport reimbursement for men who will undergo voluntary medical male circumcision (VMMC), intensified health education by a VMMC mobilizer and a male and female VMMC champion and use of a…
- Trial name
- VMMC-RITe (NCT04677374)
- Testing
- Standard of care, Intensified Health Education, SMS/telephonic Tracing
- Where
- Malawi
- Volunteers
- 2,242 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Sexually Transmitted Infection, Gonorrhea Female
Use of a Rapid Test for Gonorrhea & Chlamydia for Women Presenting With Possible Sexually Transmitted Infections
The purpose of this study is to evaluate the effect of utilizing a rapid turnaround CT/NG test on treatment of female patients in the emergency department or urgent care setting with possible STIs.
- Conditions
- Sexually Transmitted Infection, Gonorrhea Female, Chlamydia Females
- Trial name
- NCT03098394
- Testing
- Cepheid Xpert CT/NG Rapid Turnaround Test, Polymerase chain reaction (PCR)
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
HIV Infections, Sexually Transmitted Diseases
Reducing HIV Vulnerability Through A Multilevel Life Skills Intervention For Adolescent Men
The investigators propose to deliver and test a life skills intervention targeting the key domains that fuel HIV disparities among adolescent (ages 13-18) same-sex attracted men in the United States.
- Conditions
- HIV Infections, Sexually Transmitted Diseases, Sexual Behavior, Adolescent Behavior
- Trial name
- NCT03155841
- Testing
- Life Skills Coaching, Community Resources
- Where
- 2 sites in United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Sexually Transmitted Diseases, HIV Infections
Community Influences Transitions in Youth Health (CITY) Health II - Center for the Study of Community Health
The purpose of this protocol is to develop and evaluate an HIV prevention Entertainment Education (EE) intervention aimed at reaching underserved, at-risk African Americans, aged 18-25 years, living in disadvantaged urban…
- Trial name
- CH-II (NCT04320186)
- Testing
- Entertainment education, video
- Where
- United States
- Volunteers
- 334 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Chlamydia Infections, Gonorrhea
Extraordinarily Fun Training Project in Compulsory Secondary Education - Sexually Transmitted Infections
Project FEDE-ITS will improve the STI knowledge and its treatment, of adolescents in the 1st and 2nd year of compulsory secondary education in the intervention group compared to compared to the control group, and will modify the…
- Conditions
- Chlamydia Infections, Gonorrhea, Syphilis Infection, Human Immunodeficiency Virus (HIV)
- Trial name
- FEDE-ITS (NCT05727033)
- Testing
- Participatory teaching group
- Where
- 4 sites in Spain
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Hiv, Sexually Transmitted Infection
Expanding PrEP By Embedding Unannounced SNAPS Navigators in High STI Testing Clinical Sites
The goal of this study is to assess the impact of an intervention, known as SNAPS, to expand Preexposure Prophylaxis (PrEP) prescriptions at Health + Hospitals (H+H)/Bellevue.
- Trial name
- NCT04207151
- Testing
- SNAPS intervention
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
HIV/AIDS, HIV Infections
Health and Justice: A Continuum of Care for HIV and SU for Justice-Involved Young Adults (PHASE 2)
This research study proposes to embed HIV testing outreach workers from a young adult focused medical and HIV treatment program into an alternative sentencing program to deliver a new service delivery model (Link2CARE) that…
- Conditions
- HIV/AIDS, HIV Infections, Substance Use, Substance Abuse
- Trial name
- NCT03369249
- Testing
- Link2CARE
- Where
- United States
- Volunteers
- 307 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Human Papillomavirus
Natural History of HPV Infection in Men: The HIM Study
The purpose of this study is to learn about the natural history of Human Papillomavirus (HPV) infection in men. The study will also find out what factors are linked to HPV in men including other sexually transmitted diseases…
- Trial name
- NCT00786760
- Testing
- Cohort: 3000 men examined every 6 months for 4 years., Pilot study: 150 men examined every 6 months for 4 years.
- Where
- United States
- Volunteers
- 1,431 people, healthy volunteers welcome
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
HIV, Mental Health
Stepped Care for Youth Living With HIV
Optimizing the HIV Treatment Continuum with a Stepped Care Model for Youth Living with HIV (YLH) aims to achieve viral suppression among YLH.
- Conditions
- HIV, Mental Health, Illicit Substance Use, Sexually Transmitted Infections (STI)
- Trial name
- NCT03109431
- Testing
- Level 1, Level 2, Level 3
- Where
- 2 sites in United States
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles