Clinical trials: Sexually Transmitted Infection (STI)
HIV Infection, Gastrointestinal Symptoms
A Controlled Trial to Evaluate the Effects of GanedenBC30 on the Immune System
Improvement in the rate of bacterial translocation may lead to a decrease in a chronic inflammatory response thereby decreasing CD4 destruction and HIV proliferation.
- Trial name
- NCT01184456
- Testing
- GanedenBC30, GBI-30, PTA-6086
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- AIDS Healthcare Foundation
Hiv
Tui na for Peripheral Neuropathy Among People With HIV
Peripheral neuropathy (PN) is a common neurological complication in people with human immunodeficiency virus (PHIV) with no Food and Drug Administration-approved treatment.
- Trial name
- NCT05596123
- Testing
- Therapeutic Chinese foot massage
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Houston Downtown
HIV, Stress Disorder
CBSM Intervention Via mHealth to Ameliorate HIV-related Fatigue
The purpose of this study is to create a smartphone, tablet and web-based application to help people deal with stress. Stress often increases fatigue in people with HIV infection, so successfully dealing with stress could help…
- Conditions
- HIV, Stress Disorder, Human Immunodeficiency Virus, Fatigue
- Trial name
- NCT03149094
- Testing
- CBSM-SMI, CBSM-SMI control
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Medical University of South Carolina
Genital Wart
Comparison Between Tuberculin Vaccine and Cryotherapy in Genital Wart Patients
Cutaneous and genital warts are common dermatological conditions caused by Human Papilloma Virus. Although it is a benign condition it causes disfigurement, has tendency to collect, can be transmitted to others, this makes…
- Trial name
- NCT03153566
- Testing
- tuberculin, cryotherapy
- Volunteers
- 45 people
- Sponsor
- Assiut University
HIV Infections
Evaluating the Safety and Tolerability of Etravirine in HIV-1 Infected Infants and Children
Non-nucleoside reverse transcriptase inhibitors (NNRTIs) are widely used as part of combination antiretroviral therapy (ART) for infants and children, but NNRTI resistance is increasing, leading to treatment failure.
- Trial name
- NCT01504841
- Testing
- Etravirine (ETR)
- Where
- 11 sites in United States, Brazil and 1 more
- Volunteers
- 26 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Sexually Transmitted Infections, Pregnancy, Unplanned
Optimizing a Multi-Modal Intervention to Reduce Health-Risking Sexual Behaviors: Component Selection
The goal of this project is to evaluate the components of the app-based intervention Mission Wellness to reduce health-risking sexual behaviors (HRSBs; e.g., condom non-use, multiple sexual partners) in active-duty members of the…
- Conditions
- Sexually Transmitted Infections, Pregnancy, Unplanned, Military Personnel
- Trial name
- NCT04661566
- Testing
- Basic Education ("Education"), Narrative Videos ("Narratives"), Skills Building Videos ("Skills")
- Where
- United States
- Volunteers
- 549 people, healthy volunteers welcome
- Sponsor
- Uniformed Services University of the Health Sciences
Cervical Cancer, Condylomata Acuminata
An Immuno-bridging Study of a Nonavalent HPV Vaccine (E.Coli) in Healthy Population Aged 9-17 vs Aged 18-26 Years Old
This is a open label clinical trial to evaluate the safety and immunogenicity of a Recombinant Human Papillomavirus Nonavalent (Types 6,11,16,18,31,33,45,52,58)Vaccine(E.Coli) manufactured by Xiamen Innovax Biotech CO., Ltd., in…
- Trial name
- NCT05056402
- Testing
- 3 doses of the Recombinant Human Papillomavirus Nonavalent (Types 6,11,16,18,31,33,45,52,58 )Vaccine(E.Coli), 2 doses of theRecombinant Human Papillomavirus Nonavalent (Types 6,11,16,18,31,33,45,52,58 )Vaccine(E.Coli)
- Where
- China
- Volunteers
- 1,382 people, healthy volunteers welcome
- Sponsor
- Xiamen University
HIV
Leukapheresis to Obtain Plasma or Lymphocytes for Studies of HIV-infected Patients, Including Long-term Non-progressors
This study will collect white blood cells and plasma for research on how the immune system controls HIV infection. The immune system of a very small group of people with HIV, called non-progressors, has been able to control HIV…
- Trial name
- NCT00029445
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV-1 Infected Adults With Chronic HIV-1 Infection
Enhancement by Poly-ICLC During HIV-1 Infection
This study involves researching new approaches to treating HIV infection. Currently, HIV infection is treated with combinations of drugs called antiretrovirals.
- Trial name
- Poly-ICLC (NCT02071095)
- Testing
- Arm A: Poly-ICLC, Arm B: Normal Saline
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Nina Bhardwaj
Human Immunodeficiency Virus (HIV)
An Italian Observation of Antiretroviral Treatment in Participants Taking Darunavir/ Cobicistat Plus Emtricitabine and Tenofovir Alafenamide Fumarate
The purpose of this study is to describe the effectiveness of Darunavir/ Cobicistat/ Emtricitabine/ Tenofovir Alafenamide (D/C/F/TAF), measured as virological response at Week 48 as per Food and Drug Administration (FDA) snapshot…
- Trial name
- DIAMANTE (NCT03577470)
- Testing
- D/C/F/TAF Fixed-Dose Combination (FDC)
- Where
- 18 sites in Italy
- Volunteers
- 246 people
- Sponsor
- Janssen-Cilag S.p.A.
HIV Infections
Antiretroviral Treatment Taken 4 Days Per Week Versus Continuous Therapy 7/7 Days Per Week in HIV-1 Infected Patients
The trial is an open-label, multicenter, prospective, randomized trial in 2 parallel groups, evaluating at W48, the non-inferiority of antiretroviral treatment taken 4 consecutive days a week versus continuous therapy, in HIV…
- Trial name
- QUATUOR (NCT03256422)
- Testing
- Treatment discontinuation
- Where
- 63 sites in France
- Volunteers
- 640 people
- Sponsor
- ANRS, Emerging Infectious Diseases
Human Immunodeficiency Virus
Trial to Assess the Continued Safety of and Adherence to a Vaginal Ring Containing Dapivirine in Women
HIV Open-label Prevention Extension (HOPE).
- Trial name
- NCT02858037
- Testing
- Dapivirine Vaginal Ring
- Where
- 17 sites in Malawi, South Africa and 2 more
- Volunteers
- 1,456 people, healthy volunteers welcome
- Sponsor
- International Partnership for Microbicides, Inc.
Human Immunodeficiency Virus, Human Papillomavirus-Related Anal Squamous Cell Carcinoma
Anal High-risk HPV, HSIL, and Microbiome Among Hispanic Peoples Living With HIV (PLWH)
The study evaluates if there is relationship between the kinds of bacteria living in the anus (also known as the anal microbiome) and the risk of human papillomavirus (HPV) infection or HPV-related pre-cancer (high-grade squamous…
- Conditions
- Human Immunodeficiency Virus, Human Papillomavirus-Related Anal Squamous Cell Carcinoma, High-Grade Squamous Intraepithelial Lesions
- Trial name
- ULACNet-104 (NCT06651957)
- Testing
- Biospecimen Collection, Questionnaires
- Where
- 3 sites in United States, Mexico and 1 more
- Volunteers
- 217 people
- Sponsor
- University of California, San Francisco
HIV Infections, Mental Health
Testing the WeCare Intervention to Address Mental Health and Medication Adherence Challenges Among MSM in South Africa
The goal of this clinical trial is to learn if the WeCare intervention-an adapted Friendship Bench program that integrates problem-solving therapy, minority-stress-informed content, and explicit PrEP/ART adherence skills-improves…
- Trial name
- NCT07226323
- Testing
- WeCare, Standard of Care
- Where
- South Africa
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Emory University
HIV Prevention, Pre-exposure Prophylaxis
Hybrid Evaluation of a Home-based HIV Pre-exposure Prophylaxis Program
The study's aim is to implement a home-based PrEP (HB-PrEP) monitoring system (self-collected blood and extragenital specimens at home and telehealth follow-up) into a large, urban sexual health clinic while also evaluating the…
- Conditions
- HIV Prevention, Pre-exposure Prophylaxis, STI
- Trial name
- HOT4PrEP (NCT05856942)
- Testing
- Health service - home-based PrEP monitoring
- Where
- United States
- Volunteers
- 458 people, healthy volunteers welcome
- Sponsor
- University of Washington
Head and Neck Cancer, Precancerous Condition
Induction Chemotherapy Followed By Cetuximab and Radiation in HPV-Associated Resectable Stage III/IV Oropharynx Cancer
RATIONALE: Drugs used in chemotherapy, such as paclitaxel and cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT01084083
- Testing
- cetuximab, intensity-modulated radiation therapy (IMRT), Paclitaxel
- Where
- 121 sites in United States
- Volunteers
- 90 people
- Sponsor
- Eastern Cooperative Oncology Group
HIV
Exploring HIV Entry Blockade as a Pre-exposure Prophylaxis Strategy in Women
Pre-exposure prophylaxis (PrEP) is an HIV prevention strategy in which HIV medicines are used by a person before they are exposed to HIV in order to decrease his or her chance of getting infected.
- Trial name
- MVC-PREP (NCT01749566)
- Testing
- maraviroc
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Emory University
HIV Infections
SEPA+PrEP-Women Pilot Trial for HIV Prevention Among Women at Risk for HIV
The purpose of this randomized pilot trial is to evaluate the preliminary efficacy of SEPA+PrEP-Women (Salud/Health, Educación/Education, Prevención/Prevention, Autocuidado/Self-Care plus Pre-Exposure Prophylaxis [PrEP]).
- Trial name
- NCT07864766
- Testing
- SEPA+PrEP Women
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Miami
Human Immunodeficiency Virus
Study in HIV1-Positive, Virosuppressed Patients Currently inTreatment With Ritonavir-Boosted Protease Inhibitors (PI/r) Starting Cobicistat-Boosted Darunavir (DRV/c - Rezolsta)
The purpose of this study is to describe the effectiveness of darunavir/cobicistat (DRV/c)-based regimens, measured as maintenance of virological suppression 48 weeks after baseline, defined as the day when the treatment with…
- Trial name
- STORE (NCT02926456)
- Volunteers
- 337 people
- Sponsor
- Janssen-Cilag S.p.A.
HIV Infections
Pilot Study Evaluating Interruption of Enfuvirtide (Fuzeon, T20) in Patients With Enfuvirtide Resistance
The goal of this study is to examine whether enfuvirtide (T20, Fuzeon) has continued anti-HIV activity in patients experiencing an incomplete virologic response to an enfuvirtide-based regimen.
- Trial name
- NCT00187551
- Testing
- Interruption of enfuvirtide, enfuvirtide interrupton
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of California, San Francisco
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