Clinical trials: Shear Wave Elastography
Obesity, Fatty Liver
Impact of Bariatric Surgery on the Evolution of Nonalcoholic Fatty Liver Disease: a Comparative Clinical Trial Between Sleeve Gastrectomy and Gastric Bypass
Aim: To compare prospectively two bariatric surgery techniques: sleeve gastrectomy (SG) vs gastric bypass (GB) in the evolution of nonalcoholic fatty liver disease (NAFLD) measured by the transient elastography in the first year.
- Trial name
- NCT02394353
- Testing
- Transient hepatic elastography
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ministry of Health, Brazil
Masseter Muscle Spasm
Assessment of Correlation Between Changes of Shear Wave Elastography and Surface Electromyogram of the Masseter
Diagnoses and follow up of muscles diseases lack imaging. Severity assessment of masticatory dysfunction and follow up of treatment effectiveness is currently based only on clinical features.
- Trial name
- EVEREST (NCT02425839)
- Testing
- Ultrasound exam by Supersonic Shear Imaging® technique, EMG examination by electromyograph Keypoint system
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Arterial Hypertension, Chronic Kidney Disease, Primary Aldosteronism
Kidney Stiffness Measured by Ultrasound in Patients With High Blood Pressure and Healthy Volunteers
High blood pressure (hypertension) is a leading cause of kidney damage, but detecting early kidney changes remains challenging with currently available tools.
- Conditions
- Arterial Hypertension, Chronic Kidney Disease, Primary Aldosteronism, Arterial Stenosis
- Trial name
- K-STRESS (NCT07914075)
- Where
- Italy
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera di Padova
Diabetes Mellitus, Type 2, Non-alcoholic Fatty Liver Disease
Efficacy Study of Diacerein on Glycemic Control and Liver Fat in Type 2 Diabetes Subjects
This study is conducted to test the hypothesis that in uncontrolled type 2 diabetic adults treatment with diacerein will improve glycemic control and will reduce liver fat within a 24 month period.
- Trial name
- DGCLFT2DM (NCT02242149)
- Testing
- Diacerein
- Where
- Brazil
- Volunteers
- 84 people
- Sponsor
- Universidade Federal do Rio de Janeiro
NAFLD, NASH - Nonalcoholic Steatohepatitis
The Franciscus Obesity NASH Study
The purpose of this study is to evaluate Non-Alcoholic Fatty Liver Disease (NAFLD) and Non-Alcoholic Steatohepatitis (NASH) changes in terms of steatosis and elasticity in patients with morbid obesity 1, 3 and 5 years after…
- Conditions
- NAFLD, NASH - Nonalcoholic Steatohepatitis, Obesity, Morbid
- Trial name
- FONS (NCT05499949)
- Testing
- NASH screening, Cardiac dysfunction screening, Liver biopsy
- Where
- Netherlands
- Volunteers
- 300 people
- Sponsor
- Franciscus Gasthuis
Solid Neoplasm
An Investigational Device (Millar Mikro-Tip Catheter) and Imaging Scan (Shear Wave Elastography) in Measuring Tumor Pressure and Stiffness in Patients With Solid Tumors Undergoing Ultrasound-Guided Biopsy
This trial studies how well a Millar Mikro-tip catheter and shear wave elastography measure pressure and stiffness inside tumors among patients with solid tumors undergoing an ultrasound-guided biopsy.
- Trial name
- NCT04054154
- Testing
- Shear Wave Elastography, Tumor Interstitial Fluid Pressure Measurement
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- M.D. Anderson Cancer Center
Nonalcoholic Fatty Liver, Nonalcoholic Steatohepatitis
Conditionally Increased Output (CIO) Enhanced Ultrasound System
This study aims to assess possible bioeffects that may be caused by the use of shear wave elastography (SWE) with conditionally increased acoustic output pressure (CIO).
- Conditions
- Nonalcoholic Fatty Liver, Nonalcoholic Steatohepatitis, Fatty Liver
- Trial name
- NCT05792423
- Testing
- GE ultrasound system with increased acoustic output settings
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Chronic Viral Hepatitis
Agreement and Reliability of Transient Elastography
The aim of this study is to assess agreement, smallest detectable change, and reliability of repeated measurements of liver stiffness of transient elastography in patients with chronic viral hepatitis, and to explore factors…
- Trial name
- HEPSCAN (NCT05686785)
- Testing
- Transient elastography
- Where
- Sweden
- Volunteers
- 300 people
- Sponsor
- Lund University
Hepatitis C, Fibrosis
The Prevalence and Severity of HCV Infection in Thalassemia Major and Thalassemia Intermedia in Siriraj Hospital
The primary objective is to assess the prevalence and genotypes of HCV infection in thalassemia major and thalassemia intermediate patients who have received blood transfusion in the Department of Medicine, Faculty of Medicine…
- Conditions
- Hepatitis C, Fibrosis, Thalassemia
- Trial name
- NCT02904252
- Testing
- Transient elastography
- Where
- Thailand
- Volunteers
- 158 people
- Sponsor
- Mahidol University
Non-alcoholic Fatty Liver Disease (NAFLD)
NASH Patient's Itinerary: Comparison of Strategies for Screening, Referring and Management of Diabetic Patients
Non-alcoholic fatty liver disease (NAFLD) is a highly prevalent, underdiagnosed, health system burden and impacts on quality of life including comorbidities in the affected population.
- Trial name
- NASH-PI (NCT06688149)
- Testing
- Derivation algorithms
- Where
- 4 sites in Germany, Greece and 1 more
- Volunteers
- 536 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
NAFLD
Transient Elastography of the Liver ( Fibroscan ) and Bariatric Surgery
To evaluate the effect of Bariatric surgery on the extent of liver fat and liver fibrosis and on different metabolic parameters in patients undergoing sleeve gastrectomy surgery.
- Trial name
- NCT02122263
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Ziv Hospital
Short Bowel Syndrome, Intestinal Failure
Effect of Parenteral Support on FibroScan in Short Bowel Syndrome
Home Parenteral Support (HPS) is a life-sustaining treatment for patients with short bowel syndrome and intestinal failure. This study aims to investigate how administration of parenteral support affects FibroScan results in…
- Conditions
- Short Bowel Syndrome, Intestinal Failure, Liver Diseases
- Trial name
- NCT07206004
- Testing
- Fibroscan
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Shear Wave Elastography, Pancreatic Diseases
Shear Wave Elastography in Diagnosis of Inflammatory and Malignant Pancreatic Diseases
Only a few studies that have assessed the normal range value for pancreatic stiffness, inflammatory and malignant pancreatic lesions, shear wave velocities of healthy parenchyma, acute and chronic pancreatitis, malignant lesions…
- Trial name
- NCT04964648
- Testing
- shear wave elastography
- Volunteers
- 100 people
- Sponsor
- Assiut University
Pleural Diseases
The Efficacy of Shear-wave Elastography-guided Biopsy for Diagnosis in Pleural Disease
To investigate the information from shear-wave elastography on pleural tissues will improve the diagnosis of pleural diseases, as to increase the diagnostic yield in ultrasound-guided transthoracic pleura biopsy.
- Trial name
- NCT06226909
- Testing
- different types of ultrasound technique
- Where
- Taiwan
- Volunteers
- 234 people
- Sponsor
- National Taiwan University Hospital
Healthy, Healthy Individuals (Controls)
Protocol for Tongue Elastography and Ultrasound Markers
The purpose of this observational is to methodologically assess the standardisation and reliability of a protocol of ultrasound lingual markers, including tongue shear-wave elastography, attenuation indexes, and echo intensity in…
- Trial name
- NCT07024069
- Testing
- Tongue ultrasound via submental approach
- Where
- Belgium
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Haute Ecole Bruxelles-Brabant
Postpartum Hemorrhage
Prediction of Uterine Atony After Vaginal Delivery by Elastography
Prospective study evaluating the feasibility of shear-wave elastography of the uterus during the third stage of labour and following placental delivery.
- Trial name
- NCT04267783
- Testing
- Shear wave elastography
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Ulnar Nerve Compression
US and Shear Wave Elastography in Cubital Tunnel Syndrome
This study aims to assess the role of US and SWE in diagnosis of CuTS and localization of its underlying etiology and verifying whether it can be diagnosed and graded based on US findings, especially quantitaive ulnar nerve…
- Trial name
- NCT06090877
- Testing
- US and shear wave elstography
- Volunteers
- 50 people
- Sponsor
- Assiut University
Psoriasis, Liver Fibrosis
MTX-related Liver Toxicity in Psoriasis Patients, Using Ultrasound-based Techniques as a Diagnostic Tool
Methotrexate is one of the commonly used conventional systemic treatment for moderate to severe psoriasis as well as psoriatic arthritis.
- Trial name
- NCT04168619
- Testing
- Discontinue methotrexate, Medication depends on clinical judgement
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- The University of Hong Kong
Liver Fibrosis
Prospective Evaluation of FibroScan in Patients Treated With Methotrexate
The aim of this study is to evaluate liver fibrosis using FibroScan and biochemical markers in patients treated with methotrexate.
- Trial name
- Methoscan (NCT00673101)
- Where
- France
- Volunteers
- 1,871 people
- Sponsor
- Association HGE CHU Bordeaux Sud
Rotator Cuff Injuries, Rotator Cuff Tear
Ultrasound and Shear Wave Elastography for Assessment of the Quality of Rotator Cuff Muscles
Rotator cuff disorders are among the most frequent musculoskeletal causes of shoulder pain, weakness, and limited movement. In many individuals with rotator cuff disease, the damaged muscles gradually shrink (muscle atrophy) and…
- Conditions
- Rotator Cuff Injuries, Rotator Cuff Tear, Muscular Atrophy, Fatty Infiltration
- Trial name
- NCT07837583
- Volunteers
- 70 people
- Sponsor
- Assiut University