Clinical trials: Shift Work
Other Condition That May be a Focus of Clinical Attention
Humoral and Cellular Response in Shift Workers
The purpose of this study is to access whether shift workers (morning, afternoon or night) vaccinated against hepatitis A would have some humoral and cellular response impairment.
- Trial name
- NCT01528280
- Testing
- Vaccination against hepatitis A, No Intervention
- Where
- 2 sites in Brazil
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Problem Gambling, Addiction Gambling
Work Organization and Gambling Addiction
Problem gambling (PG) is influenced by environmental, psychological, and socioeconomic factors, including impulsivity, depression, anxiety, and characteristics such as marital status, age, and educational level.
- Trial name
- OTAJ (NCT07455981)
- Testing
- Completion of an online survey lasting approximately 25 minutes
- Where
- France
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Type 2 Diabetes, Shift-work Disorder
Effects of an Evening PROtein PrEload on Metabolic Health in Night ShIfT Workers (PROPENSITy)
This study will compare the effects of a whey protein supplement or a placebo consumed before the evening meal on health outcomes in night shift workers.
- Trial name
- PROPENSITy (NCT04869098)
- Testing
- whey protein
- Where
- Australia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Adelaide
Psychological Wellness
Impact of Exercise Intervention on Well-being in Shift-working Acute Care Nurses
This is a randomized, wait-list control pilot study to analyze the impact of a 12-week exercise training intervention on post-traumatic growth and whole-person well-being (mental health, physical health, spiritual well-being…
- Trial name
- WELL_NURSE (NCT05966805)
- Testing
- Exercise training group, Wait-List Control Group
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- AdventHealth
Work-Related Condition
Working Shift Organization, Caregivers' Satisfaction and Quality of Life at Work, and Performance.
This is a prospective, non-randomized, multicenter, observational national study, involving centers with different working shift organizations.
- Trial name
- IOTA-REA (NCT03875521)
- Where
- France
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Obesity & Overweight, Circadian Rhythm Disorders
Effects of Akkermansia Muciniphila and Berberine Supplementation on Insulin Sensitivity in Night-shift Workers
Night shift work is associated with an increased risk of obesity, insulin resistance, and cardiometabolic disorders, largely due to circadian misalignment, disrupted sleep, and altered eating patterns.
- Conditions
- Obesity & Overweight, Circadian Rhythm Disorders, Gut Microbiota Modulation, Prediabetes (Insulin Resistance, Impaired Glucose Tolerance)
- Trial name
- Shift2Health (NCT07440147)
- Testing
- Verum (A)
- Where
- Austria
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- FH Joanneum Gesellschaft mbH
Healthy Volunteers (HV)
Effects of a Sleep Education Program on the Health Status of Healthcare Workers Working 12-hour Alternating Day-night Shifts
In a context of seeking a better balance between personal and professional life and labor shortages, the use of 12-hour alternating day-night shifts has become more common in work organizations, particularly in healthcare…
- Trial name
- SLEEPMORE (NCT07326579)
- Testing
- Sleep educational
- Where
- 3 sites in France
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Shift-work Disorder
Impact of Night Shift Work on Dietary Habits Among Intensive Care and Emergency Healthcare Workers (NUTRINIGHT)
Night shift work is an essential component of healthcare systems, particularly in intensive care units and emergency departments, where continuous patient monitoring and rapid clinical decision-making are required.
- Trial name
- NCT07394283
- Testing
- Healthcare Night Shift Workers
- Where
- France
- Volunteers
- 245 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Caffeine, Sleep Deprivation
Real-Time Caffeine Optimization During Total Sleep Deprivation
Sleep deprivation (SD) has a powerful degrading effect on cognitive performance, particularly psychomotor vigilance (PV) and reaction time. Caffeine is well known to be an effective countermeasure to the effects of SD.
- Conditions
- Caffeine, Sleep Deprivation, Shift-Work Related Sleep Disturbance
- Trial name
- NCT04399083
- Testing
- Caffeine
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Impaired Driving, Sleep Driving
Objective Assessment of the Effects of Shift Work on Drowsiness and Driving Impairment in Hospital Staff
The purpose of this protocol is to assess the risk of drowsy driving amongst shift workers using objective measures of drowsiness and driving performance in an instrumented research vehicle.
- Trial name
- NCT01672489
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Sleep Disorder, Shift-Work
Examination of the Effectiveness of Suvorexant in Improving Daytime Sleep in Shift Workers
The purpose of this study is to test the hypothesis that ingestion of the wake-inhibiting drug suvorexant 30 minutes prior to daytime sleep initiation in individuals working overnight shifts will significantly improve both…
- Trial name
- NCT02491788
- Testing
- Suvorexant
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- VA Palo Alto Health Care System
Cognitive Performance, Sleep Quality
The Effect of Caffeinated Chewing Gum on Cognitive Performance in Night-shift Emergency Physicians
This study aimed to examine the impact of caffeinated chewing gum on the cognitive performance of night-shift emergency physicians in a partially sleep-deprived state.
- Trial name
- NCT06693505
- Testing
- caffeinated chewing gum
- Where
- Taiwan
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Sleep Disorders, Circadian Rhythm
Evaluation of the Effects of Pharmaton Tablets on Mental Performance and Physical Fatigue in Nurses Working Night Shift
The general aim of this study is to assess the effects of Pharmaton® Caplets on mental performance and physical fatigue in nurses and nursing auxiliaries working night shifts
- Trial name
- NCT02199847
- Testing
- Pharmaton® Caplets
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Breast Cancer, Prostate Cancer
Methylselenocysteine Effects on Circadian Rhythm
The primary objective of this study is to determine if vitamin supplementation with a naturally occurring dietary amino acid called organic selenium (i.e., methylselenocysteine) can restore disruption of circadian rhythm in shift…
- Trial name
- NCT01611038
- Testing
- Methylselenocysteine
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Shift Work Type Circadian Rhythm Sleep Disorder
The Influence of Nocturnal Food Intake in Eating Behavior of Night Workers
This study aimed to verify the influence of night work and food intake during the night shift on the eating behavior of fixed night workers the next day.
- Trial name
- NCT03800732
- Testing
- With Meal during night work, Without Meal during night work, Sleep night
- Where
- Brazil
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Federal University of Uberlandia
Shift Work Schedule
The Metabolic and Circadian Effects of Shift Work
In an exploratory observational pilot study, the investigators will focus on the effects of short-term circadian misalignment induced by shift work on multidimensional measurements including glucose excursion, metabolic health…
- Trial name
- OPTI-SHIFT (NCT05177965)
- Testing
- Exposure to shift work
- Where
- Switzerland
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Tinh-Hai Collet, MD
Chronodisruption, Shift Work Disorder
Impact of Shift Work on Glucose and Lipid Metabolism of Hospital Workers
The aim of the study is to evaluate circadian glucose, activity and dietary rhythms, as well as metabolic and cardiovascular risk associated with night shift work, sleep quality and well-being in a cohort of hospital staff…
- Conditions
- Chronodisruption, Shift Work Disorder, Glucose and Lipid Metabolism
- Trial name
- METASHIFT (NCT07426211)
- Where
- 2 sites in Germany
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Olga Ramich (formerly Pivovarova)
Dysbiosis
Analysis of Microbiota Variations in Industry Workers Working Different Shifts and Impact of a Nutritional Intervention
Shift workers are a growing population. It is well established that these workers face an increased risk of developing chronic diseases, but the underlying mechanisms remain debated.
- Trial name
- NCT04918537
- Testing
- Walnuts
- Where
- Switzerland
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Sophie Bucher Della Torre
Infectious Diseases, Healthy Subjects
Effect of the Consumption of a Fermented Milk on Common Infections in Shift-workers
This single-center, randomized, double-blind and controlled study aims to examine the effect of a fermented dairy product containing the probiotic Lactobacillus casei DN-114 001 (Actimel® = tested product) on the incidence of…
- Conditions
- Infectious Diseases, Healthy Subjects, Respiratory Tract Infections, Sore Throat
- Trial name
- NCT01033799
- Testing
- Fermented dairy product containing the probiotic Lactobacillus casei DN-114 001 (Actimel®), Non fermented dairy product (control)
- Where
- Germany
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Danone Global Research & Innovation Center
Sleep, Mood
Tryptophan Supplementation to Improve Night Shift Workers' Health
This randomized cross-over double-blinded trial aims to investigate the health effect of oral l-tryptophan supplementation on workers who rotate night shift work, and to examine the influences of different frequencies and timings…
- Conditions
- Sleep, Mood, Burnout, Melatonin Deficiency
- Trial name
- NCT04505800
- Testing
- Tryptophan supplement, Maltose
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University