Clinical trials: Shift-work Disorder
Skin Cancer
DNA Repair Activity in the Skin of Day and Night Shift Workers
The purpose of this study is to test how the skin of night shift workers responds to artificial sunlight (ultraviolet B radiation; UVB) at two different times of the day in comparison to normal day shift workers.
- Trial name
- NCT04122456
- Testing
- Ultraviolet B Radiation, No Ultraviolet B Radiation
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Wright State University
Musculoskeletal Pain, Cognitive Change
Health, Wellbeing and Performance in Law Enforcement Workers
This study aims to assess current health and fitness of law enforcement workers in various roles, and to evaluate the impact of an exercise intervention on markers on physical and mental wellbeing in this population.
- Conditions
- Musculoskeletal Pain, Cognitive Change, Occupational Stress, Inflammation
- Trial name
- NCT04204486
- Testing
- Exercise
- Where
- United Kingdom
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University College, London
Inflammation, Sleep Deprivation
Circadian Rhythm Disruption Effects on Smoke Inhalation
Particulate matter exposure during smoke inhalation provokes inflammatory immune responses in people exposed to burning biomass including fire fighters and civilians.
- Conditions
- Inflammation, Sleep Deprivation, Circadian Rhythm Sleep Disorder, Shift Work Type, Smoke Inhalation
- Trial name
- NCT04955431
- Testing
- Sleep Restriction, Normal Sleep
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Montana
Sleep
Extended Work Schedules, Sleep Loss and Health
This study aims to determine whether abnormal bodily rhythms contribute to elevate the risk of diabetes, independently of the amount of sleep loss.
- Trial name
- EW and EWD (NCT00989534)
- Testing
- Fixed restricted bedtimes, Sleep restriction with circadian misalignment
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Shift-Work Sleep Disorder, Insomnia
Fire Fighter Fatigue Management Program: Operation Fight Fatigue
Firefighters frequently work extended duration shifts and long work weeks which have adverse effects on alertness, health, safety and performance.
- Conditions
- Shift-Work Sleep Disorder, Insomnia, Restless Leg Syndrome, Obstructive Sleep Apnea
- Trial name
- NCT01672502
- Testing
- Sleep health education provided via a web-based program, Sleep disorder detection and treatment, Optimization of Sleep in Fire Station
- Where
- United States
- Volunteers
- 620 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Biomarkers of Stress in Emergency Physicians
Comparison of Biomarkers of Stress in Emergency Physicians Working a 24-hour Shift or a 14-hour Night Shift - the JOBSTRESS Randomized Trial
A stressful state can lead to symptoms of mental exhaustion, physical fatigue, medical errors, and also increase coronary heart disease. Emergency physicians subjectively complain of stress related to changes in work shifts.
- Trial name
- JOBSTRESS (NCT01874704)
- Testing
- Comparison of biomarkers of stress
- Where
- France
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Shift-Work Related Sleep Disturbance, Inflammation
Markers of Inflammation and of the Pro-thrombotic State in Hospital Shift and Day Workers
The goal of this observational study is to learn if acutely and/or chronically altered sleep induces inflammation and/or a pro-thrombotic state (a tendency to form clots) in hospital workers who either work in shifts or are…
- Conditions
- Shift-Work Related Sleep Disturbance, Inflammation, Hemostatic Disorder, Sleep Disorder
- Trial name
- IPNO (NCT05775731)
- Testing
- Tests for markers of inflammation and activated hemostasis
- Where
- Italy
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Centro Cardiologico Monzino
Lifestyle, Healthy, Sleepiness
Lifestyle Coaching for Fatigue Mitigation in Emergency Medicine Residents
The purpose of this study is to determine whether personalized lifestyle coaching minimizes the negative impact of circadian disruption on performance and recovery in emergency medicine physician trainees during night shifts.
- Conditions
- Lifestyle, Healthy, Sleepiness, Alertness, Shift-Work Related Sleep Disturbance
- Trial name
- NCT06015646
- Testing
- Personalized lifestyle coaching and educational handout, Handout
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Stanford University
Shift-work Disorder
EMS Providers' Health Initiative Study
This study aims to explore dietary factors that influence glycemic control in night shift EMS providers and to test the feasibility of a dietary intervention among these providers.
- Trial name
- NCT05153759
- Testing
- Meal service
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Circadian Rhythm Sleep Disorder
Effects of Chronobiology-guided Lifestyle Interventions on Insomnia Severity, Cognitive Performance, and Sleepiness
Poor sleep is closely related to circadian misalignment; shift workers often experience shift work disorder characterized by excessive sleepiness and recurrent shift work schedules-associated insomnia.
- Trial name
- NCT05569603
- Testing
- Chronobiology-guided lifestyle interventions
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Shift-Work Related Sleep Disturbance, Metabolic Syndrome
Health Effect of Canola Oil Consumption in Shift Workers
Shift work is associated with a higher risk of the development of cardiometabolic syndrome (CMtS) than in people working only during the day.
- Conditions
- Shift-Work Related Sleep Disturbance, Metabolic Syndrome, Diet Modification, Work-Related Condition
- Trial name
- NCT03977558
- Testing
- Intervention group, Control group
- Where
- Poland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Poznan University of Life Sciences
Sleep, Sleep Disturbance
Tech4Rest Trial With Team Truck Drivers
The current project is a safety and health intervention focused on sleep and fatigue among truck driver teams (pairs), where one driver sleeps in a moving vehicle while the other partner drives.
- Conditions
- Sleep, Sleep Disturbance, Sleep Disorder, Shift Work, Health Knowledge, Attitudes, Practice
- Trial name
- Tech4Rest (NCT03108599)
- Testing
- Enhanced Cab, Fit4Sleep
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Shift-Work Sleep Disorder
Light Treatment to Shift-working Nurses
This project examines 1) the effects of appropriately timed bright light on adaptation (in terms of sleep and sleepiness) to three consecutive night shifts; and 2) the effects of such bright light on re-adaptation (in terms of…
- Trial name
- NCT02978053
- Testing
- Bright light, Red light
- Where
- Norway
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Bergen
Chronic Insomnia, Sleep Deprivation
Evaluating the Efficacy and Safety of PROSOMNIA Sleep Therapy™ in Patients With Sleep Deprivation and Chronic Insomnia
This clinical trial aims to evaluate the safety and efficacy of PROSOMNIA Sleep Therapy (PSTx) for individuals suffering from chronic insomnia, sleep deprivation, and REM sleep disorders.
- Conditions
- Chronic Insomnia, Sleep Deprivation, REM Behavior Disorder, REM Sleep Behavior Disorder
- Trial name
- PSHW (NCT06644573)
- Testing
- PROSOMNIA Sleep Therapy™ (PSTx), Anesthesia-Induced Sleep Therapy, Diprivan (propofol), Astra-Zeneca
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Nyree Penn
Osteoporosis, Circadian Rhythm Sleep Disorder, Shift Work Type
Skeletal Response to Simulated Night Shift
This small intervention study will determine if simulated short-term night shift work (NSW) negatively alters bone metabolism. The specific aim of the study is to determine if NSW acutely uncouples bone turnover markers (BTMs)…
- Trial name
- SPOTLIGHT (NCT05074277)
- Testing
- Simulated short term night shift work schedule
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Shift-Work Sleep Disorder
The Effects of Lemborexant on the Ability to Sleep During Daytime
This study aim to evaluate whether a dose of 5 mg of lemborexant, as compared to a placebo, may improve daytime recovery sleep, without producing lingering sleepiness during wakefulness, using a 3-day simulated night shift…
- Trial name
- NCT06231641
- Testing
- Lemborexant 5 MG [Dayvigo]
- Where
- Canada
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal
Problem Gambling, Addiction Gambling
Work Organization and Gambling Addiction
Problem gambling (PG) is influenced by environmental, psychological, and socioeconomic factors, including impulsivity, depression, anxiety, and characteristics such as marital status, age, and educational level.
- Trial name
- OTAJ (NCT07455981)
- Testing
- Completion of an online survey lasting approximately 25 minutes
- Where
- France
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Night Work
Apples in Night Shift
Background: Emergency doctors face a highly stressful work environment during night shifts. Long-term night shift work can lead to sleep deprivation, fatigue accumulation, and disruption of the biological clock, which may affect…
- Trial name
- NCT06714422
- Testing
- apple group, no apple group
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Type 2 Diabetes, Shift-work Disorder
Effects of an Evening PROtein PrEload on Metabolic Health in Night ShIfT Workers (PROPENSITy)
This study will compare the effects of a whey protein supplement or a placebo consumed before the evening meal on health outcomes in night shift workers.
- Trial name
- PROPENSITy (NCT04869098)
- Testing
- whey protein
- Where
- Australia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Adelaide
Impaired Driving, Sleep Driving
Objective Assessment of the Effects of Shift Work on Drowsiness and Driving Impairment in Hospital Staff
The purpose of this protocol is to assess the risk of drowsy driving amongst shift workers using objective measures of drowsiness and driving performance in an instrumented research vehicle.
- Trial name
- NCT01672489
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital