Clinical trials: Shift-work Disorder
Work Stress, Sleep Disturbance
The Use of Worktime Planning Tools in the Finnish Public Sector. A Quasi-experimental Study (PLANTOOLS)
This study aims to investigate whether use of interactive worktime planning tools that support work-time control (possibilities to influence individual shift rosters, i.e., participatory rostering) and guide for health-supporting…
- Trial name
- PLANTOOLS (NCT02775331)
- Testing
- Shift planning with self-rostering and shift ergonomics, Shift planning with shift ergonomics
- Volunteers
- 9,000 people, healthy volunteers welcome
- Sponsor
- Finnish Institute of Occupational Health
Healthcare Workers, Stress Level
Effects of VR-based Respiratory Training on Motor Reaction Time and Correctness, Stress Levels, Attention, Motor Skills, Postural Stability and Sleep Quality in Shift Healthcare Workers
This study investigates the effects of virtual reality (VR)-based respiratory training on various physiological and cognitive functions in shift-working healthcare professionals, including paramedics and nurses.
- Conditions
- Healthcare Workers, Stress Level, Emergency Department, Shift Work Sleep Disorder
- Trial name
- NCT06926257
- Testing
- Experimental group (B) - breathing training using VR, Experimental group (C) - breathing training using relaxation music
- Where
- Poland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Shift Work Sleep Disorder, Shift Work Type Circadian Rhythm Sleep Disorder
Recovery and Early Sleep Tracking Using the SuperPatch REM Patch
A Phase 1 Feasibility Study of the SuperPatch REM Patch for Post-Night-Shift Sleep Recovery in NHS Doctors
- Conditions
- Shift Work Sleep Disorder, Shift Work Type Circadian Rhythm Sleep Disorder, Shift Work Sleep Disorders
- Trial name
- REST (NCT07785960)
- Testing
- SuperPatch REM Patch
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- SuperPatch Limited LLC
Biomarkers of Stress in Emergency Physicians
Comparison of Biomarkers of Stress in Emergency Physicians Working a 24-hour Shift or a 14-hour Night Shift - the JOBSTRESS Randomized Trial
A stressful state can lead to symptoms of mental exhaustion, physical fatigue, medical errors, and also increase coronary heart disease. Emergency physicians subjectively complain of stress related to changes in work shifts.
- Trial name
- JOBSTRESS (NCT01874704)
- Testing
- Comparison of biomarkers of stress
- Where
- France
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Sleep Quality
Filtered Eyewear to Prevent Light-induced Melatonin Suppression - Aim 1
The aim of this study is to determine the relative effectiveness of monocular and binocular light exposures, with and without selective blue-blocking filtering, on nocturnal melatonin suppression, subjective sleepiness, and…
- Trial name
- NCT06310135
- Testing
- Filtered Eyewear, Unfiltered Eyewear, No Filters
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Inflammation, Sleep Deprivation
Circadian Rhythm Disruption Effects on Smoke Inhalation
Particulate matter exposure during smoke inhalation provokes inflammatory immune responses in people exposed to burning biomass including fire fighters and civilians.
- Conditions
- Inflammation, Sleep Deprivation, Circadian Rhythm Sleep Disorder, Shift Work Type, Smoke Inhalation
- Trial name
- NCT04955431
- Testing
- Sleep Restriction, Normal Sleep
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Montana
Skin Cancer
DNA Repair Activity in the Skin of Day and Night Shift Workers
The purpose of this study is to test how the skin of night shift workers responds to artificial sunlight (ultraviolet B radiation; UVB) at two different times of the day in comparison to normal day shift workers.
- Trial name
- NCT04122456
- Testing
- Ultraviolet B Radiation, No Ultraviolet B Radiation
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Wright State University
Other Condition That May be a Focus of Clinical Attention
Humoral and Cellular Response in Shift Workers
The purpose of this study is to access whether shift workers (morning, afternoon or night) vaccinated against hepatitis A would have some humoral and cellular response impairment.
- Trial name
- NCT01528280
- Testing
- Vaccination against hepatitis A, No Intervention
- Where
- 2 sites in Brazil
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Problem Gambling, Addiction Gambling
Work Organization and Gambling Addiction
Problem gambling (PG) is influenced by environmental, psychological, and socioeconomic factors, including impulsivity, depression, anxiety, and characteristics such as marital status, age, and educational level.
- Trial name
- OTAJ (NCT07455981)
- Testing
- Completion of an online survey lasting approximately 25 minutes
- Where
- France
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Type 2 Diabetes, Shift-work Disorder
Effects of an Evening PROtein PrEload on Metabolic Health in Night ShIfT Workers (PROPENSITy)
This study will compare the effects of a whey protein supplement or a placebo consumed before the evening meal on health outcomes in night shift workers.
- Trial name
- PROPENSITy (NCT04869098)
- Testing
- whey protein
- Where
- Australia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Adelaide
Work-Related Condition
Working Shift Organization, Caregivers' Satisfaction and Quality of Life at Work, and Performance.
This is a prospective, non-randomized, multicenter, observational national study, involving centers with different working shift organizations.
- Trial name
- IOTA-REA (NCT03875521)
- Where
- France
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Obesity & Overweight, Circadian Rhythm Disorders
Effects of Akkermansia Muciniphila and Berberine Supplementation on Insulin Sensitivity in Night-shift Workers
Night shift work is associated with an increased risk of obesity, insulin resistance, and cardiometabolic disorders, largely due to circadian misalignment, disrupted sleep, and altered eating patterns.
- Conditions
- Obesity & Overweight, Circadian Rhythm Disorders, Gut Microbiota Modulation, Prediabetes (Insulin Resistance, Impaired Glucose Tolerance)
- Trial name
- Shift2Health (NCT07440147)
- Testing
- Verum (A)
- Where
- Austria
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- FH Joanneum Gesellschaft mbH
Shift-work Disorder
Impact of Night Shift Work on Dietary Habits Among Intensive Care and Emergency Healthcare Workers (NUTRINIGHT)
Night shift work is an essential component of healthcare systems, particularly in intensive care units and emergency departments, where continuous patient monitoring and rapid clinical decision-making are required.
- Trial name
- NCT07394283
- Testing
- Healthcare Night Shift Workers
- Where
- France
- Volunteers
- 245 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Caffeine, Sleep Deprivation
Real-Time Caffeine Optimization During Total Sleep Deprivation
Sleep deprivation (SD) has a powerful degrading effect on cognitive performance, particularly psychomotor vigilance (PV) and reaction time. Caffeine is well known to be an effective countermeasure to the effects of SD.
- Conditions
- Caffeine, Sleep Deprivation, Shift-Work Related Sleep Disturbance
- Trial name
- NCT04399083
- Testing
- Caffeine
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Impaired Driving, Sleep Driving
Objective Assessment of the Effects of Shift Work on Drowsiness and Driving Impairment in Hospital Staff
The purpose of this protocol is to assess the risk of drowsy driving amongst shift workers using objective measures of drowsiness and driving performance in an instrumented research vehicle.
- Trial name
- NCT01672489
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Sleep Disorder, Shift-Work
Examination of the Effectiveness of Suvorexant in Improving Daytime Sleep in Shift Workers
The purpose of this study is to test the hypothesis that ingestion of the wake-inhibiting drug suvorexant 30 minutes prior to daytime sleep initiation in individuals working overnight shifts will significantly improve both…
- Trial name
- NCT02491788
- Testing
- Suvorexant
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- VA Palo Alto Health Care System
Cognitive Performance, Sleep Quality
The Effect of Caffeinated Chewing Gum on Cognitive Performance in Night-shift Emergency Physicians
This study aimed to examine the impact of caffeinated chewing gum on the cognitive performance of night-shift emergency physicians in a partially sleep-deprived state.
- Trial name
- NCT06693505
- Testing
- caffeinated chewing gum
- Where
- Taiwan
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Sleep Disorders, Circadian Rhythm
Evaluation of the Effects of Pharmaton Tablets on Mental Performance and Physical Fatigue in Nurses Working Night Shift
The general aim of this study is to assess the effects of Pharmaton® Caplets on mental performance and physical fatigue in nurses and nursing auxiliaries working night shifts
- Trial name
- NCT02199847
- Testing
- Pharmaton® Caplets
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Breast Cancer, Prostate Cancer
Methylselenocysteine Effects on Circadian Rhythm
The primary objective of this study is to determine if vitamin supplementation with a naturally occurring dietary amino acid called organic selenium (i.e., methylselenocysteine) can restore disruption of circadian rhythm in shift…
- Trial name
- NCT01611038
- Testing
- Methylselenocysteine
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Shift Work Type Circadian Rhythm Sleep Disorder
The Influence of Nocturnal Food Intake in Eating Behavior of Night Workers
This study aimed to verify the influence of night work and food intake during the night shift on the eating behavior of fixed night workers the next day.
- Trial name
- NCT03800732
- Testing
- With Meal during night work, Without Meal during night work, Sleep night
- Where
- Brazil
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Federal University of Uberlandia