Clinical trials: Shock
Systemic Inflammatory Response Syndrome
Evaluation of Corticosteroid in Systemic Inflammatory Response Syndrome
Cardiac surgery and cardiopulmonary bypass (CPB) initiate a whole-body systemic inflammatory response (SIRS) characterized by the activation of leukocytes, monocytes, and the complement cascade.
- Trial name
- NCT03876041
- Testing
- solumedrol, Dexamethasone phosphate
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Nasal Valve Incompetence, Alar Collapse
Measurement of Age and Sex Related Changes in Nasal Tip Support Using Digital Newton Meter
Background: It is predicted that the nasal tip support will decrease with aging due to weakening of cartilage and connective tissues. However, there is no consensus on the age at which this change began.
- Trial name
- NCT04017923
- Testing
- measurement of nasal tip support in different age groups.
- Where
- Turkey (Türkiye)
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Baskent University Ankara Hospital
Severe Sepsis With Septic Shock, Severe Sepsis Without Septic Shock
Long-term Cognitive and Cerebral Changes in Sepsis Survivors and Their Predictors
The main goals of this study are to provide a cognitive, neurological, brain morphological, and serological profile of sepsis survivors in order to make long-term prognosis of recovery and estimate the need for rehabilitation…
- Trial name
- BonSEP (NCT02339649)
- Testing
- Blood Sample, Neurocognitive Assessment, Resting State EEG
- Where
- 2 sites in Germany
- Volunteers
- 308 people, healthy volunteers welcome
- Sponsor
- German Center for Neurodegenerative Diseases (DZNE)
Sepsis, Septic Shock
Myeloid Bias in the Bone Marrow of Septic Patients and Its Correlation With Disease Severity and Prognosis: A Single-Center, Prospective Cohort Study
Sepsis remains a leading cause of critical illness worldwide, yet the underlying mechanisms driving its profound and persistent immune dysfunction are incompletely understood.
- Trial name
- NCT07667153
- Testing
- Bone marrow aspirate collection
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Lateral Epicondylitis, Extracorporeal Shock Wave Therapy
Effect of Extracorporeal Shock Wave Therapy (ESWT) and Phonophoresis Treatment in Patients With Lateral Epicondylitis
This study aimed to investigate the effects of Extracorporeal Shock Wave Therapy and phonophoresis treatment on pain, function, hand grip strength and tendon thickness in ultrasonography in patients with lateral epicondylitis.
- Conditions
- Lateral Epicondylitis, Extracorporeal Shock Wave Therapy, Phonophoresis
- Trial name
- NCT06603181
- Testing
- conventional treatment, phonophoresis, extracorporeal shock wave therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kirsehir Ahi Evran Universitesi
Burn Shock
Effect of Pre-emptive Intravenous Immunoglobulin (IVIG) on the Incidence of Septic Episodes in Pediatric Burn Patients
Effect of pre-emptive intravenous immunoglobulin administration on the incidence of septic episodes in pediatric burn patients: A randomized controlled study.
- Trial name
- NCT05134792
- Testing
- intravenous immunoglobulin
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Stroke, Spasticity
Efficacy of Shock Wave Therapy in Post-Stroke Muscle Spasticity Management
The goal of this clinical trial is to evaluate the efficacy and safety of shock wave therapy (SWT) in reducing muscle spasticity in patients who have suffered a stroke.
- Conditions
- Stroke, Spasticity, Post-stroke, Muscle Hypertonia
- Trial name
- SWT-PI (NCT06815328)
- Testing
- Shock Wave Therapy (SWT), Active Comparator - Conventional Therapy
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Oviedo
Mechanical Low Back Pain
Shock Wave Therapy Versus Mechanical Traction on Mechanical Low Back Pain
investigate the effect of shock wave therapy versus mechanical traction on mechanical low back pain.
- Trial name
- NCT05088031
- Testing
- shock waves therapy
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Merit University
Dengue
Evaluation of the Safety and Immune Response of Five Admixtures of a Tetravalent Dengue Virus Vaccine
Dengue viruses can cause dengue fever and other serious health conditions, primarily affecting people living in tropical regions of the world.
- Trial name
- NCT01072786
- Testing
- TetraVax-DV Vaccine-Admixture 1, TetraVax-DV Vaccine-Admixture 2, TetraVax-DV Vaccine-Admixture 3
- Where
- 4 sites in United States
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Dengue
Evaluating the Safety and Immune Response to Two Admixtures of a Tetravalent Dengue Virus Vaccine
Dengue viruses can cause dengue fever and other serious health conditions, primarily affecting people living in tropical regions of the world.
- Trial name
- NCT01436422
- Testing
- TetraVax-DV Vaccine - Admixture TV003, TetraVax-DV Vaccine - Admixture TV005
- Where
- 3 sites in United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Obstructive Sleep Apnea
Drug Induced Submental Ultrasound in Obstructive Sleep Apnea Patients
In this study, submental ultrasound during awake and simultaneous under Drug-induced sleep endoscopy is applied in the diagnostic workup of obstructive sleep apnea patients.
- Trial name
- NCT03285451
- Testing
- submental ultrasonography
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation
Hypoperfusion
Using Fluorescence Angiography to Detect Occult Shock
The purpose of this study is to determine if fluorescence angiography can detect occult shock (hypoperfusion).
- Trial name
- NCT02846727
- Testing
- skin perfusion image
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Yale University
Sepsis, Septic Shock
Central Venous Catheter Colonisation Among Critically Ill Patients in Intensive Care Units
Background: Central Venous catheter insertion technique and indwelling time are major risk factors for CVC colonisation. Colonisation occurs through microbial migration and biofilm formation along the catheter insertion tract.
- Conditions
- Sepsis, Septic Shock, Post-cardiac Surgery, Post-Cardiorespiratory Arrest Coma
- Trial name
- NCT03270774
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Makerere University
Shockwave Lithotripsy, Pain
The Effect of Virtual Reality Application on Pain and Anxiety Level in Stone Crushing With Shock Waves: A Randomized Controlled Trial
This research was planned as a randomized controlled experimental study in order to evaluate the effect of virtual reality application on pain and anxiety caused by the procedure during stone crushing process (ESWL) with shock…
- Conditions
- Shockwave Lithotripsy, Pain, Anxiety, Virtual Reality
- Trial name
- NCT05645445
- Testing
- virtual reality
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Duzce University
Cardiovascular Risk Factor, Metabolic Disease
Effects of Shockwave Therapy Versus Radiofrequency
The main objective of this study is to compare the effect of 6 sessions of shock wave therapy versus radiofrequency followed by a protocol of moderate aerobic exercise, in the reduction of adiposity and abdominal flaccidity, in…
- Conditions
- Cardiovascular Risk Factor, Metabolic Disease, Photoaging
- Trial name
- NCT04282057
- Testing
- Radiofrequency, Aerobic exercise, Shock wave therapy
- Where
- Portugal
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Escola Superior de Tecnologia da Saúde do Porto
Neck Pain, Extracorporeal Shock Waves Therapy
Effect of Extracorporeal Shockwave Therapy Before Postural Correction Exercise in Adults With Forward Head Posture
Currently, as digital leisure activities increase, more time is spent at home. According to these social trends, it is necessary to establish a program that can safely and effectively perform exercise at home.Therefore, this…
- Conditions
- Neck Pain, Extracorporeal Shock Waves Therapy, Exercise Program
- Trial name
- NCT05855772
- Testing
- Extracorporeal shock waves, Posture Correction Exercise Program
- Where
- South Korea
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Sahmyook University
Sepsis, Severe Sepsis
Subpopulation-Specific Sepsis Identification Using Machine Learning
The focus of this study will be to conduct a prospective, randomized controlled trial (RCT) at Cape Regional Medical Center (CRMC), Oroville Hospital (OH), and UCSF Medical Center (UCSF) in which a subpopulation-optimized…
- Conditions
- Sepsis, Severe Sepsis, Septic Shock
- Trial name
- NCT03644940
- Testing
- CustomSight
- Volunteers
- healthy volunteers welcome
- Sponsor
- Dascena
Anxiety Disorders
Expectation of Unpleasant Events in Anxiety Disorders
Fear and anxiety are normal responses to a threat. However, anxiety is considered abnormal when the response to the threat is excessive or inappropriate.
- Trial name
- NCT00055224
- Testing
- Threat of shock
- Where
- United States
- Volunteers
- 921 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Multi-organ Failure After Severe Trauma
Metabolic Reprogramming in Renal Tubular Cells in Acute Kidney Injury Following Severe Trauma
Severe trauma remains the leading cause of death in people under 50, and is associated with high morbidity, including severe disability, with a substantial socio-economic impact.
- Trial name
- METAKIT (NCT06167512)
- Where
- 2 sites in France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Alveolar Ridge Collapse
Volumetric Analysis of Alveolar Ridge Contour Using Sub-epithelial Connective Tissue Graft
This study will monitor the effect of soft tissue augmentation using sub-epithelial connective tissue graft buccal to extraction sockets in anterior maxilla in thin dento-alveolar phenotype; and will evaluate whether it will…
- Trial name
- NCT04482127
- Testing
- SubEpithelial connective graft
- Where
- Egypt
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Cairo University