Clinical trials: Short-Sighted
Full Spectrum
A Self-controlled Study of the Effect of Partial Spectral Absence of Visible Light on the Pupil
Previous studies have shown that the spectrum of light influences myopia. LED lights with a partially absent light spectrum increase the risk of myopia progression compared to LEDs with a full spectrum, potentially mediated by…
- Trial name
- NCT06501131
- Testing
- full-spectrum light exposure, specific spectrum absence light exposure
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Myopia
Fitting Evaluation of Hydrogel and Silicone Hydrogel Sphere Design Contact Lenses
The aim of this non-dispensing fitting study is to evaluate the short term lens fit, vision performance of three monthly replacement sphere lenses.
- Trial name
- NCT03098745
- Testing
- Omafilcon A, Somofilcon A, Omafilcon A - Proclear (PC)
- Where
- Mexico
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopic LASIK Candidates With Spherical Equivalent up to - 10 Diopters
Thin-Flap Laser in Situ Keratomileusis Associated Dry Eye
Laser in situ keratomileusis (LASIK) eye surgery continues to be the most common refractive procedure used to correct different forms of ametropia.
- Trial name
- NCT04831177
- Testing
- Laser in situ keratomileusis
- Where
- Egypt
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Assiut University
Choroidal Neovascular Membrane In Wet Age Related Macular Degeneration And In Pathological Myopia
Optical Coherence Tomography Angiography Criteria Of The Choroidal Neovascular Membrane In Wet Age Related Macular Degeneration And In Pathological Myopia (Comparative Study).
This study aims to compare choroidal neo-vascular membrane criteria in cases of age-related macular degeneration and cases of pathological myopia.
- Trial name
- NCT05562336
- Testing
- Optical coherence tomography angiography
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Sohag University
Myopia
Corneal WFG Versus AF Trans PRK in Myopic Patients With High Corneal HOA
compare the efficacy, safety and predictability of corneal wavefront guided (WFG) and aberration free ablation in single-step transepithelial photorefractive keratectomy (TransPRK) in myopic patients with high pre-existing…
- Trial name
- NCT03786861
- Testing
- corneal WFG group, aberration free group
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Myopia, Astigmatism
Wavefront-guided Photorefractive Keratectomy (PRK) Versus Wavefront-guided Lasik for Myopia
A prospective comparison of eyes undergoing wavefront-guided LASIK in one eye and wavefront-guided PRK in their fellow eye for myopia.
- Trial name
- NCT01140594
- Testing
- Photorefractive keratectomy, Laser in-situ keratomileusis
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Stanford University
Myopia, Hyperopia
Evaluation of Effectiveness of Correcting Refractive Error With Ready-made Spectacles
This research project will compare two methods of correcting refractive error (long or short-sightedness) with spectacle lenses.
- Conditions
- Myopia, Hyperopia, Astigmatism
- Trial name
- RECS (NCT00657670)
- Testing
- Ready-made spectacles, Spectacles
- Where
- 2 sites in China, India
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Myopia, Prevention and Control
Effectiveness of Digital Defocus Vision Training With Low-Concentration Atropine on the Prevention and Control of Myopia in Children: A Clinical Study
Based on existing theories of myopia development and progression, our preliminary work has leveraged the features of virtual reality (VR) technology to digitally simulate myopic defocus signals through image-based emulation.
- Trial name
- NCT07724210
- Testing
- For the experimental group,Virtual reality-based digital defocus training combined with 0.02% atropine eye drops, For the control group, one drop of 0.02% atropine eye drops was instilled into each eye at bedtime daily, combined with full-time wear of fully corrected multi-zone positive optical defocus (DIMS) spe
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Beijing Tongren Hospital
Myopia
Myopia Control Using Optimized Optical Defocus RCTs
The aims of the study is to evaluate whether the DISC3.5 Plus contact lens will slow myopia progression and axial length growth in myopic children as compared with single vision soft contact lenses.
- Trial name
- NCT03681366
- Testing
- DISC3.5 plus
- Where
- China
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Myopia
Dual Focus Soft Contact Lens Wear Cessation Study
The purpose of this study is to investigate the effect of ceasing treatment with dual focus soft contact lenses.
- Trial name
- NCT05779072
- Testing
- Single Vision Soft Contact Lens
- Where
- 4 sites in Canada, Portugal and 2 more
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia, Maculopathy
Optical Coherence Tomography Imaging of the Posterior Segment in High Myopia.
The prevalence of myopia in East Asia and Singapore in particular is amongst the highest in the world, with estimates ranging from 30-70% of the general population. Up to 30% of these are high myopes.
- Conditions
- Myopia, Maculopathy, Glaucoma
- Trial name
- NCT00347451
- Where
- Singapore
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Singapore National Eye Centre
Near Vision, Refractive Error Correction
Clinical Outcomes of the Use of a Femtosecond Laser Treatment in a Patient With Implanted Monofocal IOLs
This study aims to assess the safety and efficacy of evaluating near vision or refractive error in eyes implanted with a mono focal intraocular lens (IOL) using a low-energy femtosecond laser.
- Trial name
- NCT07447622
- Testing
- Device
- Where
- Czechia
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Perfect Lens, LLC
Myopia
Post-market Follow Up Study on Paragon CRT® 100 (Paflufocon D)
The main objective of this post market clinical study is to evaluate the effectiveness and safety of the Paragon CRT®100 Contact Lens.
- Trial name
- NCT04187599
- Testing
- Paragon CRT®100 Contact Lens
- Where
- 4 sites in China
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- CooperVision International Limited (CVIL)
Myopia
Myopic Control for High Myopes Using Orthokeratology
The purpose of this study is to evaluate and compare the eyeball elongation in high myopic children using partial correction orthokeratology and single-vision spectacles.
- Trial name
- HM-PRO (NCT00977236)
- Testing
- Orthokeratology lenses, Single-vision spectacle lenses
- Where
- China
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Myopia, Myopia; Refractive Error
Peripheral Relative Refractive Power of Orthokeratology Lenses
Orthokeratology (OK) has been demonstrated to be an effective intervention for slowing axial elongation in children with myopia.
- Trial name
- NCT07294404
- Testing
- orthokeratology
- Where
- China
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Myopia
A Study to Evaluate the Performance of Two Designs of Soft Toric Lenses
The objective of the study is to evaluate the product performance of the Bausch + Lomb toric investigational contact lenses compared to the currently marketed PureVision toric contact lenses.
- Trial name
- NCT01309867
- Testing
- Investigational Toric Lens, PureVision Toric Lens
- Where
- United States
- Volunteers
- 302 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Hyperopia, Myopia
Clinical Study of Visibility Tinted Clariti Contact Lens
The purpose of this study was to investigate the safety and efficacy of the Sauflon Clariti Monthly silicone hydrogel contact lenses with handling tint (Sauflon Pharmaceuticals Limited) by comparison with Air Optix Aqua silicone…
- Trial name
- NCT01996787
- Testing
- Air Optix Aqua, Clariti with Handling Tint
- Where
- United Kingdom
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Sauflon Pharmaceuticals Ltd
Myopia
Contact Lenses and Myopia
The objective of this study is to determine if multifocal contact lenses affect accommodation and/or binocular vision when worn by pediatric patients.
- Trial name
- CLAM (NCT02180347)
- Testing
- Contact lenses
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- State University of New York College of Optometry
Myopia
Evaluation of Wear Experience With One Week Reusable Contact Lenses in Habitual Two Week Reusable Lens Wearers
This open-label study is of current Acuvue® Oasys® wearers (2 - week replacement, reusable lenses) who are satisfied with their current lenses.
- Trial name
- NCT06382064
- Testing
- Biweekly replacement contact lenses, One week replacement contact lenses
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Myopia
AI-Stratified Myopia Control for Children in Remote Areas
This cluster-randomized controlled trial aims to evaluate the effectiveness and cost-effectiveness of an artificial intelligence-based, risk-stratified, tiered intervention model for childhood myopia prevention and control in…
- Trial name
- NCT07825428
- Testing
- Routine Screening and Referral, AI-Guided Tiered Management
- Where
- 3 sites in China
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center