Clinical trials: Short-Sighted
Myopia, Astigmatism
Randomized, Prospective Comparison of the Outcome of Toric Implantable Contact Lens (TICL) and Q-LASIK for the Correction of Myopia With Astigmatism
The objective is to conduct a contralateral prospective clinical study to compare the safety, efficacy, and quality of vision of the STAAR Surgical Co.
- Trial name
- NCT01088568
- Testing
- the implantation of toric implantable collamer lens, customized laser-assisted in situ keratomileusis
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Wenzhou Medical University
Myopia
Investigation of Multi-Purpose Solution-Based Corneal Staining and Ocular Comfort
The primary objective of this study is to compare subjective ocular symptoms and corneal staining over time in a group of individuals who wear soft contact lenses on a daily wear basis, whilst they sequentially use two different…
- Trial name
- NCT00349843
- Testing
- Soft contact lens, Marketed soft lens multipurpose disinfection regimen
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Waterloo
Myopia
Evaluation of the Performance of Different Daily Disposable Lens Designs in Habitual Soft Contact Lens Wearers
The main objective of the study is to refit existing soft lens wearers with two different daily disposable contact lens types, Lens A and Lens B, to determine their performance after one week of wear.
- Trial name
- NCT04668989
- Testing
- stenfilcon A - (Test lens), kalifilcon A - (Control Lens)
- Where
- 4 sites in United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Juvenile Myopia, Myopia
Assessment of DOT Spectacles in Chinese Children
This is a randomized, controlled, evaluator-blinded, multicenter, two-arm parallel group clinical trial to evaluate the continued safety and efficacy of Diffusion Optics Technology (DOT) spectacle lenses by comparing to single…
- Trial name
- CATHAY (NCT05562622)
- Testing
- Novel spectacle lens design, Spectacle lenses
- Where
- 5 sites in China
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- SightGlass Vision, Inc.
Myopia
Lacritin and Heparanase Levels in Human Tears After Laser Refractive Surgery
The purpose of this study is to measure tear lacritin and heparanase levels before and following surgery using a minimal risk procedure to collect tears from patients undergoing PRK or LASIK.
- Trial name
- NCT01049724
- Testing
- Tear collection
- Where
- United States
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Fort Belvoir Community Hospital
Myopia, Myopia, Progressive
Can Distance Center and Near Center Multifocal Contact Lenses Control Myopia Progression in Children?
Myopia has been increasing in prevalence and severity throughout the world over the last 30 years. Increasing levels of myopia are associated with increased frequency and severity of various ocular pathologies.
- Trial name
- ADPADP (NCT03519490)
- Testing
- Hybrid Contact Lens
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Thomas A. Aller, OD
Myopia
The Response to Atropine Drops (RAD) Study
The purpose of this study is to examine the comfort of giving low concentration atropine eye drops.
- Trial name
- NCT05199597
- Testing
- 0.01% atropine, 0.05% atropine
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Accomodation, Biofeedback Training
Assessment of Accommodation Behavior in Children Under Myopia Control Treatment (Pilot Study)
This study will examine the accommodative behavior in children undergoing myopia control treatments. A subset of children showing reduced accommodation, known to occur in while wearing multifocal soft contact lenses (MFCL) from…
- Conditions
- Accomodation, Biofeedback Training, Myopia
- Trial name
- NCT04807361
- Testing
- Auditory biofeedback traing
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- State University of New York College of Optometry
Myopia
Myopia Progression After Ceasing Myopia Control Contact Lens Wear
This is a continuation study for subjects who were previously fit with test or control lenses; all will stop wearing their study lenses assigned in the previous study and will start to wear an FDA-approved marketed spherical soft…
- Trial name
- NCT01829230
- Testing
- 1 Day Acuvue Moist
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia, Progressive, Children, Only
Myopia Control With Orthokeratology Contact Lenses in Spain
The purpose of this prospective study is to assess the efficacy, safety and patient-reported outcomes of the Menicon Z Night orthokeratolgy contact lens for reducing myopia progression in children.
- Conditions
- Myopia, Progressive, Children, Only, Contact Lens Complication, Perception, Self
- Trial name
- MCOS (NCT04806763)
- Testing
- Menicon Z Night, Control
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Menicon Co., Ltd.
Aging
Heart Aging When Near Vision Difficulty Begins
Near vision deterioration during aging results from a decrease in accomodation amplitude (AA). Myocardial regeneration is limited, and cardiac aging is an independent risk factor for cardiovascular disease.
- Trial name
- NCT04362215
- Testing
- Subjective accomodation amplitude measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Kecioren Education and Training Hospital
Myopia
Evaluation of Two Daily Disposable Contact Lenses.
The objective of this clinical study is to evaluate the product performance of SofLens daily disposable contact lenses packaged in the investigational Test solution versus SofLens daily disposable contact lenses packaged in…
- Trial name
- NCT01300065
- Testing
- Experimental- Soflens, Marketed - Soflens
- Where
- United States
- Volunteers
- 441 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Posterior Chamber Phakic Intraocular Lens, Vault
Study on the Diagnostic Efficacy of ICL Selection and Prediction Depth Model Based on Eye Images
To evaluate the diagnostic efficacy of deep learning network model in implantable collamer lens selection and prediction in a multicenter cross-sectional study
- Conditions
- Posterior Chamber Phakic Intraocular Lens, Vault, Deep Neural Network, Myopia
- Trial name
- NCT06669728
- Testing
- AI diagnostic algorithm
- Where
- China
- Volunteers
- 326 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Nanchang University
Myopia, Astigmatism
Wavefront-guided PRK vs Wavefront-optimized PRK
The purpose of the study is to compare the results of PRKK surgery when using wavefront-guided excimer laser treatment compared to wavefront optimized excimer laser treatment in patients with nearsightedness with and without…
- Trial name
- NCT02091934
- Testing
- Wavefront-guided PRK, Wavefront-optimized PRK
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Stanford University
Myopia Progression
Factors Influencing Physiological Hyperopia in Children
The trend of myopia in children and its low age is a major social and public health problem in China. More seriously, retinopathy associated with high myopia has become the number one cause of irreversible blinding eye disease in…
- Trial name
- NCT06498947
- Testing
- This study was observational with no intervention.
- Where
- China
- Volunteers
- 1,006 people, healthy volunteers welcome
- Sponsor
- Beijing Tongren Hospital
Myopia, Hyperopia
Safety and Efficacy Study of Topography-Guided LASIK to Treat Myopia and Hyperopia
This purpose of this study is to evaluate the safety and effectiveness of a topography-based custom ablation treatment using the ALLEGRETTO WAVE® Eye-Q 400 Hz laser system for treating myopia and hyperopia.
- Trial name
- NCT01028378
- Testing
- T-CAT topography-guided LASIK treatment with the Allegretto Wave Eye-Q 400 Hz Excimer Laser
- Where
- 10 sites in United States
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- Clinical Research Consultants, Inc.
Myopia
Multi-Centre Clinical Evaluation of Two Reusable Soft Contact Lenses
The aim of this study is to compare the subjective performance of the comfilcon A contact lens against lotrafilcon B contact lens after 4 weeks of reusable lens wear.
- Trial name
- NCT02815735
- Testing
- comfilcon A, lotrafilcon B
- Where
- 9 sites in United Kingdom
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia
Delaying the Onset of Nearsightedness Until Treatment (DONUT) Clinical Trial
The aims of this clinical trial will test whether or not the onset of nearsightedness is delayed in a group of children randomized to nightly drops in 0.05% atropine in both eyes, in comparison to children who receiving nightly…
- Trial name
- DONUT (NCT07567040)
- Testing
- Atropine Sulfate 0.05% Oph Soln
- Where
- 13 sites in United States
- Volunteers
- 664 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Myopia
Identification of Genomic Loci Determining Susceptibility to the Development of High Myopia
Compelling evidence of genetic components in high myopia has been put forward by several studies. Twin cohorts, familial linkage studies and population studies has described at least 10 loci containing genes involved in the…
- Trial name
- ASSOMYP (NCT02583620)
- Testing
- blood sample
- Where
- 4 sites in France
- Volunteers
- 553 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Myopia Progression
Orthokeratology Lens Decentration with Two Designs of Corneal Refractive Therapy™ Lenses: a One-year Prospective Study
Background/Objectives: To examine the trend of treatment zone (TZ) decentration over 12 months of Orthokeratology (OK) wear using two corneal refractive therapy (CRT) lens designs: standard (STD) and dual axis (DA).
- Trial name
- NCT06726499
- Testing
- Spherical CRT, Toric CRT
- Where
- Spain
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid