Clinical trials: Short-Sighted
Cataract, Myopia
VCSEL Based Optical Swept Source Biometry
Optical interferometric biometry is a non-invasive and highly precise method for measuring eye length and intraocular distances. The method already exists as commercial devices (e.g. IOLMaster, Carl Zeiss Meditec AG).
- Trial name
- VBOB (NCT06551480)
- Testing
- Biometry
- Where
- Austria
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Rainer Leitgeb
Children With Myopia, Treatment
Clinical Study on the Effectiveness of Diverse Segments Defocus Optimization in Spectacle Lenses for Slowing Myopia Progression
Clinical Trial The goal of this clinical trial is to evaluate the effectiveness of two types of Diverse Segments Defocus Optimization (D.S.D.O.) spectacle lenses in slowing myopia progression in children.
- Conditions
- Children With Myopia, Treatment, Multizone Lens Design for Myopic Defocus, Visual Quality
- Trial name
- NCT07323251
- Testing
- Diverse Segments Defocus Optimization (D.S.D.O.) spectacle lenses
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Beijing Tongren Hospital
Adolescent, Adult
Prospective Clinical Study of Retinal Microvascular Alteration After ICL Implantation
To observe the retinal microvascular alteration during 3 months follow-up after Implantable Collamer Lens (ICL) operation in moderate and high myopia patients using quantitative optical coherence tomography angiography (OCTA)…
- Conditions
- Adolescent, Adult, Human, Male
- Trial name
- NCT04443231
- Testing
- Optical Coherence Tomography Angiography
- Where
- China
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Refractive Error - Myopia Axial, Astigmatism
Refractive Accuracy of "2WIN" and Portable Autorefractors
Youth and some adults have photoscreening refractions and hand-held auto refraction before cycloplegia refraction during new and follow up eye examinations.
- Conditions
- Refractive Error - Myopia Axial, Astigmatism, Accomodation, Visual Impairment
- Trial name
- NCT04249505
- Testing
- "2WIN" Photoscreener, "Plusoptix A12", "Retinomax"
- Where
- United States
- Volunteers
- 708 people, healthy volunteers welcome
- Sponsor
- Alaska Blind Child Discovery
Myopia
A 3-year Cross-sectional Assessment of the Tianjin Child and Adolescent Large-scale Eye Study
This is a school-based, cross-sectional study to assess the incidence and prevalence, risk factors of myopia among schoolchildren in both eye-use environment, eye-use habits, lifestyle, and family and subjective factors before…
- Trial name
- NCT05967702
- Where
- China
- Volunteers
- 126,810 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Myopia
Choroidal Changes Post Short Term Exposure To Virtual Reality Devices
This is a prospective, randomized, controlled, contralateral eye, clinical study. The objective of the study is to determine the impact of Virtual Reality (VR) usage on choroidal thickness when viewed through a test display…
- Trial name
- MIRABILE (NCT04140877)
- Testing
- Visu
- Volunteers
- healthy volunteers welcome
- Sponsor
- Visu, Inc.
Myopia, Hyperopia
Comparing Low-cost Handheld Autorefractors - a Practical Approach to Measuring Refraction in Low Resource Settings
Study compares four portable vision measurement and eye-imaging technologies in terms of accuracy and time and ease of use with older adult (ages 40-100) participants in a developing-country setting (India).
- Trial name
- NCT03456245
- Testing
- Vision device validation
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Myopia
Effect of Vision Therapy in Myopic Children With Poor Accommodative Response
This study aims to determine the treatment effect of vision therapy on myopic children by assessment of accommodative function before and after therapy.
- Trial name
- NCT03006601
- Testing
- Office-based accommodative/vergence therapy
- Where
- China
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Myopia
IntraLase vs Hansatome Flaps in LASIK
This study compared the clinical outcomes between fellow eyes randomized to either IntraLase femtosecond laser-created flaps or Hansatome mechanical keratome-created flaps during wavefront-guided laser in situ keratomileusis.
- Trial name
- NCT00691431
- Testing
- LASIK
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Stanford University
Myopia, Astigmatism
A Study to Investigate the Safety and Effectiveness of Aspheric Laser Refractive Surgery Treatments for Myopia
The objective of this study was to compare the safety and effectiveness of two versions of the Bausch \& Lomb Zyoptix Tissue Saving Aspheric Algorithm versus the current Zyoptix Tissue Saving Algorithm when used for myopia and…
- Trial name
- NCT00365677
- Testing
- The Bausch & Lomb Zyoptix Tissue Saving Aspheric algorithm, The Bausch & Lomb Zyoptix Tissue Saving algorithm
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Visual Acuity
Characterizing Successful Myopic Multifocal Contact Lens Wearers
This will be a prospective, single group, single-arm, and bilateral dispensing study. Subjects will be assigned to a single study lens type to be worn bilaterally in daily wear, and daily disposable modality, for at least 6 hours…
- Trial name
- NCT04178772
- Testing
- Acuvue Moist Multifocal Contact Lens JJVC Marketed Contact Lens
- Where
- Canada
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia
Choroidal Response to the Modified Defocus Incorporated Multiple Segments Spectacle Lenses
The goal of this study is to investigate the short-term changes in choroidal thickness and efficacy of the study spectacle lenses in children.
- Trial name
- NCT07547072
- Testing
- Modified Defocus Incorporated Multiple Segments lens (D1), Modified Defocus Incorporated Multiple Segments lens (D2)
- Where
- Hong Kong
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Myopia, Hyperopia
Multicenter Dispensing Study of Biofinity Lenses in Extended Range
To obtain subjective and objective feedback on the clinical performance of Biofinity lenses after at least two weeks daily wear in existing contact lens wearers compared with their habitual lenses.
- Trial name
- NCT02060539
- Testing
- Biofinity XR
- Where
- 4 sites in United States, Canada
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia
Evaluation of Wear Experience With One Week Reusable Contact Lenses in Habitual Two Week Reusable Lens Wearers
This open-label study is of current Acuvue® Oasys® wearers (2 - week replacement, reusable lenses) who are satisfied with their current lenses.
- Trial name
- NCT06382064
- Testing
- Biweekly replacement contact lenses, One week replacement contact lenses
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Myopia
Impact of Electronic Devices on Myopia Development and Progression
The aim of the stuy is to investigate the effects of the adoption of a curriculum with electronic devices for teaching materials and textbooks in Hong Kong schoolchildren on their changes in refractive error and visual function.
- Trial name
- NCT02150421
- Where
- China
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Myopia
Performance of DAILIES TOTAL1 Daily Disposable Contact Lenses in Habitual Soft Lens Wearers Who Report Substantial Digital Device Use
The purpose of this study is to evaluate the performance of DAILIES TOTAL1 daily disposable contact lenses with regards to subjective symptoms (comfort, dryness, vision) in lens wearers who use identify themselves as substantial…
- Trial name
- FOX (NCT06308666)
- Testing
- Delefilcon A contact lenses
- Where
- Canada
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of Waterloo
Refractive Errors
Clinical Evaluation of Acuity 200 (Fluoroxyfocon A) RGP Contact Lens
The objective of this clinical investigation is to collect valid scientific safety and effectiveness data on the Acuity 200 (fluoroxyfocon A) Rigid Gas Permeable Contact Lens, manufactured from a newly developed rigid gas…
- Trial name
- Acuity 200 (NCT03971227)
- Testing
- Acuity 200 (Fluoroxyfocon A) contact lens, Acuity 100 (Hexafocon A) contact lens
- Where
- 3 sites in United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Acuity Polymers, Inc.
Myopia, Orthokeratology
Effectiveness of Myopia Control by Breath-O Correct Orthokeratology Lenses
This is a 24-month longitudinal randomized controlled trial aiming to evaluate the effectiveness of myopia control by Breath-O correct orthokeratology lenses in different myopia progression groups classified according to their…
- Trial name
- NCT03919396
- Testing
- Breath-O orthokeratology lenses
- Where
- Hong Kong
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Myopia
Safety and Tolerability Evaluation of PRO-230 Ophthalmic Solution
Phase I Study to evaluate safety and tolerability of PRO-230 (atropine sulphate 0.05%) ophthalmic solution through evaluation of incidence of non-expected adverse events (AE), photophobia, pupillary diameter, incidence of…
- Trial name
- PRO-230 (NCT05481489)
- Testing
- Atropine Sulfate
- Volunteers
- healthy volunteers welcome
- Sponsor
- Laboratorios Sophia S.A de C.V.
Low Vision, Age Related Macular Degeneration
Early Feasibility Study Using IOPCL MAG to Improve Near Vision in ARMD Subjects
This early feasibility study aims to improve near vision in subjects 55 years or older who have a clinical diagnosis of Age-Related Macular Degeneration.
- Trial name
- NCT04984590
- Testing
- IOPCL AMD MAG
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- OnPoint Vision Inc