Clinical trials: Short-Sighted
Myopia Progressing
Myopia Control With a Innovative Spectacle Lens - A Cessation Study
The purpose of this study is to quantify myopic progression following cessation of a innovative spectacle lenses after 3 years' use.
- Trial name
- NCT06884527
- Testing
- Single Vision Lens to A innovative spectacle lens
- Where
- 5 sites in United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Essilor International
Glaucoma, Diabetic Retinopathy (DR)
"My Eyes, My Light": Amar Chokh, Amar Alo
Eye disease affects 2.2 billion people globally, which in turn adversely affects schooling, economic productivity, and participation in social life.
- Conditions
- Glaucoma, Diabetic Retinopathy (DR), Hypertensive Retinopathy, Cataract
- Trial name
- ACA2 (NCT07135570)
- Testing
- Multimodal Screening for Eye Disease, cataract surgery
- Where
- Bangladesh
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Data Yakka, Inc.
Must be PRK Candidate
Safety and Efficacy of Lotemax Versus FML in Subjects Undergoing PRK for the Correction of Mild to Moderate Myopia, 3- Month Follow-up Study
STUDY OBJECTIVE: To evaluate and compare the safety and efficacy of (corneal Wound Healing and Intraocular Pressure) Fluorometholone and Loteprednol after photorefractive keratectomy (PRK) surgery.
- Trial name
- NCT02974387
- Testing
- Fluorometholone(FML), Loteprednol (Lotemax)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Dr Salouti Eye Research Center
Myopia, Refractive Error - Myopia
Minimum Power and Frequency of Repeated Low-level Red-light to Effectively Control Myopia Progression
To explore the minimum power and frequency of Repeated Low-level Red-light (RLRL) to control myopia progression in low-myopic children aged 8-10 years, and the rebound effect of low-myopic children after discontinuation of RLRL…
- Conditions
- Myopia, Refractive Error - Myopia, Choroidal Thickness, Retina
- Trial name
- NCT06717048
- Testing
- Repeated Low-level Red-light, Red LED
- Where
- China
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Myopia
Assessment of Bifocal and Prismatic Bifocal Spectacles for Myopia Control in Children
1. To determine if the effect of near-addition lenses (bifocals) is more prominent for children with high myopia progression. 2.
- Trial name
- NCT00787579
- Testing
- Bifocal spectacles, Prismatic bifocal spectacles
- Where
- Canada
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Essilor International
Myopia, Astigmatism
A Comparison of LASIK Outcomes Using Two Femtosecond Lasers
Comparing LASIK outcomes using two femtosecond lasers
- Trial name
- NCT03063164
- Testing
- Intralase IFS150, Visumax
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Edward E. Manche
Presbyopia
Safety & Efficacy of Pilocarpine Ophthalmic Spray for Temporary Improvement of Near Vision in Presbyopic Adults
Volunteer participants are evaluated for eligibility during a Screening Visit; those meeting study inclusion/exclusion criteria are scheduled for 2 treatment visits.
- Trial name
- VISION-2 (NCT05114486)
- Testing
- Pilocarpine Ophthalmic administered with the Optejet dispenser
- Where
- 9 sites in United States
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Eyenovia Inc.
Myopia
Comparison of Efficacy Between Two Myopia Control Lenses
This is a one-year, mono-centre, randomize, double-masked, monocular cross-over clinical trial designed to test and compare the efficacy of the new lens design in slowing down the increase of axial length and controlling myopia…
- Trial name
- NCT06148870
- Testing
- Myopia Control Lens-1 (MCL1), Myopia Control Lens-2 (MCL2)
- Where
- Singapore
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Essilor International
Myopia
Discontinuation of Lens Wear in New Ortho-k Children (DOEE2)
This study aims at investigating the efficacy of myopic control using ortho-k in younger and older children.
- Trial name
- DOEE2 (NCT01236755)
- Testing
- single-vision glasses, ortho-k lenses
- Where
- China
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Presbyopia, Refractive Errors
Safety and Efficacy of a Sub-epitheilal Transform™ Corneal Allograft (TCA) for Presbyopia Correction
The objective of this clinical study is to evaluate the safety and effectiveness of subepithelial implantation of the Allotex TransForm corneal allograft (TCA) for improving near vision in presbyopic subjects.
- Trial name
- NCT03675438
- Testing
- Sub-epitheilal TCA Inlay
- Where
- 11 sites in Austria, Belgium and 4 more
- Volunteers
- healthy volunteers welcome
- Sponsor
- Allotex, Inc.
Myopia
Non-dispensing Fitting Study Comparing the Clinical Performance Hydrogel Sphere Design Contact Lenses.
The aim of this non-dispensing study is to evaluate the clinical performance of different hydrogel contact lens designs.
- Trial name
- NCT02727816
- Testing
- filcon IV I (BC 8.6), filcon IV I (BC 8.7), ocufilcon D
- Where
- Mexico
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Refractive Errors, Myopia
Correlation Between Preoperative Refraction and Anterior Segment Parameters With ICL Vault
This prospective non-comparative interventional study aims to analyse the pre-operative factors affecting the range of optimal ICL vaulting.
- Conditions
- Refractive Errors, Myopia, Myopic Astigmatism
- Trial name
- NCT05670626
- Testing
- Refractive Surgery
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Distance Viewing, Prolonged Near Viewing
Measuring How Quickly the Eye Focuses After Sustained Viewing of Close-up Images and Videos
In this experiment, subjects will view a cross pattern on the screen and be asked to focus their eyes on it. The cross pattern will look like it is moving towards and away from the eye in a back-and-forth motion.
- Trial name
- NCT07679048
- Testing
- Near viewing first, Distant viewing first
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Rochester Institute of Technology
High Myopia
Wuhan High Myopia Study
The study aims to observe the long-term changes of ocular（especially fundus） structure and visual function in patients with high myopia, so as to provide evidence for the prevention, diagnosis and prognosis of high myopia.
- Trial name
- LOVE-WH (NCT06162234)
- Testing
- observational
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Renmin Hospital of Wuhan University
Myopia, Astigmatism
Post-approval Study of New Enrolment Patients Undergoing Bilateral Treatment With the VisuMax SMILE Procedure
The objective of the post-approval study (PAS) is to assess patient experience of visual symptoms 6 months after bilateral treatment with the VisuMax SMILE procedure as measured by a patient questionnaire.
- Trial name
- NCT05740293
- Testing
- VisuMax SMILE procedure for the reduction or elimination of myopia with astigmatism
- Where
- 7 sites in United States
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- Carl Zeiss Meditec, Inc.
Myopia
The Different Design of Orthokeratology
In this study, we intend to enroll orthokeratology subjects aged 8-18 years old with binocular myopia up to and including -4.00 D.
- Trial name
- NCT05956704
- Testing
- Orthokeratology with aspheric wide inversion zone design in the optical zone, Orthokeratology with traditional spherical design in the optical zone
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Myopia
The Effect of Silicone Hydrogel Contact Lenses on Conjunctival Flora
The primary purpose of this study is to investigate the effect of silicone hydrogel contact lenses on conjunctival flora over a period of 6 months of daily wear.
- Trial name
- NCT00531375
- Testing
- Silicone hydrogel contact lens
- Where
- Australia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Melbourne
Myopia, Astigmatism
Wavefront-guided PRK vs Wavefront-optimized PRK
The purpose of the study is to compare the results of PRKK surgery when using wavefront-guided excimer laser treatment compared to wavefront optimized excimer laser treatment in patients with nearsightedness with and without…
- Trial name
- NCT02091934
- Testing
- Wavefront-guided PRK, Wavefront-optimized PRK
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Stanford University
Eye, High Myopia
Evaluation of Eye Health Benefits of Black Tomato Extract
Verification of the efficacy of black tomato extract for eye health.
- Trial name
- NCT06412393
- Testing
- Black tomato extract powder
- Where
- Taiwan
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- TCI Co., Ltd.
Myopia, Refractive Error
Comparative Study of Cycloplegic Refraction and Subjective Refraction With Fogging in School Age Children
A thorough ophthalmic examination of a child must include a refraction and this is often done with cycloplegia. In our study, we aim to determine at which age group a non-cycloplegic refraction technique closely correlates with a…
- Trial name
- NCT00347347
- Where
- Singapore
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Singapore National Eye Centre