Clinical trials: Short-Sighted
Visual Quality, Axial Length
The Influence of Axial Length on Visual Quality Following SMILE Surgery in Patients with High Myopia
This retrospective study aimed to investigate the subjective and objective visual outcomes following Small Incision Lenticule Extraction (SMILE) surgery in high myopic patients with varying axial lengths (AL).
- Conditions
- Visual Quality, Axial Length, High Myopia
- Trial name
- NCT06898164
- Testing
- This study does not involve any interventions
- Where
- China
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- yuhao shao
Myopia
Clinical Evaluation of Etafilcon A Contact Lenses Using a Novel Molding Process 2
This study is a multi-site, group sequential, adaptive, randomized, double-masked, 2×2 crossover design, 1-week dispensing study.
- Trial name
- NCT03701516
- Testing
- etafilcon A with novel molding process, etafilcon A with current molding process
- Where
- 12 sites in United States
- Volunteers
- 268 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Refractive Error - Myopia Bilateral
Clinical Performance of 59% Hioxifilcon A vs. Marketed Hydrogel Contact Lenses in Habitual Hydrogel Wearers
The study will compare the short-term clinical performance and wearer and practitioner acceptability of a new-to-market spherical daily disposable (DD) hydrogel soft contact lens to a currently marketed spherical DD hydrogel soft…
- Trial name
- NCT04986644
- Testing
- Hioxifilcon A standard hydrogel contact lens with Hyaluronic Acid (HA)
- Where
- 2 sites in United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Vision Service Plan
Myopia
The Impact of Bright Classroom on Myopia
This trial aims to test the effectiveness and practicality of study in the Bright Classrooms with skylight and artificial light renovation in reducing incident myopia in Chinese primary school children over three years, as…
- Trial name
- IMPACT (NCT05156190)
- Testing
- bright classrooms with light level over 1000 lux
- Volunteers
- healthy volunteers welcome
- Sponsor
- Queen's University, Belfast
Myopia
Clinical Trial of Orthokeratology Lens (MCOK-01)
A prospective, multicenter, randomized, controlled clinical trial of orthokeratology lens
- Trial name
- NCT06037850
- Testing
- Test orthokeratology lens, Control orthokeratology lens
- Where
- 3 sites in Singapore
- Volunteers
- 390 people, healthy volunteers welcome
- Sponsor
- Menicon Co., Ltd.
Myopia, Astigmatism
KLEx Versus FS-LASIK for the Treatment of Myopia and Compound Myopic Astigmatism
FemtoLASIK is a type of laser eye surgery used to correct vision problems such as nearsightedness, farsightedness, and astigmatism. It involves two main steps: creating a flap and reshaping the cornea.
- Conditions
- Myopia, Astigmatism, Myopic Astigmatism
- Trial name
- NCT06477081
- Testing
- FS-LASIK procedure, KLEx
- Where
- Mexico
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Instituto de Oftalmología Fundación Conde de Valenciana
Myopia
Evaluation of The Comfort of Orthokeratology Lenses Fit Using A New Software
As new orthokeratology fitting software emerges onto the market, it is of interest to assess their usefulness in guiding eye practitioners with lens fit.
- Trial name
- NCT05389072
- Testing
- control contact lens
- Where
- 4 sites in United States, Spain
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- CooperVision International Limited (CVIL)
Cataract
Comparative Study of Three IOL Power Calculation Formulae for Asian Eyes Shorter Than 22mm or Longer Than 25mm
Implantation of an intraocular lens is the gold standard in modern day cataract surgery. The appropriate lens power needed to achieve the desired refractive outcome can be calculated with a whole variety of formulas.
- Trial name
- NCT00347516
- Testing
- IOL calculation formula
- Where
- Singapore
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Singapore National Eye Centre
Myopia
Assessing the Impact of Streetscape Exposure on Children's Perception
The primary objective is to determine how streetscape exposure influences children's visual perception and psychological perception.
- Trial name
- NCT07761949
- Testing
- Virtual simulation of street visual environment exposure
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Myopia
Product Feasibility of a New Silicone Hydrogel Contact Lens
The objective of this study is to determine the clinical feasibility and to evaluate the product performance of investigational contact lens.
- Trial name
- NCT01309100
- Testing
- Investigational Lens, Acuvue Oasys Lens, Air Optix Aqua Lens
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Myopia, Juvenile Myopia
Efficacy in Controlling Myopia in Young Children Using a Novel Spectacle Lens
This is a conventional efficacy trial to validate the results from previous clinical trials for younger children; the 12-month efficacy results will be used to predict the 3-year treatment efficacy.
- Conditions
- Myopia, Juvenile Myopia, Myopia Progression
- Trial name
- EUCALYPTUS (NCT06034327)
- Testing
- Single vision, impact-resistant spectacle lenses; Test Arm, Single vision, impact-resistant spectacle lenses; Control Arm
- Where
- 14 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- SightGlass Vision, Inc.
Contact Lenses
Biometric Factors Changes Caused by Myopia Orthokeratology (OK) Lens
Subjects fit with VST or CRT type lens are reviewed 1 day to 2 year after first wearing the lens. Ocular examinations were performed, including slit-lamp biomicroscope, uncorrected distance visual acuity (UDVA), corrected…
- Trial name
- NCT05433259
- Testing
- Overnight orthokeratology
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Wenzhou Medical University
Myopia, Myopia; Refractive Error
Peripheral Relative Refractive Power of Orthokeratology Lenses
Orthokeratology (OK) has been demonstrated to be an effective intervention for slowing axial elongation in children with myopia.
- Trial name
- NCT07294404
- Testing
- orthokeratology
- Where
- China
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Myopia
A Two-Week Crossover Dispensing Evaluation Of Orion Daily Wear Soft Contact Lens
The primary objective of the study is to evaluate the clinical performance of test lens (Orion) in comparison with control lens (Gemini) over a period of two weeks of wear.
- Trial name
- NCT04585646
- Testing
- Orion daily disposable contact lens, Gemini daily disposable contact lens
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia
Comparison of Efficacy Between Two Myopia Control Lenses
This is a one-year, mono-centre, randomize, double-masked, monocular cross-over clinical trial designed to test and compare the efficacy of the new lens design in slowing down the increase of axial length and controlling myopia…
- Trial name
- NCT06148870
- Testing
- Myopia Control Lens-1 (MCL1), Myopia Control Lens-2 (MCL2)
- Where
- Singapore
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Essilor International
Myopia
Evaluation of Epi-lasik in U.S. Army Personnel
The purpose of this study is to evaluate the safety and efficacy of Epi-Lasik in U.S. Army personnel who have naturally occurring myopia with or without astigmatism.
- Trial name
- NCT00413517
- Testing
- Epi-Lasik
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Walter Reed Army Medical Center
Myopia
Evaluation of Conventional Photorefractive Keratectomy (PRK) in U.S. Army Personnel, Substudy of: Initial Evaluation of Excimer Laser Keratorefractive Surgery in U.S. Army Personnel
The purpose of this study is to: 1. evaluate the safety and efficacy of conventional PRK in U.S. Army personnel who have naturally occurring myopia with or without astigmatism. 2.
- Trial name
- NCT00412568
- Testing
- Photorefractive Keratectomy (PRK)
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Walter Reed Army Medical Center
Myopia ≤ -6 Diopters or Myopic Astigmatism ≤ -4 Diopters
Outcomes of a New Trans-epithelial Photorefractive Keratectomy (Streamlight PRK) Compared to Conventional PRK Procedures
Photorefractive keratectomy (PRK) involves mechanical or alcohol assisted debridement of the epithelium that leads to potential basement membrane (BM) injury ,with resultant more significant haze and pain compared to laser…
- Trial name
- NCT04710082
- Testing
- Photorefractive keratectomy (PRK)
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Myopia, Refractive Errors
VisuMax Femtosecond Laser Small Incision Lenticule Extraction for the Correction of High Myopia
The purpose of this study is to validate the safety and effectiveness of treating myopia (short-sightedness) higher than -10D using small incision lenticule extraction (SMILE) with the VisuMax femtosecond laser.
- Trial name
- NCT02528123
- Testing
- Small incision lenticule extraction, Tobramycin and dexamethasone, Ofloxacin
- Where
- United Kingdom
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- London Vision Clinic
Myopia, Prevention and Control
Effectiveness of Digital Defocus Vision Training With Low-Concentration Atropine on the Prevention and Control of Myopia in Children: A Clinical Study
Based on existing theories of myopia development and progression, our preliminary work has leveraged the features of virtual reality (VR) technology to digitally simulate myopic defocus signals through image-based emulation.
- Trial name
- NCT07724210
- Testing
- For the experimental group,Virtual reality-based digital defocus training combined with 0.02% atropine eye drops, For the control group, one drop of 0.02% atropine eye drops was instilled into each eye at bedtime daily, combined with full-time wear of fully corrected multi-zone positive optical defocus (DIMS) spe
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Beijing Tongren Hospital