Clinical trials: Short-Sighted
Ametropia, Myopia; Refractive Error
The Objective of This Study is to Evaluate the Perfomance of a Photorefraction Device for Screening Ametropia in Children. Eligible Participants Will Undergo Multiple Refractive Error Measurements, Visual Acuity and Strabismus Assessments During a Single Evaluation Visit.
The goal of this clinical trial is to evaluate the performance of a photorefraction screener in terms of sensibility, sensitivity and accuracy on children aged 3 to 8 y.o.
- Conditions
- Ametropia, Myopia; Refractive Error, Myopia; Astigmatism
- Trial name
- NCT06882408
- Testing
- Photorefraction device under investigation, Comparator device, Tabletop auto-refractometer, Comparator device, portable photorefraction device
- Where
- 2 sites in France
- Volunteers
- 315 people, healthy volunteers welcome
- Sponsor
- Essilor International
Myopia
Peripheral Choroidal Layer Response
The study aims to examine how the vascular layer of the eyeball (choroidal layer) responds when part of the visual field is exposed to specially generated visual stimulus.
- Trial name
- NCT05132140
- Testing
- adaptive optics system
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Houston
Visual Impairment, Myopia
At-home Testing Refraction Results With Best Corrected Visual Acuity (BCVA) Outcomes in Adults
This study is aimed at examining the BCVA from try-on glasses constructed from measurements from the EyeQue VisionCheck.
- Conditions
- Visual Impairment, Myopia, Hyperopia, Astigmatism
- Trial name
- NCT04820218
- Testing
- With Try-on glasses
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- EyeQue Corp.
Myopia, Progressive
Safety, Tolerability and Pharmacodynamics Evaluation of CBT-009 Eye Drop
This is a Two-Stage Phase 1/2 study to evaluate the safety, tolerability and pharmacodynamics of CBT-009 eye drop in healthy volunteers.
- Trial name
- NCT05372991
- Testing
- CBT-009, Vehicle, Atropine Sulfate
- Where
- Australia
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Cloudbreak Therapeutics, LLC
Myopia
A Study to Evaluate the Performance of Two Designs of Soft Toric Lenses
The objective of the study is to evaluate the product performance of the Bausch + Lomb toric investigational contact lenses compared to the currently marketed PureVision toric contact lenses.
- Trial name
- NCT01309867
- Testing
- Investigational Toric Lens, PureVision Toric Lens
- Where
- United States
- Volunteers
- 302 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Myopia, Astigmatism
A Three-Phase Contralateral Comparison of Ray-Tracing Guided LASIK Versus Three Other Refractive Surgery Platforms to Correct Myopia or Myopia With Astigmatism
This purpose of this study is to compare a new form of LASIK called Ray Tracing Guided LASIK to 3 other forms of corneal refractive surgery: 1. KLEx (KeratoLenticule Extraction) using the Zeiss Visumax 800 Laser, 2.
- Trial name
- NCT07201298
- Testing
- Ray-Tracing Guided LASIK, Keratorefractive Lenticule Extraction (KLEx), WaveFront Optimized LASIK
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hoopes Vision
Keratitis, Myopia
Safety of Overnight Corneal Reshaping Lenses
This retrospective chart review study compares the incidence of corneal inflammation due to infection in children vs. adult patients wearing overnight corneal reshaping lenses.
- Trial name
- NCT01272271
- Volunteers
- 1,317 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Myopia
The Clinical Comparison of Narafilcon A and Stenfilcon A Contact Lenses
This study aims to compare the clinical performance and subjective acceptance of the narafilcon A lens with the stenfilcon A lens when used on a daily wear, daily disposable basis.
- Trial name
- NCT02920970
- Testing
- narafilcon A, stenfilcon A
- Where
- United Kingdom
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Eye, High Myopia
Evaluation of Eye Health Benefits of Black Tomato Extract
Verification of the efficacy of black tomato extract for eye health.
- Trial name
- NCT06412393
- Testing
- Black tomato extract powder
- Where
- Taiwan
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- TCI Co., Ltd.
Myopia
Contact Lens in Pediatrics (CLIP) in an Asian Population Study
To evaluate the safety, efficacy and physiological performance of daily disposable spherical and toric soft contact lenses in a vision-corrected population of children ages 8-11 years of age.
- Trial name
- CLIP (NCT00473304)
- Testing
- Johnson&Johnson Acuevue daily disposable lenses
- Where
- Singapore
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Singapore National Eye Centre
Myopia, Esophoria
Bifocal Soft Contact Lenses and Their Effect on Myopia Progression in Children and Adolescents.
The purpose of this study is to determine whether bifocal soft contact lenses are effective in controlling the progression of myopia in children and adolescents that exhibit a tendency to excessively cross their eyes while…
- Conditions
- Myopia, Esophoria, Fixation Disparity
- Trial name
- NCT00214487
- Testing
- Bifocal Contact Lenses
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Aller, Thomas A., OD
Visual Acuity
Evaluation of a Daily Disposable Novel Multifocal Contact Lens in a Myopic Population; Part 2
This is a 6-visit, subject-masked, multi-site, 2×3 crossover dispensing trial that will last approximately 2 - 4 months.
- Trial name
- NCT04615507
- Testing
- JJVC Investigational Multifocal Contact Lens, Dailies Total 1® Multifocal Contact Lens
- Where
- 6 sites in United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia, Hypermetropia
Anesthetic Impregnated Bandage Soft Contact Lens (BSCL) in Pain Management After Photorefractive Keratectomy (PRK)
Compared to laser-assisted in situ keratomileusis (LASIK), Photorefractive Keratectomy (PRK) is associated with more discomfort and requires more downtime.
- Conditions
- Myopia, Hypermetropia, Refractive Errors, Astigmatism
- Trial name
- NCT04283331
- Testing
- Proparacaine Ophthalmic
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Beeran Meghpara, MD
Myopia, Hyperopia
Evaluation of the Performance of Monthly Replacement Sphere Lens Designs in Habitual Soft Contact Lens Wearers
The objective of the study is to evaluate the clinical performance of two monthly silicone hydrogel contact lenses in habitual wearers of frequent replacement (FRP) lenses when worn for one month.
- Trial name
- NCT05114564
- Testing
- Lens A (comfilcon A lens), Lens B (lehfilcon A lens)
- Where
- 4 sites in United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia
Examination of Myopia Progression and Soft Bifocal Contact Lens Myopia Control
This project intends to provide important, previously unmet answers regarding biological associations with myopia (nearsightedness) progression in order to improve the ability to predict patients who are most likely to benefit…
- Trial name
- BLINK2 (NCT04080128)
- Testing
- Contact lenses
- Where
- 2 sites in United States
- Volunteers
- 248 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Myopia
Myopic Control for High Myopes Using Orthokeratology
The purpose of this study is to evaluate and compare the eyeball elongation in high myopic children using partial correction orthokeratology and single-vision spectacles.
- Trial name
- HM-PRO (NCT00977236)
- Testing
- Orthokeratology lenses, Single-vision spectacle lenses
- Where
- China
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Central Retinal Vein Occlusion With Macular Edema
Use of Ziv Aflibercept in Different Retinal Diseases
A prospective interventional case series study was conducted on 20 eyes of 20 patients with active myopic choroidal neovascularisation (CNV) ,20 eyes with resistant diabetic macular edema and 15 eyes with non ischaemic central…
- Trial name
- NCT04290195
- Testing
- Ziv-Aflibercept 25 MG/ML [Zaltrap]
- Where
- Egypt
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Amin El Sayed Nawar
Myopia
Change in Choroidal Thickness of Myopic Eyes With a Myopia Control Contact Lens
In this study, the direct effect of the MiSight contact lens (Cooper Vision), a daily disposable contact lens recently approved in Germany for the treatment of myopia, will be investigated.
- Trial name
- NCT06636019
- Testing
- Myopia control contact lens
- Where
- Germany
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Hospital Augsburg
Presbyopia
Safety & Efficacy of Pilocarpine Eye Solutions for Temporary Improvement of Near Vision in Presbyopic Adults
Volunteer participants are evaluated for eligibility during a Screening Visit; those meeting study inclusion/exclusion criteria are scheduled for 3 treatment visits.
- Trial name
- VISION-1 (NCT04657172)
- Testing
- Pilocarpine Ophthalmic
- Where
- 9 sites in United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Eyenovia Inc.
Calculation of Intraocular Lens in High Myopic Cataractous Patients
Comparison Between Different Investigations Used in Intraocular Lens Calculation in High Myopic Cataractous Patients
the purpose of the study is to compare the accuracy of optical and ultrasonic biometry in intraocular lens (IOL) calculation in high myopic cataractous patients
- Trial name
- NCT04952181
- Testing
- optical biometry, ultrasonic biometry
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sohag University