Clinical trials: Short-Sighted
Myopia
Wavelength Intervention for Nearsighted Kids
The goal of this clinical trial is to learn if daily brief periods of specialized soft contact lens wear work to slow the progression of nearsightedness in children.
- Trial name
- WINK (NCT06598423)
- Testing
- Specialized soft contact lens 1, Specialized soft contact lens 2
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Juvenile Myopia, Myopia
Assessment of DOT Spectacles in Chinese Children Extension
This is a randomized, controlled, open-label, evaluator-blinded, multicenter, clinical trial of 12-months duration to evaluate the continued safety and efficacy of Diffusion Optics Technology (DOT) spectacle lenses in reducing…
- Trial name
- CATHAY Ext (NCT07008001)
- Testing
- Novel spectacle lens design
- Where
- 5 sites in China
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- SightGlass Vision, Inc.
Refractive Errors
Customized PRK With Mitomycin Versus Customized Lasik for Myopic Astigmatism
The present study was designed to compare the use of mitomycin in PRK for the treatment of refractive errors and to compare these results to customized Lasik
- Trial name
- NCT00365040
- Testing
- Prk with mitomycin vs Lasik
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Myopia,, Hyperopia,
Refraction Determination Analysis
Correlating the accuracy of a refraction done over telemedicine to that of a standard refraction, with a study hypothesis that the results will be equivalent.
- Conditions
- Myopia,, Hyperopia,, Astigmatism,, Presbyopia,
- Trial name
- NCT01995435
- Testing
- Telemedicine refraction, Traditional refraction
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Lee, Steven, M.D.
Myopia
Delaying the Onset of Nearsightedness Until Treatment (DONUT) Clinical Trial
The aims of this clinical trial will test whether or not the onset of nearsightedness is delayed in a group of children randomized to nightly drops in 0.05% atropine in both eyes, in comparison to children who receiving nightly…
- Trial name
- DONUT (NCT07567040)
- Testing
- Atropine Sulfate 0.05% Oph Soln
- Where
- 13 sites in United States
- Volunteers
- 664 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Myopia, Myopia, Progressive
Multicenter RCT: LED Red Light Dose-Response in Myopia Progression Control
The goal of this clinical trial is to verify the effectiveness and safety of non-laser LED red light combined with defocus lens therapy for controlling myopia progression and evaluate the impact of different intervention…
- Trial name
- NCT07330180
- Testing
- Yingtong Vision Rehabilitation Instrument, Hoya DIMS multi-point myopia defocus lens
- Where
- 7 sites in China
- Volunteers
- 364 people, healthy volunteers welcome
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Presbyopia
Using AGN-190584 in Subjects Utilizing Single -Use Daily, Contact Lenses
AGN-190584 has gone through many clinical trials showing its safety and effectiveness in individuals from 40-55 years of age. There has been no published data on the use of this product in individuals corrected with contact…
- Trial name
- NCT05624320
- Testing
- AGN-190584
- Volunteers
- healthy volunteers welcome
- Sponsor
- Gordon Schanzlin New Vision
Posterior Capsule Opacification
Posterior Capsule Opacification (PCO) With AcrySof Single-Piece IOL
The purpose of this study what to evaluate if axial myopia might influence the development of PCO.
- Trial name
- NCT00855491
- Testing
- Phaco
- Where
- India
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Iladevi Cataract and IOL Research Center
Myopia Progression
Effectiveness of Orthokeratology in Decreasing Myopic Progression in a Young Adult Population Enrolled in a Professional Optometric Curriculum
The high prevalence of myopia - especially in Asian countries - is well documented, as are the sight-threatening complications of high or degenerative myopia.
- Trial name
- NCT02623543
- Testing
- OrthoK
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Illinois College of Optometry
Myopia
Comparing Relative Peripheral Refraction on Myopia Progression
The investigators will test our hypothesis that parameters on peripheral defocus can regulate eye growth: For instance, the relative peripheral refraction measured by Multispectral Refraction Topography (MRT) would be significant…
- Trial name
- CMPMRT (NCT06758843)
- Testing
- measure the axial length, visual acuity, and refraction at follow-up of 6- and 12-month
- Where
- China
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Fuzhou Southeast Institute of Visual Ophthalmology
Myopia, Hyperopia
Comparison of Acular LS Versus Nevanac for Pain Control in Eyes Undergoing PRK
To determine the ability of two topical Nonsteroidal Anti-inflammatory drops (Acular LS \& Nevanac) to help control pain following Photorefractive Keratectomy (PRK).
- Trial name
- NCT00347204
- Testing
- ketorolac (Acular LS), Nepafenac (Nevanac)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Center For Excellence In Eye Care
Refractive Surgery, Refractive Error - Myopia
Evaluate the Safety and Effectiveness of the AccuraSee™ IOPCL for Secondary Implantation in the Capsular Bag to Improve Near and/or Intermediate Vision Following Previous Cataract Surgery
This is a study to evaluate the safety and effectiveness of the AccuraSee™ intraocular pseudophakic capsular lens (IOPCL) to improve near and/or intermediate vision following previous cataract surgery.
- Trial name
- NCT06625749
- Testing
- Accurasee™ IOPCL
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- OnPoint Vision Inc
Myopia
To Evaluate the Efficacy and Safety of Multifocal Soft Contact Lens in Myopia Control
The objective of this study is to investigate the efficacy and safety of soft lens in myopia control.
- Trial name
- NCT03413085
- Testing
- soft contact lens
- Where
- 3 sites in Taiwan
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Largan Medical Co., Ltd.
Pain, Vision Nearsighted
Post Photorefractive Keratectomy (PRK) Use of an Eye Shield for Maintaining Vision and Mitigating Pain
The purpose of this research is to determine if an investigational thin shield over the cornea can safely and effectively reduce or eliminate pain following Post Photorefractive Keratectomy (PRK).
- Trial name
- Nexis-CS0032 (NCT01592643)
- Testing
- Eye Shield
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Stanford University
Myopia
Retardation of Myopia in Orthokeratology
The primary aim of this study is to evaluate and compare the eyeball elongation in children wearing orthokeratology lenses and single-vision spectacles.
- Trial name
- ROMIO (NCT00962208)
- Testing
- orthokeratology lenses, single-vision spectacle lenses
- Where
- China
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Myopia, Ametropia
LED Low-Intensity Red Light for Myopia Control in Youth: Efficacy and Safety Study
The purpose of this clinical trial was to investigate the efficacy and safety of repetitive low-intensity single-wavelength red light from an LED light source in controlling myopia progression in children and adolescents.
- Trial name
- NCT07375589
- Testing
- Red light treatment with 1.6mW LED light source, Red light treatment with 0.001mW LED light source
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Myopic Progression
A 2-year Longitudinal Study on the Structural and Optical Effects of Orthokeratology Treatment on Eye
This is a two-year longitudinal study investigating the optical and structural effects of increased compression factor of orthokeratology lens on eyes and the corresponding effect on change in choroidal thickness and therefore…
- Trial name
- NCT02643342
- Testing
- Orthokeratology
- Where
- China
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Myopia
Safety and Effectiveness of Wavefront-Guided LASIK Corrections of Myopic Refractive Errors
The purpose of this clinical trial is to demonstrate that wavefront-guided LASIK is safe and effective for the correction of myopic refractive errors.
- Trial name
- NCT01663363
- Testing
- LASIK correction of myopic refractive errors
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Myopia, Hyperopia
Complete Easy Rub Comparative Efficacy Study
The aim of this trial is to assess Complete Easy Rub compared to a competitor multi-purpose solution in terms of lens cleanliness, subjective response and ocular response, when lenses are worn bilaterally on a daily wear basis…
- Conditions
- Myopia, Hyperopia, Astigmatism
- Trial name
- NCT01019564
- Testing
- Complete Easy Rub Formula MPS, Aquify MPS
- Volunteers
- healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Eye--Refractive Errors
Effect of Using Myopia Prediction Algorithm
In this study, the investigators aim to perform a prospective, randomized controlled study to compare the myopia development between children using myopia prediction algorithm and children without using myopia prediction…
- Trial name
- NCT04005014
- Testing
- Myopia prediction algorithm
- Volunteers
- 1,680 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University