Clinical trials: Shoulder Arthroplasty
Osteoarthritis Shoulder
TSA v RSA in Osteoarthritic Shoulders With Greater Than 15 Degrees of Retroversion
This study will compare total shoulder arthroplasty (TSA) with an augmented glenoid component and reverse shoulder arthroplasty (RSA) procedures, in participants with advanced glenohumeral osteoarthritis aged 65 years and older…
- Trial name
- SERVASA15 (NCT05487274)
- Testing
- Total Shoulder Arthroplasty + augmented glenoid component, Reverse Shoulder Arthroplasty
- Where
- Canada
- Volunteers
- 108 people
- Sponsor
- Ottawa Hospital Research Institute
Shoulder Osteoarthritis, Arthropathy Shoulder
Scapular Positioning in Standing Position Using Sonography
The objective of this study is to analyse the positioning of the scapula in standing position and compared to the supine position (CT scan) in 3 dimensions (3 rotations of the scapula) using a non-radiant, portable system…
- Trial name
- 3S (NCT04449146)
- Testing
- Scapular positioning in Standing position using Sonography
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Brest
Arthropathy Shoulder
TXA in Revision Total Shoulder Arthroplasty
This is a phase IV, randomized, single-blind, single-center study comparing calculated total blood loss, surgical drain output and hematoma formation in patients who receive 2 doses of Tranexamic Acid (TXA) versus control group…
- Trial name
- NCT04650698
- Testing
- Tranexamic acid (TXA) injection
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- NYU Langone Health
Avascular Necrosis, Humeral Fractures
CT Imaging Evaluation of Humerus Fractures
Displaced, multi-part intracapsular, proximal humerus fractures represent a major challenge for patients and orthopedic surgeons.
- Trial name
- NCT02170545
- Testing
- Dual Energy Computed Tomography
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Virginia Commonwealth University
Shoulder Arthroplasty
Total Shoulder Arthroplasty Multi-Center Registry
The objective of the study is a multi-center prospective registry to collect clinical outcomes of anatomic and reverse total shoulder arthroplasty.
- Trial name
- NCT03511586
- Where
- 27 sites in United States, Germany and 2 more
- Volunteers
- 2,500 people
- Sponsor
- Arthrex, Inc.
Post Operative Pain, Anesthesia
Comparison of Interscalene Catheter to Single Injection Interscalene Blocks for Total Shoulder Arthroplasties
Comparison of post-operative pain after total shoulder surgery. The Principle Investigator will be comparing Exparel single shot block to Interscalene catheter
- Conditions
- Post Operative Pain, Anesthesia, Nerve Block, Shoulder Osteoarthritis
- Trial name
- NCT05868330
- Testing
- Interscalene Catheter, Exparel Single Shot Interscalene Block
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Melinda Seering
The Primary Disease Process Being Studied is Shoulder OA and the Effect of an All Polyethelene Glenoid Component on Shoulder Arthroplasty
This is a 2 Year Follow up Clinical and Radiographic Analysis of a Novel All Polyethelene Glenoid Component in Standard Total Shoulder Arthroplasty.
Two hundred patients will be analyzed both clinically (via validated outcomes measures) and radiographically (via 2 sets of standard radiographs) to determine the survival and degree of bone in growth of a novel all polyethelene…
- Trial name
- NCT01313741
- Testing
- Shoulder arthroplasty with anchor peg glenoid
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Knoxville Orthopedic Clinic
Osteoarthritis, Posttraumatic Arthrosis
Sidus Stem-Free Shoulder IDE Study
The purpose of this study is to determine if Sidus stem-free shoulder system is safe and effective when used in total shoulder replacement.
- Conditions
- Osteoarthritis, Posttraumatic Arthrosis, Rheumatoid Arthritis
- Trial name
- NCT01878253
- Testing
- Sidus Stem-Free Total Shoulder Arthroplasty System
- Where
- 11 sites in United States, Canada
- Volunteers
- 95 people
- Sponsor
- Zimmer Biomet
Anatomic Total Shoulder Arthroplasty
Use of Real Time Instrumentation (RTI) in Total Shoulder Arthroplasty
Glenoid component loosening is the most common complication of total shoulder arthroplasty. Loosening is associated with malposition of the implant as well as the quality of the glenoid bone.
- Trial name
- RTI (NCT01905241)
- Testing
- Anatomic TSA using RTI, Anatomic Total Shoulder Arthroplasty
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- The Cleveland Clinic
Sleep Disturbance, Shoulder Arthritis
Multimodal Sleep Pathway for Shoulder Arthroplasty
The purpose of the study is to investigate the efficacy of sleep medicine in the recovery of orthopaedic shoulder arthroplasty patients.
- Conditions
- Sleep Disturbance, Shoulder Arthritis, Arthroplasty Complications, Perioperative/Postoperative Complications
- Trial name
- NCT03269760
- Testing
- Zolpidem
- Where
- United States
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Osteoarthritis
Global® AP™ Total Shoulder Arthroplasty
This study will evaluate the clinical performance of DePuy Global® AP™ Shoulder prosthesis using the anchor pegged glenoid component and clinical and radiographic evaluations.
- Trial name
- NCT00719771
- Testing
- Global® AP™ Total shoulder arthroplasty
- Where
- 4 sites in United States
- Volunteers
- 64 people
- Sponsor
- DePuy Orthopaedics
Primary Anatomic or Reverse Total Shoulder Arthroplasty
Hydrogen Peroxide to the Wound Following Surgical Incision Affecting Cultures in Primary Shoulder Arthroplast
Cutibacterium acnes has been the focus of much recent shoulder literature, as it has been found to be both a common cause of periprosthetic joint infection as well as a common contaminant in shoulder surgery.
- Trial name
- NCT04609306
- Testing
- H2O2 application to incision
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Florida
Total Shoulder Arthroplasty, Osteo Arthritis Shoulders
Posterior Approach to Total Shoulder Arthroplasty
The purpose of this study is to evaluate preoperative objective measurements and operative objective measurements to determine if there is any effect to postoperative outcomes.
- Trial name
- pTSA (NCT03623269)
- Testing
- posterior approach to total shoulder arthroplasty
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- The Orthopaedic Research & Innovation Foundation
Staphylococcal Infections, Methicillin-resistant Staphylococcus Aureus
Daptomycin Use for Antimicrobial Prophylaxis in Methicillin Resistant Staphylococcus Aureus (MRSA) Colonized Adult Patients Undergoing Primary Elective Hip, Knee, or Shoulder Arthroplasty
This study will evaluate the safety and effectiveness of daptomycin, an antibiotic compared to another one which is vancomycin when given around the time of joint replacement surgery.
- Trial name
- NCT01196169
- Testing
- Daptomycin, Vancomycin
- Where
- 2 sites in United States
- Volunteers
- 28 people
- Sponsor
- Mountain Home Research & Education Corporation
Hip Osteoarthritis, Knee Osteoarthritis
Return to Golf After Orthopaedic Surgery
The GOLF study is a multicenter, prospective study with the goal to investigate golfers' return to the sport following hip, knee or shoulder arthroplasty.
- Conditions
- Hip Osteoarthritis, Knee Osteoarthritis, Shoulder Osteoarthritis
- Trial name
- NCT05675618
- Where
- 2 sites in United States, United Kingdom
- Volunteers
- 432 people
- Sponsor
- Hospital for Special Surgery, New York
Non-inflammatory Degenerative Joint Disease (NIDJD), Avascular Necrosis
Sidus(TM) Post Market Clinical Follow-up (PMCF) Study
This post market clinical follow-up study is designed to confirm safety and performance of the Sidus Stem-Free Shoulder when used in hemi or total shoulder arthroplasty.
- Conditions
- Non-inflammatory Degenerative Joint Disease (NIDJD), Avascular Necrosis, Osteoarthritis, Inflammatory Joint Disease (IJD)
- Trial name
- NCT01700543
- Testing
- Shoulder Arthroplasty
- Where
- 8 sites in Austria, France and 3 more
- Volunteers
- 152 people
- Sponsor
- Zimmer Biomet
Subscapularis Injury
Comparison of Two Methods of Subscapularis Management in Shoulder Arthroplasty: Tenotomy Versus Peel
What is the difference in subscapularis strength between two different methods of subscapularis mobilization: incision of the tendon (tenotomy) versus peel.
- Trial name
- NCT01404143
- Testing
- Subscapularis Tenotomy, subscapularis peel
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Ottawa Hospital Research Institute
Orthopedic Disorder
Physical Therapy After Reverse Total Shoulder Arthroplasty
A common operation for various shoulder conditions is a total shoulder arthroplasty (TSA). In cases with severe rotator cuff tears or other conditions, a variant of the procedure called a reverse total shoulder arthroplasty may…
- Trial name
- NCT03547726
- Testing
- Physical Therapy, Self-Rehab
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Alabama at Birmingham
Shoulder Injuries
Subscapularis Repair Augmentation for Total Shoulder Arthroplasty
The primary purpose of this research is to compare the images obtained by ultrasound between a standard repair of the subscapularis tissue and after repair with a Biobrace.
- Trial name
- NCT05487677
- Testing
- BioBrace Augmentation, Standard Repair with Sutures
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Stanford University
Glenohumeral Osteoarthritis, Proximal Humerus Fracture
Post-Market Clinical Follow-Up (PMCF) Study Evaluating the Safety and Efficacy of Tıpmed™ Shoulder Prosthesis System
This study is designed as a prospective, multicenter, observational post-market clinical follow-up (PMCF) study to evaluate the safety and effectiveness of the Tipmed™ Shoulder Prosthesis System at 12 months postoperatively.
- Conditions
- Glenohumeral Osteoarthritis, Proximal Humerus Fracture, Rotator Cuff Arthropathy, Rheumatoid Arthritis
- Trial name
- NCT07678034
- Testing
- Tipmed™ Reverse Shoulder Prosthesis System, Tipmed™ Shoulder Prosthesis System (Hemiarthroplasty Configuration)
- Where
- 4 sites in Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- TIPMED Medical Device Manufacturing Ltd. Co.