Clinical trials: Shoulder Pain
Shoulder Pain
The Efficacy of Local Anesthetics to Reduce Shoulder Pain Post-Steroid Injections
The specific aim of this prospective study is to determine whether local anesthetics prior to subacromial steroid injections reduce pain and consequently if they are cost-effective in the treatment for shoulder pathology.
- Trial name
- NCT02592629
- Testing
- lidocaine, ethyl chloride, Kenalog
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Milton S. Hershey Medical Center
Stroke, Shoulder Pain
Multimodal Treatment for Hemiplegic Shoulder Pain
Hemiplegic shoulder pain (HSP) affects up to 60% of moderate to severely impaired stroke survivors. HSP is associated with poor rehabilitation outcomes, including interference with activities of daily living (ADLs) and poor…
- Trial name
- NCT02893267
- Testing
- Peripheral Nerve Stimulation, Physical Therapy
- Where
- 3 sites in United States
- Volunteers
- 96 people
- Sponsor
- MetroHealth Medical Center
Shoulder Pain
Pain Increases After Shoulder Injection
Compare FLARE reactions (increase in VAS by two or more points) in the first 48 hours following a shoulder injection.
- Trial name
- NCT05438277
- Testing
- Methylprednisolone (MPA), Triamcinolone Acetonide (TA)
- Where
- United States
- Volunteers
- 421 people, healthy volunteers welcome
- Sponsor
- Campbell Clinic
Arthroscopic Shoulder Surgery, Pain, Postoperative
Examining the Effectiveness of a Connective Tissue Matrix Implant in Reducing Post-operative Pain and Narcotic After Outpatient Arthroscopic Shoulder Surgery
This document is a protocol for a human research study. This study is to be conducted according to United States standards of Good Clinical Practice in accordance with applicable Federal regulations and institutional research…
- Trial name
- ECM (NCT04633837)
- Testing
- Extracellular Matrix Graft Injectable Implant
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Brian Badman
Postoperative Pain
An International Trial to Evaluate the Efficacy and Safety of SABER®-Bupivacaine for Postoperative Pain Control in Patients Following Arthroscopic Shoulder Surgery
The objective is to identify the optimal dose of SABER-Bupivacaine for postoperative pain control in patients undergoing elective arthroscopic shoulder surgery on the basis of pharmacokinetics, efficacy and safety evaluations.
- Trial name
- NCT00993798
- Testing
- SABER-Bupivacaine Treatment 1a, Bupivacaine HCl Treatment 1c, SABER-Bupivacaine Treatment 2a
- Where
- 10 sites in Austria, Germany and 3 more
- Volunteers
- 107 people
- Sponsor
- Durect
Acute Pain, Surgery
Auriculotherapy for Surgical Pain
The current opioid epidemic has led to a renewed interest in exploring non-pharmacological techniques to treat post-operative pain.
- Conditions
- Acute Pain, Surgery, Shoulder Pain
- Trial name
- NCT03860259
- Testing
- Auriculotherapy cryopuncture device without nitrogen gas, Auriculotherapy cryopuncture device with nitrogen gas
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Jacques E. Chelly
Pain, Postoperative, Brachial Plexus Block
Liposomal Bupivacaine Single-Injection Interscalene Block vs. Continuous Interscalene Block for Primary Total Shoulder Arthroplasty
This study aims to assess analgesia efficacy between liposomal bupivacaine single injection interscalene blockade vs. continuous interscalene nerve block for patients undergoing primary total shoulder arthroplasty.
- Trial name
- NCT05005260
- Testing
- Bupivacaine HCl, Liposomal bupivacaine + Bupivacaine Hcl 0.5% Inj
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- Mayo Clinic
Shoulder Pain
Changes in Subjects With Posterior Capsule Tightness
To identify biomechanical and sensibility changes in people with posterior capsule tightness in people with and without shoulder pain.
- Trial name
- NCT02353442
- Testing
- Posterior shoulder mobilizations, External rotators strengthening, Scapular squeezing
- Where
- Brazil
- Volunteers
- 59 people
- Sponsor
- Universidade Federal de Sao Carlos
Frozen Shoulder
The Anti-Freaze-F Study- "Anti-TNF for Treatment of Frozen Shoulder - a Feasibility Study"
Frozen shoulder is a common condition affecting approximately 9% of people aged 25-64 years. During the early phase the pain is usually unbearable and the later restriction in movement is severely limiting.
- Trial name
- Anti-FreazeF (NCT05299242)
- Testing
- Adalimumab Injection
- Where
- 4 sites in United Kingdom
- Volunteers
- 9 people
- Sponsor
- University of Oxford
Shoulder Arthroplasty
Interscalene Block With Liposomal Bupivacaine vs. Interscalene Block With Bupivacaine and Adjuvants
The purpose of this study is to determine whether the use of plain bupivacaine with common adjuvants for interscalene block (ISB) provides non-inferior analgesic results compared to the use of liposomal bupivacaine for ISB, in…
- Trial name
- NCT03845894
- Testing
- Liposomal bupivacaine, Bupivacaine with adjuvants
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Rotator Cuff Injuries, Shoulder Pain
ASHCOM Shoulder System and Its Related Instruments
The objectives of this study are to confirm safety, performance and clinical benefits of the ASHCOM Shoulder System and its related instruments by analysis of standard scoring systems, radiographs and adverse event records.
- Conditions
- Rotator Cuff Injuries, Shoulder Pain, Arthropathy; Traumatic, Arthroplasty Complications
- Trial name
- NCT04258605
- Testing
- ASHCOM Shoulder System
- Where
- Italy
- Volunteers
- 24 people
- Sponsor
- Zimmer Biomet
Rotator Cuff Tear, Postoperative Pain
Oral Ketorolac for Arthroscopic Rotator Cuff Repair
1. The investigators aim to examine the use of IV and oral ketorolac as an adjunctive agent to the standard of care pain protocol for postoperative pain control following arthroscopic rotator cuff repair. 2.
- Trial name
- NCT03967847
- Testing
- Ketorolac
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University Hospitals Cleveland Medical Center
Shoulder Injury
Ropivacaine Block Alone or With Perineural or Systemic Dexamethasone for Pain in Shoulder Surgery
Pre-operative perineural injection of dexamethasone mixed with local anesthetic in peripheral nerve blockade for orthopedic surgery has been shown to prolong the length of analgesia, improve visual analog pain scores, decrease…
- Trial name
- NCT01450007
- Testing
- Ropivacaine, Dexamethasone, Normal saline
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Mayo Clinic
Musculoskeletal Pain
The Effect of Low Level Laser Therapy on Neck and Shoulder Pain
This study is to see if applying red and violet low level laser light to the neck and shoulders can help to reduce pain in the neck and shoulders.
- Trial name
- NCT03941912
- Testing
- Erchonia EVRL
- Where
- 2 sites in United States
- Volunteers
- 44 people
- Sponsor
- Erchonia Corporation
Spinal Cord Injury, Pain
Investigating Botulinum Toxin A to Treat Acute Neck/Upper Shoulder Pain Following a New Spinal Cord Injury.
As clinicians, it is often a struggle to find effective pain control for a certain subgroup of patients with tetraplegia. These patients often have severe upper back, neck, and shoulder pain, limiting rehabilitation productivity…
- Trial name
- NCT00320281
- Testing
- botulinum toxin A
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Craig Hospital
Postoperative Pain
A Safety and Effectiveness Study of SABER®-Bupivacaine for Pain Following Shoulder Surgery
This is a research study testing SABER-Bupivacaine (an experimental pain-relieving medication). SABER-Bupivacaine is designed to continuously deliver bupivacaine, a common local anesthetic, for a few days in order to treat local…
- Trial name
- NCT00818363
- Testing
- SABER-Bupivacaine
- Where
- 9 sites in Australia, New Zealand
- Volunteers
- 60 people
- Sponsor
- Durect
Stroke, Shoulder Pain
Peripheral Nerve Stimulation for Shoulder Pain: Dose Response
The primary objective of this RCT is explore the mechanism for Hemiplegic Shoulder Pain (HSP) reduction due to treatment with peripheral nerve stimulation.
- Trial name
- NCT02928055
- Testing
- Peripheral Nerve Stimulation
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- MetroHealth Medical Center
Pain
Liposomal Bupivacaine in Total Shoulder Arthroplasty
This is a randomized, single blinded, standard of care controlled clinical trial. All adult patients over eighteen desiring shoulder arthroplasty will be eligible.
- Trial name
- EXP-TSA (NCT02570022)
- Testing
- Liposomal bupivacaine, Inter-scalene nerve block, Ropivacaine
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Postoperative Pain, Total Shoulder Arthroplasty
Cohort 1 (TSA) of: A Multi-surgery Assessment of ZYNRELEF (HTX-011)
Cohort 1 (subjects undergoing total shoulder arthroplasty, TSA) of a Phase 4, randomized, blinded, active-controlled, multicohort study to evaluate HTX-011 compared with bupivacaine HCl in subjects undergoing different surgical…
- Conditions
- Postoperative Pain, Total Shoulder Arthroplasty, Multimodal Analgesia
- Trial name
- AMAZE (NCT06109415)
- Testing
- HTX-011, Bupivacaine Hydrochloride, MMA regimen
- Where
- 5 sites in United States
- Volunteers
- 30 people
- Sponsor
- Heron Therapeutics
Shoulder Pain Chronic
An Implantable Microneuromodulator for the Treatment of Chronic Shoulder Pain in Chronic Post-Stroke Subjects
The goal of this research study is to investigate safety and gather initial effectiveness data for a new implanted device designed to treat chronic shoulder pain in chronic post-stroke subjects.
- Trial name
- BBPM (NCT00567541)
- Testing
- Battery Powered Microneuromodulator (BBPM)
- Where
- 3 sites in United States
- Volunteers
- 16 people
- Sponsor
- Bioness Inc