Clinical trials: Shunt Malfunction
End Stage Renal Disease, Catheter Infection
AUSTrian Randomized Interventional Study on Dialysis Accesses
Patients with diagnosed end stage renal disease and indication for chronic dialysis rely on a well-functioning access for dialysis.
- Conditions
- End Stage Renal Disease, Catheter Infection, Shunt Malfunction
- Trial name
- AUSTRIA (NCT03764358)
- Testing
- Arteriovenous Fistula, Tunneled Cuffed Catheter
- Where
- Austria
- Volunteers
- 220 people
- Sponsor
- Medical University of Vienna
End Stage Liver Diseases
Analysis of Respiratory System Mechanics and Inflammatory Response During Orthotopic Liver Transplantation (SPPLIT Trial)
During orthotopic liver transplantation (OLT), respiratory system function may be severely impaired for several reasons including anaesthesia effects, hyperdynamic volume state with fluid overload and ischemia reperfusion injury.
- Trial name
- SPPLIT (NCT02119585)
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of Turin, Italy
Congestive Heart Failure, Ascites
The Automated Fluid Shunt (AFS)in Chronic Congestive Heart Failure
A 28-week, feasibility study to investigate the safety and efficiency of the Automatic Fluid Shunt in patients with chronic congestive heart failure, ascites and diuretic resistance.
- Trial name
- NCT00907673
- Testing
- Automatic Fluid Shunt System
- Where
- Sweden
- Volunteers
- 2 people
- Sponsor
- NovaShunt AG
Heart Failure
ALT-FLOW II Trial of the Edwards APTURE Transcatheter Shunt System
This is a prospective, multi-center, randomized, sham-controlled, double-blinded (participant and outcomes assessor) clinical trial.
- Trial name
- ALT-FLOW II (NCT05686317)
- Testing
- Edwards APTURE transcatheter shunt system
- Where
- 25 sites in United States, Brazil and 3 more
- Volunteers
- 100 people
- Sponsor
- Edwards Lifesciences
Heart Failure With Reduced Ejection Fraction (HFrEF)
RELIEVE METAB Study
This prospective, single-center post-market-follow-up study aims to fill knowledge gaps by combining advanced cardiac MRI/MRS with systemic mitochondrial assays and exercise testing to characterize the energetic and functional…
- Trial name
- NCT07555925
- Testing
- cardiac MRI, Functional Testing
- Where
- Germany
- Volunteers
- 15 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
Portal Hypertension Related to Cirrhosis
Small Diameter TIPS in Patients with Severe Liver Atrophy and Variceal Bleeding
Portal hypertension is the most common complication in patients with end-stage liver cirrhosis. Portal hypertension-related complications, such as variceal bleeding, often lead to a poor prognosis.
- Trial name
- NCT06589531
- Testing
- During TIPS operation, shunt diameter or diameter of covered stent
- Volunteers
- 120 people
- Sponsor
- Huang Mingsheng
Heart Failure
Alleviate-HF-1 Study
Patients with heart failure and preserved left ventricular ejection fraction (HFpEF, EF ≥ 50%) or mid-range left ventricular ejection fraction (HFmrEF, 40% < EF < 50%) with mild to moderate functional limitation will be evaluated…
- Trial name
- NCT04583527
- Testing
- ALV1 System
- Where
- Georgia
- Volunteers
- 15 people
- Sponsor
- Alleviant Medical, Inc.
Glaucoma
Does Adding Bevacizumab Therapy in Glaucoma Surgery Improve the Success of Needle Bleb Revisions?
The purpose of this study is to see if a new add on (or adjunctive) therapy used in glaucoma surgery improves the success of needle bleb revisions.
- Trial name
- Avastin (NCT00853073)
- Testing
- bevacizumab, balanced salt solution
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Wills Eye
Hydrocephalus, Shunt Malfunction
Comparison of Continuous Noninvasive and Invasive Intracranial Pressure Measurement--Celda Infusion Subprotocol
This research is being done to determine the accuracy of two noninvasive methods of measuring the pressure of the spinal fluid, also known as intracranial pressure (ICP).
- Trial name
- NCT01976559
- Testing
- Tympanic Membrane Displacement (TMD), DPOAE
- Where
- Sweden
- Volunteers
- 15 people
- Sponsor
- LifeBridge Health
Heart Failure
NoYA RAISE Trial II (Radiofrequency Ablation-Based Interatrial Shunt for Heart Failure)
A Prospective, Multiple Center, and Objective Performance Criteria Study to Evaluate the NoYA™ Radiofrequency Interatrial Shunt System manufactured by NoYA Medtech (Hangzhou) Co., Ltd.
- Trial name
- NCT05375110
- Testing
- NoYA™ Radiofrequency Interatrial Shunt System
- Where
- 31 sites in China
- Volunteers
- 120 people
- Sponsor
- Hangzhou NOYA MedTech Co. Ltm.
End Stage Renal Disease, Hemodialysis Complication
The Feasibility of Propofol TCI in Hemodialysis Patients Undergoing Arteriovenous Shunt Surgery
Written informed consent must be obtained before any study specific procedures are undertaken. Informed consent will be obtained during pre-operative assessment.
- Trial name
- NCT03311581
- Testing
- Propofol, Sevoflurane
- Where
- Taiwan
- Volunteers
- 47 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Heart Failure, Pulmonary Hypertension
Rivet PVS Therapy in Group 2 PH-HFpEF Canada
This clinical investigation is a prospective, multicenter, non-randomized, open-label, Early Feasibility Study to evaluate the safety, performance, and initial clinical efficacy of the Rivet PVS therapy in patients with…
- Trial name
- NCT05332873
- Testing
- Rivet Shunt
- Where
- Canada
- Sponsor
- NXT Biomedical
MASLD, Liver Cirrhosis, Alcoholic
Acquisition of Cardiac Function Parameters in MRI and Echocardiography in Patients With Ethyltoxic Liver Cirrhosis and Transjugular Intrahepatic Portosystemic Shunt (TIPSS) Placement
The aim of this clinical trial is to investigate the development of cardiac decompensation following transjugular intrahepatic portosystemic shunt (TIPSS) implantation in order to draw conclusions for future treatment methods or…
- Conditions
- MASLD, Liver Cirrhosis, Alcoholic, Cirrhosis of Liver, Heart Decompensation
- Trial name
- EVALUATION (NCT06814990)
- Testing
- Cardiac MRI, Blood samples, Echocardiography
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- Stephanie Gräger
Chronic Heart Failure
Heart Failure (HF) Interatrial Shunt Study 1
The objective of this study, is to assess the safety and performance of an interatrial shunt when implanted in patients with severe chronic heart failure.
- Trial name
- NCT02511912
- Testing
- V-Wave
- Where
- Israel
- Sponsor
- V-Wave Ltd
Liver Cirrhosis
Embolization of Large Spontaneous Portosystemic Shunts for the Prevention of Post-TIPS Hepatic Encephalopathy
The purpose of this study is to determine whether transjugular intrahepatic portosystemic shunt (TIPS) combined with large spontaneous portosystemic shunts embolization are effective in the prevention of hepatic encephalopathy…
- Trial name
- NCT02156232
- Testing
- TIPS, SPSS embolization
- Where
- China
- Volunteers
- 56 people
- Sponsor
- Air Force Military Medical University, China
Hepatic Pathology (Fibrosis, Cirrhosis, Porto Systemic Shunts)
Development of a Cognitive Tool for Rapid and Reliable Screening of Minimal Hepatic Encephalopathy: Pilot Study
The aim of this project is to evaluate the sensitivity and specificity of a cognitive test toward the presence of minimal hepatic encephalopathy (MHE).
- Trial name
- BLOCK-HE (NCT06619106)
- Testing
- Cognitive test
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Liver Cirrhosis
Skeletal Muscle Parameters of Liver Cirrhosis in Non-invasive Imaging and Outcome
The principal aim of this study is to analyse L3-SMI (skeletal muscle index) in a cohort of patients with decompensated liver cirrhosis and TIPS (transjugular intrahepatic portosystemic shunt), and compare the prognostic power…
- Trial name
- SLIM (NCT03584204)
- Testing
- imaging
- Where
- 3 sites in Germany, Italy
- Volunteers
- 400 people
- Sponsor
- University Hospital, Bonn
Liver Cirrhosis, Transjugular Intrahepatic Portosystemic Shunt (TIPS)
Incidence and Predictors of Post-TIPS Heart Failure in Patients With Cirrhosis
The purpose of this study is to conduct a prospective trial to investigate the incidence of heart failure in cirrhosis patients undergoing transjugular intrahepatic portosystemic shunt ,and to analyze the the predictors and…
- Conditions
- Liver Cirrhosis, Transjugular Intrahepatic Portosystemic Shunt (TIPS), Heart Failure
- Trial name
- NCT05596253
- Testing
- TIPS
- Where
- China
- Volunteers
- 200 people
- Sponsor
- West China Hospital
Hydrocephalus, Shunt Malfunction
Role of Endoscopic Third Ventriculostomy in Management of Malfunctioning Ventriculoperitoneal Shunt
The aim of this study is to analyze our experience in management of malfunctioning ventriculoperitoneal shunt by using endoscopic third ventriculostomy (ETV).
- Trial name
- NCT06341946
- Testing
- Endoscopic third ventriculostomy
- Volunteers
- 30 people
- Sponsor
- Sohag University
Hydrocephalus
ShuntCheck Versus Radionuclide in Evaluating Shunt Function in Symptomatic NPH Patients
The purpose of this study is to compare the accuracy of ShuntCheck (SC) and ShuntCheck plus Micro-Pumper (SC+MP) to radionuclide shunt patency testing (SPS) in evaluating shunt function in patients with adult hydrocephalus (AH)…
- Trial name
- SCNPH (NCT01323764)
- Testing
- ShuntCheck test
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- NeuroDx Development