Clinical trials: Sickle Cell-Beta0-Thalassemia
Anemia, Sickle Cell, Sickle Cell Disease
Epidemiology of Silent and Overt Strokes in Sickle Cell Disease
Sickle Cell Disease (SCD) is a rare disease occurring in an estimated 100,000 individuals, often poor and underserved, in the US.
- Conditions
- Anemia, Sickle Cell, Sickle Cell Disease, Stroke, Sickle Cell Thalassemia
- Trial name
- ESCD (NCT03376893)
- Where
- 4 sites in United States
- Volunteers
- 102 people
- Sponsor
- Vanderbilt University Medical Center
Sickle Cell Disease, Sickle Cell-Beta0-Thalassemia
Isoquercetin in Sickle Cell Anemia
This research study is being done to assess the safety and effectiveness of isoquercetin to reduce levels of soluble P-Selectin in patients with sickle cell disease. Isoquercetin is a naturally occurring flavonoid-or vitamin.
- Trial name
- NCT04474626
- Testing
- Isoquercetin
- Volunteers
- healthy volunteers welcome
- Sponsor
- Jeffrey Zwicker, MD
Sickle Cell Anemia, Sickle Cell-Beta0-Thalassemia
The Effect of Rivaroxaban in Sickle Cell Disease
The primary study hypothesis is that inhibition of factor Xa with rivaroxaban will reduce inflammation, coagulation and endothelial cell activation, and improve microvascular blood flow in patients with sickle cell disease (SCD)…
- Trial name
- NCT02072668
- Testing
- rivaroxaban
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of North Carolina, Chapel Hill