Clinical trials: Sickness Behavior, open to volunteers
Severe Mental Illness, Schizophrenia
Group Intervention for Romantic Relationships in Young Adults With Severe Mental Illness
This study evaluates a group-based intervention designed to improve romantic and social relationship skills in adults living with a severe mental illness (SMI), such as schizophrenia, bipolar disorder, or major depressive…
- Conditions
- Severe Mental Illness, Schizophrenia, Bipolar Disorder, Major Depressive Disorder
- Trial name
- A2C'estMieuxVE (NCT07316803)
- Testing
- À deux, c'est mieux (Better Together) Group Intervention
- Where
- 2 sites in France
- Volunteers
- 20 people
- Sponsor
- Centre hospitalier de Ville-Evrard, France
Critical Illness, Stress, Psychological
Virtual Reality-Based Transitional Care for ICU Survivors
This study aims to evaluate the effectiveness of a virtual reality (VR)-based transitional care program for adult survivors of intensive care unit (ICU) care.
- Conditions
- Critical Illness, Stress, Psychological, Intensive Care Units
- Trial name
- VRICU (NCT07482722)
- Testing
- Virtual Reality-Based Transitional Care
- Where
- 2 sites in Taiwan
- Volunteers
- 150 people
- Sponsor
- Mackay Memorial Hospital
Severe Mental Illness
Care Coordination and Passive Mobile Data Monitoring to Improve Mental Health Care
Providing care to individuals with serious mental illness can be challenging, requiring ongoing monitoring, treatment adjustments, and coordination of various medical and social services.
- Trial name
- CCM (NCT07549178)
- Testing
- Care Coordination Mobile
- Where
- 2 sites in United States
- Volunteers
- 400 people
- Sponsor
- VA Office of Research and Development
Chronic Pain, Schizophrenia
CBT-CP for Veterans With SMI
Chronic musculoskeletal pain has a highly negative impact on Veterans, especially those with serious mental illness (SMI). Chronic musculoskeletal pain leads to poorer mental and physical health-related functioning, representing…
- Conditions
- Chronic Pain, Schizophrenia, Psychotic Disorders, Bipolar Disorder
- Trial name
- CP-SMI (NCT06758414)
- Testing
- Cognitive Behavioral Therapy for Chronic Pain (CBT-CP), Health & Wellness (H&W)
- Where
- United States
- Volunteers
- 190 people
- Sponsor
- VA Office of Research and Development
Nicotine Dependance, Serious Mental Illness
Evaluation of Community Health Worker Support to Help People With Serious Mental Illness to Quit Smoking
The purpose of this study is to learn whether providing additional smoking cessation support through specially trained members of behavioral healthcare team helps people quit smoking and improve their health.
- Conditions
- Nicotine Dependance, Serious Mental Illness, Smoking (Tobacco) Addiction, Tobacco Cessation
- Trial name
- NCT07789132
- Testing
- Integrated CHW Support intervention, Enhanced usual care (EUC)
- Where
- United States
- Volunteers
- 937 people
- Sponsor
- Massachusetts General Hospital
Schizophrenia, Schizoaffective Disorder
Enhancing Veteran-Clinical Collaboration in VA PRRCs
Over 60% of Veterans with serious mental illness have a service-connected disability that impairs their ability to work, go to school, and/or have successful personal lives.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Delusional Disorder, Bipolar Disorder
- Trial name
- EVCC VPRRC (NCT06898879)
- Testing
- Collaborative Decision Skills Training, Leveling Up
- Where
- 3 sites in United States
- Volunteers
- 119 people
- Sponsor
- VA Office of Research and Development
Environmental Exposure, Health Behavior
The Barts Charity Children's Environmental Health Clinic
The study will be based from a newly formed NHS service, the children's environmental health service. Participants will be children with a known chronic respiratory condition.
- Conditions
- Environmental Exposure, Health Behavior, Asthma in Children, Environmental Illness
- Trial name
- BCCEHC (NCT06447974)
- Testing
- Exposure mitigations
- Where
- 2 sites in United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Mood Disorder
Studies of Brain Function and Course of Illness in Pediatric Bipolar Disorder
This study seeks to learn more about the symptoms of severe mood dysregulation in children and adolescents ages 7-17. Children and adolescents with severe mood dysregulation (SMD) display chronic anger, sadness, or irritability…
- Trial name
- NCT00025935
- Testing
- Lithium
- Where
- United States
- Volunteers
- 2,350 people
- Sponsor
- National Institute of Mental Health (NIMH)
Severe Mental Illness, Schizophrenia Spectrum &Amp; Other Psychotic Disorders
Validation and Impact of Cardiorespiratory Fitness in Severe Mental Illness - the Heart in Mind Project
This project aims to evaluate feasibility, validity and clinically applicability to systematically measure fitness in patients with severe mental illness. The research project is a validation study using a cross-sectional design.
- Conditions
- Severe Mental Illness, Schizophrenia Spectrum &Amp; Other Psychotic Disorders, Bipolar Affective Disorder
- Trial name
- NCT06743711
- Where
- Denmark
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Bjorn H. Ebdrup
Epilepsy
Effects of Nurse-Led Stigma-Reduction Education in Epilepsy
This randomized controlled trial aims to evaluate the effect of a nurse-led, stigma-reduction-based epilepsy education program on perceived/internalized stigma, concealment of epilepsy, and self-management among adults with…
- Trial name
- NCT07863310
- Testing
- Nurse-Led Stigma-Reduction-Based Epilepsy Education
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people
- Sponsor
- Muş Alparslan University
Functional Neurological Disorder, Functional Movement Disorder
The Effect of Psychoeducational Diagnosis Communication on Perception of Illness, Satisfaction, and Behavioral Intentions Among Patients With Functional Neurological Movement Disorders
Functional neurological movement disorders are common conditions that can lead to significant limitations in daily life. They result from a functional disorder in the brain.
- Trial name
- NCT07588282
- Testing
- Psychoeducational communication guide for first-diagnosis of FND
- Where
- Austria
- Volunteers
- 35 people
- Sponsor
- Medical University of Graz
Serious Mental Illness, Financial Hardship
Financial Tools Access and Navigation (FinTAN)
The specific aims of this study are to: i) collaboratively create a Financial Tools Access and Navigation (FinTAN) guide to assist persons and care providers to identify the potential utility of relevant financial products, and…
- Trial name
- NCT07920874
- Testing
- FinTAN guide
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Yale University
Designating a Healthcare Proxy
Encouraging Older Adults and Adults With Serious Illness to Designate a Health Care Proxy
This study is a Stage III randomized trial to encourage patients in advance of a health care appointment to designate a healthcare proxy.
- Trial name
- NCT07290478
- Testing
- Mailer, Provider Request, Pre-commitment Prompt
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- University of Southern California
Critical Illness Recovery, Behavioral Health Concerns
Behavioral Health Collaborative Care Model in Post-ICU Clinic Family Pilot
This pilot study evaluates the feasibility and acceptability of implementing a Behavioral Health Collaborative Care Model (BH CoCM) for family members of ICU survivors.
- Conditions
- Critical Illness Recovery, Behavioral Health Concerns, Anxiety, Depression - Major Depressive Disorder
- Trial name
- NCT07390786
- Testing
- Behavioral Treatment
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Medical University of South Carolina
Obesity
Interoception and Illness Perception Before and After Bariatric Surgery: Impact on Disordered Eating (Interoceptiv-BAR)
Obesity is associated with alterations in the perception and interpretation of internal bodily signals (interoception), which may influence eating behaviors, emotional regulation, and long-term weight outcomes.
- Trial name
- NCT07594275
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Loneliness, Mental Well-being
Creating Encounters Between Generations - Together Instead of Alone (GemsE)
Elderly people and children and young people (CYP) and from families with mentally ill parents are particularly affected by loneliness.
- Conditions
- Loneliness, Mental Well-being, Health-related Quality of Life
- Trial name
- GemsE (NCT07581171)
- Testing
- Mechanisms and effectiveness of intergenerational tandems
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Tobacco Dependence
Harm Reduction for Smokers With Mental Illness
To compare the efficacy of e-cigarette (e-cig) provision with or without behavioral support (SWITCH IT) delivered via telehealth to reduce harm among smokers with MI who cannot quit smoking and are not ready to pursue cessation…
- Trial name
- NCT06543407
- Testing
- SWITCH IT, E-cig Provision Only
- Where
- 2 sites in United States
- Volunteers
- 250 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Sexual and Gender Minorities, Hospice
Intervention to Collect and Utilize Sexual Orientation and Gender Identity (SOGI) Information in Hospice
Older sexual and gender minority (SGM) patients are at risk for receiving inequitable end-of-life care; those with Alzheimer's disease and related dementias (ADRD) are at particularly high risk.
- Conditions
- Sexual and Gender Minorities, Hospice, Alzheimer's Disease and Related Dementias
- Trial name
- NCT05877391
- Testing
- SGM Communication Intervention
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Mental Disorder, Pharmacogenetics
Pharmacogenomics-Supported Psychotropic Prescribing Trial
Investigate the feasibility and utility of implementing pharmacogenetic testing for adults (aged 18 and older) seeking care for mental illness in Manitoba.
- Conditions
- Mental Disorder, Pharmacogenetics, Adverse Drug Reaction (ADR), Effectiveness
- Trial name
- PGx-SUPPORT (NCT06929533)
- Testing
- Pharmacogenetic Testing
- Where
- 2 sites in Canada
- Volunteers
- 200 people
- Sponsor
- University of Manitoba
Alcohol Abuse, Alcohol Use Disorder
The Effect of Comorbid Alcohol/Substance Use
Study Design This study was designed as a comparative, cross-sectional case-control study examining the effect of comorbid alcohol and substance use disorder (ASUD) on clinical course and social inclusion among individuals with…
- Conditions
- Alcohol Abuse, Alcohol Use Disorder, Substance Use Disorders, Severe Mental Disorder
- Trial name
- NCT07692984
- Testing
- case (comorbid diagnosis), control
- Where
- Turkey (Türkiye)
- Volunteers
- 297 people
- Sponsor
- Abant Izzet Baysal University